pregnenolone has been researched along with Adrenal Cancer in 69 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 63 (91.30) | 18.7374 |
| 1990's | 4 (5.80) | 18.2507 |
| 2000's | 1 (1.45) | 29.6817 |
| 2010's | 1 (1.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Malevanaya, EV; Shafigullina, ZR; Velikanova, LI; Vorokhobina, NV | 1 |
| BAULIEU, EE; LEBEAU, MC | 1 |
| KORENMAN, SG; LIPSETT, MB | 1 |
| BUONASSISI, V; SATO, G; STOLLAR, V | 1 |
| BRYSON, MJ; SWEAT, ML | 1 |
| DORFMAN, RI; GABRILOVE, JL; RAHEJA, MC; SHARMA, DC | 1 |
| LIEBERMAN, S; ROBERTS, KD; VANDE WIELE, RL | 1 |
| Betz, G; Hall, PF; Osawa, S | 1 |
| Mathur, RS; Williamson, HO; Wohltmann, H | 1 |
| Freeman, DA; Gocze, PM | 1 |
| DeWitte, F; Gizard, F; Hum, DW; Lavallee, B; Staels, B; Teissier, E | 1 |
| Cameron, EH; Collins, W | 1 |
| Deshpande, N | 1 |
| Abraham, GE; Chakmakjian, ZH | 1 |
| Auersperg, N; Chen, LM | 1 |
| Hasegawa, K; Igarashi, T; Itoh, Y; Kawakami, F; Moriwaki, K; Nishikawa, M; Sugase, T | 1 |
| Liddle, GW; McKenna, TJ; Miller, RB | 1 |
| Hall, PF; Mrotek, JJ | 1 |
| Hall, PF; Nakamura, M; Watanuki, M | 1 |
| Kumagai, A; Mikami, K; Nishikawa, T; Tamura, Y; Yamamoto, M | 1 |
| Charpponnier, C; Gabbiani, G; Hall, PF; Nakamura, M | 1 |
| Adessi, G; Jayle, MF; Nhuan, TQ; Sebaoun, J | 1 |
| Afinogenova, SA; Iudaev, NA | 1 |
| Knipling, L; Sackett, DL; Shiver, TM; Wolff, J | 1 |
| Berkovich, A; Costa, E; Guidotti, A; Krueger, KE; Papadopoulos, V | 1 |
| Itakura, M; Koide, Y; Kuzuya, N; Matsumara, M; Murayama, Y; Nakamura, S; Okuda, Y; Takuwa, Y; Tomizawa, H; Watanabe, Y | 1 |
| Brown, JW; Carballeira, A; Fishman, LM; Trujillo, D | 1 |
| Sackett, DL; Wolff, J | 1 |
| Betz, G; Hall, PF | 1 |
| Contreras, P; Ravanal, M; Serón-Ferré, M | 1 |
| Osawa, N | 1 |
| Andersen, RN; Givens, JR; Pittaway, DE | 1 |
| Anderson, JM; McCormick, MH; Neville, AM; Webb, JL | 1 |
| Axelrod, LR; Goldzieher, JW; Lecocq, FR | 1 |
| Tamaoki, BI | 1 |
| Anderson, AB; Cameron, EH; Griffiths, K; Jones, D; Jones, T | 1 |
| Emerson, K; Rose, LI; Villee, DB; Williams, GH | 1 |
| Daly, JR; Gower, DB; Snodgrass, GJ; Stern, MI | 1 |
| Cameron, EH; Griffiths, K; Hammerstein, J; Jones, D; Morris, S | 1 |
| Cameron, EH; Maynard, PV | 2 |
| Hamilton, W; Taylor, T | 1 |
| Jungmann, RA; Nishida, S | 1 |
| Calvin, HI; Lieberman, S | 1 |
| Pierson, RW | 1 |
| August, G; David, R; Gandy, HM | 1 |
| Fiedler, R; Kowal, J | 1 |
| Dominguez, OV; Huseby, RA | 1 |
| Kowal, J | 3 |
| Schimmer, BP | 1 |
| Hashimoto, K; Sharma, RK | 1 |
| Sharma, RK | 1 |
| Temple, R; Wolff, J | 1 |
| Jungmann, RA; Nishida, S; Schweppe, JS | 1 |
| Brush, JS; Sharma, RK; Sutliff, LS | 1 |
| Nishida, S | 1 |
| Carballeira, A; Cheng, SC; Fishman, LM | 1 |
| Brush, JS; Sharma, RK | 1 |
| Bryson, MJ; Reynolds, WA; Sweat, ML; Young, RB | 1 |
| Cameron, EH; Griffiths, K | 1 |
| Cohen, RB; Kliman, B; Neeman, J; Weinstein, RL | 1 |
| Axelrod, LR; Goldzieher, JW; Woodhead, DM | 1 |
| Cameron, EH; Cunningham, D; Griffiths, K | 1 |
| Riley, WJ | 1 |
| Dufau, ML; Kliman, B; Villee, DB | 1 |
| Cara, J | 1 |
| Dorfman, RI; Gabrilove, JL; Raman, PB; Sharma, DC | 1 |
2 review(s) available for pregnenolone and Adrenal Cancer
| Article | Year |
|---|---|
ANDROGEN METABOLISM.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Androsterone; Blood; Chorionic Gonadotropin; Cushing Syndrome; Dysgerminoma; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Gonadotropins; Humans; Hypertrichosis; Hypogonadism; Metabolism; Ovarian Neoplasms; Ovary; Polycystic Ovary Syndrome; Pregnenolone; Progesterone; Testosterone; Urine; Virilism | 1964 |
[Adrenocorticotrophic hormone (ACTH)].
Topics: Adenylyl Cyclases; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Animals; Chloramphenicol; Cholesterol; Chromatography, DEAE-Cellulose; Cyclic AMP; Cycloheximide; Dactinomycin; Mitochondria; Pregnenolone; Puromycin; Rats | 1971 |
67 other study(ies) available for pregnenolone and Adrenal Cancer
| Article | Year |
|---|---|
Gas Chromatography-Mass Spectrometry Analysis of Urinary Steroid Metabolomics for Detection of Early Signs of Adrenal Neoplasm Malignancy in Patients with Cushing's Syndrome.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adrenal Gland Neoplasms; Adrenocortical Adenoma; Adult; Androstenediols; Biomarkers, Tumor; Cortodoxone; Cushing Syndrome; Early Detection of Cancer; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Metabolomics; Middle Aged; Neoplasm Grading; Oxidoreductases; Pregnenediones; Pregnenes; Pregnenolone | 2019 |
IN VITRO BIOSYNTHESIS OF CORTICOSTEROID SULFATES BY ADRENAL TUMORAL TISSUE.
Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Carbon Isotopes; Chromatography; Corticosterone; Cortisone; Dehydroepiandrosterone; Desoxycorticosterone; Hydrocortisone; In Vitro Techniques; Metabolism; Pathology; Pregnenolone; Sulfates; Urine | 1963 |
STUDIES ON HORMONE SECRETING ADRENOCORTICAL TUMOR IN TISSUE CULTURE.
Topics: Adenine Nucleotides; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Ascorbic Acid; Histocytochemistry; Metabolism; NADP; Neoplasms, Experimental; Oxidoreductases; Pharmacology; Pregnenolone; Research; Tissue Culture Techniques | 1964 |
LOSS OF TWO STEROID 11 BETA-HYDROXYLATING COMPONENTS IN A RAT ADRENOCORTICAL CARCINOMA.
Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocortical Carcinoma; Desoxycorticosterone; Metabolism; Neoplasms; Neoplasms, Experimental; Pregnenolone; Progesterone; Rats; Research | 1964 |
STUDIES ON A FEMINIZING HUMAN ADRENAL TUMOR. I. BIOSYNTHESIS IN VITRO OF STEROID HORMONES FROM PREGNENOLONE-4-14C AND PROGESTERONE-4-14C.
Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Carbon Isotopes; Chromatography; Desoxycorticosterone; Estradiol; Estrogens; Estrone; Humans; Hydroxyprogesterones; In Vitro Techniques; Metabolism; Neoplasms; Pregnenolone; Progesterone; Radiometry; Research; Steroids; Testosterone | 1965 |
17alpha-Hydroxypregnenolone as a precursor of urinary steroids in a patient with a virilizing adenoma of the adrenal.
Topics: 17-alpha-Hydroxypregnenolone; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Female; Humans; Pregnenolone; Steroids; Virilism | 1961 |
Role of actin in the responses of adrenal cells to ACTH and cyclic AMP: inhibition by DNase I.
Topics: Actins; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Algestone; Algestone Acetophenide; Animals; Bucladesine; Cell Fusion; Cell Line; Cholesterol; Cyclic AMP; Deoxyribonucleases; Erythrocyte Membrane; Intracellular Membranes; Iodine Radioisotopes; Kinetics; Mice; Mitochondria; Pregnenolone; Rabbits | 1984 |
Sexual precocity in a female infant due to feminizing adrenal carcinoma.
Topics: Adrenal Gland Neoplasms; Dehydroepiandrosterone; Female; Follow-Up Studies; Humans; Infant; Karyotyping; Pregnenolone; Puberty, Precocious | 1980 |
Plasma membrane cholesterol is utilized as steroidogenic substrate in Y-1 mouse adrenal tumor cells and normal sheep adrenal cells.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Algestone; Animals; Bucladesine; Cell Membrane; Cells, Cultured; Cholesterol; Mice; Pregnenolone; Sheep; Sterol O-Acyltransferase; Time Factors; Tumor Cells, Cultured | 1993 |
The transcriptional regulating protein of 132 kDa (TReP-132) enhances P450scc gene transcription through interaction with steroidogenic factor-1 in human adrenal cells.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Amino Acid Motifs; Animals; Blotting, Western; Cholesterol Side-Chain Cleavage Enzyme; Chromatography, High Pressure Liquid; DNA-Binding Proteins; DNA, Complementary; E1A-Associated p300 Protein; Fushi Tarazu Transcription Factors; Glutathione Transferase; Homeodomain Proteins; Humans; Luciferases; Mice; Models, Genetic; Nuclear Proteins; Plasmids; Precipitin Tests; Pregnenolone; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Receptors, Cytoplasmic and Nuclear; Steroidogenic Factor 1; Time Factors; Trans-Activators; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 2002 |
Proceedings: Steroid metabolism by normal and tumour-bearing adrenals of BALB/c mice.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Androstenediols; Animals; Castration; Dehydroepiandrosterone; Female; Gonadal Steroid Hormones; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Pregnenolone; Testosterone | 1975 |
Hormonal imbalance in breast cancer.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Androgens; Androstenedione; Breast Neoplasms; Cholesterol; Dehydroepiandrosterone; Female; Humans; Hydroxysteroid Dehydrogenases; Lyases; Neoplasm Metastasis; Pregnenolone; Progesterone; Steroid Isomerases | 1975 |
Peripheral steroid levels in a patient with virilizing adrenal adenoma.
Topics: 17-alpha-Hydroxypregnenolone; Adenoma; Adrenal Gland Neoplasms; Adult; Androstenedione; Dehydroepiandrosterone; Dexamethasone; Dihydrotestosterone; Estradiol; Estrone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Progesterone; Steroids; Testosterone; Virilism | 1975 |
Response to ACTH and dibutyryl cyclic AMP by enucleated adrenocortical tumor cells.
Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Bucladesine; Cell Line; Culture Media; Cytochalasin B; Cytoplasm; Leucine; Neoplasms, Experimental; Pregnenolone; Protein Biosynthesis; Steroids; Time Factors | 1976 |
[Studies on the responsiveness of human adrenocortical tumors to ACTH the clinical and experimental observations (author's transl)].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Animals; Carcinoma; Cyclic AMP; Cycloheximide; Female; Humans; In Vitro Techniques; Male; Middle Aged; Mitochondria; Pregnenolone; Progesterone; Rats | 1975 |
Plasma pregnenolone and 17-OH-pregnenolone in patients with adrenal tumors, ACTH excess, or idiopathic hirsutism.
Topics: 17-alpha-Hydroxypregnenolone; Adenocarcinoma; Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Carcinoma, Bronchogenic; Circadian Rhythm; Cushing Syndrome; Dexamethasone; Female; Hirsutism; Humans; Hydrocortisone; Lung Neoplasms; Male; Menopause; Ovary; Pregnenolone; Thymoma; Thymus Neoplasms | 1977 |
Response of adrenal tumor cells to adrenocorticotropin: site of inhibition by cytochalasin B.
Topics: 20-alpha-Dihydroprogesterone; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Biological Transport; Bucladesine; Cholesterol; Cytochalasin B; Cytochrome P-450 Enzyme System; Drug Interactions; Mice; Mitochondria; Pregnenolone; Progesterone; Protein Biosynthesis | 1977 |
On the role of protein synthesis in the response of adrenal tumor cells to ACTH.
Topics: Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aminoglutethimide; Bucladesine; Cell Line; Chloramphenicol; Cholesterol; Cycloheximide; Dactinomycin; Mitochondria; Pregnenolone; Protein Biosynthesis; Puromycin | 1978 |
Comparative study of cyclic AMP-generation system, steroid biosynthesis and lipid metabolism in vitro in ACTH responsive and unresponsive adrenal tumors.
Topics: Adenoma; Adenylyl Cyclases; Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Angiotensin II; Cholesterol; Cyclic AMP; Female; Humans; In Vitro Techniques; Lipid Metabolism; Male; Middle Aged; Neoplasms, Hormone-Dependent; Phosphoric Diester Hydrolases; Pregnenolone | 1979 |
The role of microfilaments in the response of adrenal tumor cells to adrenocorticotropic hormone.
Topics: Actins; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Algestone; Animals; Bucladesine; Cholesterol; Immunoglobulin G; Intracellular Membranes; Kinetics; Liposomes; Mitochondria; Pregnenolone; Steroids | 1979 |
[Biosynthetis in vitro of estrogens by an adrenal cortex tumor].
Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Chromatography, Gas; Chromatography, Thin Layer; Culture Techniques; Estradiol; Estriol; Estrogens; Estrone; Female; Humans; Hydroxysteroid Dehydrogenases; Methyltransferases; Middle Aged; Mixed Function Oxygenases; Pregnenolone; Progesterone | 1975 |
[Pathways of corticosteroid biosynthesis in human adrenals (Itsenko-Cushing disease)].
Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Cholesterol; Cushing Syndrome; Humans; Hyperplasia; Kinetics; Mitochondria; Pregnenolone; Progesterone | 1976 |
Intermediate filaments and steroidogenesis in adrenal Y-1 cells: acrylamide stimulation of steroid production.
Topics: Acrylamide; Acrylamides; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Cell Division; Colchicine; Cyclic AMP; DNA; Intermediate Filaments; Mice; Microtubules; Pregnenolone; Steroids; Tumor Cells, Cultured | 1992 |
Diazepam binding inhibitor and its processing products stimulate mitochondrial steroid biosynthesis via an interaction with mitochondrial benzodiazepine receptors.
Topics: Adrenal Cortex; Adrenal Gland Neoplasms; Amino Acid Sequence; Animals; Brain; Cell Line; Chromatography, High Pressure Liquid; Diazepam Binding Inhibitor; Kinetics; Leydig Cell Tumor; Mice; Mitochondria; Molecular Sequence Data; Neuropeptides; Peptide Fragments; Peptides; Pregnenolone; Rats; Receptors, GABA-A; Steroids | 1991 |
Successful treatment of a metastatic hormone-producing adrenal cancer by a combination of mitotane, tegafur and surgical resection.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Gland Neoplasms; Adult; Aldosterone; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Corticosterone; Heart Neoplasms; Humans; Hydrocortisone; Liver Neoplasms; Lung Neoplasms; Male; Mitotane; Pregnenolone; Tegafur; Testosterone | 1990 |
Content and biosynthesis of cortisol in aldosterone-producing adenomas.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Cholesterol; Female; Humans; Hydrocortisone; Kinetics; Male; Microsomes; Middle Aged; Mitochondria; Pregnenolone | 1989 |
Cyclic AMP-independent stimulation of steroidogenesis in Y-1 adrenal tumor cells by antimitotic agents.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Alkaloids; Animals; Cell Line; Cholera Toxin; Colchicine; Cyclic AMP; Demecolcine; Mice; Microtubules; Paclitaxel; Pregnenolone; Protein Kinases; Steroids; Vinblastine | 1986 |
Steroidogenesis in adrenal tumor cells: influence of cell shape.
Topics: 20-alpha-Dihydroprogesterone; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Biological Transport; Bucladesine; Cell Adhesion; Cell Line; Cholesterol; Cyclic AMP; DNA; Intracellular Membranes; Membrane Lipids; Mitochondria; Polyhydroxyethyl Methacrylate; Polylysine; Pregnenolone; Progesterone | 1987 |
[Separation and characterization by high pressure liquid chromatography of delta(4)-3-ketosteroids synthetized from 3H-pregnenolone by an ectopic adrenal tumor treated with ketoconazole].
Topics: Adrenal Gland Neoplasms; Chromatography, High Pressure Liquid; Female; Humans; In Vitro Techniques; Ketoconazole; Ketosteroids; Pregnenolone | 1987 |
In vitro on an HCG responsive, testosterone secreting adrenal cortical adenoma.
Topics: Acetates; Adenoma; Adenosine Triphosphate; Adrenal Gland Neoplasms; Androstenedione; Carbon Radioisotopes; Chorionic Gonadotropin; Coenzymes; Dehydroepiandrosterone; Estrone; Female; Humans; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Mitochondria; NAD; NADP; Pregnenolone; Progesterone; Radioimmunoassay; Subcellular Fractions; Testosterone; Tritium | 1973 |
Steroid biosynthesis in vitro and in tissue culture by adrenal tumours of mice of the CE strain.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; Adrenal Gland Neoplasms; Animals; Autoradiography; Carbon Isotopes; Chromatography, Paper; Culture Techniques; Dehydroepiandrosterone; Desoxycorticosterone; Female; Histocytochemistry; Hydrocortisone; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Mice; Pregnenolone; Rodent Diseases; Steroids; Tritium | 1968 |
Biosynthesis of allo-3-beta-tetrahydrocortisol (Reichstein's substance V) by an adrenal adenoma.
Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Androstanes; Carbon Isotopes; Chemistry, Clinical; Corticosterone; Crystallization; Dehydroepiandrosterone; Female; Hirsutism; Humans; Hydrocortisone; Pregnenolone | 1969 |
A comparative study of steroid biosyntheses in vitro. In clear cell adenoma and its adjacent tissue of human adrenal gland.
Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Carbon Isotopes; Chromatography, Thin Layer; Corticosterone; Cushing Syndrome; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Pregnenolone; Progesterone; Steroids; Testosterone | 1969 |
Further studies on the relationship between C19- and C21-steroid synthesis in the human adrenal gland.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adenoma; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Androgens; Breast Neoplasms; Carbon Isotopes; Dehydroepiandrosterone; Estrogens; Female; Humans; Hydrocortisone; In Vitro Techniques; Pregnenolone; Testosterone; Transferases; Tritium | 1969 |
Steroidal and gonadotropin evaluation of a patient with a feminizing tumor of the adrenal gland. In vivo and in vitro studies.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenalectomy; Chromatography; Dehydroepiandrosterone; Desoxycorticosterone; Dexamethasone; Estradiol; Estriol; Estrogens; Feminization; Follicle Stimulating Hormone; Gonadotropins; Humans; Hydrocortisone; In Vitro Techniques; Luteinizing Hormone; Male; Metabolism, Inborn Errors; Middle Aged; Mixed Function Oxygenases; Nephrectomy; Prednisone; Pregnenolone; Radioimmunoassay; Sex Characteristics; Tritium | 1969 |
Steroid excretion and biosynthesis with special reference to C19-delta16-steroids in an infant with a virilizing adrenocortical carcinoma.
Topics: Adrenal Gland Neoplasms; Androstanes; Androsterone; Carbon Isotopes; Carcinoma; Chromatography, Gas; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Infant; Pregnenolone; Progesterone | 1970 |
Steroid synthesis in a human virilising adrenal carcinoma - some unusual features.
Topics: Adrenal Gland Neoplasms; Adult; Androstanes; Carbon Isotopes; Chromatography, Thin Layer; Dehydroepiandrosterone; Female; Hirsutism; Humans; In Vitro Techniques; Pregnenolone; Progesterone; Radioisotope Dilution Technique; Tritium; Virilism | 1970 |
Metabolism of C 19 steroids by homogenates of normal rat and mouse adrenal tissue, and of the Snell transplantable rat adrenocortical tumour 494.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Androstanes; Androsterone; Animals; Carbon Isotopes; Cholesterol; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; In Vitro Techniques; Neoplasms, Experimental; Pregnenolone; Rats; Tritium | 1972 |
Metabolism of C 19 -steroids by homogenates of normal rat and mouse adrenal tissue and of the Snell transplantable rat adrenocortical tumour 494.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Androstanes; Androsterone; Animals; Carbon Isotopes; Cholesterol; Dehydroepiandrosterone; Etiocholanolone; In Vitro Techniques; Ketones; Mice; Neoplasms, Experimental; Pregnenolone; Rats; Steroids; Tritium | 1972 |
Human foetal adrenal 4-ene-3-oxosteroid synthesis: an investigation of (4- 14 C) pregnenolone and (4- 14 C)-dehydroepiandrosterone metabolism using new techniques.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Androstenes; Carbon Isotopes; Chromatography, Thin Layer; Cortisone; Dehydroepiandrosterone; Fetus; Gestational Age; Humans; Hydrocortisone; In Vitro Techniques; Methods; Pregnenolone; Progesterone; Testosterone; Tritium | 1973 |
Biosynthesis of steroids from (14C)cholesterol, (3H) progesterone and (3H)pregnenolone by human adrenal carcinoma tissue.
Topics: Adrenal Gland Neoplasms; Androstenedione; Carbon Radioisotopes; Carcinoma; Cholesterol; Chromatography, Paper; Chromatography, Thin Layer; Crystallization; Dehydroepiandrosterone; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Isotope Labeling; Middle Aged; Pregnenolone; Progesterone; Steroids; Tritium; Virilism | 1974 |
Studies on the metabolism of pregnenolone sulfate.
Topics: Adenoma; Adrenal Gland Neoplasms; Androsterone; Chromatography, Paper; Hormones; Humans; In Vitro Techniques; Pregnanediol; Pregnenolone; Spectrophotometry; Steroids; Sulfur Isotopes; Tritium; Urine | 1966 |
Metabolism of steroid hormones in adrenal cortex tumor cultures.
Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Chromatography, Thin Layer; Culture Techniques; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Infrared Rays; Kinetics; Mice; Neoplasms, Experimental; Pregnenolone; Spectrophotometry; Steroids; Tritium | 1967 |
A virilizing adrenal tumor with borderline elevation of urinary 17-ketosteroids.
Topics: 17-Ketosteroids; Adenoma; Adrenal Gland Neoplasms; Androgens; Androsterone; Child; Dehydroepiandrosterone; Humans; Hydroxysteroid Dehydrogenases; Male; Pregnenolone; Steroids; Testosterone | 1968 |
Arenal cells in tissue culture. I. Assay of steroid products; steroidogenic responses to peptide hormones.
Topics: Acetates; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Androstanes; Animals; Carbon Isotopes; Cholesterol; Chromatography, Thin Layer; Clone Cells; Culture Techniques; Fluorometry; Kinetics; Male; Methods; Mice; Peptides; Pregnenolone; Progesterone; Progestins; Spectrophotometry; Stimulation, Chemical; Tritium | 1968 |
In vivo and in vitro studies of steroid production by a luteoma and an adrenal cortical carcinoma in mice.
Topics: 17-Hydroxycorticosteroids; Adrenal Gland Neoplasms; Adrenal Insufficiency; Adrenalectomy; Androstanes; Animals; Atrophy; Carbon Isotopes; Carcinoma; Castration; Chromatography; Desoxycorticosterone; Female; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Ovarian Neoplasms; Ovary; Pregnenolone; Progesterone; Testosterone; Thecoma; Tritium | 1969 |
Adrenal cells in tissue culture. IV. Use of an inhibitor of steroid synthesis for the study of ACTH action.
Topics: Acetates; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aminoglutethimide; Aniline Compounds; Animals; Anticonvulsants; Carbon Isotopes; Cell-Free System; Cholesterol; Culture Techniques; Depression, Chemical; Feedback; Glucose; Glycolysis; Hydroxysteroid Dehydrogenases; Mice; Mixed Function Oxygenases; Pregnenolone; Pyridones; Rats; Stimulation, Chemical; Tritium | 1969 |
Phenotypically variant adrenal tumor cell cultures with biochemical lesions in the ACTH-stimulated steroidogenic pathway.
Topics: Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Animals; Antigens; Cell Line; Chromatography, Thin Layer; Clone Cells; Complement Fixation Tests; Culture Techniques; Cyclic AMP; Karyotyping; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Pregnanediol; Pregnenolone; Steroids | 1969 |
Adrenal cells in tissue culture. VII. The effect of inhibitors of protein synthesis on steroidogenesis and glycolysis.
Topics: Acetates; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Animals; Carbon Isotopes; Cell-Free System; Cholesterol; Culture Techniques; Cycloheximide; Dactinomycin; Depression, Chemical; Glycolysis; Leucine; Lysine; Mice; Neoplasm Proteins; Neoplasms, Experimental; Pregnenolone; Puromycin; RNA, Neoplasm; Tritium; Uridine | 1970 |
Ultrastructural studies and metabolic regulation of isolated adrenocortical carcinoma cells of rat.
Topics: Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Animals; Carcinoma; Chromatography, Thin Layer; Corticosterone; Cortisone; Cyclic AMP; Cyclic GMP; Depression, Chemical; In Vitro Techniques; Microscopy, Electron; Neoplasms, Experimental; Pregnenolone; Progesterone; Rats; Tritium | 1972 |
Metabolic regulation of steroidogenesis in adrenocortical carcinoma cells of rat. Effect of adrenocorticotropin and adenosine cyclic 3':5'-monophosphate on corticosteroidogenesis.
Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Butyrates; Carbon Isotopes; Carcinoma; Corticosterone; Cyclic AMP; Desoxycorticosterone; In Vitro Techniques; Male; Pregnenolone; Progesterone; Rats; Tritium | 1973 |
Stimulation of steroid secretion by antimicrotubular agents.
Topics: Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Cell Line; Chromatography, Thin Layer; Colchicine; Cyclic AMP; Deuterium; Hydroxysteroids; Ketosteroids; Leydig Cell Tumor; Mice; Microtubules; Mitosis; Podophyllotoxin; Pregnenes; Pregnenolone; Protein Biosynthesis; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Stimulation, Chemical; Time Factors; Vinblastine | 1973 |
Biosynthesis of steroids from cholesterol-14C by human adrenal carcinoma tissue.
Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Androstenedione; Bucladesine; Carbon Radioisotopes; Carcinoma; Cholesterol; Chromatography; Dehydroepiandrosterone; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Middle Aged; Phenols; Pregnenolone; Progesterone; Testosterone; Tritium | 1973 |
Metabolic regulation and adenyl cyclase activity of adrenocortical carcinoma cultured cells.
Topics: Adenylyl Cyclases; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Animals; Cell Fractionation; Cell Membrane; Cell Nucleus; Cells, Cultured; Cholesterol; Corticosterone; Cyclic AMP; Desoxycorticosterone; Epinephrine; Mitochondria; Neoplasms, Experimental; Pregnenolone; Rats | 1974 |
[Biosynthesis of steroids by human adrenal cancer tissue--effects of ACTH and cyclic AMP].
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Androstenedione; Carbon Radioisotopes; Cholesterol; Chromatography, Paper; Cyclic AMP; Dehydroepiandrosterone; Female; Glucocorticoids; Humans; Hydroxyprogesterones; In Vitro Techniques; Middle Aged; Pregnenolone; Progesterone; Tritium | 1974 |
Adrenal cells in tissue culture. 3. Effect of adrenocorticotropin and 3',5'-cyclic adenosine monophosphate on 11 beta-hydroxylase and other steroidogenic enzymes.
Topics: Adenine Nucleotides; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Animals; Calcium; Carbon Isotopes; Citrates; Clone Cells; Culture Techniques; Cyclic AMP; Hydroxysteroid Dehydrogenases; Mice; Mitochondria; Mixed Function Oxygenases; NADP; Neoplasms, Experimental; Pregnanes; Pregnenolone; Progesterone; Steroids; Sterols; Stimulation, Chemical; Time Factors; Tritium | 1969 |
Metabolism of (4-14C) cholesterol by human adrenal glands in vitro and its inhibition by metyrapone.
Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocortical Hyperfunction; Adult; Androstenedione; Carbon Radioisotopes; Cholesterol; Chromatography, Paper; Chromatography, Thin Layer; Corticosterone; Depression, Chemical; Desoxycorticosterone; Female; Humans; Hydrocortisone; In Vitro Techniques; Metyrapone; Middle Aged; Pregnenolone; Progesterone; Tritium | 1974 |
Metabolic regulation of steroid steroidogenesis in isolated adrenal and adrenocortical carcinoma cells of rat. The incorporation of (20S)-20-(7- 3 H)hydroxycholesterol into deoxycorticosterone and corticosterone.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Animals; Carbon Isotopes; Carcinoma; Cholesterol; Chromatography, Thin Layer; Corticosterone; Desoxycorticosterone; Pregnenolone; Rats; Tritium | 1973 |
Biosynthesis of steroid hormones in a human feminizing adrenal carcinoma.
Topics: 17-Ketosteroids; Adrenal Gland Neoplasms; Carbon Isotopes; Chromatography, Paper; Estradiol; Estrone; Humans; In Vitro Techniques; Male; Middle Aged; Pregnenolone; Progesterone; Radioisotope Dilution Technique; Testosterone; Tissue Extracts | 1968 |
Corticosteroid synthesis in a clear cell adenoma: a time-based study.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Carbon Isotopes; Chromatography, Thin Layer; Cushing Syndrome; Female; Humans; Hydrocortisone; In Vitro Techniques; Pregnenolone; Progesterone; Radioisotope Dilution Technique; Time Factors; Tritium | 1968 |
Deficient 17-hydroxylation in a corticosterone producing adrenal tumor from an infant with hemihypertrophy and visceromegaly.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Abnormalities, Multiple; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Corticosterone; Desoxycorticosterone; Female; Growth Hormone; Humans; Hydrocortisone; Hydroxyprogesterones; Hyperplasia; Hypoglycemia; Infant; Islets of Langerhans; Kidney Diseases; Metabolism, Inborn Errors; Mixed Function Oxygenases; Pregnanediol; Pregnanetriol; Pregnenolone; Vanilmandelic Acid | 1970 |
Steroid biosynthesis in a feminizing adrenal carcinoma.
Topics: 17-Hydroxycorticosteroids; Adrenal Gland Neoplasms; Adult; Aldosterone; Androstanes; Biotransformation; Carbon Isotopes; Carcinoma; Chromatography; Corticosterone; Desoxycorticosterone; Estrone; Feminization; Humans; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Male; Pregnenolone; Progesterone; Sex Characteristics; Steroids; Testosterone; Tritium | 1969 |
A comparison of the conversion in vitro of pregnenolone sulphate and pregnenolone to steroid hormones by tissue from a clear cell adenoma of the adrenal gland.
Topics: 17-alpha-Hydroxypregnenolone; Adenoma; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adult; Androgens; Carbon Isotopes; Chromatography, Thin Layer; Corticosterone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Pregnenolone; Progesterone; Sulfates; Testosterone; Tritium | 1968 |
Urinary excretion of glucuronides and sulfates of acetaldehydogenic steroids.
Topics: Acetaldehyde; Acetates; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Chromatography, Paper; Cushing Syndrome; Glucuronates; Glucuronidase; Humans; Pregnanediol; Pregnanes; Pregnanetriol; Pregnenolone; Sulfates | 1968 |
Pregnenolone metabolism in an aldosterone secreting tumor of the adrenal and its adjacent adrenal tissue.
Topics: 17-alpha-Hydroxypregnenolone; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Androgens; Chemistry, Clinical; Chromatography, Paper; Chromatography, Thin Layer; Crystallization; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Hyperaldosteronism; Mixed Function Oxygenases; Pregnenolone; Tritium | 1968 |
Isolation and identification of 16-OH pregnenolone (pregn-5-en-3 beta,16 alpha-diol-20-one) in urine from a patient with adrenocortical carcinoma.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Neoplasms; Carcinoma; Child; Chromatography; Female; Humans; Pregnanetriol; Pregnenolone; Spectrum Analysis | 1969 |
Biosynthesis of C-18-oxygenated steroids by an aldosterone-secreting human adrenal tumor. Metabolism of [4-14C] progesterone, [1,2-3H]11-deoxycorticosterone, and [4-14C] pregnenolone.
Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Chromatography, Paper; Chromatography, Thin Layer; Desoxycorticosterone; Female; Humans; Hyperaldosteronism; In Vitro Techniques; Pregnenolone; Progesterone; Subcellular Fractions | 1965 |