Page last updated: 2024-08-23

pregnanolone and Mood Disorders

pregnanolone has been researched along with Mood Disorders in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (50.00)29.6817
2010's7 (43.75)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Pinna, G1
Burke, CS; Hermann, AD; Susser, LC1
Mody, I1
Bäckström, T; Bixo, M; Johansson, M; Nyberg, S; Ossewaarde, L; Ragagnin, G; Savic, I; Strömberg, J; Timby, E; van Broekhoven, F; van Wingen, G1
Rubinow, DR; Schiller, CE; Schmidt, PJ1
Bičíková, M; Dušková, M; Hill, M; Mohr, P; Řípová, D; Šrámková, M; Stárka, L1
Costa, E; Guidotti, A; Pinna, G1
Brunelli, SA; Killien, EY; Martinez, AR; Robinson, SA; Skudder, CM; Zimmerberg, B1
Johansson, AG; Landén, M; Nikamo, P; Schalling, M1
Andersson, A; Andreé, L; Bäckström, T; Birzniece, V; Bixo, M; Björn, I; Haage, D; Isaksson, M; Johansson, IM; Lindblad, C; Lundgren, P; Nyberg, S; Odmark, IS; Strömberg, J; Sundström-Poromaa, I; Turkmen, S; Wahlström, G; Wang, M; Wihlbäck, AC; Zhu, D; Zingmark, E1
Fisch, B; Galdor, M; Kaplan, B; Kinor, N; Maayan, R; Shinnar, N; Valevski, A; Weizman, A; Zeldich, E1
Bäckström, T; Bixo, M; Nyberg, S; Sundström-Poromaa, I; Wihlbäck, AC1
Andersson, A; Andréen, L; Bäckström, T; Bixo, M; Nyberg, S; Sundström-Poromaa, I1
Begliuomini, S; Bernardi, F; Genazzani, AR; Lenzi, E; Luisi, M; Palumbo, M; Pluchino, N1
Aszalós, Z1
Girdler, SS; Light, KC; Morrow, AL; Pedersen, CA; Straneva, PA1

Reviews

7 review(s) available for pregnanolone and Mood Disorders

ArticleYear
GABA
    Archives of women's mental health, 2019, Volume: 22, Issue:1

    Topics: Depression; Depression, Postpartum; Female; Humans; Menstruation; Mood Disorders; Postpartum Period; Pregnanolone; Receptors, GABA; Weaning

2019
Allopregnanolone and mood disorders.
    Progress in neurobiology, 2014, Volume: 113

    Topics: Animals; Brain; Female; Humans; Mood Disorders; Pregnanolone; Receptors, GABA-A

2014
Allopregnanolone as a mediator of affective switching in reproductive mood disorders.
    Psychopharmacology, 2014, Volume: 231, Issue:17

    Topics: Adult; Affect; Depression, Postpartum; Female; Humans; Mood Disorders; Neurotransmitter Agents; Pregnancy; Pregnanolone; Premenstrual Syndrome

2014
SSRIs act as selective brain steroidogenic stimulants (SBSSs) at low doses that are inactive on 5-HT reuptake.
    Current opinion in pharmacology, 2009, Volume: 9, Issue:1

    Topics: Animals; Brain; Fluoxetine; gamma-Aminobutyric Acid; Humans; Mental Disorders; Mood Disorders; Pregnanolone; Receptors, GABA-A; Selective Serotonin Reuptake Inhibitors; Social Isolation; Synaptic Transmission

2009
Pathogenesis in menstrual cycle-linked CNS disorders.
    Annals of the New York Academy of Sciences, 2003, Volume: 1007

    Topics: Affect; Animals; Female; Humans; Menstrual Cycle; Mood Disorders; Pregnanolone; Premenstrual Syndrome; Receptors, GABA-A

2003
Disadaptive disorders in women: allopregnanolone, a sensitive steroid.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2004, Volume: 19, Issue:6

    Topics: Affect; Amenorrhea; Animals; Anxiety; Behavior; Depression; Female; Humans; Hypothalamus; Menopause; Mental Disorders; Mood Disorders; Pregnanolone; Premenstrual Syndrome; Puerperal Disorders; Stress, Physiological

2004
[Neurological and psychiatric aspects of some endocrine diseases. The role of neurosteroids and neuroactive steroids].
    Orvosi hetilap, 2007, Oct-14, Volume: 148, Issue:41

    Topics: Addison Disease; Adrenal Cortex Hormones; Androgens; Anxiety; Cognition Disorders; Cushing Syndrome; Depression; Endocrine System Diseases; Estrogens; Fear; Fetal Organ Maturity; Gonadal Steroid Hormones; Humans; Memory Disorders; Mental Disorders; Mood Disorders; Muscle Weakness; Nervous System Diseases; Pain; Pregnanolone; Progesterone

2007

Trials

2 trial(s) available for pregnanolone and Mood Disorders

ArticleYear
Estradiol and the addition of progesterone increase the sensitivity to a neurosteroid in postmenopausal women.
    Psychoneuroendocrinology, 2005, Volume: 30, Issue:1

    Topics: Adult; Climacteric; Cross-Over Studies; Double-Blind Method; Electrooculography; Estradiol; Estrogen Replacement Therapy; Eye Movements; Female; Gonadal Steroid Hormones; Humans; Middle Aged; Mood Disorders; Pregnanolone; Progesterone; Saccades; Sleep Stages; Time Factors

2005
Relationship between allopregnanolone and negative mood in postmenopausal women taking sequential hormone replacement therapy with vaginal progesterone.
    Psychoneuroendocrinology, 2005, Volume: 30, Issue:2

    Topics: Administration, Intravaginal; Adult; Affect; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Estradiol; Female; Hormone Replacement Therapy; Humans; Middle Aged; Mood Disorders; Postmenopause; Pregnanolone; Progesterone; Severity of Illness Index

2005

Other Studies

7 other study(ies) available for pregnanolone and Mood Disorders

ArticleYear
Allopregnanolone, the Neuromodulator Turned Therapeutic Agent: Thank You, Next?
    Frontiers in endocrinology, 2020, Volume: 11

    Topics: Anesthetics; Humans; Mood Disorders; Neurotransmitter Agents; Pregnanolone; Prognosis

2020
GABA
    Cell, 2019, 01-10, Volume: 176, Issue:1-2

    Topics: Adult; beta-Cyclodextrins; Depression, Postpartum; Depressive Disorder, Major; Drug Combinations; Female; Humans; Mood Disorders; Neurotransmitter Agents; Postpartum Period; Pregnancy; Pregnanolone; Prevalence; Receptors, GABA-A

2019
The role of steroids in the prediction of affective disorders in adult men.
    Steroids, 2017, Volume: 121

    Topics: Adult; Anxiety; Dehydroepiandrosterone; Depression; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Mood Disorders; Multivariate Analysis; Pregnanolone; Radioimmunoassay; Steroids; Young Adult

2017
Effects of gestational allopregnanolone administration in rats bred for high affective behavior.
    Physiology & behavior, 2010, Feb-09, Volume: 99, Issue:2

    Topics: Analysis of Variance; Anesthetics; Animals; Animals, Newborn; Disease Models, Animal; Female; Male; Maternal Behavior; Maze Learning; Mood Disorders; Pregnancy; Pregnanolone; Prenatal Exposure Delayed Effects; Rats; Sexual Behavior, Animal; Swimming; Vocalization, Animal

2010
AKR1C4 gene variant associated with low euthymic serum progesterone and a history of mood irritability in males with bipolar disorder.
    Journal of affective disorders, 2011, Volume: 133, Issue:1-2

    Topics: Adult; Affect; Bipolar Disorder; Brain; Cyclothymic Disorder; Diagnostic and Statistical Manual of Mental Disorders; Female; Humans; Irritable Mood; Male; Middle Aged; Mood Disorders; Oxidoreductases; Point Mutation; Pregnanolone; Progesterone; Psychiatric Status Rating Scales

2011
Influence of 17beta-estradiol on the synthesis of reduced neurosteroids in the brain (in vivo) and in glioma cells (in vitro): possible relevance to mental disorders in women.
    Brain research, 2004, Sep-10, Volume: 1020, Issue:1-2

    Topics: 20-alpha-Dihydroprogesterone; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Analysis of Variance; Animals; Cerebral Cortex; Enzyme Inhibitors; Estradiol; Female; Glioma; Hormones; Humans; Hypothalamus; Mice; Mood Disorders; Neurons; Oxidation-Reduction; Pregnanolone; Progesterone; Rats; RNA, Messenger; Tumor Cells, Cultured

2004
Allopregnanolone levels and reactivity to mental stress in premenstrual dysphoric disorder.
    Biological psychiatry, 2001, May-01, Volume: 49, Issue:9

    Topics: Adult; Female; Follicular Phase; Humans; Hydrocortisone; Luteal Phase; Mood Disorders; Pregnanolone; Premenstrual Syndrome; Progesterone; Prospective Studies; Stress, Psychological

2001