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prilocaine and Cancer of Prostate

prilocaine has been researched along with Cancer of Prostate in 11 studies

Prilocaine: A local anesthetic that is similar pharmacologically to LIDOCAINE. Currently, it is used most often for infiltration anesthesia in dentistry.
prilocaine : An amino acid amide in which N-propyl-DL-alanine and 2-methylaniline have combined to form the amide bond; used as a local anaesthetic.

Research Excerpts

ExcerptRelevanceReference
"What's known on the subject? and What does the study add? Study Type - Harm Reduction RCT Level of Evidence 1b The combination of perianal-intrarectal lidocaine-prilocaine cream and periprostatic nerve block effectively counteracts probe and sampling related pain during transrectal prostate biopsy, but not pain due to periprostatic infiltration."9.16Combined perianal-intrarectal (PI) lidocaine-prilocaine (LP) cream and lidocaine-ketorolac gel provide better pain relief than combined PI LP cream and periprostatic nerve block during transrectal prostate biopsy. ( Bufo, P; Carrieri, G; Cormio, L; Lorusso, F; Pagliarulo, V; Perrone, A; Sanguedolce, F; Selvaggio, O, 2012)
"Our findings suggest that the combination of perianal-intrarectal lidocaine-prilocaine cream and periprostatic nerve block provides better pain control than the 2 modalities alone during the sampling part of transrectal ultrasound guided prostate biopsy with no increase in the complication rate."9.14Combination of perianal-intrarectal lidocaine-prilocaine cream and periprostatic nerve block for pain control during transrectal ultrasound guided prostate biopsy: a randomized, controlled trial. ( Autorino, R; Barbone, F; De Maria, M; Di Lorenzo, G; Giannarini, G; Manassero, F; Mogorovich, A; Morelli, G; Selli, C; Valent, F, 2009)
"Perianal anesthesia with lidocaine-prilocaine cream may solely be sufficient to decrease the pain during prostate biopsy."9.14Is only perianal anesthesia with lidocaine-prilocaine cream sufficient to decrease the pain during transrectal ultrasound-guided prostate biopsy? A prospective randomized study. ( Kandirali, E; Metin, A; Semercioz, A; Serin, E; Ulukaradag, E; Uysal, B, 2009)
"To compare pain control results between periprostatic nerve block alone and combined with topical prilocaine-lidocaine cream as local anesthesia of prostate biopsy."9.13Topical prilocaine-lidocaine cream combined with peripheral nerve block improves pain control in prostatic biopsy: results from a prospective randomized trial. ( Briganti, A; Dehò, F; Di Girolamo, V; Gallina, A; Montorsi, F; Raber, M; Rigatti, P; Roscigno, M; Salonia, A; Scattoni, V, 2008)
"Lidocaine-prilocaine cream was most effective on probe-related pain, whereas lidocaine-ketorolac gel was most effective on sampling-related pain."5.17Noninfiltrative anesthesia for transrectal prostate biopsy: a randomized prospective study comparing lidocaine-prilocaine cream and lidocaine-ketorolac gel. ( Bufo, P; Carrieri, G; Cormio, L; Lorusso, F; Pagliarulo, V; Perrone, A; Sanguedolce, F; Selvaggio, O, 2013)
"What's known on the subject? and What does the study add? Study Type - Harm Reduction RCT Level of Evidence 1b The combination of perianal-intrarectal lidocaine-prilocaine cream and periprostatic nerve block effectively counteracts probe and sampling related pain during transrectal prostate biopsy, but not pain due to periprostatic infiltration."5.16Combined perianal-intrarectal (PI) lidocaine-prilocaine (LP) cream and lidocaine-ketorolac gel provide better pain relief than combined PI LP cream and periprostatic nerve block during transrectal prostate biopsy. ( Bufo, P; Carrieri, G; Cormio, L; Lorusso, F; Pagliarulo, V; Perrone, A; Sanguedolce, F; Selvaggio, O, 2012)
"Our findings suggest that the combination of perianal-intrarectal lidocaine-prilocaine cream and periprostatic nerve block provides better pain control than the 2 modalities alone during the sampling part of transrectal ultrasound guided prostate biopsy with no increase in the complication rate."5.14Combination of perianal-intrarectal lidocaine-prilocaine cream and periprostatic nerve block for pain control during transrectal ultrasound guided prostate biopsy: a randomized, controlled trial. ( Autorino, R; Barbone, F; De Maria, M; Di Lorenzo, G; Giannarini, G; Manassero, F; Mogorovich, A; Morelli, G; Selli, C; Valent, F, 2009)
"Perianal anesthesia with lidocaine-prilocaine cream may solely be sufficient to decrease the pain during prostate biopsy."5.14Is only perianal anesthesia with lidocaine-prilocaine cream sufficient to decrease the pain during transrectal ultrasound-guided prostate biopsy? A prospective randomized study. ( Kandirali, E; Metin, A; Semercioz, A; Serin, E; Ulukaradag, E; Uysal, B, 2009)
"To compare pain control results between periprostatic nerve block alone and combined with topical prilocaine-lidocaine cream as local anesthesia of prostate biopsy."5.13Topical prilocaine-lidocaine cream combined with peripheral nerve block improves pain control in prostatic biopsy: results from a prospective randomized trial. ( Briganti, A; Dehò, F; Di Girolamo, V; Gallina, A; Montorsi, F; Raber, M; Rigatti, P; Roscigno, M; Salonia, A; Scattoni, V, 2008)
"Topical anaesthesia with prilocaine-lidocaine cream significantly reduced pain at transrectal probe insertion and during the biopsy procedure."5.11Perianal and intrarectal anaesthesia for transrectal biopsy of the prostate: a prospective randomized study comparing lidocaine-prilocaine cream and placebo. ( Montorsi, F; Raber, M; Rigatti, P; Roscigno, M; Scattoni, V, 2005)
"Pain was evaluated using an 11-point visual analog scale questionnaire."2.71Unilateral pudendal nerve blockade for relief of all pain during transrectal ultrasound-guided biopsy of the prostate: a randomized, double-blind, placebo-controlled study. ( Adsan, O; Cetinkaya, M; Inal, G; Kaygisiz, O; Ozdoğan, L; Uğurlu, O, 2004)
"Pain was evaluated using a visual analog scale (VAS) after each core biopsy."2.71Local anesthesia in transrectal ultrasound-guided prostate biopsy: EMLA cream as a new alternative technique. ( Akpinar, S; Başar, H; Başar, MM; Batislam, E; Ozcan, S, 2005)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (81.82)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Giannarini, G3
Autorino, R1
Valent, F1
Mogorovich, A2
Manassero, F1
De Maria, M2
Morelli, G1
Barbone, F1
Di Lorenzo, G1
Selli, C3
Kandirali, E1
Ulukaradag, E1
Uysal, B1
Serin, E1
Semercioz, A1
Metin, A1
Cormio, L2
Lorusso, F2
Selvaggio, O2
Perrone, A2
Sanguedolce, F2
Pagliarulo, V2
Bufo, P2
Carrieri, G2
Adsan, O1
Inal, G1
Ozdoğan, L1
Kaygisiz, O1
Uğurlu, O1
Cetinkaya, M1
Başar, H2
Başar, MM1
Ozcan, S1
Akpinar, S1
Batislam, E1
Raber, M2
Scattoni, V2
Roscigno, M2
Rigatti, P2
Montorsi, F2
von Knobloch, R1
Dehò, F1
Briganti, A1
Salonia, A1
Gallina, A1
Di Girolamo, V1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Anorectal Application of 5% Lidocaine Cream Reduces Pain Prior to Periprostatic Nerve Block During Transrectal Ultrasound Guided Biopsy: Randomized, Prospective Controlled Study[NCT04064047]284 participants (Actual)Interventional2016-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

8 trials available for prilocaine and Cancer of Prostate

ArticleYear
Combination of perianal-intrarectal lidocaine-prilocaine cream and periprostatic nerve block for pain control during transrectal ultrasound guided prostate biopsy: a randomized, controlled trial.
    The Journal of urology, 2009, Volume: 181, Issue:2

    Topics: Administration, Topical; Aged; Analgesia; Analysis of Variance; Biopsy, Needle; Chi-Square Distribut

2009
Is only perianal anesthesia with lidocaine-prilocaine cream sufficient to decrease the pain during transrectal ultrasound-guided prostate biopsy? A prospective randomized study.
    Urologia internationalis, 2009, Volume: 82, Issue:3

    Topics: Administration, Rectal; Aged; Anesthetics, Combined; Anesthetics, Local; Biopsy; Humans; Lidocaine;

2009
Noninfiltrative anesthesia for transrectal prostate biopsy: a randomized prospective study comparing lidocaine-prilocaine cream and lidocaine-ketorolac gel.
    Urologic oncology, 2013, Volume: 31, Issue:1

    Topics: Administration, Rectal; Aged; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Biopsy, N

2013
Combined perianal-intrarectal (PI) lidocaine-prilocaine (LP) cream and lidocaine-ketorolac gel provide better pain relief than combined PI LP cream and periprostatic nerve block during transrectal prostate biopsy.
    BJU international, 2012, Volume: 109, Issue:12

    Topics: Administration, Rectal; Aged; Anesthetics, Combined; Anesthetics, Local; Biopsy; Cyclooxygenase Inhi

2012
Unilateral pudendal nerve blockade for relief of all pain during transrectal ultrasound-guided biopsy of the prostate: a randomized, double-blind, placebo-controlled study.
    Urology, 2004, Volume: 64, Issue:3

    Topics: Aged; Anesthetics, Local; Autonomic Nerve Block; Biopsy, Needle; Double-Blind Method; Humans; Male;

2004
Local anesthesia in transrectal ultrasound-guided prostate biopsy: EMLA cream as a new alternative technique.
    Scandinavian journal of urology and nephrology, 2005, Volume: 39, Issue:2

    Topics: Administration, Rectal; Aged; Anesthesia, Local; Anesthetics, Local; Biopsy; Endosonography; Humans;

2005
Perianal and intrarectal anaesthesia for transrectal biopsy of the prostate: a prospective randomized study comparing lidocaine-prilocaine cream and placebo.
    BJU international, 2005, Volume: 96, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Combined; Anesthetics, Local; Biopsy, Needle; Double-Bl

2005
Topical prilocaine-lidocaine cream combined with peripheral nerve block improves pain control in prostatic biopsy: results from a prospective randomized trial.
    European urology, 2008, Volume: 53, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Combined; Anesthetics, Local; Biopsy, Needle; Follow-Up

2008

Other Studies

3 other studies available for prilocaine and Cancer of Prostate

ArticleYear
Perianal and intrarectal anaesthesia for transrectal biopsy of the prostate: a prospective randomized study comparing lidocaine-prilocaine cream and placebo.
    BJU international, 2006, Volume: 97, Issue:5

    Topics: Anesthetics, Combined; Biopsy, Needle; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Ma

2006
Editorial comment on: topical prilocaine-lidocaine cream combined with peripheral nerve block improves pain control in prostatic biopsy: results from a prospective randomized trial.
    European urology, 2008, Volume: 53, Issue:5

    Topics: Anesthetics, Combined; Anesthetics, Local; Biopsy, Needle; Humans; Lidocaine; Male; Nerve Block; Oin

2008
Editorial comment on: topical prilocaine-lidocaine cream combined with peripheral nerve block improves pain control in prostatic biopsy: results from a prospective randomized trial.
    European urology, 2008, Volume: 53, Issue:5

    Topics: Anesthetics, Combined; Anesthetics, Local; Biopsy, Needle; Humans; Lidocaine; Male; Nerve Block; Oin

2008