Page last updated: 2024-08-20

pregnenolone and Cancer of Testis

pregnenolone has been researched along with Cancer of Testis in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199017 (85.00)18.7374
1990's0 (0.00)18.2507
2000's1 (5.00)29.6817
2010's2 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Auchus, RJ; Avila, NA; Elman, MS; Mallappa, A; Marko, J; Merke, DP; Rao, H; Tsodikov, A; Turcu, AF1
Bailey, JL; Enangue Njembele, AN; Tremblay, JJ1
BOMPIANI, A; KAHNT, FW; NEHER, R; ROVERSI, GD1
Cui, LB; Hong, X; Song, L; Wang, XR; Wang, YB; Zhang, ZD1
Bakker, GH; Hoogerbrugge, JW; Rommerts, FF; van der Molen, HJ1
Ascoli, M; Freeman, DA; Sheets, JJ; Vickery, LE1
Huseby, RA; Matsumoto, K; Samuels, LT; Sato, B1
Bakker, CP; Cooke, BA; Janszen, FH; Lindh, LM; van der Molen, HJ; van der Plank, MP; van Driel, MJ1
Hoogerbrugge, JW; Rommerts, FF; Teerds, KJ1
Kramer, RE; Mason, JI; Rainey, WE; Shay, JW1
Rommerts, FF; van Amerongen, A; van Noort, M; Wirtz, KW1
Melner, MH; Puett, D; Zimniski, SJ1
Brandt, ME; Covey, DF; Melner, MH; Puett, D; Zimniski, SJ1
Allison, JE; Bardin, CW; Gumbreck, LG; Schneider, G; Stanley, AJ; Vanha-Perttula, T1
Coupey, S; Jull, JW; McClellan, D1
Neville, AM; Richards, G1
Hurst, L; Jayle, MF; Lacassagne, A1
Iglesias, R; Irusta, O; Van Houtte, I; Wassermann, GF1
Inano, H; Machino, A; Tamaoki, BI; Tsubura, Y1
Engel, LL; Lanman, G; Scully, RE; Villee, DB1

Other Studies

20 other study(ies) available for pregnenolone and Cancer of Testis

ArticleYear
11-Oxygenated Androgens Are Biomarkers of Adrenal Volume and Testicular Adrenal Rest Tumors in 21-Hydroxylase Deficiency.
    The Journal of clinical endocrinology and metabolism, 2017, 08-01, Volume: 102, Issue:8

    Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenal Rest Tumor; Adult; Age Determination by Skeleton; Aged; Androgens; Androstenedione; Androstenes; Child; Child, Preschool; Cortodoxone; Cross-Sectional Studies; Female; Hirsutism; Humans; Hydroxytestosterones; Male; Menstruation Disturbances; Middle Aged; Organ Size; Pregnenolone; Testicular Neoplasms; Testosterone; Young Adult

2017
In vitro exposure of Leydig cells to an environmentally relevant mixture of organochlorines represses early steps of steroidogenesis.
    Biology of reproduction, 2014, Volume: 90, Issue:6

    Topics: Animals; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Cyclic AMP; Endocrine Disruptors; Environmental Pollutants; Hydrocarbons, Chlorinated; Hydroxycholesterols; Leydig Cell Tumor; Leydig Cells; Male; Mice; Phosphoproteins; Pregnenolone; Progesterone; Steroids; Testicular Neoplasms

2014
STEROID TRANSFORMATIONS IN VITRO BY TESTICULAR TISSUE FROM TWO CASES OF TESTICULAR FEMINISATION.
    Acta endocrinologica, 1965, Volume: 49

    Topics: 17-alpha-Hydroxypregnenolone; Androgen-Insensitivity Syndrome; Androgens; Chromatography; Cryptorchidism; Dehydroepiandrosterone; Disorders of Sex Development; Humans; In Vitro Techniques; Male; Metabolism; Pregnenolone; Progesterone; Steroids; Testicular Neoplasms; Testis; Testosterone

1965
Monobutyl phthalate inhibits steroidogenesis by downregulating steroidogenic acute regulatory protein expression in mouse Leydig tumor cells (MLTC-1).
    Journal of toxicology and environmental health. Part A, 2007, Volume: 70, Issue:11

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Line, Tumor; Cell Survival; Cholera Toxin; Chorionic Gonadotropin; Cyclic AMP; DNA Replication; Dose-Response Relationship, Drug; Down-Regulation; Drug Combinations; Endocrine Disruptors; Humans; Hydroxycholesterols; Leydig Cell Tumor; Male; Mice; Mitochondria; Phosphoproteins; Phthalic Acids; Pregnenolone; Progesterone; RNA, Messenger; Testicular Neoplasms

2007
Lutropin-dependent protein phosphorylation and steroidogenesis in rat tumour Leydig cells.
    The Biochemical journal, 1981, Aug-15, Volume: 198, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; In Vitro Techniques; Kinetics; Leydig Cells; Luteinizing Hormone; Male; Phosphorylation; Pregnenolone; Proteins; Rats; Rats, Inbred Strains; Stimulation, Chemical; Subcellular Fractions; Testicular Neoplasms

1981
Inhibition of steroidogenesis in cultured Leydig tumor cells by 22-amino-23,24-bisnor-5-cholen-3 beta-O1 and (20R) 20-phenyl-5-pregnene-3 beta,20-diol.
    Endocrinology, 1983, Volume: 113, Issue:1

    Topics: Aminoglutethimide; Animals; Cattle; Cholesterol; Chorionic Gonadotropin; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Leydig Cell Tumor; Male; Pregnenes; Pregnenolone; Progesterone; Testicular Neoplasms; Time Factors

1983
Molecular nature of interaction of steroids with biomembranes related to androgen biosynthesis.
    Journal of steroid biochemistry, 1979, Volume: 11, Issue:4

    Topics: 3-Hydroxysteroid Dehydrogenases; Androgens; Animals; Cryptorchidism; Cytosol; Endoplasmic Reticulum; Intracellular Membranes; Leydig Cell Tumor; Magnesium; Male; Mice; Mitochondria; Pregnenolone; Progesterone; Receptors, Steroid; Testicular Neoplasms

1979
A Leydig cell tumour: a model for the study of lutropin action.
    Biochimica et biophysica acta, 1979, Mar-22, Volume: 583, Issue:3

    Topics: Animals; Cyclic AMP; Leydig Cell Tumor; Leydig Cells; Luteinizing Hormone; Male; Models, Biological; Neoplasm Proteins; Neoplasms, Experimental; Pregnenolone; Protein Kinases; Rats; Testicular Neoplasms; Testosterone

1979
In vitro effects of ethylene-dimethane sulfonate (EDS) on Leydig cells: inhibition of steroid production and cytotoxic effects are dependent on species and age of rat.
    Molecular and cellular endocrinology, 1988, Volume: 55, Issue:1

    Topics: Adenosine Triphosphate; Aging; Alkylating Agents; Animals; Cells, Cultured; Hydroxycholesterols; Leydig Cell Tumor; Leydig Cells; Liver; Luteinizing Hormone; Male; Mesylates; Mice; Pregnenolone; Proteins; Rats; Sertoli Cells; Sexual Maturation; Species Specificity; Testicular Neoplasms; Testis

1988
The effects of taxol, a microtubule-stabilizing drug, on steroidogenic cells.
    Journal of cellular physiology, 1985, Volume: 123, Issue:1

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Alkaloids; Animals; Bucladesine; Cattle; Cell Line; Cholesterol; Leydig Cells; Male; Mice; Microtubules; Mitochondria; Paclitaxel; Pregnenolone; Progesterone; Steroids; Testicular Neoplasms

1985
Intracellular redistribution of SCP2 in Leydig cells after hormonal stimulation may contribute to increased pregnenolone production.
    Biochemical and biophysical research communications, 1988, Jul-15, Volume: 154, Issue:1

    Topics: Animals; Carrier Proteins; Cell Line; Leydig Cell Tumor; Leydig Cells; Luteinizing Hormone; Male; Mitochondria; Plant Proteins; Pregnenolone; Sterols; Subcellular Fractions; Testicular Neoplasms

1988
Induction of an estrogen-dependent early steroidogenic lesion in murine Leydig tumor cells.
    Endocrinology, 1985, Volume: 116, Issue:6

    Topics: Animals; Cells, Cultured; Chorionic Gonadotropin; Estradiol; Estrogens; Leydig Cell Tumor; Male; Mice; Mice, Inbred C57BL; Neoplasms, Hormone-Dependent; Pregnenolone; Progesterone; Receptors, Estrogen; Steroids; Testicular Neoplasms

1985
Inhibition of Leydig tumor cell steroidogenesis by 10-propargylestr-4-ene-3,17-dione, an irreversible aromatase inhibitor.
    Cancer research, 1985, Volume: 45, Issue:10

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Leydig Cell Tumor; Male; Mice; Mice, Inbred C57BL; Oxidoreductases; Pargyline; Pregnenolone; Progesterone; Testicular Neoplasms; Testosterone

1985
Testicular tumors in the androgen insensitive pseudohermaphrodite rat: histochemistry and steroid metabolism.
    Gynecologic investigation, 1970, Volume: 1, Issue:3

    Topics: Animals; Carbon Isotopes; Chromatography, Thin Layer; Dehydroepiandrosterone; Disease Models, Animal; Disorders of Sex Development; Histocytochemistry; Hydroxysteroid Dehydrogenases; Leydig Cell Tumor; Leydig Cells; Male; Oxidoreductases; Pregnenolone; Rats; Sertoli Cell Tumor; Testicular Neoplasms; Testis; Tritium

1970
Steroid metabolism by an oestrogen-dependent interstitial-cell tumour of a rat testis.
    The Journal of endocrinology, 1973, Volume: 59, Issue:1

    Topics: Androstenedione; Androstenes; Androsterone; Animals; Carbon Radioisotopes; Cholesterol; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Etiocholanolone; In Vitro Techniques; Leydig Cell Tumor; Male; Pregnenolone; Rats; Steroids; Testicular Neoplasms; Testosterone

1973
Steroid metabolism in vitro by an interstitial cell tumour and the attached prepubertal testis.
    The Journal of endocrinology, 1973, Volume: 59, Issue:3

    Topics: Adolescent; Androstenedione; Carbon Radioisotopes; Chromatography, Thin Layer; Dehydroepiandrosterone; Humans; Hydroxyprogesterones; Leydig Cell Tumor; Male; Pregnenolone; Progesterone; Puberty; Steroids; Testicular Neoplasms; Testis; Testosterone; Tritium

1973
[Inhibitory actions of pregnenolone on cancerization of the liver, and favourable to the development of neoplasms of the interstitial gland of the testis, in rats poisoned by para-dimethylaminoazobenzene (DAB)].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1971, Jan-04, Volume: 272, Issue:1

    Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Age Factors; Animals; Body Weight; Carcinoma, Hepatocellular; Hypertrophy; Leydig Cell Tumor; Liver; Liver Neoplasms; Male; Organ Size; p-Dimethylaminoazobenzene; Pregnenolone; Progesterone; Prostate; Protein Deficiency; Rats; Riboflavin Deficiency; Seminal Vesicles; Spermatozoa; Testicular Neoplasms

1971
Steroid biosynthesis by transplantable gonadal tumors of rat.
    Journal of steroid biochemistry, 1973, Volume: 4, Issue:5

    Topics: 17-alpha-Hydroxypregnenolone; Acetates; Androstenedione; Animals; Bucladesine; Carbon Radioisotopes; Cholesterol; Chromatography, Paper; Dehydroepiandrosterone; Estradiol; Estrogens; Estrone; Female; Granulosa Cell Tumor; Hydroxyprogesterones; Luteinizing Hormone; Male; Neoplasm Transplantation; Ovarian Neoplasms; Pregnenolone; Progesterone; Rats; Spectrophotometry, Ultraviolet; Testicular Neoplasms; Testosterone; Transplantation, Homologous; Tritium

1973
Steroid biosynthesis in vitro by transplantable interstitial cell tumor of mice. I. Identification and quantitative determination of the metabolites and intracellular distributon of the enzymes related to testosterone formation.
    Endocrinology, 1968, Volume: 83, Issue:4

    Topics: Animals; Carbon Isotopes; Chromatography, Thin Layer; Crystallization; Desoxycorticosterone; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Leydig Cell Tumor; Lyases; Male; Mice; Mixed Function Oxygenases; Neoplasm Transplantation; Neoplasms, Experimental; Pregnenolone; Progesterone; Testicular Neoplasms; Testosterone

1968
Studies on an interstitial cell tumor of the testis: formation of cortisol-14C from acetate-1-14C1.
    The Journal of clinical endocrinology and metabolism, 1966, Volume: 26, Issue:4

    Topics: Acetates; Androsterone; Autoradiography; Carbon Isotopes; Child, Preschool; Cortisone; Countercurrent Distribution; Hormones; Humans; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Lipids; Male; Pregnenolone; Steroids; Testicular Neoplasms

1966