Page last updated: 2024-08-23

pregnanolone and Schizophrenia

pregnanolone has been researched along with Schizophrenia in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cai, H; Dougherty, GG; Haas, GL; Keshavan, M; Montrose, DM; Reddy, RD; Yao, JK; Zhou, X1
Allen, TB; Bradford, DW; Brancu, M; Brunca, M; Hamer, RM; Kilts, JD; Marx, CE; Naylor, JC; Shampine, LJ; Strauss, JL; Szabo, ST; Youssef, NA1
Bradford, DW; Buchanan, RW; Dunn, L; Hamer, RM; Keefe, RS; Kilts, JD; Leimone, LA; Lieberman, JA; Marx, CE; Morrow, AL; Naylor, JC; Payne, VM; Porcu, P; Savitz, AJ; Shampine, LJ; Strauss, JL1
Bubenikova-Valesova, V; Chodounska, H; Holubova, K; Rambousek, L; Stuchlik, A; Svoboda, J; Vales, K; Vyklicky, L1
Biggio, G; Fabrazzo, M; Maj, M; Monteleone, P; Pisu, MG; Serra, M; Tortorella, A1

Trials

1 trial(s) available for pregnanolone and Schizophrenia

ArticleYear
Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophrenia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:8

    Topics: Adult; Aged; Brain; Brain Chemistry; Cognition Disorders; Double-Blind Method; Female; Humans; Male; Memory Disorders; Middle Aged; Neuropsychological Tests; Nootropic Agents; Pilot Projects; Placebos; Pregnanolone; Pregnenolone; Schizophrenia; Treatment Outcome; Up-Regulation

2009

Other Studies

4 other study(ies) available for pregnanolone and Schizophrenia

ArticleYear
Pregnenolone-progesterone-allopregnanolone pathway as a potential therapeutic target in first-episode antipsychotic-naïve patients with schizophrenia.
    Psychoneuroendocrinology, 2018, Volume: 90

    Topics: Adult; Antipsychotic Agents; Biomarkers, Pharmacological; Case-Control Studies; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hydrocortisone; Male; Metabolic Networks and Pathways; Pregnanolone; Pregnenolone; Progesterone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome

2018
Exploratory investigation of biomarker candidates for suicide in schizophrenia and bipolar disorder.
    Crisis, 2015, Volume: 36, Issue:1

    Topics: Adult; Aged; Autopsy; Biomarkers; Bipolar Disorder; Brain; Case-Control Studies; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Female; Gas Chromatography-Mass Spectrometry; Gyrus Cinguli; Humans; Male; Middle Aged; Parietal Lobe; Pilot Projects; Pregnanolone; Pregnenolone; Schizophrenia; Suicide; Young Adult

2015
3α5β-Pregnanolone glutamate, a use-dependent NMDA antagonist, reversed spatial learning deficit in an animal model of schizophrenia.
    Behavioural brain research, 2012, Nov-01, Volume: 235, Issue:1

    Topics: Animals; Anxiety; Avoidance Learning; Cognition Disorders; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Male; Motor Activity; Pregnanolone; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Vocalization, Animal

2012
Long-term treatment with clozapine does not affect morning circulating levels of allopregnanolone and THDOC in patients with schizophrenia: a preliminary study.
    Journal of clinical psychopharmacology, 2004, Volume: 24, Issue:4

    Topics: Adult; Analysis of Variance; Circadian Rhythm; Clozapine; Desoxycorticosterone; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pregnanolone; Prospective Studies; Schizophrenia

2004