Page last updated: 2024-11-03

prilocaine and Dysesthesia

prilocaine has been researched along with Dysesthesia in 16 studies

Prilocaine: A local anesthetic that is similar pharmacologically to LIDOCAINE. Currently, it is used most often for infiltration anesthesia in dentistry.
prilocaine : An amino acid amide in which N-propyl-DL-alanine and 2-methylaniline have combined to form the amide bond; used as a local anaesthetic.

Research Excerpts

ExcerptRelevanceReference
"After 5 days of treatment, heat pain hyperalgesia persisted on both forearms; however, it was significantly less on the EMLA-treated forearm vs the vehicle-treated site (p < 0."2.69Effect of EMLA pre-treatment on capsaicin-induced burning and hyperalgesia. ( Maibach, HI; Rowbotham, MC; Yosipovitch, G, 1999)
"Prilocaine results in a lower incidence of transient neurological symptoms than lidocaine intrathecally and therefore it is more suitable for short surgical procedures."2.69The incidence of transient neurological symptoms after spinal anaesthesia with lidocaine compared to prilocaine. ( de Weert, K; Dirksen, R; Gielen, M; Slappendel, R; Traksel, M; Weber, E, 2000)
"Paresthesia is defined as an abnormal sensation, such as burning, pricking, tickling, or tingling."2.46Paresthesias in dentistry. ( Haas, DA; Moore, PA, 2010)
" A case/non-case study of spontaneous adverse events recorded in FAERS (FDA Adverse Event Reporting System) between 2004 and 2011 was performed."1.42Paraesthesia after local anaesthetics: an analysis of reports to the FDA Adverse Event Reporting System. ( Gabusi, A; Gissi, DB; Montebugnoli, L; Piccinni, C; Poluzzi, E, 2015)
"Lidocaine was associated with 25 percent of cases, articaine with 33 percent of cases, and prilocaine with 34 percent of cases."1.38Permanent nerve damage from inferior alveolar nerve blocks: a current update. ( Pogrel, MA, 2012)
"The authors obtained reports of paresthesia involving dental local anesthetics during the period from November 1997 through August 2008 from the U."1.36Occurrence of paresthesia after dental local anesthetic administration in the United States. ( Gaffen, AS; Garisto, GA; Haas, DA; Lawrence, HP; Tenenbaum, HC, 2010)
"Chronic pain is often a symptom after local anaesthetic-induced nerve injury."1.36Trigeminal nerve injuries in relation to the local anaesthesia in mandibular injections. ( Adey-Viscuso, D; Meechan, JG; Renton, T; Yilmaz, Z, 2010)
"All cases of nonsurgical paresthesia reported from 1999 to 2008 were reviewed; cases involving surgical procedures were excluded."1.35Retrospective review of voluntary reports of nonsurgical paresthesia in dentistry. ( Gaffen, AS; Haas, DA, 2009)
"The 34 percent [corrected] incidence of dysesthesia in the patients in this study is of concern."1.31Permanent nerve involvement resulting from inferior alveolar nerve blocks. ( Pogrel, MA; Thamby, S, 2000)
"A retrospective study of paresthesia following the injection of local anesthetic in dentistry was conducted by examining every report of paresthesia recorded by Ontario's Professional Liability Program from 1973 to 1993, inclusive."1.29A 21 year retrospective study of reports of paresthesia following local anesthetic administration. ( Haas, DA; Lennon, D, 1995)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (18.75)18.2507
2000's7 (43.75)29.6817
2010's6 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Piccinni, C1
Gissi, DB1
Gabusi, A1
Montebugnoli, L1
Poluzzi, E1
Bogaerts, P1
Gaffen, AS2
Haas, DA4
Garisto, GA1
Lawrence, HP1
Tenenbaum, HC1
Moore, PA2
Hersh, EV1
Renton, T1
Adey-Viscuso, D1
Meechan, JG1
Yilmaz, Z1
Pogrel, MA2
Dower, JS1
Moppett, IK1
Szypula, K1
Yeoman, PM1
Celebi, N1
Sahin, A1
Canbay, O1
Uzümcügil, F1
Aypar, U1
Lennon, D1
Machado, HS1
Bastos, RS1
Yosipovitch, G1
Maibach, HI1
Rowbotham, MC1
Thamby, S1
de Weert, K1
Traksel, M1
Gielen, M1
Slappendel, R1
Weber, E1
Dirksen, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Is the Direct Inferior Alveolar Nerve Block Required for Third Lower Molar Extraction?[NCT03443726]120 participants (Actual)Interventional2017-06-10Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for prilocaine and Dysesthesia

ArticleYear
Paresthesias in dentistry.
    Dental clinics of North America, 2010, Volume: 54, Issue:4

    Topics: Anesthesia, Dental; Anesthetics, Local; Animals; Carticaine; Clinical Trials as Topic; Dental Care;

2010
A review of paresthesia in association with administration of local anesthesia.
    Dentistry today, 2003, Volume: 22, Issue:2

    Topics: Anesthesia, Dental; Anesthetics, Local; Bupivacaine; Carticaine; Humans; Lidocaine; Lingual Nerve; M

2003

Trials

3 trials available for prilocaine and Dysesthesia

ArticleYear
Comparison of EMLA and lidocaine iontophoresis for cannulation analgesia.
    European journal of anaesthesiology, 2004, Volume: 21, Issue:3

    Topics: Adult; Aged; Analgesia; Anesthetics, Combined; Anesthetics, Local; Catheterization, Peripheral; Doub

2004
Effect of EMLA pre-treatment on capsaicin-induced burning and hyperalgesia.
    Acta dermato-venereologica, 1999, Volume: 79, Issue:2

    Topics: Administration, Cutaneous; Adult; Anesthetics, Local; Capsaicin; Female; Humans; Hyperalgesia; Lidoc

1999
The incidence of transient neurological symptoms after spinal anaesthesia with lidocaine compared to prilocaine.
    Anaesthesia, 2000, Volume: 55, Issue:10

    Topics: Adolescent; Adult; Aged; Anesthesia, Spinal; Anesthetics, Local; Double-Blind Method; Female; Humans

2000

Other Studies

11 other studies available for prilocaine and Dysesthesia

ArticleYear
Paraesthesia after local anaesthetics: an analysis of reports to the FDA Adverse Event Reporting System.
    Basic & clinical pharmacology & toxicology, 2015, Volume: 117, Issue:1

    Topics: Adverse Drug Reaction Reporting Systems; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local;

2015
[Sensory injury to the lingual nerve after nerve block at the lingula mandibulae].
    Revue belge de medecine dentaire, 2007, Volume: 62, Issue:3

    Topics: Ageusia; Anesthesia, Dental; Female; Humans; Insurance, Dental; Liability, Legal; Lidocaine; Lingual

2007
Retrospective review of voluntary reports of nonsurgical paresthesia in dentistry.
    Journal (Canadian Dental Association), 2009, Volume: 75, Issue:8

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anesthesia, Dental; Anesthetics, Local; Can

2009
Occurrence of paresthesia after dental local anesthetic administration in the United States.
    Journal of the American Dental Association (1939), 2010, Volume: 141, Issue:7

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Anesthesia, Dental; Anesthetics, L

2010
Oral paresthesia.
    Journal of the American Dental Association (1939), 2010, Volume: 141, Issue:11

    Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Humans; Lingual Nerve; Nerve Block; Paresthesia;

2010
Trigeminal nerve injuries in relation to the local anaesthesia in mandibular injections.
    British dental journal, 2010, Volume: 209, Issue:9

    Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Local; Chin; Cranial Nerve Injuries; Female; Gingiva; H

2010
Permanent nerve damage from inferior alveolar nerve blocks: a current update.
    Journal of the California Dental Association, 2012, Volume: 40, Issue:10

    Topics: Anesthesia, Dental; Anesthetics, Local; California; Carticaine; Cranial Nerve Diseases; Humans; Lido

2012
Abdominal pain related to mitochondrial neurogastrointestinal encephalomyopathy syndrome may benefit from splanchnic nerve blockade.
    Paediatric anaesthesia, 2006, Volume: 16, Issue:10

    Topics: Abdominal Pain; Adolescent; Amines; Analgesics; Anesthetics, Local; Cyclohexanecarboxylic Acids; Ele

2006
A 21 year retrospective study of reports of paresthesia following local anesthetic administration.
    Journal (Canadian Dental Association), 1995, Volume: 61, Issue:4

    Topics: Adult; Aged; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Binomial Distribution; Carti

1995
Inadequate tourniquet inflation associated with a case of prilocaine toxicity.
    European journal of anaesthesiology, 1998, Volume: 15, Issue:2

    Topics: Aged; Anesthetics, Local; Carpal Tunnel Syndrome; Female; Humans; Paresthesia; Prilocaine; Tachycard

1998
Permanent nerve involvement resulting from inferior alveolar nerve blocks.
    Journal of the American Dental Association (1939), 2000, Volume: 131, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Dental; Anesthetics, Local; Causalgia; Female; Humans; I

2000