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pridinol and Neuroleptic Malignant Syndrome

pridinol has been researched along with Neuroleptic Malignant Syndrome in 2 studies

pridinol: antispasmodic & muscle relaxant; RN given refers to parent cpd; structure in Merck Index, 9th ed, #7539
pridinol : A piperidine substituted at position 1 by a 3-hydroxy-3,3-diphenylpropyl group.

Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Susman, VL1
Addonizio, G1
Giordani, L1
Amore, M1
Montanari, A1
Berlinzani, L1
Gentili, C1

Other Studies

2 other studies available for pridinol and Neuroleptic Malignant Syndrome

ArticleYear
Assessing treatment of neuroleptic malignant syndrome.
    The American journal of psychiatry, 1986, Volume: 143, Issue:1

    Topics: Amantadine; Bromocriptine; Cortisone; Drug Therapy, Combination; Humans; Neuroleptic Malignant Syndr

1986
Pridinolum mesylate and neuroleptic malignant syndrome.
    The American journal of psychiatry, 1985, Volume: 142, Issue:3

    Topics: Adult; Basal Ganglia Diseases; Delusions; Haloperidol; Humans; Male; Neuroleptic Malignant Syndrome;

1985