pregnanolone has been researched along with Niemann-Pick Disease in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gong, W; Griffin, LD; Mellon, SH; Verot, L | 1 |
| Burns, MP; Duff, K | 1 |
| Gong, W; Griffin, LD; Mellon, S | 1 |
| Ahmad, I; Bi, X; Chaitkin, E; Erickson, RP; Hicks, C; Howison, CM; Lope-Piedrafita, S; Trouard, TP; Weberg, L; Yao, Y; Yu, C | 1 |
| Covey, DF; Frolov, A; Gale, SE; Langmade, SJ; Mellon, SH; Mohri, I; Ory, DS; Schaffer, JE; Suzuki, K; Walkley, SU | 1 |
| Dietschy, JM; Li, H; Liu, B; Repa, JJ; Turley, SD | 1 |
6 other study(ies) available for pregnanolone and Niemann-Pick Disease
| Article | Year |
|---|---|
Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone.
Topics: 20-alpha-Hydroxysteroid Dehydrogenase; 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); Animals; Brain; Mice; Niemann-Pick Diseases; Pregnanolone; Pregnenolone; Rats | 2004 |
Brain on steroids resists neurodegeneration.
Topics: Animals; Brain; Cell Death; Mice; Neurons; Niemann-Pick Diseases; Pregnanolone | 2004 |
Niemann pick type C disease as a model for defects in neurosteroidogenesis.
Topics: Animals; Brain; Embryo, Mammalian; Mice; Mice, Knockout; Mice, Mutant Strains; Nervous System; Neurotransmitter Agents; Niemann-Pick Diseases; Phenotype; Pregnanolone; Steroid 17-alpha-Hydroxylase; Tissue Distribution | 2004 |
Allopregnanolone treatment, both as a single injection or repetitively, delays demyelination and enhances survival of Niemann-Pick C mice.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Age Factors; Anesthetics; Animals; Anisotropy; Antigens, Differentiation; Body Weight; Brain; Cell Count; Cell Survival; Demyelinating Diseases; Disease Models, Animal; Drug Administration Schedule; Glial Fibrillary Acidic Protein; Immunohistochemistry; Magnetic Resonance Imaging; Membrane Transport Proteins; Mice; Mice, Inbred BALB C; Mice, Knockout; Motor Activity; Niemann-Pick Diseases; Pregnanolone; Time Factors | 2005 |
Pregnane X receptor (PXR) activation: a mechanism for neuroprotection in a mouse model of Niemann-Pick C disease.
Topics: Animals; Cerebellum; Disease Models, Animal; GABA-A Receptor Agonists; Gene Expression; Hydrocarbons, Fluorinated; Intracellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Microglia; Mutation; Neuroprotective Agents; Niemann-Pick C1 Protein; Niemann-Pick Diseases; Pregnane X Receptor; Pregnanolone; Proteins; Purkinje Cells; Receptors, Steroid; Stereoisomerism; Sulfonamides | 2006 |
Genetic variations and treatments that affect the lifespan of the NPC1 mouse.
Topics: Animals; Cyclodextrins; DNA-Binding Proteins; Gene Deletion; Genetic Variation; Intracellular Signaling Peptides and Proteins; Liver X Receptors; Longevity; Mice; Mice, Knockout; Neurodegenerative Diseases; Niemann-Pick C1 Protein; Niemann-Pick Diseases; Orphan Nuclear Receptors; Pregnanolone; Proteins; Receptors, Cytoplasmic and Nuclear; Sialyltransferases; Treatment Outcome | 2008 |