prilocaine and Anesthesia Related Hyperthermia

prilocaine has been researched along with Anesthesia Related Hyperthermia in 2 studies

Prilocaine: A local anesthetic that is similar pharmacologically to LIDOCAINE. Currently, it is used most often for infiltration anesthesia in dentistry.
prilocaine : An amino acid amide in which N-propyl-DL-alanine and 2-methylaniline have combined to form the amide bond; used as a local anaesthetic.

Research

Studies (2)

Authors

Clinical Trials (2)

Trial Overview

Trial Outcomes

Bromage Motor Block Level at End of Surgery

Bromage scale (1 = no motor block; 2 = hip blocked; 3 = hip and knee blocked; and 4 = hip, knee, and ankle blocked) was used to evaluate the motor block every 15 min after spinal anaesthesia (T0) and until the end of surgery. (NCT03036384)
Timeframe: Until complete release of motor block (average 4 hours)

Motor Block Duration

Bromage scale (1 = no motor block; 2 = hip blocked; 3 = hip and knee blocked; and 4 = hip, knee, and ankle blocked) was used to evaluate the motor block every 15 minutes after spinal anaesthesia (T0) and until the end of surgery. Duration was defined from the time of the spinal injection until Bromage scale = 1. (NCT03036384)
Timeframe: Until complete release of motor block (Bromage scale = 1; average 4 hours)

Newborn Methemoglobinemia (MetHb)

Newborn Methemoglobinemia (MetHb) will be assessed at delivery by cordal blood sample, as a routine control, and expressed as a percentage of total hemoglobinemia. (NCT03036384)
Timeframe: average 1 hour

Number of Participants Needing Vasopressors

"Arterial blood pressure will be measured at every 2.5 minute during surgery, then at every 20 minutes in the PACU (Post Anesthesia Care Unit). Vasopressors were given for patients with low blood pressure.~A low blood pressure is defined as a blood pressure lower than 20% or more than the basal blood pressure (Systolic blood pressure before spinal anesthesia)." (NCT03036384)
Timeframe: during surgery (average 1 hour)

Number of Participants With Dizziness

All parturients will be questioned for dizziness (yes or no) (NCT03036384)
Timeframe: Up to 24 hours after surgery

Number of Participants With Nausea or Vomiting

from 15 minutes after spinal anesthesia and every 4 hours for 24 hours (score 0=no symptoms; 1=symptoms with no treatment necessary; 2=symptoms present and treated) (NCT03036384)
Timeframe: up to 24 hours after surgery

Number of Participants With Pruritus

from 15 minutes after spinal anesthesia and every 4 hours for 24 hours (score 0=no symptoms; 1=symptoms with no treatment necessary; 2=symptoms present and treated) (NCT03036384)
Timeframe: Up to 24 hours after surgery

Number of Participants With Transient Neurologic Symptoms (TNS)

TNS are defined as pain and/or dysesthesia occurred after complete release of sensory block at the gluteal level, at the thighs and at the legs. At Day 0, Day 1, Day 3 and Day 5 (NCT03036384)
Timeframe: up to 5 Days

Number of Participants With Urinary Retention

All parturients will be questioned for urinary retention (yes or no) (NCT03036384)
Timeframe: Up to 24 hours after surgery

Number of Satisfied Participants

Maternal satisfaction (yes or no) will be assessed 1 hour after surgery in the PACU (Post Anesthesia Care Unit) (NCT03036384)
Timeframe: up to 1 hour after surgery

Sensitive Block at End of Surgery

Level of Sensory block assessed as loss of sensation to cold, every 2 minutes after spinal anesthesia during 15 minutes, then every 5 minutes until the end of surgery, thereafter, once 30 minutes until total regression of sensory block (T12-S1). For this study, dermatome levels are depicted on a scale ranging from 1 to 18. (1 to 12 = T1-T12 thoracic levels; 13 to 17 = L1-L5 lumbar levels; 18 = S1 sacral level) (NCT03036384)
Timeframe: Until complete release of sensory block (T12-S1) (average 4 hours)

Sensitive Block Duration

Level of Sensory block assessed as loss of sensation to cold, every 2 minutes after spinal anesthesia during 15 minutes, then every 5 minutes until the end of surgery, thereafter, once 30 minutes until total regression of sensory block (T12-S1). (NCT03036384)
Timeframe: Until complete release of sensory block (T12-S1) (average 4 hours)

Newborn Apgar Score

"Newborn Apgar score assessed at 1, 5, 10 minutes after baby extraction. The Apgar score is determined by evaluating the newborn baby on five simple criteria on a scale from 0 to 2, then summing up the five values thus obtained. The overall resulting score ranges from 0 to 10 ( 0-3 : severely depressed, 4-6 : Moderately depressed and 7-10 : Excellent condition).~The five criteria are summarized using words chosen to form an abbreviation (Appearance, Pulse, Grimace, Activity, Respiration)." (NCT03036384)
Timeframe: up to 10 minutes after baby extraction

Success of Anesthesia

The nerve blockade will be considered as success when a bilateral T4 level will reach in 15 minutes after intrathecal injection without additional epidural injection needed within 45 minutes peri-operative ; no pain at the skin incision, no pain during 45 minutes after the skin incision (NCT03036384)
Timeframe: during surgery (average 1 hour)

Other Studies

2 other studies available for prilocaine and Anesthesia Related Hyperthermia