Page last updated: 2024-08-20

pregnenolone and Cognition Disorders

pregnenolone has been researched along with Cognition Disorders in 5 studies

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (20.00)	18.2507
2000's	1 (20.00)	29.6817
2010's	3 (60.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barbero, JD; Bioque, M; Cobo, J; García-Rizo, C; González-Rodríguez, A; Huerta-Ramos, E; Labad, J; Monreal, JA; Soria, V; Tost, M; Usall, J	1
Bradford, DW; Buchanan, RW; Dunn, L; Hamer, RM; Keefe, RS; Kilts, JD; Leimone, LA; Lieberman, JA; Marx, CE; Morrow, AL; Naylor, JC; Payne, VM; Porcu, P; Savitz, AJ; Shampine, LJ; Strauss, JL	1
Brown, ES; Carmody, TJ; Osuji, IJ; Vera-Bolaños, E	1
Caron, MG; Chang, CC; Marx, CE; Wetsel, WC; Wong, P; Zhang, X	1
Akhondzadeh, S; Stone, TW	1

Reviews

1 review(s) available for pregnenolone and Cognition Disorders

Article	Year
Targeting hypothalamic-pituitary-adrenal axis hormones and sex steroids for improving cognition in major mood disorders and schizophrenia: a systematic review and narrative synthesis. Psychoneuroendocrinology, 2018, Volume: 93 Topics: Affective Disorders, Psychotic; Bipolar Disorder; Cognition Disorders; Cognitive Dysfunction; Depressive Disorder, Major; Female; Gonadal Steroid Hormones; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Mifepristone; Mood Disorders; Pituitary-Adrenal System; Pregnenolone; Raloxifene Hydrochloride; Schizophrenia	2018

Article

Year

Targeting hypothalamic-pituitary-adrenal axis hormones and sex steroids for improving cognition in major mood disorders and schizophrenia: a systematic review and narrative synthesis.

Psychoneuroendocrinology, 2018, Volume: 93

Topics: Affective Disorders, Psychotic; Bipolar Disorder; Cognition Disorders; Cognitive Dysfunction; Depressive Disorder, Major; Female; Gonadal Steroid Hormones; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Mifepristone; Mood Disorders; Pituitary-Adrenal System; Pregnenolone; Raloxifene Hydrochloride; Schizophrenia

2018

Trials

2 trial(s) available for pregnenolone and Cognition Disorders

Article	Year
Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:8 Topics: Adult; Aged; Brain; Brain Chemistry; Cognition Disorders; Double-Blind Method; Female; Humans; Male; Memory Disorders; Middle Aged; Neuropsychological Tests; Nootropic Agents; Pilot Projects; Placebos; Pregnanolone; Pregnenolone; Schizophrenia; Treatment Outcome; Up-Regulation	2009
Pregnenolone for cognition and mood in dual diagnosis patients. Psychiatry research, 2010, Jul-30, Volume: 178, Issue:2 Topics: Adult; Analysis of Variance; Cognition Disorders; Diagnosis, Dual (Psychiatry); Female; Humans; Male; Middle Aged; Mood Disorders; Neuropsychological Tests; Pregnenolone; Psychiatric Status Rating Scales; Substance-Related Disorders; Time Factors; Verbal Learning; Young Adult	2010

Article

Year

Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophrenia.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:8

Topics: Adult; Aged; Brain; Brain Chemistry; Cognition Disorders; Double-Blind Method; Female; Humans; Male; Memory Disorders; Middle Aged; Neuropsychological Tests; Nootropic Agents; Pilot Projects; Placebos; Pregnanolone; Pregnenolone; Schizophrenia; Treatment Outcome; Up-Regulation

2009

Pregnenolone for cognition and mood in dual diagnosis patients.

Psychiatry research, 2010, Jul-30, Volume: 178, Issue:2

Topics: Adult; Analysis of Variance; Cognition Disorders; Diagnosis, Dual (Psychiatry); Female; Humans; Male; Middle Aged; Mood Disorders; Neuropsychological Tests; Pregnenolone; Psychiatric Status Rating Scales; Substance-Related Disorders; Time Factors; Verbal Learning; Young Adult

2010

Other Studies

2 other study(ies) available for pregnenolone and Cognition Disorders

Article	Year
Pregnenolone rescues schizophrenia-like behavior in dopamine transporter knockout mice. PloS one, 2012, Volume: 7, Issue:12 Topics: Animals; Behavior, Animal; Cognition Disorders; Dopamine Plasma Membrane Transport Proteins; Humans; Mice; Mice, Knockout; Motor Activity; Pregnenolone; Receptors, GABA-A; Schizophrenia	2012
Potentiation of muscimol-induced long-term depression by benzodiazepines and prevention or reversal by pregnenolone sulfate. Pharmacological research, 1998, Volume: 38, Issue:6 Topics: Amnesia; Animals; Barbiturates; Benzodiazepines; Cognition Disorders; Depression; Diazepam; Drug Synergism; Hippocampus; In Vitro Techniques; Male; Muscimol; Pentobarbital; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Time Factors	1998

Article

Year

Pregnenolone rescues schizophrenia-like behavior in dopamine transporter knockout mice.

PloS one, 2012, Volume: 7, Issue:12

Topics: Animals; Behavior, Animal; Cognition Disorders; Dopamine Plasma Membrane Transport Proteins; Humans; Mice; Mice, Knockout; Motor Activity; Pregnenolone; Receptors, GABA-A; Schizophrenia

2012

Potentiation of muscimol-induced long-term depression by benzodiazepines and prevention or reversal by pregnenolone sulfate.

Pharmacological research, 1998, Volume: 38, Issue:6

Topics: Amnesia; Animals; Barbiturates; Benzodiazepines; Cognition Disorders; Depression; Diazepam; Drug Synergism; Hippocampus; In Vitro Techniques; Male; Muscimol; Pentobarbital; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Time Factors

1998