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pregnenolone and Alzheimer Disease

pregnenolone has been researched along with Alzheimer Disease in 9 studies

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	8 (88.89)	29.6817
2010's	1 (11.11)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chang, F; Chen, L; Sokabe, M; Xie, G; Xu, B; Yang, R	1
Akwa, Y; Baulieu, EE; David, JP; Delacourte, A; Eychenne, B; Liere, P; Pianos, A; Sazdovitch, V; Schumacher, M; Weill-Engerer, S	1
Kamei, H; Manh Tran, H; Maurice, T; Nabeshima, T; Nagai, T; Noda, Y; Roman, FJ; Romieu, P; Urani, A; Yamada, K	1
Bicíková, M; Hampl, R; Havlíková, H; Hill, M; Jirák, R; Rípová, D; Tallová, J	1
Baulieu, EE; David, S; Duchossoy, Y; Fellous, A; Fontaine-Lenoir, V; Robel, P	1
Blazer, DG; Butterfield, MI; Ervin, JF; Hulette, CM; Lieberman, JA; Marx, CE; Massing, MW; Shampine, LJ; Steffens, DC; Stevens, RD; Trost, WT	1
Eckert, A; Mensah-Nyagan, AG; Meyer, L; Patte-Mensah, C; Schaeffer, V	1
Blazer, DG; Calhoun, PS; Calnaido, RP; Ervin, JF; Hulette, CM; Kilts, JD; Lieberman, JA; Madison, RD; Marx, CE; Massing, MW; Naylor, JC; Payne, VM; Shampine, LJ; Steffens, DC; Strauss, JL	1
Abrous, DN; Le Moal, M; Mayo, W	1

Reviews

1 review(s) available for pregnenolone and Alzheimer Disease

Article	Year
MAPREG: toward a novel approach of neuroprotection and treatment of Alzheimer's disease. Journal of molecular neuroscience : MN, 2004, Volume: 24, Issue:1 Topics: Alzheimer Disease; Animals; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Drug Industry; Humans; Microtubule-Associated Proteins; Microtubules; Neuroprotective Agents; Pregnenolone	2004

Other Studies

8 other study(ies) available for pregnenolone and Alzheimer Disease

Article	Year
Neurosteroid PREGS protects neurite growth and survival of newborn neurons in the hippocampal dentate gyrus of APPswe/PS1dE9 mice. Current Alzheimer research, 2012, Volume: 9, Issue:3 Topics: Alzheimer Disease; Animals; Animals, Newborn; Dehydroepiandrosterone; Dentate Gyrus; Disease Models, Animal; Humans; Male; Mice; Mice, Transgenic; Neural Stem Cells; Neurites; Neurogenesis; Pregnenolone	2012
Neurosteroid quantification in human brain regions: comparison between Alzheimer's and nondemented patients. The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:11 Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amygdala; Amyloid beta-Peptides; Brain Chemistry; Cerebellum; Corpus Striatum; Dehydroepiandrosterone Sulfate; Female; Frontal Lobe; Gas Chromatography-Mass Spectrometry; Hippocampus; Humans; Hypothalamus; Male; Pregnanolone; Pregnenolone; Progesterone; Protein Structure, Secondary; Steroids; tau Proteins	2002
Enhanced antidepressant efficacy of sigma1 receptor agonists in rats after chronic intracerebroventricular infusion of beta-amyloid-(1-40) protein. European journal of pharmacology, 2004, Feb-20, Volume: 486, Issue:2 Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antidepressive Agents; Brain; Cinnamates; Conditioning, Psychological; Cyclopropanes; Dehydroepiandrosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Fear; Injections, Intraventricular; Male; Peptide Fragments; Phenazocine; Pregnenolone; Progesterone; Rats; Rats, Wistar; Receptors, sigma; Sigma-1 Receptor; Stress, Psychological	2004
Plasma levels of 7-hydroxylated dehydroepiandrosterone (DHEA) metabolites and selected amino-thiols as discriminatory tools of Alzheimer's disease and vascular dementia. Clinical chemistry and laboratory medicine, 2004, Volume: 42, Issue:5 Topics: 17-alpha-Hydroxypregnenolone; Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Chromatography, High Pressure Liquid; Cysteine; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dementia, Vascular; Dipeptides; Female; Glutathione; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Predictive Value of Tests; Pregnenolone; Radioimmunoassay; Sensitivity and Specificity; Sex Factors; Statistics, Nonparametric; Sulfhydryl Compounds	2004
The neurosteroid allopregnanolone is reduced in prefrontal cortex in Alzheimer's disease. Biological psychiatry, 2006, Dec-15, Volume: 60, Issue:12 Topics: Aged; Alzheimer Disease; Biomarkers; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Disease Progression; Gas Chromatography-Mass Spectrometry; Humans; Male; Prefrontal Cortex; Pregnanolone; Pregnenolone	2006
Dose-dependent and sequence-sensitive effects of amyloid-beta peptide on neurosteroidogenesis in human neuroblastoma cells. Neurochemistry international, 2008, Volume: 52, Issue:6 Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Brain; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Estrogens; Humans; Neuroblastoma; Neurons; Peptide Fragments; Pregnenolone; Progesterone; Steroids	2008
Cerebrospinal fluid dehydroepiandrosterone levels are correlated with brain dehydroepiandrosterone levels, elevated in Alzheimer's disease, and related to neuropathological disease stage. The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:8 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Dehydroepiandrosterone; Humans; Pregnenolone; Temporal Lobe	2008
Pregnenolone sulfate and aging of cognitive functions: behavioral, neurochemical, and morphological investigations. Hormones and behavior, 2001, Volume: 40, Issue:2 Topics: Aging; Alzheimer Disease; Animals; Antimetabolites; Behavior, Animal; Brain; Brain Chemistry; Bromodeoxyuridine; Cell Division; Cognition; Humans; Pregnenolone; Rats; Receptors, GABA-A; Sleep	2001