Page last updated: 2024-08-20

pregnenolone and Alcoholism

pregnenolone has been researched along with Alcoholism in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's1 (10.00)18.2507
2000's3 (30.00)29.6817
2010's4 (40.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Fogelman, N; Hermes, G; Milivojevic, V; Simpson, C; Sinha, R; Sullivan, L; Tiber, J1
Tomaselli, G; Vallée, M1
Levin, ED; Rezvani, AH1
Auriola, S; Häkkinen, MR; Kärkkäinen, O; Kautiainen, H; Storvik, M; Tiihonen, J1
Besheer, J; Hodge, CW; Lindsay, TG; Morrow, AL; O'Buckley, TK1
Barbosa, AD; Morato, GS1
Cerný, I; Havlíková, H; Hill, M; Kancheva, L; Kancheva, R; Popov, P; Pouzar, V; Stárka, L; Vrbíková, J1
Gruol, DL; Sabeti, J1
Chiao, YB; Gavaler, JS; Johnston, DE; Van Thiel, DH1
Devaud, LL; Morrow, AL; Paul, SM; Purdy, RH1

Reviews

2 review(s) available for pregnenolone and Alcoholism

ArticleYear
Stress and drug abuse-related disorders: The promising therapeutic value of neurosteroids focus on pregnenolone-progesterone-allopregnanolone pathway.
    Frontiers in neuroendocrinology, 2019, Volume: 55

    Topics: Alcoholism; Animals; Marijuana Use; Neurosteroids; Pregnanolone; Pregnenolone; Progesterone; Signal Transduction; Stress, Psychological

2019
Neuroactive steroid modulators of the stress response.
    Annals of the New York Academy of Sciences, 1995, Dec-29, Volume: 771

    Topics: Adrenalectomy; Alcoholism; Animals; Bridged Bicyclo Compounds, Heterocyclic; Desoxycorticosterone; Estrus; Female; Flunitrazepam; Hypothalamo-Hypophyseal System; Male; Menstruation; Pregnancy; Pregnanolone; Pregnenolone; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Stress, Physiological

1995

Trials

1 trial(s) available for pregnenolone and Alcoholism

ArticleYear
Pregnenolone effects on provoked alcohol craving, anxiety, HPA axis, and autonomic arousal in individuals with alcohol use disorder.
    Psychopharmacology, 2023, Volume: 240, Issue:1

    Topics: Alcohol Drinking; Alcoholism; Anxiety; Arousal; Craving; Cues; Ethanol; Humans; Hypothalamo-Hypophyseal System; Neurosteroids; Pituitary-Adrenal System; Pregnenolone; Recurrence

2023

Other Studies

7 other study(ies) available for pregnenolone and Alcoholism

ArticleYear
Assessment of pregnenolone effects on alcohol intake and preference in male alcohol preferring (P) rats.
    European journal of pharmacology, 2014, Oct-05, Volume: 740

    Topics: Alcohol Drinking; Alcoholism; Animals; Male; Pregnenolone; Rats; Rats, Wistar; Self Administration

2014
Increased steroid hormone dehydroepiandrosterone and pregnenolone levels in post-mortem brain samples of alcoholics.
    Alcohol (Fayetteville, N.Y.), 2016, Volume: 52

    Topics: Adolescent; Adult; Aged; Alcoholism; Brain; Dehydroepiandrosterone; Female; Humans; Male; Middle Aged; Pregnenolone; Young Adult

2016
Pregnenolone and ganaxolone reduce operant ethanol self-administration in alcohol-preferring p rats.
    Alcoholism, clinical and experimental research, 2010, Volume: 34, Issue:12

    Topics: Alcoholism; Animals; Cerebral Cortex; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ethanol; Male; Motor Activity; Pregnanolone; Pregnenolone; Rats; Rats, Inbred Strains; Self Administration

2010
Pregnenolone sulfate, dehydroepiandrosterone sulfate and allotetrahydrodeoxycorticosterone affect rapid tolerance to the hypothermic effect of ethanol.
    Brain research bulletin, 2002, Volume: 58, Issue:1

    Topics: Alcoholism; Animals; Body Temperature; Central Nervous System Depressants; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Drug Interactions; Drug Tolerance; Ethanol; Hypothermia; Male; Mice; Pregnenolone

2002
Altered profiles of serum neuroactive steroids in premenopausal women treated for alcohol addiction.
    Steroids, 2005, Volume: 70, Issue:8

    Topics: Alcoholism; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydrocortisone; Pregnanolone; Pregnenolone; Premenopause; Progesterone; Radioimmunoassay; Stereoisomerism; Steroids; Time Factors

2005
Emergence of NMDAR-independent long-term potentiation at hippocampal CA1 synapses following early adolescent exposure to chronic intermittent ethanol: role for sigma-receptors.
    Hippocampus, 2008, Volume: 18, Issue:2

    Topics: Age Factors; Alcoholism; Animals; Central Nervous System Depressants; Dendrites; Electrophysiology; Ethanol; Hippocampus; Long-Term Potentiation; Male; Neuronal Plasticity; Pregnenolone; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Synapses; Synaptic Transmission

2008
Effect of chronic ethanol feeding on testicular content of enzymes required for testosteronogenesis.
    Alcoholism, clinical and experimental research, 1981,Spring, Volume: 5, Issue:2

    Topics: 17-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Alcoholism; Aldehyde-Lyases; Animals; Diet; Humans; Hydroxyprogesterones; Luteinizing Hormone; Male; Pregnenolone; Rats; Steroid 17-alpha-Hydroxylase; Testis; Testosterone

1981