pregnenolone sulfate has been researched along with Schizophrenia in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chodounska, H; Chvojkova, M; Holubova, K; Hrcka Krausova, B; Kudova, E; Vales, K; Vyklicky, L; Vyklicky, V | 1 |
| Meltzer, HY; Rajagopal, L; Soni, D | 1 |
| Chang, CC; Lee, J; Sze, Y; Wong, P; Zhang, X | 1 |
| Bradford, DW; Buchanan, RW; Dunn, L; Hamer, RM; Keefe, RS; Kilts, JD; Leimone, LA; Lieberman, JA; Marx, CE; Morrow, AL; Naylor, JC; Payne, VM; Porcu, P; Savitz, AJ; Shampine, LJ; Strauss, JL | 1 |
1 trial(s) available for pregnenolone sulfate and Schizophrenia
| Article | Year |
|---|---|
Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophrenia.
Topics: Adult; Aged; Brain; Brain Chemistry; Cognition Disorders; Double-Blind Method; Female; Humans; Male; Memory Disorders; Middle Aged; Neuropsychological Tests; Nootropic Agents; Pilot Projects; Placebos; Pregnanolone; Pregnenolone; Schizophrenia; Treatment Outcome; Up-Regulation | 2009 |
3 other study(ies) available for pregnenolone sulfate and Schizophrenia
| Article | Year |
|---|---|
Pitfalls of NMDA Receptor Modulation by Neuroactive Steroids. The Effect of Positive and Negative Modulation of NMDA Receptors in an Animal Model of Schizophrenia.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, Animal; Dizocilpine Maleate; Elevated Plus Maze Test; HEK293 Cells; Humans; Male; Pregnenolone; Rats, Long-Evans; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Schizophrenia; Steroids | 2021 |
Neurosteroid pregnenolone sulfate, alone, and as augmentation of lurasidone or tandospirone, rescues phencyclidine-induced deficits in cognitive function and social interaction.
Topics: Animals; Antipsychotic Agents; Cognition; Drug Therapy, Combination; Interpersonal Relations; Isoindoles; Lurasidone Hydrochloride; Male; Mice, Inbred C57BL; Neurotransmitter Agents; Phencyclidine; Piperazines; Pregnenolone; Pyrimidines; Random Allocation; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology | 2018 |
Pregnenolone sulfate normalizes schizophrenia-like behaviors in dopamine transporter knockout mice through the AKT/GSK3β pathway.
Topics: Animals; Behavior, Animal; Blotting, Western; Dopamine Plasma Membrane Transport Proteins; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Male; Mice; Mice, Knockout; Pregnenolone; Proto-Oncogene Proteins c-akt; Schizophrenia | 2015 |