Page last updated: 2024-08-20

pregnenolone and Breast Cancer

pregnenolone has been researched along with Breast Cancer in 37 studies

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	30 (81.08)	18.7374
1990's	1 (2.70)	18.2507
2000's	1 (2.70)	29.6817
2010's	3 (8.11)	24.3611
2020's	2 (5.41)	2.80

Authors

Authors	Studies
Alqahtani, YS; Alqarni, AO; Alyami, BA; Ejaz, I; Mahnashi, MH; Rashid, U; Sadiq, A; Saeed Jan, M	1
Andreeva, OE; Barysevich, MV; Hurski, AL; Khripach, VA; Laktsevich-Iskryk, MV; Salnikova, DI; Scherbakov, AM; Shchegolev, YY; Sorokin, DV; Zhabinskii, VN	1
Alonso-Diez, A; Caceres, S; de Andres, PJ; Illera, JC; Illera, MJ; Monsalve, B; Peña, L; Reuben, JM; Silvan, G; Woodward, WA	1
Bříza, T; Kejík, Z; Král, V; Králová, J; Martásek, P; Mikula, I; Poučková, P	1
Mehtiev, AR; Misharin, AY; Novikov, RA; Stulov, SV; Timofeev, VP; Tkachev, YV; Zavialova, MG	1
Dumas, N; Falany, CN; Falany, JL; Frost, AR; He, D	1
Deshpande, N; Di Martino, L; Mitchell, I; Tarquini, A	1
Carreau, S; Drosdowsky, MA; Edery, M; Simon, MJ	1
Davis, JC; Duncan, JN; Wade, AP; Walker, S	1
Check, WA	1
Howarth, NM; Potter, BV; Purohit, A; Reed, MJ	1
Deshpande, N	1
Carson, P; Deshpande, N; Di Martino, L; Tarquini, A	1
Carson, P; Deshpande, N; Mitchell, I; O'Higgins, NJ	1
Abul-Hajj, YJ; Iverson, R; Kiang, DT	1
Horino, M; Kakita, K; Matsuki, M; Matsumura, S; Nishida, S; Omukai, Y; Oyama, H; Tanaka, H; Tenku, A	1
Carson, P; Deshpande, N; O'Higgins, NJ	1
Carson, P; Deshipande, N; Ohiggins, N	1
Drife, JO	1
Gunasegaram, R; Kottegoda, SR; Loganath, A; Peh, KL; Ratnam, SS; Thiagaraj, D	1
Bradlow, HL; Fishman, J; Hershcopf, R; Martucci, C	1
James, VH; Jones, DL	1
Bulbrook, RD; Deshpande, N; Doouss, TW; Jensen, V	2
Deshpande, N; Doouss, TW	1
Dao, TL; Libby, PR	2
Anderson, AB; Cameron, EH; Griffiths, K; Jones, D; Jones, T	1
Bulbrook, RD; Carson, P; Deshpande, N; Doouss, TW; Jensen, V	1
Kley, HK; Krüskemper, HL	1
Babin, P; de Giacomoni, P; Payard, J; Saurel, J	1
Nice, E; Williams, K	1
Carson, P; Deshpande, N; O'Higgins, N	1
Brough, AJ; Cash, R; Cohen, MN; Satoh, PS	1
Williams, K	1
Birmingham, MK; De Nicola, AF; Palmer, JD; Ruddick, DW; Traikov, H	1
Adams, JB; Wong, MS	1

Reviews

3 review(s) available for pregnenolone and Breast Cancer

Article	Year
Breast development in puberty. Annals of the New York Academy of Sciences, 1986, Volume: 464 Topics: Adipose Tissue; Adolescent; Adult; Androgens; Breast; Breast Neoplasms; Cell Differentiation; Cell Division; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; DNA Replication; Epithelial Cells; Estradiol; Female; Gonadotropin-Releasing Hormone; Gonadotropins; Humans; Insulin-Like Growth Factor I; Male; Menarche; Menopause; Pregnancy; Pregnancy Trimester, Second; Pregnenolone; Puberty; Risk; Sex Characteristics; Time Factors	1986
16 alpha-hydroxylation of estradiol: a possible risk marker for breast cancer. Annals of the New York Academy of Sciences, 1986, Volume: 464 Topics: Age Factors; Animals; Breast; Breast Neoplasms; Dihydrotestosterone; Estradiol; Estriol; Female; Haplorhini; Humans; Hydroxylation; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Pan troglodytes; Pregnenolone; Progesterone; Rats; Risk; Species Specificity; Steroid 16-alpha-Hydroxylase; Testosterone	1986
[Androgens. Biochemistry, pharmacodynamics and therapeutic use]. Medizinische Klinik, 1973, Mar-09, Volume: 68, Issue:10 Topics: Anabolic Agents; Androgens; Androstenes; Breast Neoplasms; Carrier Proteins; Dehydroepiandrosterone; Female; Humans; Male; Pregnenolone; Testosterone	1973

Trials

1 trial(s) available for pregnenolone and Breast Cancer

Article	Year
Aminoglutethimide (Elipten-Ciba) as an inhibitor of adrenal steroidogenesis: mechanism of action and therapeutic trial. The Journal of clinical endocrinology and metabolism, 1967, Volume: 27, Issue:9 Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Animals; Anticonvulsants; Breast Neoplasms; Child; Cholesterol; Clinical Trials as Topic; Cushing Syndrome; Enzyme Therapy; Enzymes; Epilepsy, Absence; Female; Humans; Lyases; Male; Middle Aged; Neoplasm Metastasis; Pregnenolone; Rats	1967

Article

Year

Aminoglutethimide (Elipten-Ciba) as an inhibitor of adrenal steroidogenesis: mechanism of action and therapeutic trial.

The Journal of clinical endocrinology and metabolism, 1967, Volume: 27, Issue:9

Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Animals; Anticonvulsants; Breast Neoplasms; Child; Cholesterol; Clinical Trials as Topic; Cushing Syndrome; Enzyme Therapy; Enzymes; Epilepsy, Absence; Female; Humans; Lyases; Male; Middle Aged; Neoplasm Metastasis; Pregnenolone; Rats

1967

Other Studies

33 other study(ies) available for pregnenolone and Breast Cancer

Article	Year
Design, synthesis, antiproliferative activity, estrogen receptors binding affinity of C-3 pregnenolone-dihydropyrimidine derivatives for the treatment of breast cancer. Steroids, 2022, Volume: 185 Topics: Breast Neoplasms; Cell Proliferation; Estrogen Receptor alpha; Female; HEK293 Cells; Humans; MCF-7 Cells; Pregnenolone; Receptors, Estrogen	2022
Synthesis and biological activity of 21,22-cyclosteroids and their derivatives. Steroids, 2022, Volume: 188 Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclosteroids; Humans; Imidazoles; Male; Pregnenolone; Receptors, Androgen; Steroids	2022
In vitro and in vivo effect of flutamide on steroid hormone secretion in canine and human inflammatory breast cancer cell lines. Veterinary and comparative oncology, 2018, Volume: 16, Issue:1 Topics: Androstenedione; Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Line, Tumor; Dihydrotestosterone; Dog Diseases; Dogs; Estradiol; Estrone; Female; Flutamide; Gonadal Steroid Hormones; Humans; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Pregnenolone; Progesterone; Testosterone	2018
New method for recognition of sterol signalling molecules: methinium salts as receptors for sulphated steroids. Steroids, 2015, Volume: 94 Topics: Animals; Antineoplastic Agents; Benzothiazoles; Breast Neoplasms; Carbocyanines; Cholesterol Esters; Estrone; Female; Heterocyclic Compounds; Mice, Nude; Pregnenolone; Xenograft Model Antitumor Assays	2015
[17(20)E]- and [17(20)Z]-pregna-5,17(20)-dien-21-oylamides. Facile synthesis and primary evaluation for cancer cells proliferation. Bioorganic & medicinal chemistry letters, 2010, Sep-15, Volume: 20, Issue:18 Topics: Androgens; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Proliferation; Female; Humans; Male; Pregnenolone; Prostatic Neoplasms	2010
Human cytosolic sulfotransferase 2B1: isoform expression, tissue specificity and subcellular localization. The Journal of steroid biochemistry and molecular biology, 2006, Volume: 102, Issue:1-5 Topics: Amino Acid Sequence; Animals; Breast; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cell Nucleus; Cholesterol; Choriocarcinoma; Cloning, Molecular; Cytosol; Dehydroepiandrosterone; Gene Expression Regulation; Humans; Mice; Molecular Sequence Data; Placenta; Pregnenolone; Protein Isoforms; Rats; Sequence Homology, Amino Acid; Skin; Subcellular Fractions; Substrate Specificity; Sulfates; Sulfotransferases; Transcription, Genetic	2006
Hormone synthesis by primary breast carcinomas and prognosis in human breast cancer. Tumori, 1980, Apr-30, Volume: 66, Issue:2 Topics: Androgens; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Female; Humans; Neoplasm Staging; Pregnenolone; Progesterone; Prognosis; Recurrence	1980
In vitro pregnenolone metabolism by mouse adrenal gland: II-Biosynthesis of androgens. Steroids, 1982, Volume: 39, Issue:2 Topics: Adrenal Glands; Androgens; Animals; Breast Neoplasms; Castration; Dehydroepiandrosterone; Female; In Vitro Techniques; Male; Mice; NADP; Pregnenolone; Progesterone; Species Specificity; Testosterone	1982
Short term organ culture of human breast tumour tissue and its application in studies of steroid metabolism. European journal of cancer & clinical oncology, 1981, Volume: 17, Issue:10 Topics: Aromatase; Breast Neoplasms; Cholesterol; Culture Media; Female; Humans; Organ Culture Techniques; Pregnenolone; Steroids; Testosterone; Time Factors	1981
Medical adrenalectomy may replace surgery for advanced breast cancer. JAMA, 1980, Jul-04, Volume: 244, Issue:1 Topics: Adipose Tissue; Adrenal Glands; Adrenalectomy; Aminoglutethimide; Androstenedione; Breast Neoplasms; Cholesterol; Estradiol; Estrogen Antagonists; Female; Humans; Pregnenolone	1980
Inhibition of steroid sulphatase activity by steroidal methylthiophosphonates: potential therapeutic agents in breast cancer. The Journal of steroid biochemistry and molecular biology, 1994, Volume: 48, Issue:5-6 Topics: Antineoplastic Agents; Arylsulfatases; Breast Neoplasms; Cholesterol; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Female; Humans; Microsomes; Placenta; Pregnancy; Pregnenolone; Steryl-Sulfatase; Tumor Cells, Cultured	1994
Hormonal imbalance in breast cancer. Journal of steroid biochemistry, 1975, Volume: 6, Issue:5 Topics: Adrenal Gland Neoplasms; Adrenal Glands; Androgens; Androstenedione; Breast Neoplasms; Cholesterol; Dehydroepiandrosterone; Female; Humans; Hydroxysteroid Dehydrogenases; Lyases; Neoplasm Metastasis; Pregnenolone; Progesterone; Steroid Isomerases	1975
Biogenesis of steroid hormones by human mammary gland in vivo and in vitro. European journal of cancer, 1976, Volume: 12, Issue:4 Topics: Androstenedione; Breast Neoplasms; Cyanoketone; Dehydroepiandrosterone; Female; Humans; In Vitro Techniques; Pregnenolone; Progesterone	1976
Adrenal function in breast cancer: the metabolism of pregnenolone in breast cancer patients. Clinical oncology, 1976, Volume: 2, Issue:3 Topics: Adrenal Cortex Function Tests; Adult; Aged; Breast Neoplasms; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Middle Aged; Neoplasm Metastasis; Pregnenolone; Radioisotopes	1976
Metabolism of pregnenolone by human breast cancer. Evidence for 17 alpha-hydroxylase and 17,20-lyase. Steroids, 1979, Volume: 34, Issue:7 Topics: 17-alpha-Hydroxypregnenolone; Aged; Aldehyde-Lyases; Androstenedione; Breast Neoplasms; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Estradiol; Female; Humans; Hydroxyprogesterones; Menopause; Middle Aged; Pregnenolone; Progesterone; Receptors, Estrogen; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases	1979
Dexamethasone suppressibility of plasma pregnenolone or dehydroepiandrosterone in gonadectomized patients. Steroids, 1979, Volume: 34, Issue:4 Topics: Adrenocorticotropic Hormone; Adult; Aged; Breast Neoplasms; Castration; Dehydroepiandrosterone; Dexamethasone; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Pregnenolone; Prostatic Neoplasms	1979
Proceedings: Pegnenolone metabolism as a prognostic guide in mammary carcinoma. The British journal of surgery, 1975, Volume: 62, Issue:2 Topics: Breast Neoplasms; Female; Humans; Hydrocortisone; Pregnenolone; Prognosis; Tritium	1975
Pregnenolone metabolism in mammary carcinoma. Bulletin de la Societe internationale de chirurgie, 1975, Volume: 34, Issue:6 Topics: Adult; Breast Neoplasms; Female; Humans; Pregnenolone	1975
Steroidogenic expression of delta 5-3 beta-hydroxy pathway of androgen biosynthesis by human breast carcinoma. Annals of the Academy of Medicine, Singapore, 1986, Volume: 15, Issue:1 Topics: 17-alpha-Hydroxypregnenolone; Acetyl Coenzyme A; Adult; Aged; Androgens; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cholesterol; Dehydroepiandrosterone; Female; Humans; In Vitro Techniques; Middle Aged; Models, Chemical; Pregnenolone	1986
The identification, quantification and possible origin of non-polar conjugates in human plasma. Journal of steroid biochemistry, 1985, Volume: 22, Issue:2 Topics: Acne Vulgaris; Adult; Aged; Androstenediol; Breast Neoplasms; Dehydroepiandrosterone; Female; Hirsutism; Humans; Male; Middle Aged; Pregnancy; Pregnenolone; Steroids	1985
In vivo steroidogenesis by the human adrenal gland. Steroids, 1967, Volume: 9, Issue:4 Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Adrenalectomy; Androsterone; Breast Neoplasms; Crystallization; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Pregnenolone; Steroids; Tritium	1967
In vivo perfusion of the human adrenal gland and ovary in patients with mammary cancer. The British journal of surgery, 1968, Volume: 55, Issue:9 Topics: Adrenal Glands; Androgens; Breast Neoplasms; Chromatography, Paper; Dehydroepiandrosterone; Estradiol; Female; Humans; Hydrocortisone; Ovary; Perfusion; Pregnenolone; Progesterone; Testosterone; Tritium	1968
Conjugation of steroid hormones by normal and neoplastic tissues. The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:10 Topics: Adult; Aged; Breast; Breast Neoplasms; Chromatography, Paper; Dehydroepiandrosterone; Desoxycorticosterone; Estradiol; Female; Humans; Hydrogen-Ion Concentration; Liver; Liver Neoplasms; Middle Aged; Nandrolone; Neoplasm Metastasis; Pregnenolone; Steroids; Sulfates; Sulfur Isotopes; Transferases	1968
Conjugation of steroid hormones by breast cancer tissue and selection of patients for adrenalectomy. Surgery, 1969, Volume: 66, Issue:1 Topics: Adrenalectomy; Aged; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estrone; Humans; Liver; Liver Neoplasms; Middle Aged; Neoplasm Metastasis; Pregnenolone; Sulfur Isotopes; Sulfuric Acids; Testosterone	1969
Further studies on the relationship between C19- and C21-steroid synthesis in the human adrenal gland. The Journal of endocrinology, 1969, Volume: 45, Issue:2 Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adenoma; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Androgens; Breast Neoplasms; Carbon Isotopes; Dehydroepiandrosterone; Estrogens; Female; Humans; Hydrocortisone; In Vitro Techniques; Pregnenolone; Testosterone; Transferases; Tritium	1969
Adrenal function in breast cancer: biogenesis of androgens and cortisol by the human adrenal gland in vivo. The Journal of endocrinology, 1970, Volume: 47, Issue:2 Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Glands; Adrenalectomy; Adult; Aged; Androgens; Androstanes; Androsterone; Breast Neoplasms; Carbon Isotopes; Chromatography, Gas; Chromatography, Paper; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Middle Aged; Ovary; Pregnenolone; Progesterone; Radioisotope Dilution Technique; Tritium	1970
[Several steroid derivatives in breast tumors. Histo-enzymological study]. La Nouvelle presse medicale, 1973, Jun-02, Volume: 2, Issue:22 Topics: Biopsy; Breast; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Female; Histocytochemistry; Humans; Oxidoreductases; Pregnenolone	1973
Simultaneous estimation of pregnenolone, 17-hydroxypregnenolone and dehydroepiandrosterone by gas-liquid radiochromatography. Analytical biochemistry, 1974, Volume: 59, Issue:2 Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Adrenalectomy; Breast Neoplasms; Carbon Radioisotopes; Chromatography, Gas; Dehydroepiandrosterone; Evaluation Studies as Topic; Female; Humans; Methods; Microsomes; Pregnenolone; Tritium	1974
Proceedings: Pregnenolone metabolism in patients with carcinoma. British journal of cancer, 1974, Volume: 30, Issue:2 Topics: Breast Neoplasms; Carcinoma; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Metabolic Clearance Rate; Pregnenolone; Prognosis	1974
The effect of NADPH on steroidogenesis by the human adrenal gland in vivo. The Journal of endocrinology, 1969, Volume: 43, Issue:1 Topics: Adrenal Glands; Adrenalectomy; Breast Neoplasms; Castration; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; NADP; Neoplasm Metastasis; Pregnenolone; Tritium	1969
Defective steroidal synthesis by adrenal tissue: the control of gene expression causing loss of active steroidogenic enzymes. Acta endocrinologica, 1974, Volume: 77, Issue:2 Topics: Adrenal Glands; Animals; Breast Neoplasms; Carbon Radioisotopes; Centrifugation, Density Gradient; Chromatography, Thin Layer; Female; Genes; Humans; Hydroxysteroid Dehydrogenases; Hyperplasia; Male; Microsomes, Liver; Mitochondria, Liver; Pregnenolone; Progesterone; Rats; Ribonucleases; RNA; Steroid Hydroxylases; Tritium; Virilism	1974
18-hydroxylation by human adrenal tissue in vitro. The Journal of clinical endocrinology and metabolism, 1970, Volume: 30, Issue:3 Topics: Adrenal Glands; Aldosterone; Breast Neoplasms; Carbon Isotopes; Corticosterone; Crystallization; Desoxycorticosterone; Glucocorticoids; Humans; Hyperaldosteronism; In Vitro Techniques; Mixed Function Oxygenases; Pregnenolone; Progesterone	1970
Desmolase activity of normal and malignant human breast tissue. The Journal of endocrinology, 1969, Volume: 44, Issue:1 Topics: Breast; Breast Neoplasms; Carbon Isotopes; Cholesterol; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Lyases; Pregnenolone; Tissue Extracts	1969