pregnanolone has been researched along with Fra(X) Syndrome in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adams, P; Brinton, RD; Carrillo, NR; Giulivi, C; Hagerman, RJ; Irwin, RW; Kim, K; Lubarr, N; Olichney, JM; Rivera, SM; Rogawski, MA; Schneider, A; Tassone, F; Trivedi, AM; Wang, JY; Wu, CY; Yang, J | 1 |
| Budimirovic, DB | 1 |
| Carrillo, NR; Giulivi, C; Hagerman, RJ; Napoli, E; Rogawski, M; Schneider, A; Tassone, F; Trivedi, A; Wang, JY | 1 |
| Hagerman, RJ; Martinez-Cerdeno, V; Salcedo-Arellano, MJ | 1 |
| Braat, S; Kooy, RF | 1 |
| Bagni, C; Braat, S; D'Hulst, C; De Deyn, PP; De Rubeis, S; Heulens, I; Kooy, RF; Mientjes, E; Nelson, DL; Van Dam, D; Willemsen, R | 1 |
| Ackley, MA; Corbin, JG; Doherty, JJ; Huntsman, MM; Loya, CM; Martin, BS; Martinez-Botella, G; Robichaud, AJ; Salituro, FG | 1 |
| Cao, Z; Hagerman, PJ; Hagerman, RJ; Hulsizer, S; Pessah, IN; Rogawski, MA; Tang, HT; Tassone, F | 1 |
2 review(s) available for pregnanolone and Fra(X) Syndrome
| Article | Year |
|---|---|
[Fragile X associated tremor/ataxia syndrome: its clinical presentation, pathology, and treatment].
Topics: Antidepressive Agents; Ataxia; Brain; Deep Brain Stimulation; Female; Fragile X Mental Retardation Protein; Fragile X Syndrome; Humans; Male; Memantine; Neurologic Examination; Pregnanolone; Symptom Assessment; Tremor | 2019 |
Insights into GABAAergic system deficits in fragile X syndrome lead to clinical trials.
Topics: Animals; Brain; Clinical Trials as Topic; Disease Models, Animal; Fragile X Syndrome; GABA Modulators; Humans; Pregnanolone; Receptors, GABA-A | 2015 |
2 trial(s) available for pregnanolone and Fra(X) Syndrome
| Article | Year |
|---|---|
Open-Label Allopregnanolone Treatment of Men with Fragile X-Associated Tremor/Ataxia Syndrome.
Topics: Administration, Intravenous; Aged; Ataxia; Brain; Fragile X Syndrome; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Pregnanolone; Treatment Outcome; Tremor | 2017 |
Allopregnanolone Treatment Improves Plasma Metabolomic Profile Associated with GABA Metabolism in Fragile X-Associated Tremor/Ataxia Syndrome: a Pilot Study.
Topics: Aged; Anxiety; Ataxia; Depression; Energy Metabolism; Fragile X Syndrome; gamma-Aminobutyric Acid; Humans; Male; Metabolomics; Middle Aged; Mitochondria; Ornithine; Oxidative Stress; Pilot Projects; Pregnanolone; Tremor | 2019 |
4 other study(ies) available for pregnanolone and Fra(X) Syndrome
| Article | Year |
|---|---|
Can a Neurosteroid Ameliorate Fragile X-Associated Tremor/Ataxia Syndrome?
Topics: Ataxia; Fragile X Syndrome; Humans; Male; Neurotransmitter Agents; Pregnanolone; Tremor | 2017 |
The GABAA receptor is an FMRP target with therapeutic potential in fragile X syndrome.
Topics: Animals; Fragile X Mental Retardation Protein; Fragile X Syndrome; GABA-A Receptor Antagonists; Genotype; Humans; Male; Mice; Mice, Knockout; Mice, Transgenic; Pregnanolone; Receptors, GABA-A; RNA, Messenger | 2015 |
Rescue of deficient amygdala tonic γ-aminobutyric acidergic currents in the Fmr-/y mouse model of fragile X syndrome by a novel γ-aminobutyric acid type A receptor-positive allosteric modulator.
Topics: Amygdala; Animals; Animals, Newborn; CHO Cells; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; Fragile X Mental Retardation Protein; Fragile X Syndrome; GABA Agents; GABA Modulators; gamma-Aminobutyric Acid; Heterocyclic Compounds, 2-Ring; In Vitro Techniques; Membrane Potentials; Mice; Mice, Knockout; Patch-Clamp Techniques; Pregnanolone; Receptors, GABA-A; Transfection | 2016 |
Clustered burst firing in FMR1 premutation hippocampal neurons: amelioration with allopregnanolone.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; Cells, Cultured; Excitatory Amino Acid Antagonists; Fragile X Mental Retardation Protein; Fragile X Syndrome; GABA Plasma Membrane Transport Proteins; Gene Knock-In Techniques; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neurons; Pregnanolone; Receptor, Metabotropic Glutamate 5; Receptors, Glutamate; Receptors, Metabotropic Glutamate; RNA, Messenger; Trinucleotide Repeat Expansion | 2012 |