pregnanolone has been researched along with Hepatic Encephalopathy in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Bäckström, T; Bixo, M; Das, R | 1 |
| Agusti, A; Bäckström, T; Doverskog, M; Felipo, V; Johansson, M; Llansola, M; Malinina, E; Montoliu, C; Ragagnin, G; Strömberg, J | 1 |
| Butterworth, RF | 1 |
| Ahboucha, S; Butterworth, RF; Layrargues, GP; Mamer, O | 1 |
| Ahboucha, S; Butterworth, RF; Coyne, L; Halliwell, RF; Hirakawa, R | 1 |
| Ahboucha, S; Butterworth, RF; Mamer, O; Pomier-Layrargues, G | 1 |
| Ahboucha, S; Butterworth, RF | 1 |
| Ahboucha, S; Baker, GB; Butterworth, RF; Chatauret, N; Jiang, W; Mamer, O | 1 |
3 review(s) available for pregnanolone and Hepatic Encephalopathy
| Article | Year |
|---|---|
Positive GABA
Topics: Animals; Anti-Anxiety Agents; Clinical Trials, Phase II as Topic; Female; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hepatic Encephalopathy; Humans; Pregnanolone; Premenstrual Dysphoric Disorder; Rats; Receptors, GABA-A | 2022 |
Neurosteroids in hepatic encephalopathy: Novel insights and new therapeutic opportunities.
Topics: Animals; Brain; Desoxycorticosterone; Drug Discovery; Hepatic Encephalopathy; Humans; Liver; Molecular Targeted Therapy; Neurotransmitter Agents; Pregnanolone; Receptors, GABA-A | 2016 |
The neurosteroid system: an emerging therapeutic target for hepatic encephalopathy.
Topics: Ammonia; Animals; Brain; Desoxycorticosterone; Hepatic Encephalopathy; Humans; Isoquinolines; Manganese; Pregnanolone; Receptors, GABA-A; Synaptic Transmission | 2007 |
5 other study(ies) available for pregnanolone and Hepatic Encephalopathy
| Article | Year |
|---|---|
GR3027 antagonizes GABAA receptor-potentiating neurosteroids and restores spatial learning and motor coordination in rats with chronic hyperammonemia and hepatic encephalopathy.
Topics: Animals; Circadian Rhythm; Desoxycorticosterone; Drug Antagonism; HEK293 Cells; Hepatic Encephalopathy; Humans; Hydroxysteroids; Hyperammonemia; Locomotion; Male; Maze Learning; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A | 2015 |
Increased brain concentrations of a neuroinhibitory steroid in human hepatic encephalopathy.
Topics: Brain Chemistry; Gas Chromatography-Mass Spectrometry; Hepatic Encephalopathy; Humans; Pregnanolone | 2005 |
An interaction between benzodiazepines and neuroactive steroids at GABA A receptors in cultured hippocampal neurons.
Topics: Affinity Labels; Allosteric Regulation; Animals; Azides; Benzodiazepines; Cells, Cultured; Chloride Channels; Dose-Response Relationship, Drug; Drug Interactions; Female; Flumazenil; GABA Modulators; Hepatic Encephalopathy; Hippocampus; Male; Neural Inhibition; Neurons; Patch-Clamp Techniques; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A; Synaptic Transmission | 2006 |
Increased levels of pregnenolone and its neuroactive metabolite allopregnanolone in autopsied brain tissue from cirrhotic patients who died in hepatic coma.
Topics: Adult; Aged; Aged, 80 and over; Animals; Benzodiazepines; Brain Chemistry; Desoxycorticosterone; Female; Flunitrazepam; GABA Agonists; GABA Modulators; Gas Chromatography-Mass Spectrometry; Hepatic Encephalopathy; Humans; In Vitro Techniques; Liver Cirrhosis; Male; Membranes; Middle Aged; Muscimol; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reference Standards | 2006 |
Indomethacin improves locomotor deficit and reduces brain concentrations of neuroinhibitory steroids in rats following portacaval anastomosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Ataxia; Brain; Brain Chemistry; Desoxycorticosterone; Hepatic Encephalopathy; Humans; Indomethacin; Male; Molecular Structure; Motor Activity; Portacaval Shunt, Surgical; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Steroids | 2008 |