Page last updated: 2024-08-20

pregnenolone and Interstitial Cell Tumor

pregnenolone has been researched along with Interstitial Cell Tumor in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199032 (71.11)18.7374
1990's6 (13.33)18.2507
2000's6 (13.33)29.6817
2010's1 (2.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bailey, JL; Enangue Njembele, AN; Tremblay, JJ1
Cui, LB; Hong, X; Song, L; Wang, XR; Wang, YB; Zhang, ZD1
Chen, JF; Hong, X; Qu, JH; Song, L; Sun, H; Wang, SL; Wang, XR; Wang, YB; Xu, XL1
Bakker, GH; Hoogerbrugge, W; Rommerts, FF; van der Molen, HJ1
Bakker, GH; Rommerts, FF; van der Molen, HJ1
Ascoli, M; Puett, D; Segaloff, DL1
Ascoli, M; Freeman, DA; Sheets, JJ; Vickery, LE1
Bakker, GH; Hoogerbrugge, JW; Rommerts, FF; van der Molen, HJ2
Flinterman, JF; Merz, WE; Rommerts, FF; van Gelderen-Boele, S; van Loenen, HJ1
Clark, BJ; Stocco, DM; Wells, J1
Freeman, DA; Gocze, PM1
Huang, BM; Lai, HY; Liu, MY; Tsai, ML; Yang, BC; Yang, HY1
King, SR; Rommerts, FF; Span, PN1
Huang, BM; Lai, HY; Liu, MY1
Huseby, RA; Matsumoto, K; Samuels, LT; Sato, B1
Abraham, GE; Bossen, EH; Soules, MR1
Bakker, CP; Cooke, BA; Janszen, FH; Lindh, LM; van der Molen, HJ; van der Plank, MP; van Driel, MJ1
Ascoli, M; Lacroix, A; McKenna, TJ; Puett, D1
Berkovich, A; Costa, E; Guidotti, A; Krueger, KE; Papadopoulos, V1
Cooke, BA; West, AP1
Brandt, ME; Brodie, AM; Melner, MH; Puett, D; Zimniski, SJ1
Freeman, DA; Nagy, L1
Kilgore, MW; Stocco, DM1
Hoogerbrugge, JW; Rommerts, FF; Teerds, KJ1
Rommerts, FF; Terpstra, P; van der Molen, HJ1
Freeman, DA2
Rommerts, FF; van Amerongen, A; van Noort, M; Wirtz, KW1
Melner, MH; Puett, D; Zimniski, SJ1
Brandt, ME; Covey, DF; Melner, MH; Puett, D; Zimniski, SJ1
Grant, JK; Griffiths, K; Pierrepoint, CG; Stewart, JS1
Lucis, OJ; Lucis, R1
Allison, JE; Bardin, CW; Gumbreck, LG; Schneider, G; Stanley, AJ; Vanha-Perttula, T1
Ances, IG; Connor, TB; Gallaher, EP; Ganis, FM; Levin, HS; Migeon, CJ1
Coupey, S; Jull, JW; McClellan, D1
Neville, AM; Richards, G1
Hurst, L; Jayle, MF; Lacassagne, A1
Temple, R; Wolff, J1
Shin, SI1
Ficher, M; Root, A; Smith, KD; Steinberger, E1
Sato, GH; Shin, SI; Yasumura, Y1
Ficher, M; Steinberger, A; Steinberger, E1
Inano, H; Tamaoki, BI; Tsubura, Y1
Inano, H; Machino, A; Tamaoki, BI; Tsubura, Y1

Reviews

1 review(s) available for pregnenolone and Interstitial Cell Tumor

ArticleYear
Study of spermatogenesis and steroid metabolism in cultures of mammalian testes.
    Recent progress in hormone research, 1970, Volume: 26

    Topics: Age Factors; Animals; Chorionic Gonadotropin; Culture Media; Culture Techniques; Leydig Cell Tumor; Leydig Cells; Male; Pregnenolone; Progesterone; Rats; Sertoli Cells; Spermatozoa; Steroids; Testis; Testosterone; Thymidine; Tritium

1970

Other Studies

44 other study(ies) available for pregnenolone and Interstitial Cell Tumor

ArticleYear
In vitro exposure of Leydig cells to an environmentally relevant mixture of organochlorines represses early steps of steroidogenesis.
    Biology of reproduction, 2014, Volume: 90, Issue:6

    Topics: Animals; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Cyclic AMP; Endocrine Disruptors; Environmental Pollutants; Hydrocarbons, Chlorinated; Hydroxycholesterols; Leydig Cell Tumor; Leydig Cells; Male; Mice; Phosphoproteins; Pregnenolone; Progesterone; Steroids; Testicular Neoplasms

2014
Monobutyl phthalate inhibits steroidogenesis by downregulating steroidogenic acute regulatory protein expression in mouse Leydig tumor cells (MLTC-1).
    Journal of toxicology and environmental health. Part A, 2007, Volume: 70, Issue:11

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Line, Tumor; Cell Survival; Cholera Toxin; Chorionic Gonadotropin; Cyclic AMP; DNA Replication; Dose-Response Relationship, Drug; Down-Regulation; Drug Combinations; Endocrine Disruptors; Humans; Hydroxycholesterols; Leydig Cell Tumor; Male; Mice; Mitochondria; Phosphoproteins; Phthalic Acids; Pregnenolone; Progesterone; RNA, Messenger; Testicular Neoplasms

2007
Fenvalerate inhibits progesterone production through cAMP-dependent signal pathway.
    Toxicology letters, 2008, Jan-04, Volume: 176, Issue:1

    Topics: Animals; Cell Line, Tumor; Cell Survival; Cholera Toxin; Cholesterol Side-Chain Cleavage Enzyme; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxycholesterols; Insecticides; Leydig Cell Tumor; Male; Mice; Nitriles; Phosphoproteins; Pregnenolone; Progesterone; Pyrethrins; RNA, Messenger; Signal Transduction

2008
LH-dependent steroid production and protein phosphorylation in culture of rat tumour Leydig cells.
    Molecular and cellular endocrinology, 1983, Volume: 33, Issue:2-3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cell Line; Hydroxycholesterols; Leydig Cell Tumor; Luteinizing Hormone; Molecular Weight; Phosphoproteins; Pregnenolone; Protein Kinases; Rats

1983
Actions of luteinizing hormone on protein phosphorylation and steroidogenesis in tumor Leydig cells.
    Advances in cyclic nucleotide and protein phosphorylation research, 1984, Volume: 17

    Topics: 1-Methyl-3-isobutylxanthine; Cells, Cultured; Cycloheximide; Cytochalasin B; Cytosol; Leydig Cell Tumor; Luteinizing Hormone; Microsomes; Phosphoproteins; Phosphorylation; Pregnenolone; Protein Biosynthesis; Protein Kinases; Steroids

1984
Characterization of the desensitized state of Leydig tumor cells.
    Biochimica et biophysica acta, 1981, Jul-17, Volume: 675, Issue:3-4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aminoglutethimide; Animals; Cell Line; Cholera Toxin; Cholesterol; Cholesterol Esters; Chorionic Gonadotropin; Cyclic AMP; Leydig Cell Tumor; Mice; Pregnenolone; Steroids

1981
Inhibition of steroidogenesis in cultured Leydig tumor cells by 22-amino-23,24-bisnor-5-cholen-3 beta-O1 and (20R) 20-phenyl-5-pregnene-3 beta,20-diol.
    Endocrinology, 1983, Volume: 113, Issue:1

    Topics: Aminoglutethimide; Animals; Cattle; Cholesterol; Chorionic Gonadotropin; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Leydig Cell Tumor; Male; Pregnenes; Pregnenolone; Progesterone; Testicular Neoplasms; Time Factors

1983
Subcellular localization of LH-dependent phosphoproteins and their possible role in regulation of steroidogenesis in rat tumour Leydig cells.
    FEBS letters, 1983, Sep-05, Volume: 161, Issue:1

    Topics: Animals; Cytochalasin B; Cytosol; Dactinomycin; Leydig Cell Tumor; Luteinizing Hormone; Microsomes; Molecular Weight; Neoplasm Proteins; Neoplasms, Experimental; Phosphoproteins; Pregnenolone; Protein Biosynthesis; Rats; Subcellular Fractions; Transcription, Genetic

1983
Lutropin increases phosphorylation of a 33 000-dalton ribosomal protein in rat tumour Leydig cells.
    The Biochemical journal, 1982, Jun-15, Volume: 204, Issue:3

    Topics: Animals; Cycloheximide; Electrophoresis, Polyacrylamide Gel; In Vitro Techniques; Leydig Cell Tumor; Luteinizing Hormone; Male; Molecular Weight; Phosphoproteins; Phosphorylation; Pregnenolone; Puromycin; Rats; Rats, Inbred Strains; Ribosomal Proteins; Subcellular Fractions

1982
The relative importance of the oligosaccharide units in human chorionic gonadotropin (CG) for LH/CG receptor activation in rat Leydig cells and mouse Leydig tumor cells.
    The Journal of endocrinology, 1995, Volume: 147, Issue:2

    Topics: Animals; Cell Line; Chorionic Gonadotropin; Cyclic AMP; Glycosylation; Hydrofluoric Acid; Leydig Cell Tumor; Leydig Cells; Male; Mice; Oligosaccharides; Pregnenolone; Rats; Rats, Wistar; Receptors, Gonadotropin; Stimulation, Chemical

1995
The effects of hydrogen peroxide on steroidogenesis in mouse Leydig tumor cells.
    Endocrinology, 1993, Volume: 133, Issue:6

    Topics: Animals; Bucladesine; Hydrogen Peroxide; Hydroxycholesterols; Leydig Cell Tumor; Mice; Mitochondria; Neoplasm Proteins; Pregnenolone; Progesterone; Proteins; Steroids; Tumor Cells, Cultured

1993
Cytotoxic effects of cigarette smoke alkaloids inhibit the progesterone production and cell growth of cultured MA-10 Leydig tumor cells.
    European journal of obstetrics, gynecology, and reproductive biology, 2000, Volume: 93, Issue:1

    Topics: 20-alpha-Dihydroprogesterone; Alkaloids; Anabasine; Cell Division; Cholesterol Side-Chain Cleavage Enzyme; Corpus Luteum; Cotinine; DNA; Female; Humans; Leydig Cell Tumor; Nicotiana; Nicotine; Ovarian Neoplasms; Plants, Toxic; Pregnenolone; Progesterone; Smoke; Tumor Cells, Cultured

2000
The inhibitory effects of lead on steroidogenesis in MA-10 mouse Leydig tumor cells.
    Life sciences, 2001, Jan-12, Volume: 68, Issue:8

    Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Bucladesine; Cadmium; Calcium Channel Blockers; Calcium Channels; Chorionic Gonadotropin; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Hydroxycholesterols; Lead; Leydig Cell Tumor; Leydig Cells; Male; Mice; Organometallic Compounds; Phosphoproteins; Pregnenolone; Progesterone; Signal Transduction; Stimulation, Chemical; Tumor Cells, Cultured

2001
Implications of progesterone metabolism in MA-10 cells for accurate measurement of the rate of steroidogenesis.
    Endocrinology, 2001, Volume: 142, Issue:12

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Antibodies; Bucladesine; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Hydroxysteroid Dehydrogenases; Leydig Cell Tumor; Male; Mice; Pregnenolone; Progesterone; Radioimmunoassay; Steroids; Time Factors; Tumor Cells, Cultured

2001
Concentration dependency in lead-inhibited steroidogenesis in MA-10 mouse Leydig tumor cells.
    Journal of toxicology and environmental health. Part A, 2002, Apr-12, Volume: 65, Issue:7

    Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Chorionic Gonadotropin; Dose-Response Relationship, Drug; Hydroxycholesterols; Immunoblotting; Lead; Leydig Cell Tumor; Leydig Cells; Male; Mice; Mitochondria; Phosphoproteins; Pregnenolone; Progesterone; Radioimmunoassay; Signal Transduction; Time Factors; Tumor Cells, Cultured

2002
Molecular nature of interaction of steroids with biomembranes related to androgen biosynthesis.
    Journal of steroid biochemistry, 1979, Volume: 11, Issue:4

    Topics: 3-Hydroxysteroid Dehydrogenases; Androgens; Animals; Cryptorchidism; Cytosol; Endoplasmic Reticulum; Intracellular Membranes; Leydig Cell Tumor; Magnesium; Male; Mice; Mitochondria; Pregnenolone; Progesterone; Receptors, Steroid; Testicular Neoplasms

1979
The steroid profile of a virilizing ovarian tumor.
    Obstetrics and gynecology, 1978, Volume: 52, Issue:1

    Topics: 17-alpha-Hydroxypregnenolone; Adult; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Female; Granulosa Cell Tumor; Hormones; Humans; Hydroxyprogesterones; Leydig Cell Tumor; Neoplasms, Gonadal Tissue; Ovarian Neoplasms; Pregnenolone; Sertoli Cell Tumor; Testosterone; Virilism

1978
A Leydig cell tumour: a model for the study of lutropin action.
    Biochimica et biophysica acta, 1979, Mar-22, Volume: 583, Issue:3

    Topics: Animals; Cyclic AMP; Leydig Cell Tumor; Leydig Cells; Luteinizing Hormone; Male; Models, Biological; Neoplasm Proteins; Neoplasms, Experimental; Pregnenolone; Protein Kinases; Rats; Testicular Neoplasms; Testosterone

1979
Steroidogenesis in HCG-responsive Leydig cell tumor variants.
    Journal of steroid biochemistry, 1979, Volume: 10, Issue:6

    Topics: 17-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androstenedione; Animals; Chorionic Gonadotropin; Dihydrotestosterone; Hydroxyprogesterones; Leydig Cell Tumor; Male; Mice; Neoplasms, Hormone-Dependent; Pregnenolone; Progesterone; Steroid 17-alpha-Hydroxylase; Steroids; Testosterone

1979
Diazepam binding inhibitor and its processing products stimulate mitochondrial steroid biosynthesis via an interaction with mitochondrial benzodiazepine receptors.
    Endocrinology, 1991, Volume: 129, Issue:3

    Topics: Adrenal Cortex; Adrenal Gland Neoplasms; Amino Acid Sequence; Animals; Brain; Cell Line; Chromatography, High Pressure Liquid; Diazepam Binding Inhibitor; Kinetics; Leydig Cell Tumor; Mice; Mitochondria; Molecular Sequence Data; Neuropeptides; Peptide Fragments; Peptides; Pregnenolone; Rats; Receptors, GABA-A; Steroids

1991
A novel method to modulate desensitization and truncation of luteinizing hormone receptors using antisense oligodeoxynucleotides.
    Molecular and cellular endocrinology, 1991, Volume: 79, Issue:1-3

    Topics: Animals; Base Sequence; Bucladesine; Cyclic AMP; Leydig Cell Tumor; Luteinizing Hormone; Mice; Molecular Sequence Data; Oligonucleotides, Antisense; Pregnenolone; Receptors, LH; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1991
Effect of 4-hydroxyandrostenedione on murine Leydig tumor cell steroidogenesis.
    Cancer research, 1991, Jul-15, Volume: 51, Issue:14

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Leydig Cell Tumor; Male; Mice; Pargyline; Pregnenolone; Progesterone; Testosterone

1991
Effect of cholesterol transport inhibitors on steroidogenesis and plasma membrane cholesterol transport in cultured MA-10 Leydig tumor cells.
    Endocrinology, 1990, Volume: 126, Issue:5

    Topics: Biological Transport; Bucladesine; Cell Membrane; Cholesterol; Cholesterol, LDL; Colchicine; Cytochalasin D; Leydig Cell Tumor; Nigericin; Pregnenolone; Progesterone; Trifluoperazine; Tumor Cells, Cultured

1990
Initial characterization of a subclone of the MA-10 mouse Leydig tumor cell line.
    Endocrinology, 1989, Volume: 124, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 3-Hydroxysteroid Dehydrogenases; Animals; Bucladesine; Cholesterol Side-Chain Cleavage Enzyme; Chorionic Gonadotropin; Clone Cells; Cyclic AMP; Leydig Cell Tumor; Mice; Pregnenolone; Progesterone; Testosterone; Tumor Cells, Cultured

1989
In vitro effects of ethylene-dimethane sulfonate (EDS) on Leydig cells: inhibition of steroid production and cytotoxic effects are dependent on species and age of rat.
    Molecular and cellular endocrinology, 1988, Volume: 55, Issue:1

    Topics: Adenosine Triphosphate; Aging; Alkylating Agents; Animals; Cells, Cultured; Hydroxycholesterols; Leydig Cell Tumor; Leydig Cells; Liver; Luteinizing Hormone; Male; Mesylates; Mice; Pregnenolone; Proteins; Rats; Sertoli Cells; Sexual Maturation; Species Specificity; Testicular Neoplasms; Testis

1988
Are polyphosphorylated phospholipids involved in the hormonal control of cholesterol side-chain cleavage activity in tumour Leydig cells?
    Journal of steroid biochemistry, 1985, Volume: 22, Issue:6

    Topics: Animals; Bucladesine; Cardiolipins; Cycloheximide; Cytochrome P-450 Enzyme System; Leydig Cell Tumor; Leydig Cells; Luteinizing Hormone; Male; Mitochondria; Phosphatidylethanolamines; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phospholipids; Pregnenolone; Quinacrine

1985
Constitutive steroidogenesis in the R2C Leydig tumor cell line is maintained by the adenosine 3',5'-cyclic monophosphate-independent production of a cycloheximide-sensitive factor that enhances mitochondrial pregnenolone biosynthesis.
    Endocrinology, 1987, Volume: 120, Issue:1

    Topics: Animals; Bucladesine; Cell Line; Cyclic AMP; Cycloheximide; Cytoplasm; Lactates; Leydig Cell Tumor; Leydig Cells; Male; Mitochondria; Pregnenolone; Progesterone; Protein Kinases; Rats

1987
Intracellular redistribution of SCP2 in Leydig cells after hormonal stimulation may contribute to increased pregnenolone production.
    Biochemical and biophysical research communications, 1988, Jul-15, Volume: 154, Issue:1

    Topics: Animals; Carrier Proteins; Cell Line; Leydig Cell Tumor; Leydig Cells; Luteinizing Hormone; Male; Mitochondria; Plant Proteins; Pregnenolone; Sterols; Subcellular Fractions; Testicular Neoplasms

1988
Estradiol acts as a competitive inhibitor of the 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase enzyme of cultured Leydig tumor cells.
    Endocrinology, 1985, Volume: 117, Issue:5

    Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Binding, Competitive; Cells, Cultured; Estradiol; Leydig Cell Tumor; Male; Mice; Pregnenolone; Progesterone

1985
Induction of an estrogen-dependent early steroidogenic lesion in murine Leydig tumor cells.
    Endocrinology, 1985, Volume: 116, Issue:6

    Topics: Animals; Cells, Cultured; Chorionic Gonadotropin; Estradiol; Estrogens; Leydig Cell Tumor; Male; Mice; Mice, Inbred C57BL; Neoplasms, Hormone-Dependent; Pregnenolone; Progesterone; Receptors, Estrogen; Steroids; Testicular Neoplasms

1985
Inhibition of Leydig tumor cell steroidogenesis by 10-propargylestr-4-ene-3,17-dione, an irreversible aromatase inhibitor.
    Cancer research, 1985, Volume: 45, Issue:10

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Leydig Cell Tumor; Male; Mice; Mice, Inbred C57BL; Oxidoreductases; Pargyline; Pregnenolone; Progesterone; Testicular Neoplasms; Testosterone

1985
Neutral steroid sulphation and oestrogen biosynthesis in vitro by a feminizing Leydig cell tumour of the testis.
    The Journal of endocrinology, 1966, Volume: 35, Issue:4

    Topics: 17-alpha-Hydroxypregnenolone; Adult; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Estriol; Humans; Hydroxyprogesterones; In Vitro Techniques; Leydig Cell Tumor; Male; Pregnenolone; Sulfates

1966
Conversion of dehydroepiandrosterone, pregnenolone, and progesterone by interstitial cell tumor tissue.
    Cancer research, 1970, Volume: 30, Issue:3

    Topics: Androstanes; Animals; Carbon Isotopes; Chromatography; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Female; Leydig Cell Tumor; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Pregnenolone; Progesterone; Testosterone; Tritium

1970
Testicular tumors in the androgen insensitive pseudohermaphrodite rat: histochemistry and steroid metabolism.
    Gynecologic investigation, 1970, Volume: 1, Issue:3

    Topics: Animals; Carbon Isotopes; Chromatography, Thin Layer; Dehydroepiandrosterone; Disease Models, Animal; Disorders of Sex Development; Histocytochemistry; Hydroxysteroid Dehydrogenases; Leydig Cell Tumor; Leydig Cells; Male; Oxidoreductases; Pregnenolone; Rats; Sertoli Cell Tumor; Testicular Neoplasms; Testis; Tritium

1970
Case of feminizing interstitial cell tumor of the testicle. Clinical and biochemical evaluation.
    The Journal of clinical endocrinology and metabolism, 1971, Volume: 33, Issue:3

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Androgen-Insensitivity Syndrome; Androstanes; Chromatography, Paper; Dehydroepiandrosterone; Estradiol; Estriol; Humans; In Vitro Techniques; Leydig Cell Tumor; Male; Pregnanediol; Pregnanetriol; Pregnenolone; Testosterone; Tritium

1971
Steroid metabolism by an oestrogen-dependent interstitial-cell tumour of a rat testis.
    The Journal of endocrinology, 1973, Volume: 59, Issue:1

    Topics: Androstenedione; Androstenes; Androsterone; Animals; Carbon Radioisotopes; Cholesterol; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Etiocholanolone; In Vitro Techniques; Leydig Cell Tumor; Male; Pregnenolone; Rats; Steroids; Testicular Neoplasms; Testosterone

1973
Steroid metabolism in vitro by an interstitial cell tumour and the attached prepubertal testis.
    The Journal of endocrinology, 1973, Volume: 59, Issue:3

    Topics: Adolescent; Androstenedione; Carbon Radioisotopes; Chromatography, Thin Layer; Dehydroepiandrosterone; Humans; Hydroxyprogesterones; Leydig Cell Tumor; Male; Pregnenolone; Progesterone; Puberty; Steroids; Testicular Neoplasms; Testis; Testosterone; Tritium

1973
[Inhibitory actions of pregnenolone on cancerization of the liver, and favourable to the development of neoplasms of the interstitial gland of the testis, in rats poisoned by para-dimethylaminoazobenzene (DAB)].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1971, Jan-04, Volume: 272, Issue:1

    Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Age Factors; Animals; Body Weight; Carcinoma, Hepatocellular; Hypertrophy; Leydig Cell Tumor; Liver; Liver Neoplasms; Male; Organ Size; p-Dimethylaminoazobenzene; Pregnenolone; Progesterone; Prostate; Protein Deficiency; Rats; Riboflavin Deficiency; Seminal Vesicles; Spermatozoa; Testicular Neoplasms

1971
Stimulation of steroid secretion by antimicrotubular agents.
    The Journal of biological chemistry, 1973, Apr-25, Volume: 248, Issue:8

    Topics: Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Cell Line; Chromatography, Thin Layer; Colchicine; Cyclic AMP; Deuterium; Hydroxysteroids; Ketosteroids; Leydig Cell Tumor; Mice; Microtubules; Mitosis; Podophyllotoxin; Pregnenes; Pregnenolone; Protein Biosynthesis; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Stimulation, Chemical; Time Factors; Vinblastine

1973
Studies on interstitial cells in tissue culture: steroid biosynthesis in monolayers of mouse testicular interstitial cells.
    Endocrinology, 1967, Volume: 81, Issue:3

    Topics: Adenine Nucleotides; Animals; Chorionic Gonadotropin; Culture Techniques; Cycloheximide; Follicle Stimulating Hormone; Leydig Cell Tumor; Leydig Cells; Luteinizing Hormone; Male; Mice; Microscopy, Phase-Contrast; NAD; NADP; Neoplasm Transplantation; Pregnenolone; Progesterone; Prolactin; Testis

1967
The role of androgens in the initiation of spermatogenesis in man.
    The Journal of clinical endocrinology and metabolism, 1973, Volume: 37, Issue:5

    Topics: Androstenedione; Biopsy; Carbon Radioisotopes; Child; Cholesterol; Humans; Leydig Cell Tumor; Male; Pregnenolone; Progesterone; Spermatogenesis; Testis; Testosterone; Tritium

1973
Studies on interstitial cells in tissue culture. II. Steroid biosynthesis by a clonal line of rat testicular interstitial cells.
    Endocrinology, 1968, Volume: 82, Issue:3

    Topics: Animals; Clone Cells; Culture Techniques; Leydig Cell Tumor; Male; Microscopy, Phase-Contrast; Neoplasm Transplantation; Pregnenolone; Progesterone; Rats; Spectrophotometry; Steroids

1968
Steroid biosynthesis in vitro by transplantable interstitial cell tumor of mice. 3. Metabolism of pregnenolone in the cultured tumor cell.
    Endocrinology, 1972, Volume: 90, Issue:1

    Topics: Animals; Carbon Isotopes; Cell Line; Hydroxysteroid Dehydrogenases; Leydig Cell Tumor; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Pregnanes; Pregnenolone; Sterols; Testis; Transplantation, Homologous; Tritium

1972
Steroid biosynthesis in vitro by transplantable interstitial cell tumor of mice. I. Identification and quantitative determination of the metabolites and intracellular distributon of the enzymes related to testosterone formation.
    Endocrinology, 1968, Volume: 83, Issue:4

    Topics: Animals; Carbon Isotopes; Chromatography, Thin Layer; Crystallization; Desoxycorticosterone; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Leydig Cell Tumor; Lyases; Male; Mice; Mixed Function Oxygenases; Neoplasm Transplantation; Neoplasms, Experimental; Pregnenolone; Progesterone; Testicular Neoplasms; Testosterone

1968