pregnanolone has been researched along with Pregnancy in 199 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (15.08) | 18.7374 |
| 1990's | 31 (15.58) | 18.2507 |
| 2000's | 53 (26.63) | 29.6817 |
| 2010's | 58 (29.15) | 24.3611 |
| 2020's | 27 (13.57) | 2.80 |
| Authors | Studies |
|---|---|
| Bay, CP; Frye, CA; Peng, L; Pennell, KD; Pennell, PB; Stowe, ZN; Tang, KY; Voinescu, PE | 1 |
| Crombie, GK; Hirst, JJ; Hodgson, DM; Palliser, HK; Shaw, JC; Walker, DW | 2 |
| Betz, JF; Hantsoo, L; Osborne, LM; Payne, JL; Standeven, LR; Voegtline, K; Yenokyan, G | 1 |
| Bixo, M; Dehlin, E; Løvvik, TS; Molin, J; Vanky, E | 1 |
| Battle, CL; Diaz, Z; Howard, MM | 1 |
| Adamičková, A; Gažová, A; Hrubá, O; Massarová, P; Vranecová, K; Žigová, L | 1 |
| Chen, J; Hu, L; Peng, H; Yang, K; Zeng, X; Zhu, W | 1 |
| Ehlert, U; Grötsch, MK; Hettich, T; Wietor, DM | 1 |
| Bakalar, D; Ellegood, J; Hashimoto-Torii, K; Imamura, Y; Lacaille, H; Lerch, JP; O'Reilly, JJ; Penn, AA; Salzbank, J; Sasaki, T; Vacher, CM | 1 |
| Graham, BM; Kershaw, KA; Pestana, JE | 1 |
| Etyemez, S; Miller, KN; Osborne, LM; Özdemir, İ; Payne, JL; Pinna, G; Santovito, LS; Standeven, LR; Voegtline, KM | 1 |
| Graham, BM; Pestana, JE | 1 |
| Leader, LD; O'Connell, M; VandenBerg, A | 1 |
| Barron, RJ; Jarman, AF; MacLean, JV; McGregor, AJ; Wightman, RS | 1 |
| Cieri-Hutcherson, NE; Gosciak, MF; Hutcherson, TC | 1 |
| Bond, JC; Chertavian, E; Cohen, JT; Eldar-Lissai, A; Gerbasi, ME; Hodgkins, P; Johnson, SJ; Meltzer-Brody, S | 1 |
| Kroska, EB; Stowe, ZN | 1 |
| Deligiannidis, KM; Dubuke, ML; Kroll-Desrosiers, AR; Shaffer, SA; Tan, Y | 1 |
| Ghoumari, A; Liere, P; Schumacher, M | 1 |
| Nguyen, DR; Patatanian, E | 1 |
| Payne, JL | 1 |
| Ackerman, MG; Blakemore, JK; Jacobson, MH; Kannan, K; Liu, M; Long, SE; Pinna, G; Romay-Tallon, R; Stein, CR; Trasande, L; Zhu, H | 1 |
| Bäckström, T; Bixo, M; Kangas Flodin, Y; Turkmen, S | 1 |
| Qian, B; Song, J; Wang, C; Zen, Z; Zheng, Z | 1 |
| Cooke, E; Leader, LD; VandenBerg, A; Walkery, A | 1 |
| Christians, U; Dabelea, D; De Bloois, E; Mayne, G | 1 |
| Bakalar, D; Clarkson-Paredes, C; Ellegood, J; Gallo, V; Hashimoto-Torii, K; Imamura, Y; Kratimenos, P; Lacaille, H; Lerch, JP; Liere, P; O'Reilly, JJ; Penn, AA; Popratiloff, A; Salzbank, J; Sasaki, T; Sathyanesan, A; Schumacher, M; Sebaoui, S; Vacher, CM | 1 |
| Bellieni, CV; Petraglia, F; Vannuccini, S | 1 |
| Cumberland, AL; Hirst, JJ; Palliser, HK; Rani, P; Walker, DW | 1 |
| Biggio, F; Boero, G; Concas, A; Congiu, M; Corda, D; Garau, A; Pisu, MG; Porcu, P; Serra, M | 1 |
| Hirst, JJ; Palazzi, K; Palliser, HK; Shaw, JC | 1 |
| Comasco, E; Hellgren, C; Skalkidou, A; Sundström-Poromaa, I | 1 |
| Bäckström, T; Bixo, M; Holmberg, E; Jaukkuri, L; Johansson, M; Löfgren, M; Lundqvist, A; Malinina, E; Ragagnin, G; Sjöstedt, J; Turkmen, S | 1 |
| Bennett, GA; Hirst, JJ; Palazzi, KL; Palliser, HK; Shaw, JC; Walker, DW | 1 |
| Biggio, F; Boero, G; Locci, V; Pisu, MG; Porcu, P; Serra, M | 1 |
| Guintivano, J; Manuck, T; Meltzer-Brody, S | 1 |
| McEvoy, K; Osborne, LM; Payne, JL | 1 |
| Charlet, A; Chavant, V; Gazzo, G; Goumon, Y; Juif, PE; Lacaud, A; Lelièvre, V; Melchior, M; Petit-Demoulière, N; Poisbeau, P | 1 |
| Clemson, C; Colquhoun, H; Deligiannidis, KM; Epperson, CN; Jonas, J; Kanes, S; Li, H; Meltzer-Brody, S; Riesenberg, R; Rubinow, DR; Sankoh, AJ; Schacterle, A | 1 |
| Mody, I | 1 |
| Ansaldi, Y; Genazzani, AR; Pluchino, N | 1 |
| Kalakh, S; Mouihate, A | 1 |
| Deligiannidis, KM; Frederick, B; Kopoyan, A; Kosma, CA; Moore, CM; Rothschild, AJ; Shaffer, SA; Sikoglu, EM; Svenson, AE | 1 |
| Hirst, JJ; Kelleher, MA; Palliser, HK | 1 |
| Hirst, JJ; Kelleher, MA; Palliser, HK; Walker, DW | 2 |
| Casarosa, E; Genazzani, AD; Genazzani, AR; Petignat, P; Pluchino, N; Santoro, A; Wenger, JM | 1 |
| Brunton, PJ; Hirst, JJ; Russell, JA | 1 |
| Bennett, GA; Hirst, JJ; Palliser, HK; Saxby, B; Walker, DW | 1 |
| Burgueño, AL; Cabrerizo, R; Castaño, GO; Fernández Gianotti, T; Flichman, D; Gonzalez Lopez Ledesma, MM; Pirola, CJ; Sookoian, S | 1 |
| Åkerud, H; Bäckström, T; Hellgren, C; Skalkidou, A; Sundström-Poromaa, I | 1 |
| Rubinow, DR; Schiller, CE; Schmidt, PJ | 1 |
| Jenkin, G; Miller, SL; Mortale, M; Sutherland, AE; Walker, DW; Wallace, EM; Yawno, T | 1 |
| Meltzer-Brody, S; Rubinow, DR; Schiller, CE | 1 |
| Brunton, PJ; Donadio, MV; Greenwood, M; Murphy, D; Russell, JA; Seckl, JR; Yao, ST | 1 |
| Cabrera, R; Estrella, CR; García, S; Lara, HE; Yunes, R | 1 |
| Abu-Hayyeh, S; Williamson, C | 1 |
| Langendijk, P; Plush, K; Rault, JL; Yawno, T | 1 |
| Brunton, PJ | 1 |
| Bennett, GA; Cumberland, AL; Hirst, JJ; Kelleher, MA; Palliser, HK; Shaw, JC; Walker, DW | 1 |
| Beckmann, MW; Binder, EB; Braier, A; Brown, T; Clive, M; Cox, O; Fasching, PA; Gispen, F; Goes, F; Guintivano, J; Judy, J; Kaminsky, Z; Kimmel, M; Kornhuber, J; Meilman, S; Osborne, L; Payne, JL | 1 |
| Ball, BA; Berger, T; Conley, AJ; Legacki, EL; Scholtz, EL; Stanley, SD | 1 |
| Crowley, SK; Girdler, SS; Morrow, AL; O'Buckley, TK; Schiller, CE; Stuebe, A | 1 |
| Bennett, GA; Hirst, J; Palliser, HK; Walker, D | 1 |
| Barton, BA; Deligiannidis, KM; Hall, JE; Jaitly, N; Kroll-Desrosiers, AR; Mo, S; Nguyen, HP; Rothschild, AJ; Shaffer, SA; Svenson, A | 1 |
| Genazzani, AR; Pluchino, N; Russo, M | 1 |
| Crombie, GK; Cumberland, AL; Hirst, JJ; Palliser, HK; Walker, DW | 1 |
| Gispen, F; Meilman, S; Osborne, LM; Payne, JL; Sanyal, A; Yenokyan, G | 1 |
| Ciurej, I; Hirst, JJ; Walker, DW; Westcott, KT; Wlodek, ME | 1 |
| Brinton, RD; Wang, JM | 1 |
| Brunton, PJ; Lachowicz, A; McKay, AJ; Ochedalski, T; Piastowska, A; Rebas, E; Russell, JA | 1 |
| Brunelli, SA; Killien, EY; Martinez, AR; Robinson, SA; Skudder, CM; Zimmerberg, B | 1 |
| Castillo-Melendez, M; Hirst, JJ; Walker, DW; Yawno, T | 1 |
| Biggio, G; Concas, A; Cristina Mostallino, M; Follesa, P; Sanna, E | 1 |
| Biggio, G; Concas, A; Follesa, P; Mostallino, MC; Sanna, E | 1 |
| Ferando, I; Maguire, J; Mody, I; Simonsen, C | 1 |
| Frye, CA | 1 |
| Angstmann, T; Gard, G; Giles, W; Harrington, T; Thomson, A; Ward, E | 1 |
| Hirst, JJ; McKendry, AA; Palliser, HK; Walker, DW; Yates, DM | 1 |
| Angioni, MM; Biggio, G; Calza, A; Concas, A; Marra, C; Mostallino, MC; Santoru, F; Sogliano, C | 1 |
| Brunton, PJ; Russell, JA | 1 |
| Andreen, L; Backstrom, T; Johansson, IM; Turkmen, S; Wahlstrom, G | 1 |
| Frye, CA; Paris, JJ | 1 |
| Brunton, PJ; Frye, CA; Hirst, JJ; Russell, JA | 1 |
| Ghosal, R; Kalaivanan, N; Seshagiri, PB; Sukumar, R | 1 |
| Briz, V; Parkash, J; Prevot, V; Sánchez-Redondo, S; Suñol, C | 1 |
| Castillo-Melendez, M; Coleman, HA; Dickinson, H; Fleiss, B; Hirst, JJ; Parkington, HC; Walker, DW; Yawno, T | 1 |
| Bales, J; Brunton, PJ; Russell, JA | 1 |
| Kuver, A; Shen, H; Smith, SS | 1 |
| Abu-Hayyeh, S; Chambers, J; Jamaludin, NA; Lövgren-Sandblom, A; Marschall, HU; Nikolova, V; Oduwole, O; Papacleovoulou, G; Parker, MG; Ravat, S; Rees, M; Selden, C; Tahir, M; Williamson, C | 1 |
| Kabra, M; Kumar, V; Shivaji, S; Umapathy, G | 1 |
| Boustany, RM; Lockhart, EM; Mehrabani, S; Pearlstein, RD; Penning, DH; Warner, DS | 1 |
| Altobelli, D; Cannizzaro, C; Martire, M; Maurizi, S; Preziosi, P | 1 |
| Biggio, G; Eva, C; Oberto, A; Pisu, MG; Serra, M | 1 |
| Molina-Hernandez, M; Olivera Lopez, JI; Perez, JG | 1 |
| Brussaard, AB; Koksma, JJ; Lüddens, H; Rosahl, TW; Smit, AB; van Kesteren, RE; Zwart, R | 1 |
| Billiards, SS; Hirst, JJ; Nguyen, PN; Walker, DW | 1 |
| Bicíková, M; Fait, T; Hampl, R; Havlíková, H; Hill, M; Kancheva, R; Klak, J; Parízek, A; Pouzar, V; Stárka, L; Sulcová, J | 1 |
| Gulinello, M; Smith, S; Sundström Poromaa, I | 1 |
| Beart, PM; Crossley, KJ; Hirst, JJ; Lawrence, AJ; Nitsos, I; Walker, DW | 1 |
| Auchus, RJ; Flück, CE; Miller, WL | 1 |
| CREPY, O; JAYLE, MF; LACHESE, B | 1 |
| Brien, JF; Dringenberg, HC; Iqbal, U; Reynolds, JN | 1 |
| Gizerian, SS; Grobin, AC; Lieberman, JA; Morrow, AL | 1 |
| Hirst, JJ; Nguyen, PN; Ross Young, I; Walker, DW | 1 |
| Frye, CA; Walf, AA | 1 |
| Akwa, Y; Caldeira, JC; Engen, JR; Li, PK; Mameli, M; Purdy, RH; Savage, DD; Valenzuela, CF; Wu, Y | 1 |
| Biggio, F; Biggio, G; Caria, S; Follesa, P; Gorini, G | 1 |
| Cerny, I; Cindr, J; Drbohlav, P; Hájek, Z; Havlíková, H; Hill, M; Kancheva, L; Kancheva, R; Parízek, A; Pasková, A; Pouzar, V; Stárka, L | 1 |
| Davis, C; Davis, M; Hammond, A; Toufexis, DJ | 1 |
| Ball, BG; Brinton, RD; Johnston, PB; Wang, JM | 1 |
| Bäckström, T; Biggio, G; Finn, DA; Janak, PH; Purdy, RH; Valenzuela, CF | 1 |
| Gilbert Evans, SE; Purdy, RH; Romach, MK; Ross, LE; Sellers, EM | 1 |
| Biggio, G; Concas, A; Contu, R; Lello, S; Marotto, MF; Melis, GB; Orrù, MM; Paoletti, AM; Romagnino, S; Zedda, P | 1 |
| Brunelli, SA; Frye, CA; Sumida, K; Zimmerberg, B | 1 |
| de Brito Faturi, C; Leite, JR; Teixeira-Silva, F | 1 |
| Hirst, JJ; Nguyen, P; Walker, DW; Yawno, T | 1 |
| Hirst, JJ; Walker, DW; Yan, EB; Yawno, T | 1 |
| Cibula, D; Fait, T; Hill, M; Kancheva, L; Kancheva, R; Parízek, A; Stárka, L; Vceláková, H; Vrbíková, J | 1 |
| Kodama, M; Kodama, T; Totani, R | 1 |
| Baillie, TA; Curstedt, T; Sjövall, J; Sjövall, K | 1 |
| Eriksson, H; Haasio, J; Korttila, K | 1 |
| Heistermann, M; Hodges, JK; Hoppen, HO; van Aarde, RJ | 1 |
| Haasio, J; Kallela, H; Korttila, K | 1 |
| Morgan, M; Powell, H; Rajah, A | 1 |
| Banner, C; Calvel, M; Corpéchot, C; Mouren, M; Prasad, VV; Sjövall, J; Touyer, G; Veltz, JN; Wehrey, C; Young, J | 1 |
| Devaud, LL; Morrow, AL; Paul, SM; Purdy, RH | 1 |
| Chavatte, PM; Rossdale, PD; Tait, AD | 1 |
| Holtan, DW; Schutzer, WE | 1 |
| Holtan, DW; Kerby, JL; Schutzer, WE | 1 |
| Hodges, JK; Jewgenow, K; Meyer, HH | 1 |
| Beard, A; Heistermann, M; Hodges, JK; van Aarde, RJ | 1 |
| Heesch, CM; Masilamani, S | 1 |
| Feltz, P; Poisbeau, P; Schlichter, R | 1 |
| Baker, RE; Bicknell, RJ; Brussaard, AB; Herbison, AE; Kits, KS; Leyting-Vermeulen, JW; Smit, AB; Voorn, P; Willems, WP | 1 |
| Blaskey, LG; Zimmerberg, B | 1 |
| Kellogg, CK; Olson, VG; Pleger, GL | 1 |
| Chatterton, R; Klock, SC; Milad, MP; Moses, S | 1 |
| Biggio, G; Concas, A; Floris, S; Follesa, P; Mostallino, MC; Tuligi, G | 1 |
| Bayon, LE; Frye, CA | 3 |
| Barbaccia, ML; Biggio, G; Concas, A; Follesa, P; Grisenti, P; Mostallino, MC; Porcu, P; Purdy, RH; Trabucchi, M | 1 |
| Jerat, S; Kaufman, S | 1 |
| Deng, Y; Kaufman, S | 1 |
| Brussaard, AB; Devay, P; Kits, KS; Leyting-Vermeulen, JL | 1 |
| Hirst, JJ; Nicol, MB; Walker, D | 1 |
| Fiess, M; Heistermann, M; Hodges, JK | 1 |
| Brussaard, AB; Kits, KS | 1 |
| Barbaccia, ML; Biggio, G; Concas, A; Follesa, P; Purdy, RH | 1 |
| Brussaard, AB; Kits, KS; Lodder, JC; Wossink, J | 1 |
| Barañao, JL; Colman-Lerner, AA; Fiszman, ML; Pomata, PE | 1 |
| Egodagamage, KC; Hirst, JJ; Walker, DW | 1 |
| Beart, PM; Crossley, KJ; Hirst, JJ; Walker, DW | 1 |
| Benedetto, C; Bernardi, F; Fadalti, M; Genazzani, AR; Luisi, M; Luisi, S; Nappi, RE; Petraglia, F; Reis, FM | 1 |
| Anikijenko, P; Hirst, JJ; Mendis, S; Petratos, S; Walker, DW | 1 |
| Allison, CM; Pearson Murphy, BE | 1 |
| Murphy, BE | 1 |
| Bicíková, M; Cegan, A; Cibula, D; Fait, T; Hampl, R; Havlíková, H; Hill, M; Klak, J; Parízek, A; Stárka, L; Sulcová, J | 1 |
| Bader, JA; Bergeron, D; Champigny, C; Giguère, V; Kunath, T; Lapointe, L; Rossant, J; Tremblay, GB | 1 |
| Fujii, E; Mellon, SH | 1 |
| Bicíková, M; Cegan, A; Cibula, D; Fajt, T; Hampl, R; Havlíková, H; Hill, M; Klak, J; Meloun, M; Parízek, A; Stárka, L; Sulcová, J | 1 |
| Kamernitskii, AV; Kareva, EN; Kirpichnikova, NV; Kulikova, LE; Levina, IS; Podval'nyuk, VV | 1 |
| Acevedo, JL; DuBois, DW; Frye, GD; Hsiao, SH; Smith, KR; West, JR | 1 |
| Herbison, AE | 1 |
| Grobin, AC; Morrow, AL | 1 |
| Bicíková, M; Calda, P; Hampl, R; Hill, M; Klak, J; Zizka, Z | 1 |
| Cecchi, L; Frye, CA; Kehoe, P; Mallinson, K; McCormick, CM | 1 |
| Athey, B; Chen, GT; Gant, NF; Macdonald, PC; Milewich, L; Prough, RA; Schwarz, BE | 1 |
| Chen, GT; Gant, NF; Macdonald, PC; Milewich, L; Schwarz, BE | 3 |
| Connolly, TM; Kohl, KH; Lichtwald, K; Vecsei, P | 1 |
| Fink, G; Sarkar, DK | 1 |
| Atkins, DT; Fleeger, JL; Harms, PG; Seamans, KW | 1 |
| Hackett, AJ; Tsang, CP | 1 |
| Goswami, SV; Lamba, V; Sundararaj, BI | 1 |
| Mickan, H; Zander, J | 3 |
| Chang, MC; Lau, IF; Parkening, TA; Saksena, SK | 1 |
| Beyer, C; Bondani, A; Kubli-Garfias, C; Medrano-Conde, L | 1 |
| Dhont, M; Thiery, M; Vandekerchkhove, D; Vanluchene, E | 1 |
| Cawood, ML; Heys, RF; Oakey, RE | 1 |
| Holzbauer, M | 1 |
| Baillie, TA; Sjövall, J; Sjövall, K | 1 |
| Armstrong, DT; Hixon, JE; Kraemer, MA | 1 |
| Liu, ZH; Wu, JT | 1 |
| Anderson, RA; Axelson, M; Baillie, TA; Cronholm, T; Sjövall, J; Sjövall, K | 1 |
| Falkay, G; Ford-Rice, F; Majewska, MD | 1 |
| Baulieu, EE; Falkay, G; Majewska, MD | 1 |
| Fennessey, PV; Murphy, BE; Philip, A; Pike, AW | 1 |
| Baker, K; Bevan, BR; Jenkins, JM; Pennington, GW; Savvas, M; Taylor, NF | 1 |
| Heger, W; Neubert, D | 1 |
| Heger, W; Hoyer, GA; Neubert, D | 1 |
| Heger, W; Meister, R; Merker, HJ; Neubert, D; Sames, K | 1 |
| Wu, JT | 1 |
29 review(s) available for pregnanolone and Pregnancy
| Article | Year |
|---|---|
Brexanolone for Postpartum Depression: Clinical Evidence and Practical Considerations.
Topics: Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; GABA Modulators; Humans; Pregnancy; Pregnanolone; Psychiatric Status Rating Scales; Severity of Illness Index | 2019 |
Brexanolone for postpartum depression.
Topics: Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Pregnancy; Pregnanolone; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Risk Evaluation and Mitigation; Severity of Illness Index | 2020 |
Postpartum Depression: Identification and Treatment in the Clinic Setting.
Topics: Adult; Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Infant; Mass Screening; Neurosteroids; Perinatal Care; Postpartum Period; Pregnancy; Pregnanolone; Prevalence; Psychiatric Status Rating Scales; Psychotherapy; Risk Factors; Selective Serotonin Reuptake Inhibitors; Surveys and Questionnaires | 2020 |
Progesterone and fetal-neonatal neuroprotection.
Topics: Animals; Female; Fetus; Humans; Infant, Newborn; Mice; Neuroprotection; Pregnancy; Pregnanolone; Premature Birth; Progesterone; Rats; Sheep | 2020 |
Brexanolone: A Novel Drug for the Treatment of Postpartum Depression.
Topics: beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Pregnancy; Pregnanolone; Unconsciousness | 2022 |
Review of Allopregnanolone Agonist Therapy for the Treatment of Depressive Disorders.
Topics: Antidepressive Agents; beta-Cyclodextrins; Bipolar Disorder; Depression, Postpartum; Depressive Disorder; Drug Combinations; Female; Humans; Pregnancy; Pregnanes; Pregnanolone; Psychiatric Status Rating Scales; Pyrazoles | 2021 |
Is fetal analgesia necessary during prenatal surgery?
Topics: Adenosine; Analgesia; Anesthesia; Arousal; Female; Fetal Blood; Fetus; Gestational Age; Humans; MEDLINE; Nervous System; Pain; Pain Management; Pregnancy; Pregnanolone; Prostaglandin D2 | 2018 |
Allopregnanolone involvement in feeding regulation, overeating and obesity.
Topics: Animals; Female; gamma-Aminobutyric Acid; Humans; Hyperphagia; Obesity; Polycystic Ovary Syndrome; Pregnancy; Pregnanolone; Receptors, GABA-A | 2018 |
Predictors of Postpartum Depression: A Comprehensive Review of the Last Decade of Evidence.
Topics: beta-Endorphin; Biomarkers; C-Reactive Protein; Corticotropin-Releasing Hormone; Depression, Postpartum; Epigenesis, Genetic; Female; Genetic Predisposition to Disease; Humans; Hydrocortisone; Interleukin-6; Life Change Events; Maternal Age; Mental Disorders; Oxytocin; Pregnancy; Pregnanolone; Premature Birth; Race Factors; Risk Factors; Social Class; Thyroid Function Tests | 2018 |
Neuroactive Steroids and Perinatal Depression: a Review of Recent Literature.
Topics: Depression; Depression, Postpartum; Female; Humans; Pregnancy; Pregnancy Complications; Pregnanolone | 2018 |
Brain intracrinology of allopregnanolone during pregnancy and hormonal contraception.
Topics: Brain; Contraceptive Agents, Female; Female; Fetal Development; Humans; Maternal Exposure; Organogenesis; Pregnancy; Pregnanolone; Progestins | 2019 |
Neuroactive steroids in pregnancy: key regulatory and protective roles in the foetal brain.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Brain; Female; Fetus; GABAergic Neurons; Humans; Infant, Newborn; Nerve Growth Factors; Neuroprotective Agents; Placenta; Pregnancy; Pregnanolone; Premature Birth; Progesterone; Stress, Physiological | 2014 |
Advances in neurosteroids: role in clinical practice.
Topics: Affect; Aging; Behavior; Brain Injuries; Cognition; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Male; Menopause; Neurotransmitter Agents; Postpartum Period; Pregnancy; Pregnanolone; Premenstrual Syndrome; Progesterone; Reproduction | 2013 |
Allopregnanolone in the brain: protecting pregnancy and birth outcomes.
Topics: Animals; Brain; Female; Fetus; Humans; Pregnancy; Pregnancy Outcome; Pregnanolone | 2014 |
Allopregnanolone as a mediator of affective switching in reproductive mood disorders.
Topics: Adult; Affect; Depression, Postpartum; Female; Humans; Mood Disorders; Neurotransmitter Agents; Pregnancy; Pregnanolone; Premenstrual Syndrome | 2014 |
The role of reproductive hormones in postpartum depression.
Topics: Animals; Depression, Postpartum; Estrogens; Female; Humans; Pregnancy; Pregnanolone; Progesterone | 2015 |
Neuroactive steroids and stress axis regulation: Pregnancy and beyond.
Topics: Animals; Brain; Female; Humans; Hypothalamo-Hypophyseal System; Neurotransmitter Agents; Pituitary-Adrenal System; Pregnancy; Pregnanolone; Stress, Physiological | 2016 |
Loss of neurosteroid-mediated protection following stress during fetal life.
Topics: Animals; Brain; Female; Fetus; Humans; Infant, Newborn; Neurotransmitter Agents; Pregnancy; Pregnanolone; Premature Birth; Receptors, GABA-A; Signal Transduction; Stress, Physiological | 2016 |
The fetal brain: role of progesterone and allopregnanolone.
Topics: Brain; Female; Fetal Blood; Humans; Neurogenesis; Pregnancy; Pregnanolone; Progesterone | 2016 |
GABA(A) receptor function and gene expression during pregnancy and postpartum.
Topics: Animals; Cholestenone 5 alpha-Reductase; Female; Finasteride; Gene Expression; Hippocampus; Models, Biological; Postpartum Period; Pregnancy; Pregnancy, Animal; Pregnanolone; Progesterone; Rats; Receptors, GABA-A | 2009 |
Plasticity and function of extrasynaptic GABA(A) receptors during pregnancy and after delivery.
Topics: 5-alpha Reductase Inhibitors; Animals; Brain; Female; Finasteride; Gene Expression Regulation, Developmental; Hippocampus; Membrane Potentials; Neuronal Plasticity; Neurons; Postpartum Period; Pregnancy; Pregnancy, Animal; Pregnanolone; Progesterone; Rats; Receptors, GABA-A; Synaptic Transmission | 2009 |
Neurosteroids' effects and mechanisms for social, cognitive, emotional, and physical functions.
Topics: Affect; Alzheimer Disease; Animals; Brain; Cognition; Disease Models, Animal; Emotions; Female; Humans; Neurotransmitter Agents; Pregnancy; Pregnanolone; Sexual Behavior, Animal; Social Behavior | 2009 |
Allopregnanolone and suppressed hypothalamo-pituitary-adrenal axis stress responses in late pregnancy in the rat.
Topics: Adrenocorticotropic Hormone; Analgesics, Opioid; Animals; beta-Endorphin; Corticosterone; Corticotropin-Releasing Hormone; Estradiol; Female; Hypothalamo-Hypophyseal System; Interleukin-1beta; Norepinephrine; Paraventricular Hypothalamic Nucleus; Pituitary-Adrenal System; Pregnancy; Pregnancy, Animal; Pregnanolone; Progesterone; Rats; Stress, Physiological | 2011 |
Tolerance to allopregnanolone with focus on the GABA-A receptor.
Topics: Animals; Drug Tolerance; Female; gamma-Aminobutyric Acid; Gonadal Steroid Hormones; Humans; Pregnancy; Pregnanolone; Progesterone; Rats; Receptors, GABA-A; RNA, Messenger; Stress, Psychological; Substance Withdrawal Syndrome; Time Factors | 2011 |
GABA receptors, progesterone and premenstrual dysphoric disorder.
Topics: Animals; Brain; Female; Humans; Menstrual Cycle; Pregnancy; Pregnanolone; Premenstrual Syndrome; Progesterone; Receptors, GABA | 2003 |
Modulation of GABA(A) receptor gene expression by allopregnanolone and ethanol.
Topics: Animals; Brain; Ethanol; Female; Gene Expression Regulation; Humans; Lactation; Neuronal Plasticity; Pregnancy; Pregnanolone; Pseudopregnancy; Receptors, GABA-A | 2004 |
Stress in pregnancy activates neurosteroid production in the fetal brain.
Topics: Animals; Asphyxia; Brain; Female; Fetus; Hypoxia, Brain; Pregnancy; Pregnanolone; Prenatal Injuries; Receptors, GABA-A; Stress, Psychological | 2006 |
Neuroactive steroid modulators of the stress response.
Topics: Adrenalectomy; Alcoholism; Animals; Bridged Bicyclo Compounds, Heterocyclic; Desoxycorticosterone; Estrus; Female; Flunitrazepam; Hypothalamo-Hypophyseal System; Male; Menstruation; Pregnancy; Pregnanolone; Pregnenolone; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Stress, Physiological | 1995 |
Physiological roles for the neurosteroid allopregnanolone in the modulation of brain function during pregnancy and parturition.
Topics: Animals; Brain; Female; Humans; Labor, Obstetric; Pregnancy; Pregnanolone; Receptors, GABA-A | 2001 |
6 trial(s) available for pregnanolone and Pregnancy
| Article | Year |
|---|---|
Brexanolone injection in post-partum depression: two multicentre, double-blind, randomised, placebo-controlled, phase 3 trials.
Topics: Adult; beta-Cyclodextrins; Depression, Postpartum; Double-Blind Method; Drug Combinations; Female; GABA Agonists; Humans; Injections, Intravenous; Pregnancy; Pregnancy Trimester, Third; Pregnanolone; Psychiatric Status Rating Scales; Receptors, GABA; Severity of Illness Index; Treatment Outcome; Young Adult | 2018 |
Promoter DNA methylation of farnesoid X receptor and pregnane X receptor modulates the intrahepatic cholestasis of pregnancy phenotype.
Topics: Adult; Cell Line, Tumor; Cholestasis, Intrahepatic; Constitutive Androstane Receptor; DNA Methylation; Epigenesis, Genetic; Female; Humans; Male; Multidrug Resistance-Associated Protein 2; Phenotype; Pregnancy; Pregnancy Complications; Pregnanolone; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Transcription, Genetic | 2014 |
Observational study on the stability of the psychological status during normal pregnancy and increased blood levels of neuroactive steroids with GABA-A receptor agonist activity.
Topics: Adult; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Female; Follow-Up Studies; GABA-A Receptor Agonists; Humans; Hydrocortisone; Menstrual Cycle; Neuropsychological Tests; Pregnancy; Pregnanes; Pregnanolone; Progesterone; Prospective Studies; Psychiatric Status Rating Scales; Psychometrics; Receptors, GABA-A; Reference Values; Stress, Psychological | 2006 |
Comparison of eltanolone and thiopental in anaesthesia for termination of pregnancy.
Topics: Abortion, Induced; Adolescent; Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthesia, Obstetrical; Anesthetics, Intravenous; Eye Movements; Female; Humans; Middle Aged; Muscle, Skeletal; Orientation; Patient Discharge; Posture; Pregnancy; Pregnanolone; Psychomotor Performance; Thiopental | 1995 |
Comparison of eltanolone and propofol in anesthesia for termination of pregnancy.
Topics: Abortion, Induced; Adolescent; Adult; Anesthesia, Obstetrical; Female; Humans; Middle Aged; Pregnancy; Pregnanolone; Propofol | 1994 |
Serum allopregnanolone levels in pregnant women: changes during pregnancy, at delivery, and in hypertensive patients.
Topics: Adult; Delivery, Obstetric; Female; Fetal Blood; Humans; Hypertension; Labor, Obstetric; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnanolone; Progesterone; Time Factors | 2000 |
164 other study(ies) available for pregnanolone and Pregnancy
| Article | Year |
|---|---|
Pregnant women with more seizures have lower allopregnanolone concentrations.
Topics: Animals; Female; Humans; Neurons; Pregnancy; Pregnanolone; Pregnant Women; Seizures | 2021 |
Neurosteroid-based intervention using Ganaxolone and Emapunil for improving stress-induced myelination deficits and neurobehavioural disorders.
Topics: Animals; Demyelinating Diseases; Female; Guinea Pigs; Male; Mental Disorders; Nervous System Diseases; Neuropsychological Tests; Neurosteroids; Pregnancy; Pregnanolone; Prenatal Exposure Delayed Effects; Purines; Stress, Psychological | 2021 |
Allopregnanolone and depression and anxiety symptoms across the peripartum: an exploratory study.
Topics: Anxiety; Depression; Depression, Postpartum; Female; Humans; Peripartum Period; Pregnancy; Pregnanolone; Psychiatric Status Rating Scales | 2022 |
Gestational weight gain, appetite regulating hormones, and metformin treatment in polycystic ovary syndrome: A longitudinal, placebo-controlled study.
Topics: Appetite; Body Mass Index; Cohort Studies; Female; Gestational Weight Gain; Ghrelin; Humans; Leptin; Metformin; Polycystic Ovary Syndrome; Pregnancy; Pregnanolone; Prospective Studies; Randomized Controlled Trials as Topic | 2022 |
Implementation of a Hospital-based Brexanolone Program.
Topics: beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Hospitals; Humans; Pregnancy; Pregnanolone | 2022 |
Neuroactive steroids - new possibilities in the treatment of postpartum depression.
Topics: Depression, Postpartum; Female; Humans; Neurosteroids; Pregnancy; Pregnanolone; Receptors, GABA; Sertraline | 2022 |
Paeoniflorin exhibits antidepressant activity in rats with postpartum depression via the TSPO and BDNF‑mTOR pathways.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Carrier Proteins; Corticosterone; Depression; Depression, Postpartum; Disease Models, Animal; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Fluoxetine; Glucosides; Hippocampus; Humans; Monoterpenes; Pregnancy; Pregnanolone; Progesterone; Rats; Receptors, GABA-A; Stress, Psychological; Sucrose; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha | 2022 |
Validation of a Commercial Enzyme-Linked Immunosorbent Assay for Allopregnanolone in the Saliva of Healthy Pregnant Women.
Topics: Enzyme-Linked Immunosorbent Assay; Female; Hormones; Humans; Neurosteroids; Pregnancy; Pregnanolone; Pregnant Women; Saliva; Tandem Mass Spectrometry | 2022 |
Lack of placental neurosteroid alters cortical development and female somatosensory function.
Topics: Adolescent; Female; Humans; Infant, Newborn; Infant, Premature; Male; Neurosteroids; Placenta; Pregnancy; Pregnanolone; Receptors, GABA-A | 2022 |
The impact of the ovarian cycle on anxiety, allopregnanolone, and corticotropin releasing hormone changes after motherhood in female rats and women.
Topics: Animals; Anxiety; Corticotropin-Releasing Hormone; Estrous Cycle; Female; Humans; Menstrual Cycle; Pregnancy; Pregnanolone; Rats; Receptors, GABA-A | 2023 |
Metabolites of progesterone in pregnancy: Associations with perinatal anxiety.
Topics: 5-alpha-Dihydroprogesterone; Anxiety Disorders; Cross-Sectional Studies; Female; Humans; Neurosteroids; Pregnancy; Pregnanolone; Progesterone | 2023 |
Reproductive experience alters the effects of diazepam and fluoxetine on anxiety-like behaviour, fear extinction, and corticosterone levels in female rats.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Corticosterone; Diazepam; Estradiol; Extinction, Psychological; Fear; Female; Fluoxetine; Humans; Pregnancy; Pregnanolone; Progesterone; Rats | 2023 |
Brexanolone For Postpartum Depression: A Novel Approach and a Call for Comprehensive Postpartum Care.
Topics: Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Neurosteroids; Postpartum Period; Pregnancy; Pregnanolone | 2020 |
Cost-Effectiveness of Brexanolone Versus Selective Serotonin Reuptake Inhibitors for the Treatment of Postpartum Depression in the United States.
Topics: Adolescent; Adult; beta-Cyclodextrins; Cost-Benefit Analysis; Depression, Postpartum; Drug Combinations; Female; Humans; Pregnancy; Pregnanolone; Prenatal Care; Psychometrics; Quality-Adjusted Life Years; Selective Serotonin Reuptake Inhibitors; United States; Young Adult | 2020 |
Longitudinal proneuroactive and neuroactive steroid profiles in medication-free women with, without and at-risk for perinatal depression: A liquid chromatography-tandem mass spectrometry analysis.
Topics: 20-alpha-Dihydroprogesterone; Adult; Anxiety; Chromatography, Liquid; Depression; Depression, Postpartum; Depressive Disorder; Desoxycorticosterone; Female; Humans; Longitudinal Studies; Neurosteroids; Parturition; Pregnancy; Pregnanolone; Pregnenolone; Prenatal Care; Progesterone; Prospective Studies; Risk Factors; Tandem Mass Spectrometry | 2020 |
Effects of prenatal stress on behavioural and neurodevelopmental outcomes are altered by maternal separation in the neonatal period.
Topics: Animals; Female; Glutamates; Guinea Pigs; Hippocampus; Hydrocortisone; Male; Maternal Deprivation; Neurosteroids; Pregnancy; Pregnanolone; Prenatal Exposure Delayed Effects; Receptors, GABA-A | 2021 |
Evaluating brexanolone for the treatment of postpartum depression.
Topics: beta-Cyclodextrins; Child; Depression, Postpartum; Drug Combinations; Female; Humans; Pregnancy; Pregnanolone | 2021 |
Prenatal Exposure to Bisphenols and Phthalates and Postpartum Depression: The Role of Neurosteroid Hormone Disruption.
Topics: Adult; Benzhydryl Compounds; Depression, Postpartum; Endocrine Disruptors; Female; Humans; Maternal Exposure; Neurosteroids; Phenols; Phthalic Acids; Postpartum Period; Pregnancy; Pregnancy Trimesters; Pregnanolone; Pregnenolone; Progesterone; Prospective Studies; Psychiatric Status Rating Scales | 2021 |
Neurosteroid involvement in threatened preterm labour.
Topics: Adolescent; Adult; Biomarkers; Body Mass Index; Brain; Female; Humans; Male; Obstetric Labor, Premature; Oxytocin; Pregnancy; Pregnanolone; Progesterone; Receptors, GABA-A; Risk; Saccades; Young Adult | 2021 |
A preliminary study on the mechanism of the neurosteroid-mediated ionotropic receptor dysfunction in neurodevelopmental toxicity induced by decabromodiphenyl ether.
Topics: Animals; Brain; Cholesterol Side-Chain Cleavage Enzyme; Cyclic AMP Response Element-Binding Protein; Female; Halogenated Diphenyl Ethers; Lactation; Male; Mice; Mice, Inbred ICR; Nervous System; Neurons; Neurosteroids; Pregnancy; Pregnanolone; Progesterone; Receptors, GABA; Steroid 17-alpha-Hydroxylase | 2021 |
Development and validation of an LC-MS/MS assay for the quantification of allopregnanolone and its progesterone-derived isomers, precursors, and cortisol/cortisone in pregnancy.
Topics: Chromatography, High Pressure Liquid; Cortisone; Female; Humans; Hydrocortisone; Isomerism; Limit of Detection; Pregnancy; Pregnanolone; Progesterone; Tandem Mass Spectrometry | 2021 |
Placental endocrine function shapes cerebellar development and social behavior.
Topics: Aldehyde Reductase; Animals; Autism Spectrum Disorder; Cerebellum; Endocrine Glands; Female; GABA Agonists; GABA Modulators; Gene Deletion; Humans; Infant; Infant, Newborn; Male; Mice; Muscimol; Placenta; Pregnancy; Pregnanolone; Receptors, GABA-A; Sex Characteristics; Social Behavior; Trophoblasts; White Matter | 2021 |
Effects of combined IUGR and prenatal stress on the development of the hippocampus in a fetal guinea pig model.
Topics: Animals; Disease Models, Animal; Female; Fetal Development; Fetal Growth Retardation; Guinea Pigs; Hippocampus; Hydrocortisone; Pregnancy; Pregnancy Complications; Pregnanolone; Prenatal Exposure Delayed Effects; Stress, Psychological | 2017 |
Juvenile social isolation affects maternal care in rats: involvement of allopregnanolone.
Topics: Animals; Anxiety; Corticosterone; Disease Models, Animal; Female; Maternal Behavior; Pregnancy; Pregnanolone; Rats; Rats, Sprague-Dawley; Social Isolation; Weaning | 2017 |
Administration of Progesterone Throughout Pregnancy Increases Maternal Steroids Without Adverse Effect on Mature Oligodendrocyte Immunostaining in the Guinea Pig.
Topics: Animals; Brain; Female; Fetal Development; Guinea Pigs; Hydrocortisone; Myelin Sheath; Oligodendroglia; Pregnancy; Pregnanolone; Progesterone | 2018 |
Allopregnanolone levels and depressive symptoms during pregnancy in relation to single nucleotide polymorphisms in the allopregnanolone synthesis pathway.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adult; Depression; Depression, Postpartum; Female; Genetic Association Studies; Humans; Hydroxysteroid Dehydrogenases; Membrane Proteins; Metabolic Networks and Pathways; Oxidoreductases; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications; Pregnanolone; Psychiatric Status Rating Scales | 2017 |
Maternal stress in pregnancy affects myelination and neurosteroid regulatory pathways in the guinea pig cerebellum.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Anxiety; Astrocytes; Behavior, Animal; Cerebellum; Female; Fetus; Guinea Pigs; Male; Neurotransmitter Agents; Oligodendroglia; Pregnancy; Pregnancy Complications; Pregnanolone; Prenatal Exposure Delayed Effects; Receptors, GABA-A; RNA, Messenger; Stress, Psychological | 2017 |
Combined effect of gestational stress and postpartum stress on maternal care in rats.
Topics: Age Factors; Animals; Animals, Newborn; Corticosterone; Female; Grooming; Maternal Behavior; Maternal Deprivation; Postpartum Period; Posture; Pregnancy; Pregnanolone; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Stress, Psychological | 2018 |
Pharmacological rescue of nociceptive hypersensitivity and oxytocin analgesia impairment in a rat model of neonatal maternal separation.
Topics: Action Potentials; Analgesics; Animals; Animals, Newborn; Antidiuretic Hormone Receptor Antagonists; Carrageenan; Female; Gene Expression Regulation; Histone Deacetylase Inhibitors; Hypersensitivity; Male; Maternal Deprivation; Nociception; Oxytocin; Pain; Pain Threshold; Posterior Horn Cells; Pregnancy; Pregnanolone; Rats; Rats, Wistar; Signal Transduction; Vasotocin; Vorinostat | 2018 |
GABA
Topics: Adult; beta-Cyclodextrins; Depression, Postpartum; Depressive Disorder, Major; Drug Combinations; Female; Humans; Mood Disorders; Neurotransmitter Agents; Postpartum Period; Pregnancy; Pregnanolone; Prevalence; Receptors, GABA-A | 2019 |
Enhanced remyelination during late pregnancy: involvement of the GABAergic system.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Animals; Bicuculline; Corpus Callosum; Demyelinating Diseases; Disease Models, Animal; Female; Finasteride; GABA Antagonists; Lysophosphatidylcholines; Male; Microglia; Multiple Sclerosis; Myelin Proteins; Myelin Sheath; Nerve Tissue Proteins; Oligodendrocyte Precursor Cells; Oligodendroglia; Pregnancy; Pregnancy Complications; Pregnanolone; Puerperal Disorders; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Remyelination | 2019 |
Brexanolone (Zulresso) for postpartum depression.
Topics: beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Pregnancy; Pregnanolone; Receptors, GABA-A | 2019 |
GABAergic neuroactive steroids and resting-state functional connectivity in postpartum depression: a preliminary study.
Topics: Adult; Amygdala; Depression, Postpartum; Female; Gyrus Cinguli; Hippocampus; Humans; Magnetic Resonance Imaging; Nerve Net; Pilot Projects; Postpartum Period; Prefrontal Cortex; Pregnancy; Pregnanolone; Pregnenolone | 2013 |
Changes in neuroactive steroid concentrations after preterm delivery in the Guinea pig.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Animals, Newborn; Birth Weight; Brain; Disease Models, Animal; Female; Gestational Age; Glial Fibrillary Acidic Protein; Guinea Pigs; Hydrocortisone; Male; Microtubule-Associated Proteins; Myelin Basic Protein; Myelin Sheath; Neuroglia; Neurons; Pregnancy; Pregnanolone; Premature Birth; Progesterone; Steroids | 2013 |
Effects of prenatal stress on fetal neurodevelopment and responses to maternal neurosteroid treatment in Guinea pigs.
Topics: Animals; Brain; Female; Fetal Development; Glial Fibrillary Acidic Protein; Guinea Pigs; Hydrocortisone; Male; Myelin Basic Protein; Pregnancy; Pregnanolone; Prenatal Exposure Delayed Effects; Sex Factors; Stress, Psychological | 2013 |
Low serum allopregnanolone is associated with symptoms of depression in late pregnancy.
Topics: Adult; Anxiety; Depression; Depression, Postpartum; Female; Humans; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Third; Pregnanolone; Self Report; Young Adult | 2014 |
The effects of betamethasone on allopregnanolone concentrations and brain development in preterm fetal sheep.
Topics: Anesthetics; Animals; Betamethasone; Blood Chemical Analysis; Brain; Catheters, Indwelling; Female; Glucocorticoids; Oligodendroglia; Placenta; Pregnancy; Pregnanediones; Pregnanolone; Progesterone; Sheep, Domestic | 2014 |
5α-Reduced neurosteroids sex-dependently reverse central prenatal programming of neuroendocrine stress responses in rats.
Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androstane-3,17-diol; Animals; Female; Hypothalamo-Hypophyseal System; Interleukin-1beta; Male; Paraventricular Hypothalamic Nucleus; Pituitary-Adrenal System; Pregnancy; Pregnancy Complications; Pregnanolone; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sex Factors; Solitary Nucleus; Stress, Psychological | 2015 |
Postnatal administration of allopregnanolone modifies glutamate release but not BDNF content in striatum samples of rats prenatally exposed to ethanol.
Topics: Alcohol Drinking; Animals; Brain-Derived Neurotrophic Factor; Corpus Striatum; Ethanol; Female; Glutamic Acid; Male; Pregnancy; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2015 |
Progesterone metabolites as farnesoid X receptor inhibitors.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cholestasis, Intrahepatic; Cholic Acids; Female; Homeostasis; Humans; Organic Anion Transporters, Sodium-Dependent; Pregnancy; Pregnancy Complications; Pregnanolone; Progesterone; Receptors, Cytoplasmic and Nuclear; Symporters | 2015 |
Allopregnanolone and social stress: regulation of the stress response in early pregnancy in pigs.
Topics: Adrenocorticotropic Hormone; Anesthetics; Animals; Behavior, Animal; Corticotropin-Releasing Hormone; Female; Hydrocortisone; Pregnancy; Pregnancy, Animal; Pregnanediones; Pregnanolone; Progesterone; Social Environment; Stress, Psychological; Sus scrofa; Swine | 2015 |
Replication of Epigenetic Postpartum Depression Biomarkers and Variation with Hormone Levels.
Topics: Adult; Depression, Postpartum; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Estradiol; Female; Genetic Markers; Humans; Nerve Tissue Proteins; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Pregnancy; Pregnanolone; Progesterone | 2016 |
The dynamic steroid landscape of equine pregnancy mapped by mass spectrometry.
Topics: 20-alpha-Dihydroprogesterone; Animals; Biomarkers; Chromatography, Liquid; Corpus Luteum; Female; Horses; Placenta; Pregnancy; Pregnancy, Animal; Pregnanolone; Pregnenolone; Progesterone; Steroids; Tandem Mass Spectrometry | 2016 |
Blunted neuroactive steroid and HPA axis responses to stress are associated with reduced sleep quality and negative affect in pregnancy: a pilot study.
Topics: Adrenocorticotropic Hormone; Adult; Affect; Female; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Pilot Projects; Pituitary-Adrenal System; Pregnancy; Pregnanolone; Progesterone; Sleep; Stress, Psychological; Young Adult | 2016 |
Severity and timing: How prenatal stress exposure affects glial developmental, emotional behavioural and plasma neurosteroid responses in guinea pig offspring.
Topics: Animals; Anxiety; Behavior, Animal; Brain; Emotions; Female; Fetal Development; Guinea Pigs; Hippocampus; Neurogenesis; Neuroglia; Neurotransmitter Agents; Pregnancy; Pregnanolone; Prenatal Exposure Delayed Effects; Random Allocation; Stress, Physiological; Stress, Psychological | 2016 |
Peripartum neuroactive steroid and γ-aminobutyric acid profiles in women at-risk for postpartum depression.
Topics: 20-alpha-Dihydroprogesterone; Adult; Case-Control Studies; Depression, Postpartum; Desoxycorticosterone; Female; gamma-Aminobutyric Acid; Humans; Longitudinal Studies; Peripartum Period; Pregnancy; Pregnanolone; Progesterone; Receptors, GABA-A; Risk Factors; Steroids | 2016 |
Increased anxiety-like phenotype in female guinea pigs following reduced neurosteroid exposure in utero.
Topics: 5-alpha Reductase Inhibitors; Animals; Animals, Newborn; Anxiety; Brain; Disease Models, Animal; Exploratory Behavior; Female; Finasteride; Guinea Pigs; Hydrocortisone; Nerve Tissue Proteins; Neurotransmitter Agents; Pregnancy; Pregnanolone; Prenatal Exposure Delayed Effects; Radioimmunoassay; Sex Factors; Statistics, Nonparametric | 2017 |
Lower allopregnanolone during pregnancy predicts postpartum depression: An exploratory study.
Topics: Adolescent; Adult; Depression, Postpartum; Female; Humans; Middle Aged; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, Third; Pregnanolone; Progesterone; Young Adult | 2017 |
Brain allopregnanolone in the fetal and postnatal rat in response to uteroplacental insufficiency.
Topics: Animals; Animals, Newborn; Brain; Female; Fetal Growth Retardation; Fetus; Hypoxia, Brain; Ligation; Placental Circulation; Placental Insufficiency; Pregnancy; Pregnancy, Animal; Pregnanolone; Rats; Rats, Inbred WKY | 2008 |
Allopregnanolone-induced rise in intracellular calcium in embryonic hippocampal neurons parallels their proliferative potential.
Topics: Anesthetics; Animals; Bicuculline; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Proliferation; Cells, Cultured; Cytoplasm; Female; GABA Antagonists; Hippocampus; Neurons; Nifedipine; Picrotoxin; Pregnancy; Pregnanolone; Rats; Rats, Sprague-Dawley; Review Literature as Topic | 2008 |
Central opioid inhibition of neuroendocrine stress responses in pregnancy in the rat is induced by the neurosteroid allopregnanolone.
Topics: 20-alpha-Dihydroprogesterone; Adrenocorticotropic Hormone; Analgesics, Opioid; Analysis of Variance; Anesthetics; Animals; Chromatography, Thin Layer; Corticosterone; Corticotropin-Releasing Hormone; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Finasteride; Hypothalamo-Hypophyseal System; Interleukin-1beta; Neural Inhibition; Neurons; Oxidoreductases; Paraventricular Hypothalamic Nucleus; Pituitary-Adrenal System; Pregnancy; Pregnancy, Animal; Pregnanolone; Progesterone; Progestins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stress, Physiological; Time Factors | 2009 |
Effects of gestational allopregnanolone administration in rats bred for high affective behavior.
Topics: Analysis of Variance; Anesthetics; Animals; Animals, Newborn; Disease Models, Animal; Female; Male; Maternal Behavior; Maze Learning; Mood Disorders; Pregnancy; Pregnanolone; Prenatal Exposure Delayed Effects; Rats; Sexual Behavior, Animal; Swimming; Vocalization, Animal | 2010 |
Role of neurosteroids in regulating cell death and proliferation in the late gestation fetal brain.
Topics: Animals; Apoptosis; Brain; Cell Death; Cell Proliferation; Cerebellum; Cholestenone 5 alpha-Reductase; Embryo, Mammalian; Female; Finasteride; Gestational Age; Hippocampus; Neurotransmitter Agents; Pregnancy; Pregnanediones; Pregnanolone; Sheep | 2009 |
Excitability changes related to GABAA receptor plasticity during pregnancy.
Topics: Action Potentials; Animals; Brain; Down-Regulation; Female; Hippocampus; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuronal Plasticity; Neurons; Potassium Chloride; Pregnancy; Pregnanolone; Receptors, GABA-A; Synaptic Transmission | 2009 |
Surgical management of placenta accreta: a cohort series and suggested approach.
Topics: Adolescent; Adult; Catheterization; Delivery, Obstetric; Embolization, Therapeutic; Female; Humans; Hysterectomy; Iliac Artery; Length of Stay; Middle Aged; Placenta Accreta; Pregnancy; Pregnanolone; Radiography, Interventional; Retrospective Studies; Ultrasonography, Doppler, Duplex; Young Adult | 2010 |
The effect of betamethasone treatment on neuroactive steroid synthesis in a foetal Guinea pig model of growth restriction.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Betamethasone; Brain; Female; Fetal Growth Retardation; Fetus; Glial Fibrillary Acidic Protein; Glucocorticoids; Guinea Pigs; Hippocampus; Male; Placenta; Pregnancy; Pregnanolone; Sex Factors; Uterine Artery | 2010 |
Neonatal exposure to estradiol in rats influences neuroactive steroid concentrations, GABAA receptor expression, and behavioral sensitivity to anxiolytic drugs.
Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Brain Chemistry; Cerebral Cortex; Diazepam; Estradiol; Female; Immunoblotting; Motor Activity; Neurotransmitter Agents; Pregnancy; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Steroids | 2010 |
Juvenile offspring of rats exposed to restraint stress in late gestation have impaired cognitive performance and dysregulated progestogen formation.
Topics: Animals; Cognition Disorders; Corticosterone; Exploratory Behavior; Female; Male; Maternal Exposure; Prefrontal Cortex; Pregnancy; Pregnanolone; Progesterone; Progestins; Rats; Rats, Long-Evans; Restraint, Physical; Stress, Physiological | 2011 |
Sex-dependent effect of a low neurosteroid environment and intrauterine growth restriction on foetal guinea pig brain development.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Animals; Brain; Female; Fetal Development; Fetus; Finasteride; Glial Fibrillary Acidic Protein; Guinea Pigs; Male; Myelin Basic Protein; Neurotransmitter Agents; Pregnancy; Pregnanolone; Sex Factors | 2011 |
Neurosteroids for a successful pregnancy.
Topics: Animals; Central Nervous System; Female; Humans; Neurotransmitter Agents; Pregnancy; Pregnanolone; Progesterone | 2011 |
Assessment of estrus cyclicity in the Asian elephant (Elephas maximus) by measurement of fecal progesterone metabolite 5α-P-3OH, using a non-invasive assay.
Topics: Animals; Elephants; Enzyme-Linked Immunosorbent Assay; Estrous Cycle; Feces; Female; Longitudinal Studies; Pregnancy; Pregnancy, Animal; Pregnanolone; Progesterone; Reproduction | 2012 |
Allopregnanolone prevents dieldrin-induced NMDA receptor internalization and neurotoxicity by preserving GABA(A) receptor function.
Topics: Anesthetics; Animals; Cell Membrane; Cerebral Cortex; Dieldrin; Disks Large Homolog 4 Protein; Embryo, Mammalian; Endocrine Disruptors; Estradiol; Female; Gene Expression Regulation; Glutamic Acid; Guanylate Kinases; Membrane Proteins; Mice; Neurons; Pregnancy; Pregnanolone; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2012 |
Effect of maternal administration of allopregnanolone before birth asphyxia on neonatal hippocampal function in the spiny mouse.
Topics: Animals; Animals, Newborn; Asphyxia; Cell Proliferation; Female; Hippocampus; Long-Term Potentiation; Mice; Pregnancy; Pregnanolone; Prenatal Exposure Delayed Effects; Random Allocation | 2012 |
Allopregnanolone and induction of endogenous opioid inhibition of oxytocin responses to immune stress in pregnant rats.
Topics: 5-alpha Reductase Inhibitors; Animals; Drug Interactions; Female; Finasteride; Interleukin-1beta; Naloxone; Narcotic Antagonists; Opioid Peptides; Oxytocin; Paraventricular Hypothalamic Nucleus; Pituitary Gland, Posterior; Pregnancy; Pregnancy, Animal; Pregnanolone; Rats; Rats, Sprague-Dawley; Stress, Physiological; Supraoptic Nucleus | 2012 |
Regulation of the surface expression of α4β2δ GABAA receptors by high efficacy states.
Topics: Animals; Cells, Cultured; Female; GABA-A Receptor Agonists; Gene Expression Regulation; HEK293 Cells; Hippocampus; Humans; Pregnancy; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2012 |
Intrahepatic cholestasis of pregnancy levels of sulfated progesterone metabolites inhibit farnesoid X receptor resulting in a cholestatic phenotype.
Topics: Animals; Bile Acids and Salts; Cholestasis; Cholestasis, Intrahepatic; Cholic Acid; Female; Homeostasis; Humans; Mice; Mice, Inbred C57BL; Phenotype; Pregnancy; Pregnancy Complications; Pregnanolone; Progesterone; Receptors, Cytoplasmic and Nuclear; Sulfuric Acid Esters | 2013 |
Detection of pregnancy and fertility status in big cats using an enzyme immunoassay based on 5α-pregnan-3α-ol-20-one.
Topics: Animals; Animals, Wild; Felidae; Female; Immunoenzyme Techniques; Lions; Panthera; Pregnancy; Pregnancy Tests; Pregnanolone | 2013 |
Allopregnanolone attenuates N-methyl-D-aspartate-induced excitotoxicity and apoptosis in the human NT2 cell line in culture.
Topics: Apoptosis; Asphyxia Neonatorum; Benzimidazoles; Carbocyanines; Cell Count; Cell Survival; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Fluorescent Dyes; Humans; Hypoxia-Ischemia, Brain; In Situ Nick-End Labeling; Infant, Newborn; L-Lactate Dehydrogenase; Membrane Potentials; Mitochondria; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Pregnancy; Pregnanolone; Progesterone; Tumor Cells, Cultured | 2002 |
Prenatal diazepam exposure functionally alters the GABA(A) receptor that modulates [3H]noradrenaline release from rat hippocampal synaptosomes.
Topics: Allosteric Regulation; Animals; Baclofen; Bicuculline; Diazepam; Female; Fetal Proteins; GABA Agonists; GABA Antagonists; Hippocampus; Male; Mental Disorders; Nerve Tissue Proteins; Norepinephrine; Picrotoxin; Pregnancy; Pregnanolone; Prenatal Exposure Delayed Effects; Protein Subunits; Rats; Rats, Wistar; Receptors, GABA-A; Synaptosomes | 2002 |
Changes in expression of the neuropeptide Y Y1 receptor gene in the medial amygdala of transgenic mice during pregnancy and after delivery.
Topics: Amygdala; Animals; Cerebral Cortex; Desoxycorticosterone; Enzyme Inhibitors; Female; Finasteride; Gene Expression Regulation; Genes, Reporter; In Situ Hybridization; Mice; Mice, Transgenic; Postpartum Period; Pregnancy; Pregnancy, Animal; Pregnanolone; Progesterone; Receptors, Neuropeptide Y; RNA, Messenger; Transgenes | 2002 |
Female Wistar rats tested during late proestrus or during pregnancy and ovariectomized rats tested after receiving progesterone or allopregnanolone displayed reduced conflict behavior.
Topics: Animals; Choice Behavior; Conflict, Psychological; Dose-Response Relationship, Drug; Female; Ovariectomy; Pregnancy; Pregnanolone; Proestrus; Progesterone; Rats; Rats, Wistar | 2002 |
Oxytocin regulates neurosteroid modulation of GABA(A) receptors in supraoptic nucleus around parturition.
Topics: Animals; Animals, Newborn; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Female; gamma-Aminobutyric Acid; Humans; Kidney; Ligands; Male; Mice; Mice, Knockout; Mice, Transgenic; Oocytes; Oxytocin; Patch-Clamp Techniques; Phosphoprotein Phosphatases; Pregnancy; Pregnanolone; Protein Kinase C; Rats; Rats, Wistar; Receptors, GABA-A; Steroids; Supraoptic Nucleus; Transfection; Xenopus | 2003 |
Changes in 5alpha-pregnane steroids and neurosteroidogenic enzyme expression in the perinatal sheep.
Topics: Animals; Brain; Cholestenone 5 alpha-Reductase; Cholesterol Side-Chain Cleavage Enzyme; Enzyme-Linked Immunosorbent Assay; Female; Pregnancy; Pregnanolone; Sheep | 2003 |
Pregnanolone isomers, pregnenolone and their polar conjugates around parturition.
Topics: Female; Fetal Blood; Humans; Isomerism; Labor, Obstetric; Postpartum Period; Pregnancy; Pregnanolone | 2003 |
Steroid-sensitive GABAA receptors in the fetal sheep brain.
Topics: Age Factors; Animals; Brain; Dose-Response Relationship, Drug; Female; Fetus; Gestational Age; Pregnancy; Pregnanolone; Protein Binding; Receptors, GABA-A; Sheep | 2003 |
The 17, 20-lyase activity of cytochrome p450c17 from human fetal testis favors the delta5 steroidogenic pathway.
Topics: 17-alpha-Hydroxyprogesterone; Adult; Catalysis; Dehydroepiandrosterone; Female; Humans; Kinetics; Leydig Cells; Male; Microsomes; Multienzyme Complexes; Pregnancy; Pregnanolone; Pregnenolone; Progesterone; Progesterone Reductase; Steroid 17-alpha-Hydroxylase; Steroid Isomerases; Steroids; Testis | 2003 |
[CHROMATOGRAPHIC SEPARATION AND DETERMINATION OF PREGNANOLONE].
Topics: Body Fluids; Chromatography; Female; Humans; Pregnancy; Pregnanediol; Pregnanolone; Pregnenolone; Spectrophotometry; Urine | 1963 |
Chronic prenatal ethanol exposure alters hippocampal GABA(A) receptors and impairs spatial learning in the guinea pig.
Topics: Animals; Body Weight; Brain; Central Nervous System Depressants; Ethanol; Female; Flunitrazepam; GABA Modulators; Guinea Pigs; Hippocampus; Immunoblotting; Learning; Maze Learning; Motor Activity; Organ Size; Pregnancy; Pregnanolone; Prenatal Exposure Delayed Effects; Radioligand Assay; Receptors, GABA-A; Space Perception | 2004 |
Neonatal neurosteroid administration alters parvalbumin expression and neuron number in medial dorsal thalamus of adult rats.
Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Cell Count; Excitatory Amino Acid Transporter 3; Female; Glutamate Plasma Membrane Transport Proteins; Male; Mediodorsal Thalamic Nucleus; Neurons; Parvalbumins; Pregnancy; Pregnanolone; Rats; Rats, Sprague-Dawley; Symporters | 2004 |
Allopregnanolone in the brain and blood after disruption of the hypothalamic-pituitary-adrenal axis in fetal sheep.
Topics: Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Animals; Brain Chemistry; Cholesterol Side-Chain Cleavage Enzyme; Female; Fetus; Gestational Age; Hydrocortisone; Hypophysectomy; Immunoblotting; Pituitary Gland; Pregnancy; Pregnanolone; Pregnenolone; Progesterone; Radioimmunoassay; Sheep | 2004 |
Hippocampal 3alpha,5alpha-THP may alter depressive behavior of pregnant and lactating rats.
Topics: Animals; Depression; Female; Finasteride; Hippocampus; Lactation; Pregnancy; Pregnancy, Animal; Pregnanolone; Rats; Rats, Long-Evans; Swimming | 2004 |
Fetal alcohol exposure alters neurosteroid levels in the developing rat brain.
Topics: Age Factors; Animals; Animals, Newborn; Behavior, Animal; Blotting, Western; Brain; Brain Chemistry; Central Nervous System Depressants; Ethanol; Feeding Behavior; Female; Gas Chromatography-Mass Spectrometry; Liver; Male; Models, Neurological; Placenta; Pregnancy; Pregnanolone; Pregnenolone; Prenatal Exposure Delayed Effects; Radioimmunoassay; Rats; Steroids; Testosterone; Tyramine | 2004 |
Neuroactive pregnanolone isomers during pregnancy.
Topics: Estradiol; Female; Gestational Age; Humans; Isomerism; Labor, Obstetric; Pregnancy; Pregnanolone; Progesterone | 2005 |
Progesterone attenuates corticotropin-releasing factor-enhanced but not fear-potentiated startle via the activity of its neuroactive metabolite, allopregnanolone.
Topics: Acoustic Stimulation; Animals; Anxiety; Corticotropin-Releasing Hormone; Estradiol; Fear; Female; Hormone Replacement Therapy; Lactation; Medroxyprogesterone; Ovariectomy; Pregnancy; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Reflex, Startle; Septal Nuclei | 2004 |
The neurosteroid allopregnanolone promotes proliferation of rodent and human neural progenitor cells and regulates cell-cycle gene and protein expression.
Topics: Analysis of Variance; Animals; Blotting, Western; Bromodeoxyuridine; Cell Count; Cell Cycle Proteins; Cell Proliferation; Cells, Cultured; Embryo, Mammalian; Female; Flow Cytometry; Gene Expression; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Hippocampus; Humans; Immunohistochemistry; Intermediate Filament Proteins; Male; Microtubule-Associated Proteins; Myelin Basic Protein; Nerve Tissue Proteins; Nestin; Neurons; Oligonucleotide Array Sequence Analysis; Pregnancy; Pregnanolone; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stem Cells; Thymidine; Time Factors; Transfection; Tritium | 2005 |
Neuroactive steroids and ethanol.
Topics: Alcoholism; Animals; Brain; Dehydroepiandrosterone; Female; Fetal Alcohol Spectrum Disorders; Humans; Male; Menstrual Cycle; Mice; Mice, Inbred C57BL; Pregnancy; Pregnanolone; Receptors, GABA-A | 2005 |
3alpha-reduced neuroactive steroids and their precursors during pregnancy and the postpartum period.
Topics: 5-alpha-Dihydroprogesterone; Adult; Delivery, Obstetric; Depression, Postpartum; Female; Gas Chromatography-Mass Spectrometry; Gestational Age; Humans; Labor Onset; Parity; Postpartum Period; Pregnancy; Pregnanolone; Pregnenolone; Progesterone | 2005 |
Rats bred for high versus low anxiety responses neonatally demonstrate increases in lordosis, pacing behavior, and midbrain 3 alpha, 5 alpha-THP levels as adults.
Topics: Animals; Animals, Newborn; Anxiety; Behavior, Animal; Circadian Rhythm; Female; Male; Physiology; Posture; Pregnancy; Pregnanolone; Radioimmunoassay; Rats; Rats, Inbred Strains; Reaction Time; Sexual Behavior, Animal; Social Behavior; Ventral Tegmental Area | 2006 |
The anxiolytic effect of pregnancy in rats is reversed by finasteride.
Topics: 5-alpha Reductase Inhibitors; Animals; Anxiety; Corticosterone; Enzyme Inhibitors; Female; Finasteride; Pregnancy; Pregnancy, Animal; Pregnanolone; Rats; Rats, Wistar | 2006 |
Inhibition of neurosteroid synthesis increases asphyxia-induced brain injury in the late gestation fetal sheep.
Topics: Animals; Apoptosis; Asphyxia; Brain Injuries; Caspase 3; Enzyme Inhibitors; Female; Fetus; Finasteride; Gestational Age; Goats; Heart Rate; Oxygen; Pregnancy; Pregnanolone; Radioimmunoassay; Umbilical Cord | 2007 |
Relationships of circulating pregnanolone isomers and their polar conjugates to the status of sex, menstrual cycle, and pregnancy.
Topics: Adolescent; Adult; Analysis of Variance; Female; Follicular Phase; Humans; Luteal Phase; Male; Menstrual Cycle; Middle Aged; Pregnancy; Pregnancy Trimester, Third; Pregnanolone; Sex; Stereoisomerism | 2007 |
Dissociation of chorioadenoma destruens from hydatidiform mole by urinary steroid analysis.
Topics: 17-Ketosteroids; Chorionic Gonadotropin; Chromatography, Gas; Diagnosis, Differential; Female; Humans; Hydatidiform Mole; Hydatidiform Mole, Invasive; Pregnancy; Pregnanes; Pregnanolone; Uterine Neoplasms | 1981 |
Production rates and metabolism of sulphates of 3 beta-hydroxy-5 alpha-pregnane derivatives in pregnant women.
Topics: Deuterium; Female; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Kinetics; Pregnancy; Pregnanediol; Pregnanes; Pregnanolone; Radioisotope Dilution Technique; Structure-Activity Relationship | 1980 |
Progestin content and biosynthetic potential of the corpus luteum of the African elephant (Loxodonta africana).
Topics: 17-alpha-Hydroxyprogesterone; 5-alpha-Dihydroprogesterone; Animals; Chromatography, High Pressure Liquid; Corpus Luteum; Elephants; Female; Hydroxyprogesterones; Isomerism; Pregnancy; Pregnancy, Animal; Pregnanediones; Pregnanolone; Progesterone; Progestins | 1994 |
Eltanolone for induction of anaesthesia and to supplement nitrous oxide for minor gynaecological surgery.
Topics: Abortion, Therapeutic; Adolescent; Adult; Anesthesia, General; Dilatation and Curettage; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Middle Aged; Minor Surgical Procedures; Nitrous Oxide; Pregnancy; Pregnanolone; Time Factors | 1993 |
Neurosteroids: 3 alpha-hydroxy-5 alpha-pregnan-20-one and its precursors in the brain, plasma, and steroidogenic glands of male and female rats.
Topics: 5-alpha-Dihydroprogesterone; Adrenal Glands; Adrenalectomy; Animals; Brain; Female; Gas Chromatography-Mass Spectrometry; Male; Orchiectomy; Ovariectomy; Ovary; Pregnancy; Pregnanediones; Pregnanolone; Progesterone; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Testis | 1993 |
Modulation of 3 beta-hydroxysteroid dehydrogenase (3 beta-HSD) activity in the equine placenta by pregnenolone and progesterone metabolites.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Dose-Response Relationship, Drug; Female; Horses; Placenta; Pregnancy; Pregnanediol; Pregnanes; Pregnanolone; Pregnenes; Pregnenolone; Progesterone | 1995 |
Steroid transformations in pregnant mares: metabolism of exogenous progestins and unusual metabolic activity in vivo and in vitro.
Topics: 5-alpha-Dihydroprogesterone; Animals; Biotransformation; Deuterium; Endometrium; Female; Horses; In Vitro Techniques; Infusions, Intravenous; Liver; Organ Specificity; Pharmaceutical Vehicles; Placenta; Pregnancy; Pregnancy, Animal; Pregnanediones; Pregnanolone; Pregnenolone; Progestins | 1996 |
Differential effect of trilostane on the progestin milieu in the pregnant mare.
Topics: 3-Hydroxysteroid Dehydrogenases; 5-alpha-Dihydroprogesterone; Animals; Dihydrotestosterone; Female; Horses; Male; Placenta; Pregnancy; Pregnancy, Animal; Pregnanediones; Pregnanolone; Pregnenolone; Progesterone; Progestins | 1996 |
Binding activity of 5alpha-reduced gestagens to the progestin receptor from African elephant (Loxodonta africana).
Topics: 5-alpha-Dihydroprogesterone; Animals; Autopsy; Binding, Competitive; Cytosol; Dose-Response Relationship, Drug; Elephants; Endometrium; Female; Pregnancy; Pregnanediones; Pregnanolone; Pregnenediones; Progesterone; Progesterone Congeners; Progestins; Radioligand Assay; Receptors, Progesterone; Tritium; Uterus | 1997 |
Concentrations of progesterone and the 5 alpha-reduced progestins, 5 alpha-pregnane-3,20-dione and 3 alpha-hydroxy-5 alpha-pregnan-20-one, in luteal tissue and circulating blood and their relationship to luteal function in the African elephant, Loxodonta
Topics: 5-alpha-Dihydroprogesterone; Animals; Chromatography, High Pressure Liquid; Corpus Luteum; Elephants; Estrus; Female; Gestational Age; Pregnancy; Pregnanediones; Pregnanolone; Progesterone; Progestins | 1997 |
Effects of pregnancy and progesterone metabolites on arterial baroreflex in conscious rats.
Topics: Animals; Baroreflex; Blood Pressure; Female; Heart Rate; Hemodynamics; Isomerism; Kidney; Nitroprusside; Phenylephrine; Pregnancy; Pregnancy, Animal; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System | 1997 |
Modulation of GABAA receptor-mediated IPSCs by neuroactive steroids in a rat hypothalamo-hypophyseal coculture model.
Topics: Animals; Animals, Newborn; Cells, Cultured; Electrophysiology; Female; GABA Modulators; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Hypothalamo-Hypophyseal System; Membrane Potentials; Pentobarbital; Pregnancy; Pregnanes; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Receptors, GABA-A | 1997 |
Plasticity in fast synaptic inhibition of adult oxytocin neurons caused by switch in GABA(A) receptor subunit expression.
Topics: Animals; Electric Conductivity; Electrophysiology; Female; GABA Modulators; Labor, Obstetric; Neural Inhibition; Neuronal Plasticity; Neurons; Oxytocin; Pregnancy; Pregnancy, Animal; Pregnanolone; Rats; Receptors, GABA-A; RNA, Messenger; Supraoptic Nucleus; Synapses; Time Factors | 1997 |
Prenatal stress effects are partially ameliorated by prenatal administration of the neurosteroid allopregnanolone.
Topics: Animals; Anxiety; Anxiety, Separation; Female; Handling, Psychological; Male; Motor Activity; Neuroprotective Agents; Pregnancy; Pregnanolone; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Restraint, Physical; Stress, Psychological; Vocalization, Animal; Weight Gain | 1998 |
Neurosteroid action at the GABAA receptor in fetal rat forebrain.
Topics: Androsterone; Animals; Chlorides; Diazepam; Female; Fetus; GABA Modulators; gamma-Aminobutyric Acid; Male; Pregnancy; Pregnanolone; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sex Factors; Synaptosomes | 1998 |
Stress and anxiety do not result in pregnancy wastage.
Topics: Adult; Age Factors; Anxiety; Chorionic Gonadotropin; Female; Fertilization in Vitro; Humans; Infertility; Male; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pregnanolone; Progesterone; Prospective Studies; Stress, Psychological | 1998 |
Molecular and functional adaptation of the GABA(A) receptor complex during pregnancy and after delivery in the rat brain.
Topics: Allosteric Regulation; Alternative Splicing; Animals; Brain Chemistry; Cerebral Cortex; Chlorides; Diazepam; Female; Hippocampus; Isotopes; Muscimol; Postpartum Period; Pregnancy; Pregnancy, Animal; Pregnanolone; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger | 1998 |
Seizure activity is increased in endocrine states characterized by decline in endogenous levels of the neurosteroid 3 alpha,5 alpha-THP.
Topics: Animals; Brain; Brain Chemistry; Corpus Luteum; Endocrine System; Estrus; Female; Finasteride; Injections, Subcutaneous; Isomerism; Kainic Acid; Postpartum Period; Pregnancy; Pregnanolone; Progesterone; Rats; Rats, Long-Evans; Seizures; Time Factors | 1998 |
Role of brain allopregnanolone in the plasticity of gamma-aminobutyric acid type A receptor in rat brain during pregnancy and after delivery.
Topics: Animals; Cell Membrane; Cerebral Cortex; Chlorides; Desoxycorticosterone; Estrus; Female; Finasteride; Gene Expression Regulation; Hippocampus; Muscimol; Postpartum Period; Pregnancy; Pregnancy, Animal; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger; Time Factors; Transcription, Genetic | 1998 |
Effect of pregnancy and steroid hormones on plasma adrenomedullin levels in the rat.
Topics: Adrenomedullin; Animals; Estradiol; Female; Peptides; Pregnancy; Pregnancy, Animal; Pregnanolone; Progesterone; Rats; Rats, Long-Evans | 1998 |
Pregnancy-induced changes in central response to atrial distension mimicked by progesterone metabolite.
Topics: Animals; Atrial Function; Female; Neurons; Paraventricular Hypothalamic Nucleus; Pregnancy; Pregnancy, Animal; Pregnanolone; Progesterone; Proto-Oncogene Proteins c-fos; Rats; Rats, Long-Evans | 1998 |
Changes in properties and neurosteroid regulation of GABAergic synapses in the supraoptic nucleus during the mammalian female reproductive cycle.
Topics: Actins; Animals; Excitatory Postsynaptic Potentials; Female; GABA Modulators; gamma-Aminobutyric Acid; In Vitro Techniques; Labor, Obstetric; Lactation; Neurotransmitter Agents; Oxytocin; Patch-Clamp Techniques; Pregnancy; Pregnanolone; Rats; Receptors, GABA-A; Reproduction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Supraoptic Nucleus; Synapses | 1999 |
Effects of pregnanolone on behavioural parameters and the responses to GABA(A) receptor antagonists in the late gestation fetal sheep.
Topics: Animals; Bicuculline; Electroencephalography; Electromyography; Electrooculography; Embryonic and Fetal Development; Female; GABA Antagonists; Gestational Age; Picrotoxin; Pregnancy; Pregnanolone; Receptors, GABA-A; Respiration; Sheep | 1999 |
Prenatal stress reduces the effectiveness of the neurosteroid 3 alpha,5 alpha-THP to block kainic-acid-induced seizures.
Topics: Analysis of Variance; Animals; Anticonvulsants; Corticosterone; Female; gamma-Aminobutyric Acid; Hippocampus; Immobilization; Kainic Acid; Male; Maze Learning; Pregnancy; Pregnanolone; Prenatal Exposure Delayed Effects; Radioimmunoassay; Rats; Rats, Long-Evans; Seizures; Sex Characteristics; Stress, Psychological | 1999 |
Patterns of urinary and fecal steroid excretion during the ovarian cycle and pregnancy in the African elephant (Loxodonta africana).
Topics: 5-alpha-Dihydroprogesterone; Animals; Chromatography, High Pressure Liquid; Elephants; Estradiol; Estrone; Estrus; Feces; Female; Gestational Age; Immunoenzyme Techniques; Pregnancy; Pregnancy, Animal; Pregnanediones; Pregnanolone; Progesterone; Steroids | 1999 |
Changes in GABAA receptor-mediated synaptic transmission in oxytocin neurons during female reproduction: plasticity in a neuroendocrine context.
Topics: Animals; Female; Neurons; Oxytocin; Patch-Clamp Techniques; Pregnancy; Pregnanolone; Rats; Receptors, GABA-A; Supraoptic Nucleus | 1999 |
Physiological modulation of GABA(A) receptor plasticity by progesterone metabolites.
Topics: Animals; Binding Sites; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Convulsants; Drug Interactions; Enzyme Inhibitors; Estrus; Female; Finasteride; Flunitrazepam; GABA Modulators; Gestational Age; Hippocampus; Postpartum Period; Pregnancy; Pregnancy, Animal; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 1999 |
Mating stimuli influence endogenous variations in the neurosteroids 3alpha,5alpha-THP and 3alpha-Diol.
Topics: Androgens; Androstane-3,17-diol; Animals; Brain; Corticosterone; Estrogens; Estrus; Female; Male; Organ Specificity; Physical Stimulation; Postpartum Period; Posture; Pregnancy; Pregnanolone; Rats; Rats, Long-Evans; Sexual Behavior, Animal; Touch | 1999 |
Progesterone-metabolite prevents protein kinase C-dependent modulation of gamma-aminobutyric acid type A receptors in oxytocin neurons.
Topics: Allosteric Regulation; Animals; Female; GABA-A Receptor Agonists; Hypothalamus; Male; Neurons; Oxytocin; Pregnancy; Pregnanolone; Progesterone; Protein Kinase C; Rats; Rats, Wistar; Receptors, GABA-A; Signal Transduction | 2000 |
In vivo evidences of early neurosteroid synthesis in the developing rat central nervous system and placenta.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Carbon Radioisotopes; Central Nervous System; Chromatography, Thin Layer; Female; Male; Placenta; Pregnancy; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley | 2000 |
Effect of a neuroactive steroid infused into the cerebral ventricles of fetal sheep in utero using small infusion volumes.
Topics: Animals; Behavior, Animal; Electroencephalography; Electromyography; Electrooculography; Female; Fetal Movement; Fetus; Injections, Intraventricular; Pregnancy; Pregnanolone; Sheep; Sleep; Wakefulness | 2000 |
Characterisation of GABA(A) receptors in fetal, neonatal and adult ovine brain: region and age related changes and the effects of allopregnanolone.
Topics: Aging; Animals; Animals, Newborn; Binding, Competitive; Brain; Brain Stem; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Female; Fetus; Frontal Lobe; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Male; Picrotoxin; Pregnancy; Pregnanolone; Receptors, GABA-A; Sheep; Sulfur Radioisotopes | 2000 |
Localization of p450scc and 5alpha-reductase type-2 in the cerebellum of fetal and newborn sheep.
Topics: Animals; Animals, Newborn; Cerebellum; Cholestenone 5 alpha-Reductase; Cholesterol Side-Chain Cleavage Enzyme; Female; Fluorescent Antibody Technique, Indirect; Oxidoreductases; Pregnancy; Pregnanolone; Purkinje Cells; Receptors, GABA-A; Sheep | 2000 |
Determination of progesterone and some of its neuroactive ring A-reduced metabolites in human serum.
Topics: Adolescent; Adult; Antibody Specificity; Binding, Competitive; Chromatography, High Pressure Liquid; Cross Reactions; Female; Humans; Immune Sera; Male; Menstrual Cycle; Middle Aged; Pregnancy; Pregnanediones; Pregnanolone; Progesterone; Radioimmunoassay; Reference Standards; Solvents | 2000 |
Allopregnanolone assays.
Topics: Chromatography, High Pressure Liquid; Female; Humans; Pregnancy; Pregnanolone; Radioimmunoassay; Sensitivity and Specificity | 2001 |
Neuroactive steroids, their precursors, and polar conjugates during parturition and postpartum in maternal and umbilical blood: 1. Identification and simultaneous determination of pregnanolone isomers.
Topics: Adult; Female; Fetal Blood; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Labor, Obstetric; Postpartum Period; Pregnancy; Pregnanolone; Stereoisomerism | 2000 |
Diethylstilbestrol regulates trophoblast stem cell differentiation as a ligand of orphan nuclear receptor ERR beta.
Topics: Animals; Cell Differentiation; Chlorocebus aethiops; COS Cells; Diethylstilbestrol; ERRalpha Estrogen-Related Receptor; Estradiol; Estrogens, Non-Steroidal; Etiocholanolone; Female; Fibroblast Growth Factors; Fluorometry; Genes, Reporter; Gestational Age; Giant Cells; Ligands; Luciferases; Mice; Molecular Structure; Nuclear Receptor Coactivator 2; Placenta; Pregnancy; Pregnanolone; Receptors, Cytoplasmic and Nuclear; Receptors, Estrogen; Recombinant Fusion Proteins; Stem Cells; Transcription Factors; Transcriptional Activation; Transfection; Trophoblasts | 2001 |
Regulation of uterine gamma-aminobutyric acid(A) receptor subunit expression throughout pregnancy.
Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; Animals; Female; Gene Expression Regulation, Developmental; Muscimol; Pregnancy; Pregnancy, Animal; Pregnanolone; Protein Subunits; Rats; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Uterus | 2001 |
Neuroactive steroids, their precursors and polar conjugates during parturition and postpartum in maternal blood: 2. Time profiles of pregnanolone isomers.
Topics: Adult; Analgesics; Female; Gas Chromatography-Mass Spectrometry; Humans; Labor, Obstetric; Postpartum Period; Pregnancy; Pregnanolone; Stereoisomerism; Steroids; Time Factors | 2001 |
Antiprogestagen activity of 5H-progesterone metabolites and their analogues, 16alpha,17alpha-cyclohexane-5H-pregnan-3,20-diones.
Topics: Abortifacient Agents, Steroidal; Animals; Female; Mifepristone; Molecular Structure; Pregnancy; Pregnancy Maintenance; Pregnancy, Animal; Pregnanolone; Progesterone; Progestins; Rats | 2001 |
Early postnatal ethanol intubation blunts GABA(A) receptor up-regulation and modifies 3alpha-hydroxy-5alpha-pregnan-20-one sensitivity in rat MS/DB neurons.
Topics: Age Factors; Allosteric Regulation; Animals; Animals, Suckling; Anticonvulsants; Central Nervous System Depressants; Dose-Response Relationship, Drug; Drug Resistance; Ethanol; Female; Intubation, Gastrointestinal; Male; Neurons; Patch-Clamp Techniques; Pregnancy; Pregnanolone; Prosencephalon; Rats; Receptors, GABA-A; Up-Regulation; Zinc | 2001 |
3Alpha-hydroxy-5alpha-pregnan-20-one levels and GABA(A) receptor-mediated 36Cl(-) flux across development in rat cerebral cortex.
Topics: Allosteric Regulation; Animals; Animals, Newborn; Anti-Anxiety Agents; Biological Transport; Cerebral Cortex; Chlorine; Desoxycorticosterone; Female; Flunitrazepam; GABA Agonists; GABA Modulators; Labor, Obstetric; Male; Muscimol; Pregnancy; Pregnanolone; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sex Characteristics | 2001 |
Two neuroactive steroids in midpregnancy as measured in maternal and fetal sera and in amniotic fluid.
Topics: Amniotic Fluid; Female; Fetal Blood; Gonadal Steroid Hormones; History, 16th Century; Humans; Pregnancy; Pregnancy Trimester, Second; Pregnanolone; Pregnenolone; Sensitivity and Specificity | 2002 |
Neonatal isolation alters stress hormone and mesolimbic dopamine release in juvenile rats.
Topics: Age Factors; Animals; Animals, Newborn; Corticosterone; Dopamine; Female; Handling, Psychological; Limbic System; Male; Nucleus Accumbens; Pregnancy; Pregnanolone; Rats; Rats, Sprague-Dawley; Social Isolation; Stress, Physiological | 2002 |
Initiation of human parturition. VI. Identification and quantification of progesterone metabolites produced by the components of human fetal membranes.
Topics: 20-alpha-Dihydroprogesterone; Amnion; Chorion; Chromatography; Extraembryonic Membranes; Female; Humans; Labor Onset; Labor, Obstetric; NADP; Pregnancy; Pregnanediones; Pregnanolone; Progesterone | 1977 |
Initiation of human parturition. IX. Progesterone metabolism by placentas of early and late human gestation.
Topics: 20-alpha-Dihydroprogesterone; 20-Hydroxysteroid Dehydrogenases; Female; Gestational Age; Humans; NADP; Placenta; Pregnancy; Pregnanediones; Pregnanolone; Progesterone | 1978 |
Compounds in the urinary pH 1 extract reacting with corticosteroid and tetrahydrocorticosteroid antisera. Separation of a nonpolar substance with affinity to a tetrahydroaldosterone antiserum.
Topics: Adrenal Cortex Hormones; Aldosterone; Antibodies; Cortisone; Cortodoxone; Desoxycorticosterone; Female; Glucuronates; Humans; Hydrogen-Ion Concentration; Pregnancy; Pregnanolone; Radioimmunoassay; Tetrahydrocortisol | 1978 |
5 alpha-Reductase activity in human placenta.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Carbon Radioisotopes; Culture Media; Female; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Isotope Labeling; NADP; Oxidoreductases; Placenta; Pregnancy; Pregnanediones; Pregnanolone; Progesterone; Tritium | 1979 |
Effects of gonadal steroids on output of luteinizing hormone releasing factor into pituitary stalk blood in the female rat.
Topics: Adrenalectomy; Animals; Castration; Estradiol; Female; Gonadotropin-Releasing Hormone; Light; Periodicity; Pituitary Gland; Pregnancy; Pregnanolone; Proestrus; Progesterone; Rats; Secretory Rate; Tamoxifen | 1979 |
Serum levels of progesterone, 5 alpha-dihydroprogesterone and hydroxy-5 alpha-pregnanones in the prepartum and postpartum equine.
Topics: 20-alpha-Dihydroprogesterone; Animals; Female; Horses; Isomerism; Labor Onset; Labor, Obstetric; Pregnancy; Pregnancy, Animal; Pregnanes; Pregnanolone; Progesterone; Time Factors | 1979 |
Metabolism of progesterone in the pregnant sheep near term: identification of 3 beta-hydroxy-5 alpha-pregnan-20-one 3-sulfate as a major metabolite.
Topics: Animals; Carbon Radioisotopes; Female; Isotope Labeling; Pregnancy; Pregnancy, Animal; Pregnanes; Pregnanolone; Progesterone; Sheep; Tritium | 1979 |
Some aspects of oocyte maturation in catfish.
Topics: Animals; Estradiol; Female; Fishes; Gonadotropins; Hydrocortisone; Interrenal Gland; Luteinizing Hormone; Oocytes; Ovary; Ovum; Pregnancy; Pregnanolone; Testosterone | 1979 |
Pregnanolones and pregnenolone in human myometrium at term of pregnancy.
Topics: Chromatography, Gas; Chromatography, Gel; Female; Humans; Myometrium; Pregnancy; Pregnancy Trimester, Third; Pregnanes; Pregnanolone; Pregnenolone; Stereoisomerism; Uterus | 1979 |
Pregnanolones, pregnenolone and progesterone in the human feto-placental circulation at term of pregnancy.
Topics: Chromatography, Gas; Female; Fetal Blood; Humans; Hydroxysteroids; Maternal-Fetal Exchange; Placenta; Pregnancy; Pregnancy Trimester, Third; Pregnanes; Pregnanolone; Pregnenolone; Progesterone | 1979 |
Pregnanolones, pregnenolone and progesterone in the human fetal tissues of early and midtrimester pregnancy.
Topics: Female; Fetus; Humans; Hydroxysteroids; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Second; Pregnanes; Pregnanolone; Pregnenolone; Progesterone; Tissue Distribution | 1979 |
Circulating plasma levels of pregnenolone, progesterone, estrogen, luteinizing hormone, and follicle stimulating hormone in young and aged C57BL/6 mice during various stages of pregnancy.
Topics: Aging; Animals; Embryo Implantation; Estrogens; Female; Follicle Stimulating Hormone; Gonadotropins; Humans; Litter Size; Luteinizing Hormone; Maternal Age; Mice; Mice, Inbred C57BL; Pregnancy; Pregnancy, Animal; Pregnanolone; Steroids; Time Factors | 1978 |
In vitro inhibition of rat uterine contractility induced by 5 alpha and 5 beta progestins.
Topics: 20-alpha-Dihydroprogesterone; Animals; Diestrus; Dose-Response Relationship, Drug; Female; Isomerism; Pregnancy; Pregnanediol; Pregnanediones; Pregnanes; Pregnanolone; Progesterone; Progestins; Rats; Stereoisomerism; Structure-Activity Relationship; Uterine Contraction | 1979 |
Initiation of human parturition. VIII. Metabolism of progesterone by fetal membranes of early and late human gestation.
Topics: Extraembryonic Membranes; Female; Gestational Age; Humans; Labor Onset; Pregnancy; Pregnanediol; Pregnanolone; Pregnenolone; Progesterone | 1977 |
Steroid profiles in hydatidiform mole associated with theca-lutein cysts.
Topics: Adult; Chorionic Gonadotropin; Female; Humans; Hydatidiform Mole; Ovarian Cysts; Pregnancy; Pregnanediol; Pregnanes; Pregnanetriol; Pregnanolone; Theca Cells; Ultrasonography; Uterine Neoplasms; Vacuum Curettage | 1977 |
Corticosteroid production by the human foetus: evidence from analysis of urine from women pregnant with a normal or an anencephalic foetus.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Anencephaly; Female; Fetus; Humans; Pregnancy; Pregnanetriol; Pregnanolone | 1976 |
Physiological variations in the ovarian production of 5alpha-pregnane derivatives with sedative properties in the rat.
Topics: Anesthetics; Animals; Estrus; Female; Ovary; Pregnancy; Pregnanediol; Pregnanes; Pregnanolone; Progesterone; Rats | 1975 |
Origin of 5alpha-pregnane-3alpha,20alpha,21-triol 3-sulphate in pregnant women.
Topics: Female; Humans; Pregnancy; Pregnancy Trimester, Third; Pregnanetriol; Pregnanolone; Sulfates | 1975 |
Metabolism of progesterone by rat ovarian tissue: influence of pregnant mare serum gonadotropin and prolactin.
Topics: Androstane-3,17-diol; Androstenedione; Androsterone; Animals; Chromatography, Thin Layer; Estrus; Female; Gonadotropins, Equine; Isomerism; Ovarian Follicle; Ovary; Ovulation; Pregnancy; Pregnanolone; Progesterone; Prolactin; Rats; Testosterone; Theca Cells | 1975 |
Conversion of pregnenolone to progesterone by mouse morulae and blastocysts.
Topics: 5-alpha-Dihydroprogesterone; Animals; Blastocyst; Cleavage Stage, Ovum; Female; Mice; Mice, Inbred Strains; Morula; Pregnancy; Pregnanediones; Pregnanolone; Pregnenolone; Progesterone | 1990 |
Stable isotope studies on steroid metabolism and kinetics: sulfates of 3 alpha-hydroxy-5 alpha-pregnane derivatives in human pregnancy.
Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Deuterium; Female; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Hydroxylation; Kinetics; Oxidation-Reduction; Pregnancy; Pregnanediol; Pregnanolone; Steroid 16-alpha-Hydroxylase; Sulfates | 1990 |
Pregnancy-induced alterations of GABAA receptor sensitivity in maternal brain: an antecedent of post-partum 'blues'?
Topics: Animals; Female; Frontal Lobe; Gestational Age; Muscimol; Postpartum Period; Pregnancy; Pregnancy, Animal; Pregnanolone; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1989 |
Modulation of uterine GABAA receptors during gestation and by tetrahydroprogesterone.
Topics: Animals; Female; Kinetics; Muscimol; Pregnancy; Pregnancy, Animal; Pregnanes; Pregnanolone; Rats; Rats, Inbred Strains; Receptors, GABA-A; Uterus | 1989 |
Identification of 20 alpha-hydroxy-5 alpha-pregnan-3-one and 20 beta-hydroxy-5 alpha-pregnan-3-one in human pregnancy urine.
Topics: Chromatography, High Pressure Liquid; Female; Gas Chromatography-Mass Spectrometry; Humans; Pregnancy; Pregnanes; Pregnanolone; Reference Values | 1989 |
Abnormal steroid excretion in gestational trophoblastic disease complicated by ovarian theca-lutein cysts.
Topics: Adult; Chromatography, Gas; Female; Humans; Male; Ovarian Cysts; Pregnancy; Pregnanediol; Pregnanetriol; Pregnanolone; Steroids; Trophoblastic Neoplasms; Uterine Neoplasms | 1986 |
Determination of ovulation and pregnancy in the marmoset (Callithrix jacchus) by monitoring of urinary hydroxypregnanolone excretion.
Topics: Animals; Callithrix; Callitrichinae; Chromatography, High Pressure Liquid; Female; Ovulation Detection; Pregnancy; Pregnancy, Animal; Pregnanes; Pregnanolone; Reference Values | 1987 |
Identification of the main gestagen metabolite in marmoset (Callithrix jacchus) urine by NMR and MS spectroscopy.
Topics: Animals; Callithrix; Callitrichinae; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Female; Hydrolysis; Magnetic Resonance Spectroscopy; Mass Spectrometry; Pregnancy; Pregnanes; Pregnanolone | 1988 |
Embryotoxic effects of thalidomide derivatives in the non-human primate Callithrix jacchus. II. Elucidation of the susceptible period and of the variability of embryonic stages.
Topics: Animals; Callithrix; Embryo, Mammalian; Embryonic and Fetal Development; Female; Gestational Age; Male; Ovulation; Pregnancy; Pregnanolone; Species Specificity; Thalidomide | 1988 |
Metabolism of progesterone by hamster blastocysts and the ontogeny of progesterone metabolic capability.
Topics: 5-alpha-Dihydroprogesterone; Animals; Blastocyst; Cricetinae; Female; Mesocricetus; Pregnancy; Pregnanediones; Pregnanolone; Progesterone | 1985 |