prilocaine has been researched along with Amputation, Traumatic in 1 studies
Prilocaine: A local anesthetic that is similar pharmacologically to LIDOCAINE. Currently, it is used most often for infiltration anesthesia in dentistry.
prilocaine : An amino acid amide in which N-propyl-DL-alanine and 2-methylaniline have combined to form the amide bond; used as a local anaesthetic.
Amputation, Traumatic: Loss of a limb or other bodily appendage by accidental injury.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shi, LL | 1 |
| Sargen, MR | 1 |
| Chen, SC | 1 |
| Arbiser, JL | 1 |
| Pollack, BP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized, Single Center, Masked Study Comparing the Efficacy of Botulinum Toxin Type A Injection After Topical Anesthesia Versus Petrolatum Ointment[NCT03799484] | Phase 4 | 14 participants (Actual) | Interventional | 2019-01-04 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Loss of Botulinum Toxin Type A effect is defined as return of baseline frontalis muscle function (function prior to injection) as indicated by eyebrow excursion measurement within 2 millimeters of baseline value. (NCT03799484)
Timeframe: week 16
| Intervention | weeks (Mean) |
|---|---|
| Topical Anesthesia | 14.2857 |
| Petrolatum | 15.2857 |
(NCT03799484)
Timeframe: week 16
| Intervention | millimeters (Mean) |
|---|---|
| Topical Anesthesia | 8.21 |
| Petrolatum | 8.07 |
Participants will be asked to raise the brows, and the excursion of the brow from resting position to maximum elevation will be measured in millimeters. (NCT03799484)
Timeframe: Baseline
| Intervention | millimeters (Mean) |
|---|---|
| Topical Anesthesia | 10.57 |
| Petrolatum | 10.57 |
Participants will be asked to raise the brows, and the excursion of the brow from resting position to maximum elevation will be measured in millimeters. (NCT03799484)
Timeframe: Week 2
| Intervention | millimeters (Mean) |
|---|---|
| Topical Anesthesia | 3.46 |
| Petrolatum | 3.43 |
Participants will be asked to raise the brows, and the excursion of the brow from resting position to maximum elevation will be measured in millimeters. (NCT03799484)
Timeframe: Week 6
| Intervention | millimeters (Mean) |
|---|---|
| Topical Anesthesia | 5.96 |
| Petrolatum | 5.68 |
Participants will be asked if there is a noticeable difference between the 2 sides of their face. (NCT03799484)
Timeframe: Week 16
| Intervention | Participants (Count of Participants) |
|---|---|
| All Participants | 0 |
Participants will be asked if there is a noticeable difference between the 2 sides of their face. (NCT03799484)
Timeframe: Week 2
| Intervention | Participants (Count of Participants) |
|---|---|
| All Participants | 3 |
Participants will be asked if there is a noticeable difference between the 2 sides of their face. (NCT03799484)
Timeframe: Week 6
| Intervention | Participants (Count of Participants) |
|---|---|
| All Participants | 2 |
A visual analogue scale will be used to assess pain. The scale ranges from 0 (no pain) to 10 (the worse pain possible), with lower scores indicating a better outcome. (NCT03799484)
Timeframe: Immediately after botox injection
| Intervention | units on a scale (Mean) |
|---|---|
| Topical Anesthesia | 2.43 |
| Petrolatum | 3.96 |
1 other study available for prilocaine and Amputation, Traumatic
| Article | Year |
|---|---|
Effective local anesthesia for onabotulinumtoxin A injections to treat hyperhidrosis associated with traumatic amputation.
Topics: Acetylcholine Release Inhibitors; Administration, Cutaneous; Amputation Stumps; Amputation, Traumati | 2016 |