Page last updated: 2024-11-03

prilocaine and Chronic Disease

prilocaine has been researched along with Chronic Disease in 11 studies

Prilocaine: A local anesthetic that is similar pharmacologically to LIDOCAINE. Currently, it is used most often for infiltration anesthesia in dentistry.
prilocaine : An amino acid amide in which N-propyl-DL-alanine and 2-methylaniline have combined to form the amide bond; used as a local anaesthetic.

Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).

Research Excerpts

ExcerptRelevanceReference
"Although the lignocaine (lidocaine)-prilocaine cream EMLA has been extensively studied for the relief of acute treatment-related pain from sharp leg ulcer debridement, no data exist on systemic absorption from prolonged application in patients with chronically painful ulcers."9.09Plasma concentrations of lignocaine and prilocaine after a 24-h application of analgesic cream (EMLA) to leg ulcers. ( Lillieborg, S; Stymne, B, 2001)
"It has not yet been clarified whether prilocaine-induced methemoglobinemia is a problem in patients with chronic anemia."7.67[Supraclavicular plexus blockade using prilocaine in patients with chronic anemia]. ( Viell, B; Wald-Oboussier, G, 1989)
"This multicentre, double-blind, placebo-controlled, parallel-group study assessed the efficacy and safety of using Emla (lignocaine/prilocaine) anaesthetic cream to achieve pain control during sharp debridement of chronic leg ulcers of arterial, venous or arteriovenous aetiology."5.09Using a topical anaesthetic cream to reduce pain during sharp debridement of chronic leg ulcers. ( Baxter, M; Gottschalk, R; Lycka, B; Murphy, F; Nevin, K; Rosenthal, D, 2001)
"Although the lignocaine (lidocaine)-prilocaine cream EMLA has been extensively studied for the relief of acute treatment-related pain from sharp leg ulcer debridement, no data exist on systemic absorption from prolonged application in patients with chronically painful ulcers."5.09Plasma concentrations of lignocaine and prilocaine after a 24-h application of analgesic cream (EMLA) to leg ulcers. ( Lillieborg, S; Stymne, B, 2001)
"It has not yet been clarified whether prilocaine-induced methemoglobinemia is a problem in patients with chronic anemia."3.67[Supraclavicular plexus blockade using prilocaine in patients with chronic anemia]. ( Viell, B; Wald-Oboussier, G, 1989)
"Bupivacaine help the lower pain values and less additional painkiller need after FESS."2.82Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective? ( Arıkan, OK; Haytoğlu, S; Kuran, G; Muluk, NB, 2016)
"Atypical odontalgia is a distressing and unusual chronic orofacial pain condition."2.69Analysis of 50 patients with atypical odontalgia. A preliminary report on pharmacological procedures for diagnosis and treatment. ( Chisholm, K; Cousins, MJ; Vickers, ER; Walker, S, 1998)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's3 (27.27)18.2507
2000's4 (36.36)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Purcell, A1
Buckley, T1
Fethney, J1
King, J1
Moyle, W1
Marshall, AP1
Haytoğlu, S1
Kuran, G1
Muluk, NB1
Arıkan, OK1
Rosenthal, D1
Murphy, F1
Gottschalk, R1
Baxter, M1
Lycka, B1
Nevin, K1
Sabatino, MD1
Borrelli, M1
Cautiero, P1
Romano, M1
Parmeggiani, P1
Marte, A1
Gottehrer, NR1
Vickers, ER1
Cousins, MJ1
Walker, S1
Chisholm, K1
Lewis, RN1
Stymne, B1
Lillieborg, S1
Hahn, J1
Wald-Oboussier, G1
Viell, B1
Oliver, LP1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Local Anesthesia With Lidocaine During Insertion and Removal of Nasal Packing[NCT04519463]Early Phase 160 participants (Anticipated)Interventional2020-09-30Not yet recruiting
Does the Use of Bupivacaine Soaked Vaginal Packing Following Vaginal Surgery Decrease Postoperative Pain?[NCT03266926]140 participants (Actual)Observational [Patient Registry]2017-02-01Completed
Efficacy of Inhaled 50% Equimolar Nitrous Oxide/Oxygen Gas Premix (Kalinox®) as Compared to Topically Administered 5% Eutectic Mixture of Lidocaine/Prilocaine (EMLA®) in Chronic Leg Ulcer Debridement[NCT02696460]21 participants (Actual)Interventional2010-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

6 trials available for prilocaine and Chronic Disease

ArticleYear
The Effectiveness of EMLA as a Primary Dressing on Painful Chronic Leg Ulcers: Effects on Wound Healing and Health-Related Quality of Life.
    The international journal of lower extremity wounds, 2017, Volume: 16, Issue:3

    Topics: Aged; Aged, 80 and over; Australia; Chronic Disease; Cross-Over Studies; Female; Follow-Up Studies;

2017
Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective?
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016, Volume: 273, Issue:7

    Topics: Adolescent; Adult; Amides; Anesthetics, Local; Bandages; Bupivacaine; Chronic Disease; Endoscopy; Fe

2016
Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective?
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016, Volume: 273, Issue:7

    Topics: Adolescent; Adult; Amides; Anesthetics, Local; Bandages; Bupivacaine; Chronic Disease; Endoscopy; Fe

2016
Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective?
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016, Volume: 273, Issue:7

    Topics: Adolescent; Adult; Amides; Anesthetics, Local; Bandages; Bupivacaine; Chronic Disease; Endoscopy; Fe

2016
Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective?
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016, Volume: 273, Issue:7

    Topics: Adolescent; Adult; Amides; Anesthetics, Local; Bandages; Bupivacaine; Chronic Disease; Endoscopy; Fe

2016
Using a topical anaesthetic cream to reduce pain during sharp debridement of chronic leg ulcers.
    Journal of wound care, 2001, Volume: 10, Issue:1

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Chronic Disease; Debr

2001
Analysis of 50 patients with atypical odontalgia. A preliminary report on pharmacological procedures for diagnosis and treatment.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 1998, Volume: 85, Issue:1

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthetics, Combined; Anesthetics, Local;

1998
The use of combined suprascapular and circumflex (articular branches) nerve blocks in the management of chronic arthritis of the shoulder joint.
    European journal of anaesthesiology, 1999, Volume: 16, Issue:1

    Topics: Aged; Aged, 80 and over; Anesthetics, Local; Arthritis, Rheumatoid; Chronic Disease; Female; Humans;

1999
Plasma concentrations of lignocaine and prilocaine after a 24-h application of analgesic cream (EMLA) to leg ulcers.
    The British journal of dermatology, 2001, Volume: 145, Issue:4

    Topics: Aged; Aged, 80 and over; Anesthetics, Combined; Anesthetics, Local; Chronic Disease; Dose-Response R

2001

Other Studies

5 other studies available for prilocaine and Chronic Disease

ArticleYear
[Painful defecation and chronic functional constipation in children: Diagnosis and treatment].
    Minerva pediatrica, 2006, Volume: 58, Issue:3

    Topics: Anal Canal; Anesthetics, Local; Child; Child, Preschool; Chronic Disease; Constipation; Defecation;

2006
Antimicrobials in periodontics: controlling chronic disease.
    Dentistry today, 2008, Volume: 27, Issue:4

    Topics: Anesthetics, Combined; Anesthetics, Local; Anti-Bacterial Agents; Bacteroidaceae Infections; Bactero

2008
[Comments on the paper by G. Wald-Oboussier and B. Veill. Supraclavicular plexus blockade using prilocaine in patients with chronic anemia].
    Regional-Anaesthesie, 1990, Volume: 13, Issue:4

    Topics: Anemia; Cervical Plexus; Chronic Disease; Humans; Methemoglobinemia; Nerve Block; Prilocaine

1990
[Supraclavicular plexus blockade using prilocaine in patients with chronic anemia].
    Regional-Anaesthesie, 1989, Volume: 12, Issue:2

    Topics: Aged; Anemia; Brachial Plexus; Chronic Disease; Female; Humans; Kidney Failure, Chronic; Methemoglob

1989
Local anaesthesia--a review of practice.
    Australian dental journal, 1974, Volume: 19, Issue:5

    Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Antidepressive Agents; Chronic Disease; D

1974