Page last updated: 2024-11-03

prilocaine and Bouillaud Disease

prilocaine has been researched along with Bouillaud Disease in 1 studies

Prilocaine: A local anesthetic that is similar pharmacologically to LIDOCAINE. Currently, it is used most often for infiltration anesthesia in dentistry.
prilocaine : An amino acid amide in which N-propyl-DL-alanine and 2-methylaniline have combined to form the amide bond; used as a local anaesthetic.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adams, V1
Marley, J1
McCarroll, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Methemoglobin Levels in Generally Anesthetized Pediatric Dental Patients Receiving Prilocaine Versus Lidocaine[NCT01402869]91 participants (Actual)Interventional2011-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Delta Methemoglobin Blood Level

Change in percentage of methemoglobin in blood from baseline level to peak level (NCT01402869)
Timeframe: From administration of local anesthetic or start of restorative procedures to time at which maximum methemoglobin blood level was documented during dental treatment for an average of 2 hours

Interventionpercentage of methemoglobin in blood (Mean)
Prilocaine2.73
Lidocaine0.78
No Local Anesthetic0.76

Peak Methemoglobin Blood Levels

The maximum percentage of methemoglobin in blood (NCT01402869)
Timeframe: Measured at 10 second intervals during dental treatment for an average of 2 hours

Interventionpercentage of methemoglobin in blood (Mean)
Prilocaine3.55
Lidocaine1.63
No Local Anesthetic1.60

Time to Peak Methemoglobin Blood Levels

The length of time between the administration of local anesthetic (Prilocaine and Lidocaine Groups) or start of restorative dental procedures (No local anesthetic Group) and the time at which the maximum methemoglobin blood level is observed. (NCT01402869)
Timeframe: Measured at 10 second intervals during dental treatment for an average of 2 hours

Interventionminutes (Mean)
Prilocaine62.73
Lidocaine57.50
No Local Anesthetic29.50

Other Studies

1 other study available for prilocaine and Bouillaud Disease

ArticleYear
Prilocaine induced methaemoglobinaemia in a medically compromised patient. Was this an inevitable consequence of the dose administered?
    British dental journal, 2007, Nov-24, Volume: 203, Issue:10

    Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Dental Care for Chronically Ill; Dose-Res

2007