Page last updated: 2024-08-23

pregnanolone and Neurovisceral Storage Disease with Vertical Supranuclear Ophthalmoplegia

pregnanolone has been researched along with Neurovisceral Storage Disease with Vertical Supranuclear Ophthalmoplegia in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (41.67)29.6817
2010's6 (50.00)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Antipova, V; Holzmann, C; Rolfs, A; Witt, M; Wree, A1
Günther, R; Holzmann, C; Meyer, A; Rolfs, A; Schmitt, O; Witt, M; Wree, A1
Bräuer, AU; Burstein, C; Engelmann, R; Frank, M; Gläser, A; Gräler, M; Müller-Hilke, B; Neidhardt, J; Neßlauer, AM; Rolfs, A; Witt, M; Wree, A1
Frech, MJ; Holzmann, C; Hovakimyan, M; Hübner, R; Lukas, J; Maass, F; Petersen, J; Rolfs, A; Witt, M; Wree, A1
Hawlitschka, A; Hovakimyan, M; Lukas, J; Maass, F; Petersen, J; Rolfs, A; Schmitt, O; Witt, M; Wree, A1
Grittner, U; Holzmann, C; Rolfs, A; Schlegel, V; Thieme, M; Witt, M; Wree, A1
Erickson, RP; Hicks, CM; Lope-Piedrafita, S; Totenhagen, JW; Trouard, TP1
Bembi, B; Butters, TD; Covey, DF; Dardis, A; Mellon, SH; Nevyjel, M; Zampieri, S1
Bi, X; Cheung, S; Galeano, J; Ji, AX; Liao, G; Qin, Q1
Ali, NF; Davidson, CD; Dobrenis, K; Micsenyi, MC; Ory, DS; Renault, S; Stephney, G; Vanier, MT; Walkley, SU1
Guthoff, R; Hovakimyan, M; Lukas, J; Maass, F; Petersen, J; Reichard, M; Rolfs, A; Stachs, O; Witt, M; Wree, A1
Gong, W; Mellon, SH; Schonemann, MD1

Reviews

1 review(s) available for pregnanolone and Neurovisceral Storage Disease with Vertical Supranuclear Ophthalmoplegia

ArticleYear
Endogenous and synthetic neurosteroids in treatment of Niemann-Pick Type C disease.
    Brain research reviews, 2008, Volume: 57, Issue:2

    Topics: Animals; Disease Models, Animal; Gonadal Steroid Hormones; Humans; Mice; Niemann-Pick Disease, Type C; Pregnanolone; Receptors, GABA-A

2008

Other Studies

11 other study(ies) available for pregnanolone and Neurovisceral Storage Disease with Vertical Supranuclear Ophthalmoplegia

ArticleYear
Gender-Specific Effects of Two Treatment Strategies in a Mouse Model of Niemann-Pick Disease Type C1.
    International journal of molecular sciences, 2021, Mar-03, Volume: 22, Issue:5

    Topics: 1-Deoxynojirimycin; 2-Hydroxypropyl-beta-cyclodextrin; Animals; Cyclodextrins; Disease Models, Animal; Drug Therapy, Combination; Female; Male; Mice; Mice, Inbred BALB C; Niemann-Pick Disease, Type C; Pregnanolone

2021
Increased Regenerative Capacity of the Olfactory Epithelium in Niemann-Pick Disease Type C1.
    International journal of molecular sciences, 2017, Apr-06, Volume: 18, Issue:4

    Topics: 1-Deoxynojirimycin; 2-Hydroxypropyl-beta-cyclodextrin; Animals; Apoptosis; beta-Cyclodextrins; Cell Proliferation; Disease Models, Animal; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mutation; Niemann-Pick C1 Protein; Niemann-Pick Disease, Type C; Olfactory Mucosa; Pregnanolone; Proteins

2017
A therapy with miglustat, 2-hydroxypropyl-ß-cyclodextrin and allopregnanolone restores splenic cholesterol homeostasis in Niemann-pick disease type C1.
    Lipids in health and disease, 2019, Jun-28, Volume: 18, Issue:1

    Topics: 1-Deoxynojirimycin; 2-Hydroxypropyl-beta-cyclodextrin; Animals; Cell Separation; Disease Models, Animal; Flow Cytometry; Genotype; Lipid Metabolism; Mice; Niemann-Pick Disease, Type C; Pregnanolone; Spleen

2019
Combined therapy with cyclodextrin/allopregnanolone and miglustat improves motor but not cognitive functions in Niemann-Pick Type C1 mice.
    Neuroscience, 2013, Nov-12, Volume: 252

    Topics: 1-Deoxynojirimycin; Animals; Cognition; Cyclodextrins; Disease Models, Animal; Drug Therapy, Combination; Mice; Mice, Knockout; Microscopy, Electron, Transmission; Motor Activity; Neuroprotective Agents; Niemann-Pick Disease, Type C; Pregnanolone

2013
Reduced cerebellar neurodegeneration after combined therapy with cyclodextrin/allopregnanolone and miglustat in NPC1: a mouse model of Niemann-Pick type C1 disease.
    Journal of neuroscience research, 2015, Volume: 93, Issue:3

    Topics: 1-Deoxynojirimycin; Animals; Cell Count; Cerebellum; Cyclodextrins; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Enzyme Inhibitors; Mice; Nerve Degeneration; Neurons; Niemann-Pick Disease, Type C; Pregnanolone

2015
Pharmacologic Treatment Assigned for Niemann Pick Type C1 Disease Partly Changes Behavioral Traits in Wild-Type Mice.
    International journal of molecular sciences, 2016, Nov-09, Volume: 17, Issue:11

    Topics: 1-Deoxynojirimycin; Animals; Behavior, Animal; Body Weight; Brain; Cognition; Cyclodextrins; Disease Models, Animal; Drug Administration Schedule; Drug Combinations; Hypolipidemic Agents; Male; Maze Learning; Mice; Mice, Inbred BALB C; Niemann-Pick Disease, Type C; Organ Size; Pregnanolone

2016
MRI detects therapeutic effects in weanling Niemann-Pick type C mice.
    Journal of neuroscience research, 2008, Volume: 86, Issue:12

    Topics: Animals; Animals, Newborn; Brain; Diffusion Magnetic Resonance Imaging; Intracellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Mice, Transgenic; Niemann-Pick C1 Protein; Niemann-Pick Disease, Type C; Pregnanolone; Proteins; Weaning

2008
Oxidative stress in NPC1 deficient cells: protective effect of allopregnanolone.
    Journal of cellular and molecular medicine, 2009, Volume: 13, Issue:9B

    Topics: Apoptosis; Biopsy; Carrier Proteins; Cell Line, Tumor; Child, Preschool; Cholesterol; Female; Fibroblasts; Humans; Intracellular Signaling Peptides and Proteins; Lipid Peroxidation; Lysosomes; Male; Membrane Glycoproteins; Niemann-Pick C1 Protein; Niemann-Pick Disease, Type C; Oxidation-Reduction; Oxidative Stress; Pregnanolone

2009
Allopregnanolone treatment delays cholesterol accumulation and reduces autophagic/lysosomal dysfunction and inflammation in Npc1-/- mouse brain.
    Brain research, 2009, May-13, Volume: 1270

    Topics: Anesthetics; Animals; Astrocytes; Autophagy; Cholesterol; Disease Models, Animal; Encephalitis; Intracellular Signaling Peptides and Proteins; Lysosomes; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Microglia; Myelin Sheath; Neurons; Niemann-Pick C1 Protein; Niemann-Pick Disease, Type C; Pregnanolone; Proteins

2009
Chronic cyclodextrin treatment of murine Niemann-Pick C disease ameliorates neuronal cholesterol and glycosphingolipid storage and disease progression.
    PloS one, 2009, Sep-11, Volume: 4, Issue:9

    Topics: 1-Deoxynojirimycin; 2-Hydroxypropyl-beta-cyclodextrin; Animals; beta-Cyclodextrins; Cholesterol; Cyclodextrins; Disease Models, Animal; Disease Progression; Drug Synergism; Enzyme Inhibitors; Glycosphingolipids; Mice; Mice, Transgenic; Neurons; Niemann-Pick Disease, Type C; Pregnanolone; Treatment Outcome

2009
Corneal alterations during combined therapy with cyclodextrin/allopregnanolone and miglustat in a knock-out mouse model of NPC1 disease.
    PloS one, 2011, Volume: 6, Issue:12

    Topics: 1-Deoxynojirimycin; Anesthetics; Animals; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cornea; Cyclodextrins; Disease Progression; Drug Therapy, Combination; Enzyme Inhibitors; Genotype; Intracellular Signaling Peptides and Proteins; Lysosomes; Mass Spectrometry; Mice; Mice, Knockout; Microscopy, Confocal; Models, Biological; Mutation; Niemann-Pick C1 Protein; Niemann-Pick Disease, Type C; Pregnanolone; Proteins

2011