pregnenolone has been researched along with Prostatic Neoplasms in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (8.00) | 29.6817 |
| 2010's | 6 (24.00) | 24.3611 |
| 2020's | 2 (8.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bian, C; Chen, L; Chen, X; Gao, Y; Hou, Z; Huang, S; Hydyr, N; Le, W; Li, Z; Lian, J; Liu, Y; Mei, Z; Tan, Q; Wu, D; Xu, C; Yang, T; Zhang, S; Zhu, X | 1 |
| Chapman, JG; Guengerich, FP; McCarty, KD; Tateishi, Y | 1 |
| Alyamani, M; Auchus, RJ; Berk, M; Li, J; Li, Z; Sharifi, N; Tang, J; Upadhyay, S | 1 |
| Chen, HL; Du, JJ; Li, YC | 1 |
| Porubek, D | 1 |
| de Jong, FH; Dits, NF; Hofland, J; Jenster, G; Schröder, FH; Steenbergen, J; van Leenders, GJ; van Weerden, WM | 1 |
| Mehtiev, AR; Misharin, AY; Novikov, RA; Stulov, SV; Timofeev, VP; Tkachev, YV; Zavialova, MG | 1 |
| Balk, SP; Bubley, GJ; Cai, C; Chen, S; Marck, B; Matsumoto, AM; Mostaghel, EA; Nelson, PS; Ng, P; Simon, NI; Wang, H | 1 |
| Haidar, S; Hartmann, RW | 1 |
| Ahlstrand, C; Berg, AA; Hammar, M; Läckgren, G | 1 |
| Hammond, GL; Kontturi, M; Lukkarinen, O; Vihko, R | 2 |
| Kontturi, M; Leinonen, P; Ruokonen, A; Vihko, R | 1 |
| Hammond, GL; Leinonen, P; Vihko, R | 1 |
| Brodie, AH; Grigoryev, DN; Long, BJ; Njar, VC | 1 |
| Hammond, GL; Kontturi, M; Vihko, P; Vihko, R | 1 |
| Horino, M; Kakita, K; Matsuki, M; Matsumura, S; Nishida, S; Omukai, Y; Oyama, H; Tanaka, H; Tenku, A | 1 |
| Rodriguez-Rigau, LJ; Smith, KD; Steinberger, E; Tcholakian, RK | 1 |
| Hammond, GL; Kontturi, M; Koskela, E; Ruokonen, A; Vihko, R | 1 |
| Bélanger, A; Brochu, M; Cusan, L; Dupont, A; Labrie, F | 1 |
| Ochi-Ai, K; Oshima, H; Sarada, T; Tamaoki, BI | 1 |
| Sarada, T | 1 |
| Troen, P; Yanaihara, T | 1 |
| Fan, DF; Oshima, H; Troen, BR; Troen, P | 1 |
| Murato, SI; Shikita, M; Tamaoki, BI | 1 |
2 review(s) available for pregnenolone and Prostatic Neoplasms
| Article | Year |
|---|---|
[Advances in the study of steroidal inhibitors of cytochrome P45017alpha].
Topics: Androstenedione; Androstenes; Androstenols; Animals; Antineoplastic Agents; Dehydroepiandrosterone; Dihydrotestosterone; Enzyme Inhibitors; Humans; Male; Molecular Structure; Pregnenolone; Progesterone; Prostatic Neoplasms; Steroid 17-alpha-Hydroxylase; Testosterone | 2013 |
CYP17A1: a biochemistry, chemistry, and clinical review.
Topics: Animals; Enzyme Inhibitors; Humans; Male; Molecular Conformation; Pregnenolone; Prostatic Neoplasms; Steroid 17-alpha-Hydroxylase | 2013 |
23 other study(ies) available for pregnenolone and Prostatic Neoplasms
| Article | Year |
|---|---|
Tracing steroidogenesis in prostate biopsy samples to unveil prostate tissue androgen metabolism characteristics and potential clinical application.
Topics: Aged; Aged, 80 and over; Androgens; Biopsy; Cell Line, Tumor; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Humans; Male; Mass Spectrometry; Pregnenolone; Prostatic Neoplasms; Steroids | 2021 |
Stepwise binding of inhibitors to human cytochrome P450 17A1 and rapid kinetics of inhibition of androgen biosynthesis.
Topics: Androgens; Androstenes; Antineoplastic Agents, Hormonal; Catalytic Domain; Cytochrome P-450 CYP3A; Enzyme Inhibitors; Humans; Imidazoles; Ketoconazole; Kinetics; Male; Naphthalenes; Pregnenolone; Progesterone; Prostatic Neoplasms; Steroid 17-alpha-Hydroxylase | 2021 |
Steroidogenic Metabolism of Galeterone Reveals a Diversity of Biochemical Activities.
Topics: 17-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androstadienes; Animals; Benzimidazoles; Cell Line, Tumor; Chromatography, High Pressure Liquid; HEK293 Cells; Humans; Hydroxysteroid Dehydrogenases; Kaplan-Meier Estimate; Male; Mice; Pregnenolone; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Steroid 17-alpha-Hydroxylase; Tandem Mass Spectrometry; Transplantation, Heterologous | 2017 |
Evidence of limited contributions for intratumoral steroidogenesis in prostate cancer.
Topics: 3-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Aged; Aged, 80 and over; Aldo-Keto Reductase Family 1 Member C3; Androgens; Androstenedione; Animals; Cell Line, Tumor; Dihydrotestosterone; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Hydroxyprostaglandin Dehydrogenases; Male; Mice; Middle Aged; Neoplasms, Experimental; Orchiectomy; Pregnenolone; Progesterone Reductase; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Steroid 17-alpha-Hydroxylase; Testosterone; Transplantation, Heterologous | 2010 |
[17(20)E]- and [17(20)Z]-pregna-5,17(20)-dien-21-oylamides. Facile synthesis and primary evaluation for cancer cells proliferation.
Topics: Androgens; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Proliferation; Female; Humans; Male; Pregnenolone; Prostatic Neoplasms | 2010 |
Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors.
Topics: Androstenedione; Androstenes; Androstenols; Animals; Antineoplastic Agents, Hormonal; Carcinoma; Cell Line, Tumor; Dehydroepiandrosterone; Female; Humans; Indomethacin; Male; Mice; Orchiectomy; Pregnenolone; Progesterone; Prostatic Neoplasms; Receptors, Androgen; Steroid 17-alpha-Hydroxylase; Up-Regulation | 2011 |
C16 and C17 substituted derivatives of pregnenolone and progesterone as inhibitors of 17alpha-hydroxylase-C17, 20-lyase: synthesis and biological evaluation.
Topics: 5-alpha Reductase Inhibitors; Animals; Enzyme Inhibitors; Humans; Male; Pregnenolone; Progesterone; Prostatic Neoplasms; Rats; Steroid Hydroxylases; Structure-Activity Relationship | 2002 |
In vitro conversion of 3H-pregnenolone by human testicular tissue from fetal age to senescence.
Topics: 3-Hydroxysteroid Dehydrogenases; Adult; Aged; Aging; Child; Child, Preschool; Cryptorchidism; Female; Fetus; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Male; Middle Aged; Pregnancy; Pregnenolone; Prostatic Neoplasms; Puberty; Steroid 17-alpha-Hydroxylase; Testis; Testosterone | 1984 |
Long-term effects of endocrine treatment on serum steroids in advanced prostatic carcinoma patients.
Topics: Aged; Androstenedione; Androsterone; Castration; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Humans; Hydroxyprogesterones; Male; Middle Aged; Organophosphorus Compounds; Pregnenolone; Progesterone; Prostatic Neoplasms; Steroids; Testosterone | 1980 |
Effects of estrogen treatment on human testicular unconjugated steroid and steroid sulfate production in vivo.
Topics: Adult; Aged; Androgens; Antineoplastic Agents; Diethylstilbestrol; Estradiol; Estradiol Congeners; Humans; Male; Middle Aged; Organophosphorus Compounds; Pregnenolone; Progesterone; Prostatic Neoplasms; Steroids; Sulfuric Acids; Testis | 1981 |
Testosterone and some of its precursors and metabolites in the human epididymis.
Topics: Aged; Androstane-3,17-diol; Androstenedione; Androsterone; Dihydrotestosterone; Epididymis; Estrogens; Humans; Hydroxyprogesterones; Male; Middle Aged; Pregnenolone; Progesterone; Prostatic Neoplasms; Testis; Testosterone; Vas Deferens | 1980 |
Pregnenolone stimulates LNCaP prostate cancer cell growth via the mutated androgen receptor.
Topics: Animals; Binding, Competitive; Cell Division; Cell Line; Dexamethasone; Dihydrotestosterone; Gene Expression Regulation; Humans; Male; Mice; Mice, SCID; Mutation; Neoplasm Transplantation; Pregnenolone; Prostatic Neoplasms; Receptors, Androgen; Steroids; Transfection; Transplantation, Heterologous; Tumor Cells, Cultured | 2000 |
Serum steroids in normal males and patients with prostatic diseases.
Topics: Adult; Aged; Aging; Androstenedione; Androsterone; Dihydrotestosterone; Estradiol; Humans; Hydroxyprogesterones; Male; Middle Aged; Pregnenolone; Progesterone; Prostatic Hyperplasia; Prostatic Neoplasms; Reference Values; Steroids; Testosterone | 1978 |
Dexamethasone suppressibility of plasma pregnenolone or dehydroepiandrosterone in gonadectomized patients.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Breast Neoplasms; Castration; Dehydroepiandrosterone; Dexamethasone; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Pregnenolone; Prostatic Neoplasms | 1979 |
Testicular steroid secretion and peripheral serum steroid concentrations in patients with prostatic carcinoma after short-term estrogen treatment.
Topics: Androgens; Estradiol; Estrogens; Humans; Male; Pregnenolone; Progesterone; Prostatic Neoplasms; Spermatic Cord; Testis; Testosterone; Time Factors | 1979 |
In vitro steroid metabolic studies in human testes. II: Metabolism of cholesterol, pregnenolone, progesterone, androstenedione and testosterone by testes of an estrogen-treated man.
Topics: Adult; Androgens; Androstenedione; Cholesterol; Estradiol Congeners; Estrogens; Ethinyl Estradiol; Humans; Male; Pregnenolone; Progesterone; Progestins; Prostatic Neoplasms; Testis; Testosterone; Transsexualism | 1977 |
The simultaneous radioimmunoassay of seven steroids in human spermatic and peripheral venous blood.
Topics: Adult; Aged; Androstenedione; Androsterone; Dihydrotestosterone; Hormones; Humans; Male; Middle Aged; Pregnenolone; Progesterone; Prostatic Neoplasms; Radioimmunoassay; Steroids; Testis; Testosterone | 1977 |
Endocrine effects of combined treatment with an LHRH agonist in association with flutamide in metastatic prostatic carcinoma.
Topics: Adenocarcinoma; Adrenal Cortex Hormones; Androgens; Androstane-3,17-diol; Androstenediol; Androstenedione; Androsterone; Anilides; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Dehydroepiandrosterone; Flutamide; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Hydrocortisone; Kinetics; Luteinizing Hormone; Male; Pregnenolone; Progesterone; Prolactin; Prostatic Neoplasms; Testosterone; Triptorelin Pamoate | 1988 |
Intracellular distribution and properties of steroid 16-alpha-hydroxylase in human testes.
Topics: Aged; Androgens; Carbon Isotopes; Castration; Chromatography, Thin Layer; Dehydroepiandrosterone; Hexestrol; Humans; Hydroxyprogesterones; In Vitro Techniques; Male; Microsomes; Middle Aged; Mixed Function Oxygenases; Pregnenolone; Progesterone; Prostatic Neoplasms; Testis | 1967 |
[Metabolism of steroids in normal and pathological human adrenal glands].
Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Glands; Adult; Androgens; Carbon Isotopes; Child, Preschool; Chromatography, Thin Layer; Cushing Syndrome; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Male; Middle Aged; Pregnenolone; Prostatic Neoplasms | 1971 |
Studies of the human testis. I. Biosynthetic pathways for androgen formation in human testicular tissue in vitro.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Aged; Androstanes; Carbon Isotopes; Chromatography, Paper; Dehydroepiandrosterone; Humans; Hydroxyprogesterones; In Vitro Techniques; Male; Middle Aged; Pregnenolone; Progesterone; Prostatic Neoplasms; Testis; Testosterone; Time Factors; Tritium | 1972 |
Studies of the human testis. IV. Testicular 20 alpha-hydroxysteroid dehydrogenase and steroid 17 alpha-hydroxylase.
Topics: Binding, Competitive; Carbon Radioisotopes; Chromatography, Thin Layer; Cytosol; Humans; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Kinetics; Male; Microsomes; Mitochondria; Pregnenolone; Progesterone; Prostatic Neoplasms; Protein Binding; Solubility; Steroid Hydroxylases; Structure-Activity Relationship; Testis; Time Factors; Ultracentrifugation | 1974 |
Androgen formation in the testicular tissue of patients with prostatic carcinoma.
Topics: 17-Ketosteroids; Aged; Androgens; Humans; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Lyases; Male; Microsomes; Middle Aged; Mitochondria; Mixed Function Oxygenases; Pregnenolone; Progesterone; Prostatic Neoplasms; Testis; Testosterone | 1966 |