pregnenolone carbonitrile has been researched along with Pregnancy in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (40.00) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujiwara, R; Hirashima, R; Itoh, T; Kobayashi, Y; Michimae, H; Sasaki, A; Takemoto, H; Tukey, RH | 1 |
| Gahir, SS; Piquette-Miller, M | 1 |
| Blumberg, B; Casey, SC | 1 |
| Doi, K; Ejiri, N; Katayama, K | 1 |
| Baba, Y; Doi, K; Ejiri, N; Katayama, K; Kiyosawa, N | 2 |
| Mannering, GJ; Robbins, MS | 1 |
| Cai, MX; Conney, AH; Fu, J; Kosh, JW; Xu, S; Zhu, BT | 1 |
| Selye, H; Taché, J; Taché, Y | 1 |
| Buhler, DR; McCrary, JA; Novak, RF; Primiano, T; Springer, DL; Zangar, RC | 1 |
| Bonfils, C; Daujat, M; Fabre, G; Fabre, I; Maurel, P; Pichard, L; Pineau, T | 1 |
| Cresteil, T; Marie, S | 1 |
| Hulla, JE; Juchau, MR | 1 |
| Mathis, JM; Prough, RA; Simpson, ER | 1 |
| Juchau, MR; Namkung, MJ; Nelson, SD; Porubek, DJ | 1 |
15 other study(ies) available for pregnenolone carbonitrile and Pregnancy
| Article | Year |
|---|---|
Induction of the UDP-Glucuronosyltransferase 1A1 during the Perinatal Period Can Cause Neurodevelopmental Toxicity.
Topics: Animals; Animals, Newborn; Brain; Carbamazepine; Cell Movement; Enzyme Induction; Female; Gene Expression Regulation, Developmental; Genes, Developmental; Glucuronosyltransferase; Humans; Mice, Inbred C57BL; Mice, Transgenic; Milk, Human; Neurodevelopmental Disorders; Phenytoin; Pregnancy; Pregnenolone Carbonitrile; Prenatal Exposure Delayed Effects; RNA, Messenger; Rotarod Performance Test; Thyroxine | 2016 |
Gestational and pregnane X receptor-mediated regulation of placental ATP-binding cassette drug transporters in mice.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Female; Gene Expression Regulation, Developmental; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Multidrug Resistance-Associated Proteins; Organ Specificity; Placenta; Pregnancy; Pregnancy Proteins; Pregnane X Receptor; Pregnenolone Carbonitrile; Protein Isoforms; Receptors, Steroid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2011 |
The steroid and xenobiotic receptor negatively regulates B-1 cell development in the fetal liver.
Topics: Animals; B-Lymphocyte Subsets; Cell Count; Cell Proliferation; Female; Fetal Organ Maturity; Gene Expression Profiling; Gene Expression Regulation, Developmental; Liver; Male; Maternal-Fetal Exchange; Mice; Mice, Knockout; NF-kappa B; Peritoneal Cavity; Precursor Cells, B-Lymphoid; Pregnancy; Pregnane X Receptor; Pregnenolone Carbonitrile; Receptors, Steroid; Transcription, Genetic | 2012 |
Induction of CYP3A1 by dexamethasone and pregnenolone-16alpha-carbonitrile in pregnant rat and fetal livers and placenta.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Cytochrome P-450 CYP3A; Dexamethasone; Enzyme Activators; Enzyme Induction; Female; Fetus; Hepatocytes; Immunohistochemistry; Liver; Placenta; Pregnancy; Pregnancy, Animal; Pregnenolone Carbonitrile; Rats; Rats, Inbred F344 | 2003 |
Microarray analysis on CYPs expression in pregnant rats after treatment with pregnenolone-16alpha-carbonitrile and phenobarbital.
Topics: Animals; Constitutive Androstane Receptor; Cytochrome P-450 Enzyme System; DNA Primers; Enzyme Induction; Female; Fetus; Injections, Intraperitoneal; Isoenzymes; Liver; Phenobarbital; Placenta; Pregnancy; Pregnenolone Carbonitrile; Protein Array Analysis; Rats; Rats, Inbred F344; RNA, Messenger | 2005 |
Microarray analysis on Phase II drug metabolizing enzymes expression in pregnant rats after treatment with pregnenolone-16alpha-carbonitrile or phenobarbital.
Topics: Animals; Enzyme Induction; Female; Glucuronosyltransferase; Glutathione Transferase; Injections, Intraperitoneal; Isoenzymes; Liver; Metabolic Detoxication, Phase II; Oligonucleotide Array Sequence Analysis; Phenobarbital; Placenta; Pregnancy; Pregnenolone Carbonitrile; Rats; Rats, Inbred F344 | 2005 |
Effects of the interferon inducing agents tilorone and polyriboinosinic acid . polyribocytidylic acid (poly IC) on the hepatic monooxygenase systems of pregnant and fetal rats.
Topics: Aminopyrine N-Demethylase; Animals; Benzopyrene Hydroxylase; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Female; Fetus; Fluorenes; Liver; Maternal-Fetal Exchange; Methylcholanthrene; Oxygenases; Phenobarbital; Poly I-C; Pregnancy; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Tilorone | 1984 |
Strong inhibition of estrone-3-sulfatase activity by pregnenolone 16alpha-carbonitrile but not by several analogs lacking a 16alpha-nitrile group.
Topics: Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Microsomes, Liver; Models, Molecular; Molecular Conformation; Nitriles; Placenta; Pregnancy; Pregnenolone Carbonitrile; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Static Electricity; Structure-Activity Relationship; Subcellular Fractions; Sulfatases | 2000 |
3Beta-hydroxy-20-oxo-pregn-5-ene-16 alpha-carbonitrile, a potent catatoxic steroid devoid of an abortifacient effect.
Topics: Abortifacient Agents; Animals; Castration; Estrone; Female; Hypophysectomy; Pregnancy; Pregnancy, Animal; Pregnenolone Carbonitrile; Progesterone; Rats | 1975 |
Changes in adult metabolism of aflatoxin B1 in rats neonatally exposed to diethylstilbestrol. Alterations in alpha-class glutathione S-transferases.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Animals; Biotransformation; Blotting, Western; Diethylstilbestrol; DNA; Enzyme Induction; Female; Glutathione Transferase; Liver; Male; Phenobarbital; Pregnancy; Pregnenolone Carbonitrile; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley | 1992 |
Induction protocols for cytochromes P450IIIA in vivo and in primary cultures of animal and human hepatocytes.
Topics: Animals; Anti-Bacterial Agents; Cells, Cultured; Culture Techniques; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Erythromycin; Female; Fetus; Humans; Liver; Male; Pregnancy; Pregnenolone Carbonitrile; Rabbits; Rats; Rats, Inbred Strains; Rifampin; Sex Characteristics; Troleandomycin | 1991 |
Phenobarbital-inducible gene expression in developing rat liver: relationship to hepatocyte function.
Topics: Animals; Blotting, Northern; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Gene Expression Regulation, Enzymologic; Glucuronosyltransferase; Isoenzymes; Liver; Male; Phenobarbital; Polycyclic Compounds; Pregnancy; Pregnenolone Carbonitrile; Rats; RNA | 1989 |
Occurrence and inducibility of cytochrome P450IIIA in maternal and fetal rats during prenatal development.
Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Embryonic and Fetal Development; Enzyme Induction; Enzyme-Linked Immunosorbent Assay; Female; Gestational Age; Immunoblotting; Male; Microsomes, Liver; Pregnancy; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Substrate Specificity | 1989 |
Synergistic induction of monooxygenase activity by glucocorticoids and polycyclic aromatic hydrocarbons in human fetal hepatocytes in primary monolayer culture.
Topics: Aryl Hydrocarbon Hydroxylases; Benz(a)Anthracenes; Benzo(a)pyrene; Cells, Cultured; Coumarins; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Induction; Female; Fetus; Glucocorticoids; Humans; Hydrocortisone; Hydroxylation; Kinetics; Liver; Oxygenases; Polycyclic Compounds; Pregnancy; Pregnenolone Carbonitrile; Receptors, Glucocorticoid | 1986 |
Regulation of aromatic oxidation of estradiol-17 beta in maternal hepatic, fetal hepatic and placental tissues: comparative effects of a series of inducing agents.
Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 CYP1A1; Estradiol; Ethanol; Female; Liver; Male; Methylcholanthrene; Phenobarbital; Placenta; Polychlorinated Dibenzodioxins; Pregnancy; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Safrole; Steroid Hydroxylases | 1985 |