Page last updated: 2024-08-20

pregnenolone and Experimental Neoplasms

pregnenolone has been researched along with Experimental Neoplasms in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199027 (93.10)18.7374
1990's1 (3.45)18.2507
2000's0 (0.00)29.6817
2010's1 (3.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de Jong, FH; Dits, NF; Hofland, J; Jenster, G; Schröder, FH; Steenbergen, J; van Leenders, GJ; van Weerden, WM1
BUONASSISI, V; SATO, G; STOLLAR, V1
BRYSON, MJ; SWEAT, ML1
Auersperg, N; Mauldin, D; Sanderson, RA; Wan, MW; Wong, KS1
Antila, E; Wartiovaara, J1
Arunachalam, T; Caspi, E; Mason, JI1
Aberhart, DJ; Mason, JI; Murry, BA1
Bakker, GH; Hoogerbrugge, JW; Rommerts, FF; van der Molen, HJ1
Chasin, M; Rivkin, I1
Auersperg, N; Chen, LM1
Mason, JI; Robidoux, WF3
Bakker, CP; Cooke, BA; Janszen, FH; Lindh, LM; van der Molen, HJ; van der Plank, MP; van Driel, MJ1
Auersperg, N; MacLaren, IA; Wong, A1
Counsell, RE; Schwendner, SW; Van Dort, M1
Lucis, OJ; Lucis, R1
Cameron, EH; Maynard, PV2
Rice, BF; Segaloff, A1
Pierson, RW1
Dominguez, OV; Huseby, RA1
Schimmer, BP1
Kowal, J2
Hashimoto, K; Sharma, RK1
Brush, JS; Sharma, RK; Sutliff, LS1
Inano, H; Tamaoki, BI; Tsubura, Y1
Inano, H; Machino, A; Tamaoki, BI; Tsubura, Y1

Other Studies

29 other study(ies) available for pregnenolone and Experimental Neoplasms

ArticleYear
Evidence of limited contributions for intratumoral steroidogenesis in prostate cancer.
    Cancer research, 2010, Feb-01, Volume: 70, Issue:3

    Topics: 3-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Aged; Aged, 80 and over; Aldo-Keto Reductase Family 1 Member C3; Androgens; Androstenedione; Animals; Cell Line, Tumor; Dihydrotestosterone; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Hydroxyprostaglandin Dehydrogenases; Male; Mice; Middle Aged; Neoplasms, Experimental; Orchiectomy; Pregnenolone; Progesterone Reductase; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Steroid 17-alpha-Hydroxylase; Testosterone; Transplantation, Heterologous

2010
STUDIES ON HORMONE SECRETING ADRENOCORTICAL TUMOR IN TISSUE CULTURE.
    Experimental cell research, 1964, Volume: 35

    Topics: Adenine Nucleotides; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Ascorbic Acid; Histocytochemistry; Metabolism; NADP; Neoplasms, Experimental; Oxidoreductases; Pharmacology; Pregnenolone; Research; Tissue Culture Techniques

1964
LOSS OF TWO STEROID 11 BETA-HYDROXYLATING COMPONENTS IN A RAT ADRENOCORTICAL CARCINOMA.
    Journal of the National Cancer Institute, 1964, Volume: 33

    Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocortical Carcinoma; Desoxycorticosterone; Metabolism; Neoplasms; Neoplasms, Experimental; Pregnenolone; Progesterone; Rats; Research

1964
Morphological and functional differentiation of Kirsten murine sarcoma virus-transformed rat adrenocortical cell lines.
    Cancer research, 1981, Volume: 41, Issue:5

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Animals; Cell Differentiation; Cell Transformation, Viral; Cells, Cultured; Epithelium; Extracellular Space; Kirsten murine sarcoma virus; Male; Neoplasm Transplantation; Neoplasms, Experimental; Pregnenolone; Rats; Sarcoma Viruses, Murine

1981
Metabolism of steroids by mouse teratocarcinoma cells.
    Journal of steroid biochemistry, 1980, Volume: 13, Issue:4

    Topics: Androstenedione; Animals; Cells, Cultured; Dehydroepiandrosterone; Estradiol; Fibroblasts; Kinetics; Mice; Neoplasms, Experimental; Pregnenolone; Progesterone; Steroids; Teratoma

1980
In vitro studies of the adrenal metabolism of halogenated side-chain analogues of cholesterol.
    Biochimica et biophysica acta, 1983, Jul-12, Volume: 752, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Animals; Calcium; Cholesterol; In Vitro Techniques; Male; Mitochondria; Neoplasms, Experimental; Pregnenolone; Rats; Rats, Inbred Strains

1983
The synthesis and metabolism of [6-3H]-25-hydroxycholesterol in rat adrenal tumor cells.
    Journal of steroid biochemistry, 1983, Volume: 18, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Animals; Chemical Phenomena; Chemistry; Hydroxycholesterols; Kinetics; Male; Mitochondria; Neoplasms, Experimental; Pregnenolone; Rats; Rats, Inbred Strains

1983
Subcellular localization of LH-dependent phosphoproteins and their possible role in regulation of steroidogenesis in rat tumour Leydig cells.
    FEBS letters, 1983, Sep-05, Volume: 161, Issue:1

    Topics: Animals; Cytochalasin B; Cytosol; Dactinomycin; Leydig Cell Tumor; Luteinizing Hormone; Microsomes; Molecular Weight; Neoplasm Proteins; Neoplasms, Experimental; Phosphoproteins; Pregnenolone; Protein Biosynthesis; Rats; Subcellular Fractions; Transcription, Genetic

1983
Lack of steroidogenic response to cyclic AMP and ACTH in adrenal cells from rats bearing the MtTF4 tumor.
    Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 217, Issue:2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Cholesterol; Corticosterone; Cyclic AMP; Female; Male; Neoplasms, Experimental; Pituitary Neoplasms; Pregnenolone; Progesterone; Rats; Stimulation, Chemical; Theophylline

1975
Response to ACTH and dibutyryl cyclic AMP by enucleated adrenocortical tumor cells.
    Molecular and cellular endocrinology, 1976, Volume: 4, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Bucladesine; Cell Line; Culture Media; Cytochalasin B; Cytoplasm; Leucine; Neoplasms, Experimental; Pregnenolone; Protein Biosynthesis; Steroids; Time Factors

1976
Pregnenolone biosynthesis in isolated cells of Snell rat adrenocortical carcinoma 494.
    Molecular and cellular endocrinology, 1978, Volume: 12, Issue:3

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Carcinoma; Cholesterol; Cycloheximide; Cytochalasin B; Cytochrome P-450 Enzyme System; Hydroxycholesterols; Male; Neoplasms, Experimental; Pregnenolone; Rats

1978
A Leydig cell tumour: a model for the study of lutropin action.
    Biochimica et biophysica acta, 1979, Mar-22, Volume: 583, Issue:3

    Topics: Animals; Cyclic AMP; Leydig Cell Tumor; Leydig Cells; Luteinizing Hormone; Male; Models, Biological; Neoplasm Proteins; Neoplasms, Experimental; Pregnenolone; Protein Kinases; Rats; Testicular Neoplasms; Testosterone

1979
Steroidogenesis in isolated cells and mitochondria of rat Snell adrenocortical carcinoma 494.
    Endocrinology, 1979, Volume: 105, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Animals; Carcinoma; Corticosterone; Humans; Hydroxycholesterols; Kinetics; Lipoproteins, HDL; Lipoproteins, LDL; Male; Mitochondria; Neoplasms, Experimental; Pregnenolone; Rats; Steroids

1979
Steroidogenesis from de-novo synthesized cholesterol in isolated cells of the rat Snell adrenocortical carcinoma 494 [proceedings].
    The Journal of endocrinology, 1979, Volume: 81, Issue:2

    Topics: Adrenal Cortex Neoplasms; Animals; Cell Separation; Cholesterol; In Vitro Techniques; Neoplasms, Experimental; Pregnenolone; Rats

1979
Histologic variation among experimental tumors of common origin: relationships to viral p21 expression and to tumor-derived extracellular matrix.
    International journal of cancer, 1990, Oct-15, Volume: 46, Issue:4

    Topics: Adrenal Glands; Animals; Biomarkers, Tumor; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Collagen; Electrophoresis, Polyacrylamide Gel; Extracellular Matrix; Gene Expression Regulation, Neoplastic; Neoplasms, Experimental; Oncogene Protein p21(ras); Phenotype; Pregnenolone; Rats; Rats, Inbred F344

1990
Potential tumor- or organ-imaging agents. 28. Radioiodinated esters of cholesterol and pregnenolone.
    Steroids, 1987, Volume: 49, Issue:6

    Topics: Animals; Biological Transport, Active; Cholesterol Esters; Esters; Female; Iodine Radioisotopes; Neoplasms, Experimental; Pregnenolone; Radionuclide Imaging; Rats; Structure-Activity Relationship; Tissue Distribution

1987
Conversion of dehydroepiandrosterone, pregnenolone, and progesterone by interstitial cell tumor tissue.
    Cancer research, 1970, Volume: 30, Issue:3

    Topics: Androstanes; Animals; Carbon Isotopes; Chromatography; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Female; Leydig Cell Tumor; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Pregnenolone; Progesterone; Testosterone; Tritium

1970
Metabolism of C 19 steroids by homogenates of normal rat and mouse adrenal tissue, and of the Snell transplantable rat adrenocortical tumour 494.
    The Journal of endocrinology, 1972, Volume: 52, Issue:1

    Topics: Adrenal Gland Neoplasms; Adrenal Glands; Androstanes; Androsterone; Animals; Carbon Isotopes; Cholesterol; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; In Vitro Techniques; Neoplasms, Experimental; Pregnenolone; Rats; Tritium

1972
Metabolism of C 19 -steroids by homogenates of normal rat and mouse adrenal tissue and of the Snell transplantable rat adrenocortical tumour 494.
    The Biochemical journal, 1972, Volume: 126, Issue:1

    Topics: Adrenal Gland Neoplasms; Adrenal Glands; Androstanes; Androsterone; Animals; Carbon Isotopes; Cholesterol; Dehydroepiandrosterone; Etiocholanolone; In Vitro Techniques; Ketones; Mice; Neoplasms, Experimental; Pregnenolone; Rats; Steroids; Tritium

1972
Steroid hormone formation by the rat ovary. IV. Formation of steroids from acetate-1-14C by neoplastic ovarian tissue.
    Acta endocrinologica, 1967, Volume: 54, Issue:3

    Topics: Acetates; Animals; Chromatography, Thin Layer; Female; Granulosa Cell Tumor; Neoplasm Transplantation; Neoplasms, Experimental; Ovarian Neoplasms; Pregnenolone; Radioisotope Dilution Technique; Rats; Spleen; Thecoma

1967
Metabolism of steroid hormones in adrenal cortex tumor cultures.
    Endocrinology, 1967, Volume: 81, Issue:4

    Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Chromatography, Thin Layer; Culture Techniques; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Infrared Rays; Kinetics; Mice; Neoplasms, Experimental; Pregnenolone; Spectrophotometry; Steroids; Tritium

1967
In vivo and in vitro studies of steroid production by a luteoma and an adrenal cortical carcinoma in mice.
    Endocrinology, 1969, Volume: 84, Issue:5

    Topics: 17-Hydroxycorticosteroids; Adrenal Gland Neoplasms; Adrenal Insufficiency; Adrenalectomy; Androstanes; Animals; Atrophy; Carbon Isotopes; Carcinoma; Castration; Chromatography; Desoxycorticosterone; Female; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Ovarian Neoplasms; Ovary; Pregnenolone; Progesterone; Testosterone; Thecoma; Tritium

1969
Phenotypically variant adrenal tumor cell cultures with biochemical lesions in the ACTH-stimulated steroidogenic pathway.
    Journal of cellular physiology, 1969, Volume: 74, Issue:2

    Topics: Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Animals; Antigens; Cell Line; Chromatography, Thin Layer; Clone Cells; Complement Fixation Tests; Culture Techniques; Cyclic AMP; Karyotyping; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Pregnanediol; Pregnenolone; Steroids

1969
Adrenal cells in tissue culture. VII. The effect of inhibitors of protein synthesis on steroidogenesis and glycolysis.
    Endocrinology, 1970, Volume: 87, Issue:5

    Topics: Acetates; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Animals; Carbon Isotopes; Cell-Free System; Cholesterol; Culture Techniques; Cycloheximide; Dactinomycin; Depression, Chemical; Glycolysis; Leucine; Lysine; Mice; Neoplasm Proteins; Neoplasms, Experimental; Pregnenolone; Puromycin; RNA, Neoplasm; Tritium; Uridine

1970
Ultrastructural studies and metabolic regulation of isolated adrenocortical carcinoma cells of rat.
    Cancer research, 1972, Volume: 32, Issue:4

    Topics: Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Animals; Carcinoma; Chromatography, Thin Layer; Corticosterone; Cortisone; Cyclic AMP; Cyclic GMP; Depression, Chemical; In Vitro Techniques; Microscopy, Electron; Neoplasms, Experimental; Pregnenolone; Progesterone; Rats; Tritium

1972
Metabolic regulation and adenyl cyclase activity of adrenocortical carcinoma cultured cells.
    Cancer research, 1974, Volume: 34, Issue:6

    Topics: Adenylyl Cyclases; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Animals; Cell Fractionation; Cell Membrane; Cell Nucleus; Cells, Cultured; Cholesterol; Corticosterone; Cyclic AMP; Desoxycorticosterone; Epinephrine; Mitochondria; Neoplasms, Experimental; Pregnenolone; Rats

1974
Adrenal cells in tissue culture. 3. Effect of adrenocorticotropin and 3',5'-cyclic adenosine monophosphate on 11 beta-hydroxylase and other steroidogenic enzymes.
    Biochemistry, 1969, Volume: 8, Issue:5

    Topics: Adenine Nucleotides; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Animals; Calcium; Carbon Isotopes; Citrates; Clone Cells; Culture Techniques; Cyclic AMP; Hydroxysteroid Dehydrogenases; Mice; Mitochondria; Mixed Function Oxygenases; NADP; Neoplasms, Experimental; Pregnanes; Pregnenolone; Progesterone; Steroids; Sterols; Stimulation, Chemical; Time Factors; Tritium

1969
Steroid biosynthesis in vitro by transplantable interstitial cell tumor of mice. 3. Metabolism of pregnenolone in the cultured tumor cell.
    Endocrinology, 1972, Volume: 90, Issue:1

    Topics: Animals; Carbon Isotopes; Cell Line; Hydroxysteroid Dehydrogenases; Leydig Cell Tumor; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Pregnanes; Pregnenolone; Sterols; Testis; Transplantation, Homologous; Tritium

1972
Steroid biosynthesis in vitro by transplantable interstitial cell tumor of mice. I. Identification and quantitative determination of the metabolites and intracellular distributon of the enzymes related to testosterone formation.
    Endocrinology, 1968, Volume: 83, Issue:4

    Topics: Animals; Carbon Isotopes; Chromatography, Thin Layer; Crystallization; Desoxycorticosterone; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Leydig Cell Tumor; Lyases; Male; Mice; Mixed Function Oxygenases; Neoplasm Transplantation; Neoplasms, Experimental; Pregnenolone; Progesterone; Testicular Neoplasms; Testosterone

1968