Page last updated: 2024-08-20

pregnenolone and Anxiety

pregnenolone has been researched along with Anxiety in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's8 (61.54)29.6817
2010's1 (7.69)24.3611
2020's3 (23.08)2.80

Authors

AuthorsStudies
Charron, L; Fogelman, N; Hermes, G; Milivojevic, V; Sinha, R1
Fogelman, N; Hermes, G; Milivojevic, V; Simpson, C; Sinha, R; Sullivan, L; Tiber, J1
Deligiannidis, KM; Dubuke, ML; Kroll-Desrosiers, AR; Shaffer, SA; Tan, Y1
Darbra, S; Martín-García, E; Pallarés, M1
Martín-García, E; Pallarés, M2
Goyal, R; Kumar, A; Prakash, A1
Darbra, S; Mòdol, L; Pallarès, M1
Biggio, G; Brambilla, F; Gerra, G; Pisu, MG; Purdy, RH; Serra, M; Zaimovich, A1
Cruz, ND; Fortis, A; González, L; Jorge, JC1
Melchior, CL; Ritzmann, RF1
Biggio, G; Littera, M; Papi, G; Pisu, MG; Purdy, RH; Sanna, E; Serra, M; Tuveri, F; Usala, L1
Bicíková, M; Hampl, R; Hill, M; Krausová, Z; Tallová, J1

Trials

2 trial(s) available for pregnenolone and Anxiety

ArticleYear
Pregnenolone Reduces Stress-Induced Craving, Anxiety, and Autonomic Arousal in Individuals with Cocaine Use Disorder.
    Biomolecules, 2022, 10-29, Volume: 12, Issue:11

    Topics: Anxiety; Arousal; Cocaine; Craving; Female; Humans; Male; Neurosteroids; Pregnenolone; Stress, Psychological

2022
Pregnenolone effects on provoked alcohol craving, anxiety, HPA axis, and autonomic arousal in individuals with alcohol use disorder.
    Psychopharmacology, 2023, Volume: 240, Issue:1

    Topics: Alcohol Drinking; Alcoholism; Anxiety; Arousal; Craving; Cues; Ethanol; Humans; Hypothalamo-Hypophyseal System; Neurosteroids; Pituitary-Adrenal System; Pregnenolone; Recurrence

2023

Other Studies

11 other study(ies) available for pregnenolone and Anxiety

ArticleYear
Longitudinal proneuroactive and neuroactive steroid profiles in medication-free women with, without and at-risk for perinatal depression: A liquid chromatography-tandem mass spectrometry analysis.
    Psychoneuroendocrinology, 2020, Volume: 121

    Topics: 20-alpha-Dihydroprogesterone; Adult; Anxiety; Chromatography, Liquid; Depression; Depression, Postpartum; Depressive Disorder; Desoxycorticosterone; Female; Humans; Longitudinal Studies; Neurosteroids; Parturition; Pregnancy; Pregnanolone; Pregnenolone; Prenatal Care; Progesterone; Prospective Studies; Risk Factors; Tandem Mass Spectrometry

2020
Neonatal finasteride induces anxiogenic-like profile and deteriorates passive avoidance in adulthood after intrahippocampal neurosteroid administration.
    Neuroscience, 2008, Jul-17, Volume: 154, Issue:4

    Topics: Animals; Animals, Newborn; Anxiety; Avoidance Learning; Enzyme Inhibitors; Finasteride; Gonadal Steroid Hormones; Hippocampus; Injections, Intraventricular; Male; Maze Learning; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Receptors, GABA-A

2008
A post-training intrahippocampal anxiogenic dose of the neurosteroid pregnenolone sulfate impairs passive avoidance retention.
    Experimental brain research, 2008, Volume: 191, Issue:2

    Topics: Animals; Anxiety; Avoidance Learning; Electric Stimulation; Hippocampus; Learning; Male; Memory; Neuropsychological Tests; Pregnenolone; Rats; Rats, Wistar; Reinforcement, Psychology; Stress, Psychological; Teaching

2008
Possible GABAergic mechanism in the protective effect of allopregnenolone against immobilization stress.
    European journal of pharmacology, 2009, Jan-14, Volume: 602, Issue:2-3

    Topics: Animals; Anxiety; Behavior, Animal; GABA Agents; Immobilization; Mice; Muscimol; Oxidative Stress; Picrotoxin; Pregnenolone; Stereoisomerism; Stress, Psychological

2009
Neurosteroids infusion into the CA1 hippocampal region on exploration, anxiety-like behaviour and aversive learning.
    Behavioural brain research, 2011, Sep-12, Volume: 222, Issue:1

    Topics: Animals; Anxiety; Avoidance Learning; Body Weight; CA1 Region, Hippocampal; Disease Models, Animal; Exploratory Behavior; Male; Maze Learning; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Statistics, Nonparametric

2011
Plasma concentrations of anxiolytic neurosteroids in men with normal anxiety scores: a correlation analysis.
    Neuropsychobiology, 2004, Volume: 50, Issue:1

    Topics: Adult; Anxiety; Desoxycorticosterone; Humans; Male; Pregnanolone; Pregnenolone; Progesterone; Psychiatric Status Rating Scales; Reference Values

2004
Sex-specific modulation of anxiety and locomotion after neonatal exposure to pregnenolone sulfate.
    Physiology & behavior, 2005, Jan-17, Volume: 83, Issue:5

    Topics: Animals; Animals, Newborn; Anxiety; Body Weight; Estrous Cycle; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Gonadal Steroid Hormones; Male; Motor Activity; Organ Size; Pregnenolone; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Testis; Vagina

2005
Intrahippocampal nicotine and neurosteroids effects on the anxiety-like behaviour in voluntary and chronic alcohol-drinking rats.
    Behavioural brain research, 2005, Oct-14, Volume: 164, Issue:1

    Topics: Administration, Oral; Alcohol Drinking; Animals; Anti-Anxiety Agents; Anxiety; Drug Interactions; Ethanol; Exploratory Behavior; GABA Agents; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Hippocampus; Male; Microinjections; Motor Activity; Nicotine; Nicotinic Agonists; Pregnanolone; Pregnenolone; Random Allocation; Rats; Rats, Wistar; Receptors, GABA-A; Self Medication

2005
Pregnenolone and pregnenolone sulfate, alone and with ethanol, in mice on the plus-maze.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 48, Issue:4

    Topics: Animals; Anxiety; Behavior, Animal; Dose-Response Relationship, Drug; Ethanol; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred C57BL; Motor Activity; Pregnenolone; Stress, Psychological; Sulfates

1994
Social isolation-induced decreases in both the abundance of neuroactive steroids and GABA(A) receptor function in rat brain.
    Journal of neurochemistry, 2000, Volume: 75, Issue:2

    Topics: Animals; Anxiety; Brain; Cerebral Cortex; Conflict, Psychological; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Electroshock; Female; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Oocytes; Pregnanolone; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Social Isolation; Steroids; Synaptosomes; Time Factors; Xenopus laevis

2000
Serum concentrations of some neuroactive steroids in women suffering from mixed anxiety-depressive disorder.
    Neurochemical research, 2000, Volume: 25, Issue:12

    Topics: 17-alpha-Hydroxypregnenolone; Adult; Anxiety; Depressive Disorder; Female; Follicular Phase; Humans; Menstrual Cycle; Middle Aged; Osmolar Concentration; Pregnenolone; Steroids

2000