Page last updated: 2024-11-03

prilocaine and Anaphylaxis

prilocaine has been researched along with Anaphylaxis in 8 studies

Prilocaine: A local anesthetic that is similar pharmacologically to LIDOCAINE. Currently, it is used most often for infiltration anesthesia in dentistry.
prilocaine : An amino acid amide in which N-propyl-DL-alanine and 2-methylaniline have combined to form the amide bond; used as a local anaesthetic.

Anaphylaxis: An acute hypersensitivity reaction due to exposure to a previously encountered ANTIGEN. The reaction may include rapidly progressing URTICARIA, respiratory distress, vascular collapse, systemic SHOCK, and death.

Research Excerpts

ExcerptRelevanceReference
"In 87 of the 90 patients with suspected anaphylactoid reactions to local anesthetic agents, negative skin reactions to at least one of the agents allowed intrabuccal challenge and subsequent recommendation of an agent for future use."1.29Skin testing after anaphylactoid reactions to dental local anesthetics. A comparison with controls. ( Challacombe, SJ; Hodgson, TA; Shirlaw, PJ, 1993)
"A case of anaphylactoid reaction with late onset to prilocaine and a positive intracutaneous test is reported."1.26Hypersensitivity to prilocaine. ( Göransson, K, 1976)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's5 (62.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kajimoto, Y1
Rosenberg, ME1
Kyttä, J1
Randell, T1
Tuominen, M1
Reunala, T1
Rosenberg, PH1
Bosco, DA1
Haas, DA1
Young, ER1
Harrop, KL1
Hodgson, TA1
Shirlaw, PJ1
Challacombe, SJ1
Russell, SC1
Doyle, E1
Göransson, K1
Fulcher, DA1
Katelaris, CH1
Ruiz, K1
Stevens, JD1
Train, JJ1
Watkins, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Ethyl Chloride Topical Anesthesia Application on the Pain Perception During Intra-oral Injections in Children in Comparison to Benzocaine Gel- a Single-blinded Randomized Controlled Trial.[NCT06011005]42 participants (Anticipated)Interventional2023-09-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for prilocaine and Anaphylaxis

ArticleYear
A risk-benefit assessment of topical percutaneous local anaesthetics in children.
    Drug safety, 1997, Volume: 16, Issue:4

    Topics: Administration, Cutaneous; Administration, Topical; Anaphylaxis; Anesthetics, Combined; Anesthetics,

1997

Trials

1 trial available for prilocaine and Anaphylaxis

ArticleYear
Anaphylactoid skin reactions after intravenous regional anaesthesia using 0.5% prilocaine with or without preservative--a double-blind study.
    Acta anaesthesiologica Scandinavica, 1995, Volume: 39, Issue:6

    Topics: Adult; Anaphylaxis; Anesthesia, Conduction; Anesthesia, Intravenous; Anesthetics, Local; Double-Blin

1995

Other Studies

6 other studies available for prilocaine and Anaphylaxis

ArticleYear
An anaphylactoid reaction following local anesthesia: a case report.
    Anesthesia & pain control in dentistry, 1993,Spring, Volume: 2, Issue:2

    Topics: Adult; Anaphylaxis; Anesthesia, Dental; Diagnosis, Differential; Drug Hypersensitivity; Female; Huma

1993
Skin testing after anaphylactoid reactions to dental local anesthetics. A comparison with controls.
    Oral surgery, oral medicine, and oral pathology, 1993, Volume: 75, Issue:6

    Topics: Adolescent; Adult; Aged; Anaphylaxis; Anesthesia, Dental; Anesthetics, Local; Chi-Square Distributio

1993
Hypersensitivity to prilocaine.
    Dermatologica, 1976, Volume: 152, Issue:3

    Topics: Anaphylaxis; Drug Hypersensitivity; Humans; Male; Middle Aged; Prilocaine

1976
Anaphylactoid reactions to local anaesthetics despite IgE deficiency: a case report.
    Asian Pacific journal of allergy and immunology, 1990, Volume: 8, Issue:2

    Topics: Adult; Anaphylaxis; Anesthetics, Local; Female; Histamine; Humans; Immunoglobulin E; Injections, Int

1990
Anaphylactoid reactions to prilocaine.
    Anaesthesia, 1988, Volume: 43, Issue:3

    Topics: Aged; Aged, 80 and over; Anaphylaxis; Anesthesia, Intravenous; Drug Hypersensitivity; Female; Humans

1988
Anaphylactoid reactions to prilocaine.
    Anaesthesia, 1987, Volume: 42, Issue:10

    Topics: Aged; Aged, 80 and over; Anaphylaxis; Anesthesia, Intravenous; Anesthesia, Local; Female; Humans; Mi

1987