Page last updated: 2024-08-23

pregnanolone and Spasms, Infantile

pregnanolone has been researched along with Spasms, Infantile in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Aimetti, AA; Amin, S; Bahi-Buisson, N; Benke, TA; Cross, JH; Demarest, ST; Devinsky, O; Fleming, TR; Gasior, M; Knight, EMP; Olson, HE; Specchio, N1
Chern, CJ; Chern, CR; Chodounská, H; Kudová, E; Lauková, M; Schonwald, A; Shakarjian, MP; Velíšek, L; Velíšková, J1
Ko, TS; Lee, M; Velíšek, L; Yum, MS1
Bluestone, DL; Bourgeois, BF; Dodson, WE; Kerrigan, JF; Monaghan, EP; Morton, LD; Nelson, TY; Pellock, JM; Shields, WD1

Trials

2 trial(s) available for pregnanolone and Spasms, Infantile

ArticleYear
Safety and efficacy of ganaxolone in patients with CDKL5 deficiency disorder: results from the double-blind phase of a randomised, placebo-controlled, phase 3 trial.
    The Lancet. Neurology, 2022, Volume: 21, Issue:5

    Topics: Child; Child, Preschool; Double-Blind Method; Epileptic Syndromes; Humans; Infant; Pregnanolone; Prospective Studies; Protein Serine-Threonine Kinases; Seizures; Spasms, Infantile; Treatment Outcome

2022
Ganaxolone for treating intractable infantile spasms: a multicenter, open-label, add-on trial.
    Epilepsy research, 2000, Volume: 42, Issue:2-3

    Topics: Anticonvulsants; Child; Child, Preschool; Female; Humans; Infant; Male; Pilot Projects; Pregnanolone; Spasms, Infantile

2000

Other Studies

2 other study(ies) available for pregnanolone and Spasms, Infantile

ArticleYear
Novel neurosteroid pregnanolone pyroglutamate suppresses neurotoxicity syndrome induced by tetramethylenedisulfotetramine but is ineffective in a rodent model of infantile spasms.
    Pharmacological reports : PR, 2023, Volume: 75, Issue:1

    Topics: Animals; Diazepam; Glutamic Acid; N-Methylaspartate; Neurosteroids; Neurotoxicity Syndromes; Pregnanolone; Pyrrolidonecarboxylic Acid; Rodentia; Spasm; Spasms, Infantile

2023
A potential effect of ganaxolone in an animal model of infantile spasms.
    Epilepsy research, 2014, Volume: 108, Issue:9

    Topics: Age Factors; Anesthetics; Animals; Animals, Newborn; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Excitatory Amino Acid Agonists; Exploratory Behavior; Female; Humans; Infant; Male; N-Methylaspartate; Pregnanolone; Rats; Rats, Sprague-Dawley; Reaction Time; Social Behavior; Spasms, Infantile; Statistics, Nonparametric

2014