prilocaine has been researched along with Anxiety in 20 studies
Prilocaine: A local anesthetic that is similar pharmacologically to LIDOCAINE. Currently, it is used most often for infiltration anesthesia in dentistry.
prilocaine : An amino acid amide in which N-propyl-DL-alanine and 2-methylaniline have combined to form the amide bond; used as a local anaesthetic.
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The local analgesic efficacy of a cream formulation of lidocaine and prilocaine (EMLA) in reducing pain at venous cannulation was investigated in children scheduled for elective surgery." | 9.06 | Reduction of pain at venous cannulation in children with a eutectic mixture of lidocaine and prilocaine (EMLA cream): comparison with placebo cream and no local premedication. ( Iisalo, E; Kanto, J; Lindberg, R; Manner, T; Scheinin, M; Viinamäki, O, 1987) |
| "To investigate the effect of local usage of prilocaine and ıts combination with tramadol on the pain and anxiety levels of patients during nasal packing removal." | 7.96 | Effect of prilocaine and its combination with tramadol on anxiety and pain during nasal packing removal. ( Arslan, E; Tulaci, KG; Tulaci, RG; Yazici, H, 2020) |
| "The pretreatment with nitrous oxide is a time effective and safe method for use at paediatric outpatient departments to reduce pain, facilitate venous cannulation, and thereby reduce the number of costly cancellations of planned procedures." | 5.11 | Nitrous oxide inhalation is a safe and effective way to facilitate procedures in paediatric outpatient departments. ( Ekbom, K; Jakobsson, J; Marcus, C, 2005) |
| "The efficacy of lignocaine-prilocaine cream (EMLA) and amethocaine gel (Ametop) in reducing the pain and distress of venepuncture was compared in a single-blind randomized study of 34 children aged 1-14 y." | 5.09 | Comparison of lignocaine-prilocaine cream and amethocaine gel for local analgesia before venepuncture in children. ( Choy, L; Collier, J; Watson, AR, 1999) |
| "5% prilocaine) in reducing distress, anxiety, and pain associated with phlebotomy in pediatric outpatients." | 5.08 | EMLA cream as a topical anesthetic before office phlebotomy in children. ( Schwartz, R; Sheridan, MJ; Young, SS, 1996) |
| "Emla cream combined with nitrous oxide is effective for venous cannulation in providing satisfactory analgesia and in controlling anxiety elicited by the vision of needle." | 5.08 | [Combination of Emla cream and nitrous oxide for venous cannulation in children]. ( Benaguida, M; Benslama, A; Idali, B; Mjahed, K; Sadraoui, A, 1997) |
| "The local analgesic efficacy of EMLA Cream (a eutectic mixture of lidocaine and prilocaine; Astra Pharmaceuticals, Sweden) in reducing the pain at Venous cannulation was investigated in a randommized blind study in 75 children scheduled for elective surgery." | 5.06 | Our experience with EMLA Cream (for painless venous cannulation in children). ( Johl, KS; Wig, J, 1990) |
| "The local analgesic efficacy of a cream formulation of lidocaine and prilocaine (EMLA) in reducing pain at venous cannulation was investigated in children scheduled for elective surgery." | 5.06 | Reduction of pain at venous cannulation in children with a eutectic mixture of lidocaine and prilocaine (EMLA cream): comparison with placebo cream and no local premedication. ( Iisalo, E; Kanto, J; Lindberg, R; Manner, T; Scheinin, M; Viinamäki, O, 1987) |
| "To investigate the effect of local usage of prilocaine and ıts combination with tramadol on the pain and anxiety levels of patients during nasal packing removal." | 3.96 | Effect of prilocaine and its combination with tramadol on anxiety and pain during nasal packing removal. ( Arslan, E; Tulaci, KG; Tulaci, RG; Yazici, H, 2020) |
| "Some children report significant pain with peripheral intravenous catheter (IV) insertion, despite the appropriate use of topical lidocaine anesthetics." | 3.74 | Predictors of topical anesthetic effectiveness in children. ( Floria-Santos, M; Hanrahan, K; Kleiber, C; McCarthy, AM; Murray, JC; Schutte, DL, 2007) |
| "Pain was assessed by visual analogue scale (VAS) and anxiety levels by the State-Trait Anxiety Inventory (STAI-I and STA-II)." | 2.77 | No effect of perianal application of topical anaesthetic on patient comfort during nonsedated flexible sigmoidoscopy: a randomized, placebo-controlled clinical trial. ( Boyacioglu, S; Cengiz, C; Kuzu, MA; Ozdemir, B; Pampal, HK, 2012) |
| "FNAC-related pain is frequent and correlates with the number of nodules biopsied, age under 25 years, female sex, and anxiety." | 1.39 | Frequency and intensity of pain related to thyroid nodule fine-needle aspiration cytology. ( Azoulay, S; Baudin, E; Berdelou, A; Bidault, S; Borget, I; Chougnet, CN; Dauchy, S; Deandreis, D; Girard, E; Hartl, D; Labro, S; Laurent, S; Leboulleux, S; Lumbroso, J; Mirghani, H; Schlumberger, M; Vielh, P, 2013) |
| "In fact, the nurse coached more, and trends suggested that children coped more with typical care than with EMLA." | 1.30 | Comparative study of distraction versus topical anesthesia for pediatric pain management during immunizations. ( Blount, RL; Cohen, LL; Cohen, RJ; Schaen, ER; Zaff, JF, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.00) | 18.7374 |
| 1990's | 9 (45.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 3 (15.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tulaci, KG | 1 |
| Arslan, E | 1 |
| Tulaci, RG | 1 |
| Yazici, H | 1 |
| Carson, C | 1 |
| Wyllie, M | 1 |
| Cengiz, C | 1 |
| Pampal, HK | 1 |
| Ozdemir, B | 1 |
| Boyacioglu, S | 1 |
| Kuzu, MA | 1 |
| Leboulleux, S | 1 |
| Borget, I | 1 |
| Labro, S | 1 |
| Bidault, S | 1 |
| Vielh, P | 1 |
| Hartl, D | 1 |
| Dauchy, S | 1 |
| Chougnet, CN | 1 |
| Girard, E | 1 |
| Azoulay, S | 1 |
| Mirghani, H | 1 |
| Berdelou, A | 1 |
| Lumbroso, J | 1 |
| Deandreis, D | 1 |
| Baudin, E | 1 |
| Schlumberger, M | 1 |
| Laurent, S | 1 |
| Hee, HI | 1 |
| Goy, RW | 1 |
| Ng, AS | 1 |
| Zempsky, WT | 1 |
| Cravero, JP | 1 |
| Meechan, JG | 1 |
| Ekbom, K | 1 |
| Jakobsson, J | 1 |
| Marcus, C | 1 |
| Kleiber, C | 1 |
| Schutte, DL | 1 |
| McCarthy, AM | 1 |
| Floria-Santos, M | 1 |
| Murray, JC | 1 |
| Hanrahan, K | 1 |
| Gianoutsos, MP | 1 |
| Hunter-Smith, D | 1 |
| Smith, JG | 1 |
| Hogan, D | 1 |
| McEwan, L | 1 |
| Vetter, TR | 1 |
| Lander, J | 1 |
| Hodgins, M | 1 |
| Nazarali, S | 1 |
| McTavish, J | 1 |
| Ouellette, J | 1 |
| Friesen, E | 1 |
| Young, SS | 1 |
| Schwartz, R | 1 |
| Sheridan, MJ | 1 |
| Mjahed, K | 1 |
| Sadraoui, A | 1 |
| Benslama, A | 1 |
| Idali, B | 1 |
| Benaguida, M | 1 |
| Koh, JL | 1 |
| Fanurik, D | 1 |
| Stoner, PD | 1 |
| Schmitz, ML | 1 |
| VonLanthen, M | 1 |
| Choy, L | 1 |
| Collier, J | 1 |
| Watson, AR | 1 |
| Cohen, LL | 1 |
| Blount, RL | 1 |
| Cohen, RJ | 1 |
| Schaen, ER | 1 |
| Zaff, JF | 1 |
| Southwell, GC | 1 |
| Wig, J | 1 |
| Johl, KS | 1 |
| Manner, T | 1 |
| Kanto, J | 1 |
| Iisalo, E | 1 |
| Lindberg, R | 1 |
| Viinamäki, O | 1 |
| Scheinin, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Inhaled 50% Equimolar Nitrous Oxide/Oxygen Gas Premix (Kalinox®) as Compared to Topically Administered 5% Eutectic Mixture of Lidocaine/Prilocaine (EMLA®) in Chronic Leg Ulcer Debridement[NCT02696460] | 21 participants (Actual) | Interventional | 2010-04-30 | Completed | |||
| A Comparison of Amethocaine Creams Versus Liposomal Lidocaine Cream as Pain Reliever Prior to Venipuncture in Children at the Paediatric Emergency Department.[NCT00353002] | 0 participants (Actual) | Interventional | 2006-07-31 | Withdrawn | |||
| A Randomized, Placebo-Controlled Trial to Evaluate Pain and Anxiety During Venipuncture in Pediatric Patients With or Without Pre-treatment by a Topical Anesthetic[NCT00676364] | Phase 4 | 114 participants (Actual) | Interventional | 2003-03-31 | Completed | ||
| Randomized Controlled Trial of IN Midazolam vs IN Dexmedetomidine vs IN Ketamine Evaluating Length of Stay After Medication Administration and Anxiolysis During Minimal Procedures in Pediatric Population in Pediatric Emergency Department[NCT05934669] | Phase 4 | 90 participants (Anticipated) | Interventional | 2024-01-31 | Not yet recruiting | ||
| Topical Analgesia Before Inhalational Anaesthesia: A Retrospective Observational Study[NCT04959409] | 500 participants (Actual) | Observational | 2020-08-01 | Completed | |||
| Understanding Pediatric Symptoms and Other Symptoms[NCT00166231] | 156 participants (Actual) | Observational | 2004-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Participant anxiety was measured by the study participant and the objective observer before (anticipatory), during (venipuncture) and after (recovery) venipuncture using a validated visual analog scale (VAS). The VAS is a validated scale that is used to detect small changes in many types of observations. The scale ranges from 0-100 scores on a scale, and here the higher scores indicate higher anxiety levels. Only the participant's mean venipuncture (during venipuncture) anxiety scores are presented in outcome measure results here. (NCT00676364)
Timeframe: During venipuncture
| Intervention | scores on a scale (Mean) |
|---|---|
| ControI Group Receiving Placebo Cream | 43.1 |
| Investigational Group | 40.5 |
"Pain was measured immediately after venipuncture by the participant using the six-point FACES scale. FACES in not an acronym, but rather a description of a pain scale that uses pictures of faces in various states of pain. The FACES pain scale is a common scale used to measure pain with scores on a scale. The scale we used had six points from zero (0) to five (5) indicating different levels of pain. Lower scores indicate lower levels of pain, and higher scores indicate higher levels of pain." (NCT00676364)
Timeframe: Pain was measured immediately after venipuncture.
| Intervention | scores on a scale (Mean) |
|---|---|
| ControI Group Receiving Placebo Cream | 2.2 |
| Investigational Group Receiving 4% Lidocaine Cream | 2.1 |
13 trials available for prilocaine and Anxiety
| Article | Year |
|---|---|
Improved ejaculatory latency, control and sexual satisfaction when PSD502 is applied topically in men with premature ejaculation: results of a phase III, double-blind, placebo-controlled study.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anesthetics, Local; Anxiety; Coitus; Double-Blind | 2010 |
No effect of perianal application of topical anaesthetic on patient comfort during nonsedated flexible sigmoidoscopy: a randomized, placebo-controlled clinical trial.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anesthesia, Local; Anxiety; Female; Humans; Lidoca | 2012 |
Effective reduction of anxiety and pain during venous cannulation in children: a comparison of analgesic efficacy conferred by nitrous oxide, EMLA and combination.
Topics: Adolescent; Analysis of Variance; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, Local | 2003 |
Nitrous oxide inhalation is a safe and effective way to facilitate procedures in paediatric outpatient departments.
Topics: Adolescent; Analgesics; Anesthetics, Inhalation; Anxiety; Catheterization; Child; Female; Humans; Li | 2005 |
Oral premedication for local anesthesia in plastic surgery: prospective, randomized, blind comparison of lorazepam and temazepam.
Topics: Administration, Oral; Aged; Aged, 80 and over; Anesthesia, Local; Anxiety; Double-Blind Method; Epin | 1994 |
A comparison of EMLA cream versus nitrous oxide for pediatric venous cannulation.
Topics: Administration, Topical; Analgesics, Non-Narcotic; Anesthetics, Local; Anxiety; Catheterization, Per | 1995 |
Determinants of success and failure of EMLA.
Topics: Administration, Topical; Adolescent; Adolescent Behavior; Anesthetics; Anxiety; Bandages; Catheteriz | 1996 |
Determinants of success and failure of EMLA.
Topics: Administration, Topical; Adolescent; Adolescent Behavior; Anesthetics; Anxiety; Bandages; Catheteriz | 1996 |
Determinants of success and failure of EMLA.
Topics: Administration, Topical; Adolescent; Adolescent Behavior; Anesthetics; Anxiety; Bandages; Catheteriz | 1996 |
Determinants of success and failure of EMLA.
Topics: Administration, Topical; Adolescent; Adolescent Behavior; Anesthetics; Anxiety; Bandages; Catheteriz | 1996 |
EMLA cream as a topical anesthetic before office phlebotomy in children.
Topics: Adolescent; Ambulatory Care; Anesthetics, Local; Anxiety; Child; Child, Preschool; Double-Blind Meth | 1996 |
[Combination of Emla cream and nitrous oxide for venous cannulation in children].
Topics: Administration, Cutaneous; Anesthesia, Inhalation; Anesthesia, Local; Anesthetics, Combined; Anesthe | 1997 |
Efficacy of parental application of eutectic mixture of local anesthetics for intravenous insertion.
Topics: Adolescent; Anesthesia, Local; Anesthetics, Local; Anxiety; Child; Child, Preschool; Female; Humans; | 1999 |
Comparison of lignocaine-prilocaine cream and amethocaine gel for local analgesia before venepuncture in children.
Topics: Adolescent; Analgesia; Anesthetics, Combined; Anesthetics, Local; Anxiety; Child; Child, Preschool; | 1999 |
Our experience with EMLA Cream (for painless venous cannulation in children).
Topics: Anesthetics, Local; Anxiety; Catheterization, Peripheral; Child; Child, Preschool; Drug Combinations | 1990 |
Reduction of pain at venous cannulation in children with a eutectic mixture of lidocaine and prilocaine (EMLA cream): comparison with placebo cream and no local premedication.
Topics: Administration, Cutaneous; Anesthetics, Local; Anxiety; Catecholamines; Catheterization, Peripheral; | 1987 |
7 other studies available for prilocaine and Anxiety
| Article | Year |
|---|---|
Effect of prilocaine and its combination with tramadol on anxiety and pain during nasal packing removal.
Topics: Anxiety; Humans; Pain; Prilocaine; Rhinoplasty; Tramadol | 2020 |
Frequency and intensity of pain related to thyroid nodule fine-needle aspiration cytology.
Topics: Acetaminophen; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Ambulatory Care Facilities; | 2013 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Differences between men and women regarding attitudes toward dental local anesthesia among junior students at a United Kingdom dental school.
Topics: Anesthesia, Dental; Anesthesia, Local; Anesthesiology; Anesthetics, Local; Anxiety; Attitude to Heal | 2005 |
Predictors of topical anesthetic effectiveness in children.
Topics: Administration, Topical; Age Factors; Anesthetics, Local; Anxiety; Catheterization, Peripheral; Chil | 2007 |
Comparative study of distraction versus topical anesthesia for pediatric pain management during immunizations.
Topics: Anesthetics, Local; Anxiety; Child; Child Behavior; Female; Humans; Immunization; Lidocaine; Lidocai | 1999 |
Physiological responses under dental sedation and anaesthesia.
Topics: Analgesia; Anesthesia, Dental; Anxiety; Atropine; Blood Pressure; Diazepam; Epinephrine; Heart Rate; | 1976 |