pregnenolone carbonitrile has been researched along with Aging in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (60.00) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujiwara, R; Hirashima, R; Itoh, T; Kutsuno, Y; Michimae, H; Sakamoto, M; Tukey, RH; Ushikubo, H | 1 |
| Etzrodt, J; Glöckner, R; Lupp, A; Müller, D | 1 |
| Guo, GL; Johnson, DR; Klaassen, CD | 1 |
| Cheung, C; Fukamachi, K; Gonzalez, FJ; Krausz, KW; Yu, AM | 1 |
| Förlin, L | 1 |
| Fujita, S; Funae, Y; Imaoka, S; Kazusaka, A; Maeda, Y; Masuda, M; Morita, K | 1 |
| Dunn, RT; Gleason, BA; Hartley, DP; Klaassen, CD | 1 |
| Kourounakis, P; Selye, H; Taché, Y | 1 |
| Beer, FJ | 1 |
| Klaassen, CD; Stacey, NH | 1 |
| Garg, BD; Kourounakis, P; Tuchweber, B | 1 |
| Klaassen, CD | 2 |
| Hadjipetrou-Kourounakis, L; Kourounakis, P; Yiangou, M | 1 |
| Dannan, GA; Guengerich, FP; Nelson, SD; Porubek, DJ; Waxman, DJ | 1 |
1 review(s) available for pregnenolone carbonitrile and Aging
| Article | Year |
|---|---|
Catatoxic steroids.
Topics: Aging; Animals; Drug Antagonism; Female; Male; Pharmaceutical Preparations; Pregnenolone Carbonitrile; Rats; Sex Factors; Steroids; Tissue Distribution | 1977 |
14 other study(ies) available for pregnenolone carbonitrile and Aging
| Article | Year |
|---|---|
Expression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse Brain.
Topics: Adult; Aging; Animals; Brain Chemistry; Carbamazepine; Estradiol; Female; Glucuronides; Humans; Isoenzymes; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microsomes; Microsomes, Liver; Middle Aged; Monosaccharide Transport Proteins; Pregnenolone Carbonitrile; Serotonin | 2015 |
Precision-cut liver slices from rats of different ages: basal cytochrome P450-dependent monooxygenase activities and inducibility.
Topics: Aging; Animals; Anti-Inflammatory Agents; beta-Naphthoflavone; Coumarins; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Dexamethasone; Dimethyl Sulfoxide; Enzyme Induction; Enzyme Inhibitors; Hydroxylation; Liver; Male; Mixed Function Oxygenases; Organ Culture Techniques; Oxazines; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Wistar; Testosterone; Time Factors | 2008 |
Expression of rat Multidrug Resistance Protein 2 (Mrp2) in male and female rats during normal and pregnenolone-16alpha-carbonitrile (PCN)-induced postnatal ontogeny.
Topics: Aging; Animals; Animals, Newborn; Female; Liver; Male; Mitochondrial Proteins; Organic Anion Transporters; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Ribosomal Proteins; RNA; Saccharomyces cerevisiae Proteins | 2002 |
Potential role for human cytochrome P450 3A4 in estradiol homeostasis.
Topics: Aging; Animals; Aryl Hydrocarbon Hydroxylases; Caseins; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Estradiol; Female; Gene Expression; Homeostasis; Humans; Lactation; Liver; Male; Mammary Glands, Animal; Mice; Mice, Transgenic; Milk Proteins; Oxidoreductases, N-Demethylating; Phenotype; Pregnenolone Carbonitrile; Sex Factors; Transgenes | 2005 |
Effects of clophen A50, 3-methylcholanthrene, pregnenolone-16 alpha-carbonitrile, and phenobarbital on the hepatic microsomal cytochrome P-450-dependent monooxygenase system in rainbow trout, Salmo gairdneri, of different age and sex.
Topics: Aging; Animals; Benzopyrene Hydroxylase; Cytochrome P-450 Enzyme System; Female; Male; Methylcholanthrene; Microsomes, Liver; Nitroanisole O-Demethylase; Oxidoreductases; Phenobarbital; Polychlorinated Biphenyls; Pregnenolone Carbonitrile; Salmonidae; Sex Factors; Trout | 1980 |
Strain differences in CYP3A-mediated C-8 hydroxylation (1,3,7-trimethyluric acid formation) of caffeine in Wistar and Dark Agouti rats. Rapid metabolism of caffeine in debrisoquine poor metabolizer model rats.
Topics: Aging; Animals; Aryl Hydrocarbon Hydroxylases; Caffeine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Debrisoquin; Dexamethasone; Female; Humans; Hydroxylation; Male; Methylcholanthrene; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Wistar; Sex Characteristics; Species Specificity; Troleandomycin; Uric Acid | 1998 |
Postnatal ontogeny and hormonal regulation of sulfotransferase SULT1B1 in male and female rats.
Topics: Aging; Animals; Animals, Newborn; Antibody Specificity; Blotting, Northern; Blotting, Western; Dexamethasone; Enzyme-Linked Immunosorbent Assay; Female; Glucocorticoids; Hormones; Hypophysectomy; Male; Organ Specificity; Pregnenolone Carbonitrile; Rabbits; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sulfotransferases | 1999 |
[Stress and aging].
Topics: Adaptation, Psychological; Aging; Austria; Calciphylaxis; Canada; General Adaptation Syndrome; History of Medicine; Pregnenolone Carbonitrile | 1977 |
Uptake of ouabain by isolated hepatocytes from livers of developing rats.
Topics: Aging; Animals; Biological Transport; In Vitro Techniques; Kinetics; Liver; Male; Organ Size; Ouabain; Potassium; Pregnenolone Carbonitrile; Proteins; Rats; Taurocholic Acid | 1979 |
Fine structural changes in the liver of young and old rats as influenced by microsomal enzyme inducers.
Topics: Aging; Animals; Dexamethasone; Endoplasmic Reticulum; Enzyme Induction; Liver; Male; Microsomes, Liver; Phenobarbital; Pregnenolone Carbonitrile; Rats; Spironolactone | 1979 |
Biliary excretion of drugs: role of ligandin in newborn immaturity and in the action of microsomal enzyme inducers.
Topics: Aging; Animals; Animals, Newborn; Bile; Biotransformation; Carrier Proteins; Enzyme Induction; Glutathione Transferase; In Vitro Techniques; Liver; Male; Methylcholanthrene; Microsomes, Liver; Ouabain; Phenobarbital; Pregnenolone Carbonitrile; Protein Binding; Rats; Sulfobromophthalein; Time Factors | 1975 |
Effect of age on the induction of in vitro drug metabolism by pregnenolone-16 alpha-carbonitrile (PCN); effect of age and PCN on immune responses.
Topics: Aging; Animals; B-Lymphocytes; Hemolytic Plaque Technique; Mitogens; Pharmaceutical Preparations; Pregnenolone Carbonitrile; Rats; T-Lymphocytes | 1987 |
17 beta-estradiol 2- and 4-hydroxylation catalyzed by rat hepatic cytochrome P-450: roles of individual forms, inductive effects, developmental patterns, and alterations by gonadectomy and hormone replacement.
Topics: Aging; Animals; Castration; Cytochrome P-450 Enzyme System; Enzyme Induction; Estradiol; Female; Hydroxylation; Immunologic Techniques; Liver; Male; Microsomes, Liver; Pregnenolone Carbonitrile; Rats; Testosterone | 1986 |
Stimulation of the development of the hepatic excretory mechanism for ouabain in newborn rats with microsomal enzyme inducers.
Topics: Aging; Animals; Animals, Newborn; Bile; Enzyme Induction; Liver; Methylcholanthrene; Microsomes, Liver; Ouabain; Phenobarbital; Pregnenolone Carbonitrile; Rats; Spironolactone; Time Factors; Tritium | 1974 |