prilocaine has been researched along with Anemia in 5 studies
Prilocaine: A local anesthetic that is similar pharmacologically to LIDOCAINE. Currently, it is used most often for infiltration anesthesia in dentistry.
prilocaine : An amino acid amide in which N-propyl-DL-alanine and 2-methylaniline have combined to form the amide bond; used as a local anaesthetic.
Anemia: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It has not yet been clarified whether prilocaine-induced methemoglobinemia is a problem in patients with chronic anemia." | 7.67 | [Supraclavicular plexus blockade using prilocaine in patients with chronic anemia]. ( Viell, B; Wald-Oboussier, G, 1989) |
| "It has not yet been clarified whether prilocaine-induced methemoglobinemia is a problem in patients with chronic anemia." | 3.67 | [Supraclavicular plexus blockade using prilocaine in patients with chronic anemia]. ( Viell, B; Wald-Oboussier, G, 1989) |
| "Pain was assessed using a visual analogue scale, a verbal descriptive scale and a direct comparison between paired treatments." | 2.67 | Pain after subcutaneous injection of recombinant human erythropoietin: does Emla cream help? ( Coulthard, MG; Hardy, SP; Hughes, C; Matthews, JN; Morris, KP, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guay, J | 1 |
| Morris, KP | 1 |
| Hughes, C | 1 |
| Hardy, SP | 1 |
| Matthews, JN | 1 |
| Coulthard, MG | 1 |
| Hahn, J | 1 |
| Wald-Oboussier, G | 1 |
| Viell, B | 1 |
| Dudley, AG | 1 |
| Conrad, LL | 1 |
| Markham, SM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Methemoglobin Levels in Generally Anesthetized Pediatric Dental Patients Receiving Prilocaine Versus Lidocaine[NCT01402869] | 91 participants (Actual) | Interventional | 2011-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Change in percentage of methemoglobin in blood from baseline level to peak level (NCT01402869)
Timeframe: From administration of local anesthetic or start of restorative procedures to time at which maximum methemoglobin blood level was documented during dental treatment for an average of 2 hours
| Intervention | percentage of methemoglobin in blood (Mean) |
|---|---|
| Prilocaine | 2.73 |
| Lidocaine | 0.78 |
| No Local Anesthetic | 0.76 |
The maximum percentage of methemoglobin in blood (NCT01402869)
Timeframe: Measured at 10 second intervals during dental treatment for an average of 2 hours
| Intervention | percentage of methemoglobin in blood (Mean) |
|---|---|
| Prilocaine | 3.55 |
| Lidocaine | 1.63 |
| No Local Anesthetic | 1.60 |
The length of time between the administration of local anesthetic (Prilocaine and Lidocaine Groups) or start of restorative dental procedures (No local anesthetic Group) and the time at which the maximum methemoglobin blood level is observed. (NCT01402869)
Timeframe: Measured at 10 second intervals during dental treatment for an average of 2 hours
| Intervention | minutes (Mean) |
|---|---|
| Prilocaine | 62.73 |
| Lidocaine | 57.50 |
| No Local Anesthetic | 29.50 |
1 review available for prilocaine and Anemia
| Article | Year |
|---|---|
Methemoglobinemia related to local anesthetics: a summary of 242 episodes.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anemia; Anesthetics, Local; Benzocaine; Chi | 2009 |
1 trial available for prilocaine and Anemia
| Article | Year |
|---|---|
Pain after subcutaneous injection of recombinant human erythropoietin: does Emla cream help?
Topics: Adult; Aged; Anemia; Anesthetics, Local; Double-Blind Method; Drug Combinations; Erythropoietin; Fem | 1994 |
3 other studies available for prilocaine and Anemia
| Article | Year |
|---|---|
[Comments on the paper by G. Wald-Oboussier and B. Veill. Supraclavicular plexus blockade using prilocaine in patients with chronic anemia].
Topics: Anemia; Cervical Plexus; Chronic Disease; Humans; Methemoglobinemia; Nerve Block; Prilocaine | 1990 |
[Supraclavicular plexus blockade using prilocaine in patients with chronic anemia].
Topics: Aged; Anemia; Brachial Plexus; Chronic Disease; Female; Humans; Kidney Failure, Chronic; Methemoglob | 1989 |
Continuous intrapartum lumbar epidural block: a comparative study employing propitocaine 2 percent, lidocaine 1.5 percent with epinephrine, and 1.5 percent lidocaine.
Topics: Anemia; Anesthesia, Conduction; Anesthesia, Epidural; Anesthesia, Obstetrical; Epinephrine; Female; | 1971 |