Page last updated: 2024-08-23

pregnanolone and Drug Withdrawal Symptoms

pregnanolone has been researched along with Drug Withdrawal Symptoms in 43 studies

Research

Studies (43)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	7 (16.28)	18.2507
2000's	23 (53.49)	29.6817
2010's	12 (27.91)	24.3611
2020's	1 (2.33)	2.80

Authors

Authors	Studies
Cao, W; Duffy, KA; Epperson, CN; Johnson, RL; Kuzma, A; Loughead, J; Morrow, AL; Novick, AM; Sammel, MD; Sofuoglu, M; Strasser, AA	1
Crabbe, JC; Finn, DA; Ford, MM; Helms, ML; Jensen, JP; Nipper, MA; Rossi, DJ	1
Chopde, CT; Thakre, PP; Tundulwar, MR; Ugale, RR	1
Mohammad, A; Ramroop, J; Shen, H; Smith, SS	1
al'Absi, M; Allen, AM; Allen, SS; Hatsukami, D; Lando, H	1
Cozzoli, DK; Crabbe, JC; Finn, DA; Ford, MM; Helms, M; Jensen, JP; Ramaker, MJ; Rossi, DJ; Snelling, C; Tanchuck-Nipper, MA	1
Beadles-Bohling, A; Cozzoli, DK; Finn, DA; Ford, MM; Hertzberg, A; Tanchuck-Nipper, MA	1
Diaz-Granados, JL; Matthews, DB; Novier, A; Ornelas, LC	1
Beadles-Bohling, AS; Crabbe, JC; Finn, DA; Ford, MM; Gililland-Kaufman, KR; Mark, GP; Snelling, C; Tanchuck, MA	1
Beckley, EH; Finn, DA; Ford, MM; Kaufman, KR	1
Crabbe, JC; Finn, DA; Ford, MM; Hashimoto, J; Long, SL; Roselli, CE; Tanchuck, MA; Wiren, KM	1
Finn, DA; Kaufman, KR; Strong, MN; Tanchuck, MA	1
Andreen, L; Backstrom, T; Johansson, IM; Turkmen, S; Wahlstrom, G	1
Finn, DA; Finn, TJ; Kaufman, KR; Ronnekleiv-Kelly, SM; Roselli, CE; Tanchuck, MA	1
Gangisetty, O; Gould, J; Reddy, DS	1
Biggio, F; Biggio, G; Cabras, S; Cocco, PL; Follesa, P; Gorini, G; Manca, A; Mancuso, L; Marra, C; Mascia, MP; Purdy, RH	1
Chopde, CT; Hirani, K; Khisti, RT	1
Bernardi, G; di Michele, F; Pace, M; Pasinib, A; Pompili, E; Romeo, E; Rupprecht, R	1
Crabbe, JC; Finn, DA; Ford, MM; Roselli, CE; Wiren, KM	1
Crabbe, JC; Finn, DA; Long, SL; Tanchuck, MA	1
Biggio, G; Brundu, A; Concas, A; Marra, C; Porcu, P; Sogliano, C	1
Biggio, F; Biggio, G; Follesa, P; Murru, L; Sanna, E; Serra, M; Talani, G	1
Martin-Garcia, E; Pallares, M	1
Cutler, SM; Stein, DG; Vanlandingham, JW	1
Biggio, F; Caria, S; Follesa, P; Gorini, G; Mostallino, MC; Murru, L; Sanna, E	1
France, CP; Javors, MA; McMahon, LR	1
Chopde, CT; Hirani, K; Kokare, DM; Sharma, AN; Ugale, RR	1
Beckley, EH; Finn, DA	1
Andersson, A; Bäckström, T; Bixo, M; Nyberg, S; Sundström-Poromaa, I; Wihlbäck, AC	1
Beckley, EH; Crabbe, JC; Finn, DA; Fretwell, AM; Gililland, KR; Tanchuck, MA	1
Costa, AM; ffrench-Mullen, JM; Smith, SS; Spence, KT	1
Brailowsky, S; Calixto, E; Lemini, C; Montiel, T	1
Gallo, MA; Smith, SS	1
Finn, DA; Gallaher, EJ; Lotrich, F; Roberts, AJ	1
Kulkarni, SK; Reddy, DS	1
Bitran, D; Frye, CA; Gong, QH; Hsu, FC; Li, X; Moran, MH; Smith, SS	1
Moran, MH; Smith, SS	1
Crabbe, JC; Finn, DA; Gallaher, EJ	1
Bargas, J; Brailowsky, S; Calixto, E; Casasola, C; López-Colomé, AM; Montiel, T	1
Crabbe, JC; Finn, DA; Reilly, MT; Rustay, NR	1
Reddy, DS; Rogawski, MA	1
Kim, HY; Reddy, DS; Rogawski, MA	1
Smith, SS	1

Reviews

4 review(s) available for pregnanolone and Drug Withdrawal Symptoms

Article	Year
Manipulation of GABAergic steroids: Sex differences in the effects on alcohol drinking- and withdrawal-related behaviors. Hormones and behavior, 2010, Volume: 57, Issue:1 Topics: Alcohol Drinking; Alcoholism; Animals; Disease Models, Animal; Female; GABA Agonists; GABA-A Receptor Agonists; Male; Mice; Pregnanolone; Rats; Receptors, GABA-A; Reinforcement, Psychology; Sex Characteristics; Sex Factors; Substance Withdrawal Syndrome	2010
Tolerance to allopregnanolone with focus on the GABA-A receptor. British journal of pharmacology, 2011, Volume: 162, Issue:2 Topics: Animals; Drug Tolerance; Female; gamma-Aminobutyric Acid; Gonadal Steroid Hormones; Humans; Pregnancy; Pregnanolone; Progesterone; Rats; Receptors, GABA-A; RNA, Messenger; Stress, Psychological; Substance Withdrawal Syndrome; Time Factors	2011
The role of pregnane neurosteroids in ethanol withdrawal: behavioral genetic approaches. Pharmacology & therapeutics, 2004, Volume: 101, Issue:2 Topics: Alcohol-Related Disorders; Animals; Cholestenone 5 alpha-Reductase; Chromosome Mapping; Disease Models, Animal; Ethanol; Mice; Pregnanes; Pregnanolone; Receptors, GABA-A; Receptors, Neurotransmitter; Substance Withdrawal Syndrome	2004
Neurosteroids, GABAA receptors, and ethanol dependence. Psychopharmacology, 2006, Volume: 186, Issue:3 Topics: Alcoholism; Animals; Brain; Ethanol; Gene Expression Regulation; Humans; Neurons; Pregnanolone; Receptors, GABA-A; RNA, Messenger; Substance Withdrawal Syndrome	2006

Trials

4 trial(s) available for pregnanolone and Drug Withdrawal Symptoms

Article	Year
Effect of progesterone administration in male and female smokers on nicotine withdrawal and neural response to smoking cues: role of progesterone conversion to allopregnanolone. Biology of sex differences, 2022, 10-23, Volume: 13, Issue:1 Topics: Cross-Over Studies; Cues; Fatigue; Female; Humans; Neurosteroids; Nicotine; Pregnanolone; Progesterone; Smokers; Smoking; Substance Withdrawal Syndrome	2022
Menstrual phase, depressive symptoms, and allopregnanolone during short-term smoking cessation. Experimental and clinical psychopharmacology, 2013, Volume: 21, Issue:6 Topics: Adolescent; Adult; Comorbidity; Cross-Over Studies; Depression; Female; Follicular Phase; Humans; Luteal Phase; Pregnanolone; Recurrence; Smoking; Smoking Cessation; Smoking Prevention; Substance Withdrawal Syndrome; Young Adult	2013
Effects of fluoxetine, indomethacine and placebo on 3 alpha, 5 alpha tetrahydroprogesterone (THP) plasma levels in uncomplicated alcohol withdrawal. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2000, Volume: 1, Issue:2 Topics: Adult; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Ethanol; Fluoxetine; gamma-Aminobutyric Acid; Humans; Indomethacin; Male; Pregnanolone; Selective Serotonin Reuptake Inhibitors; Substance Withdrawal Syndrome	2000
Allopregnanolone serum concentrations and neurosteroid sensitivity during withdrawal from postmenopausal hormone therapy. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2007, Volume: 23, Issue:10 Topics: Cross-Over Studies; Double-Blind Method; Estradiol; Estrogen Replacement Therapy; Female; Gonadal Steroid Hormones; Humans; Middle Aged; Pregnanolone; Progesterone; Saccades; Substance Withdrawal Syndrome	2007

Other Studies

35 other study(ies) available for pregnanolone and Drug Withdrawal Symptoms

Article	Year
Ethanol withdrawal-induced dysregulation of neurosteroid levels in plasma, cortex, and hippocampus in genetic animal models of high and low withdrawal. Psychopharmacology, 2017, Volume: 234, Issue:18 Topics: Administration, Inhalation; Alcoholism; Animals; Cerebral Cortex; Disease Models, Animal; Ethanol; Female; Hippocampus; Male; Mice; Mice, Inbred DBA; Mice, Transgenic; Neurotransmitter Agents; Pregnanolone; Substance Withdrawal Syndrome	2017
Neurosteroid allopregnanolone attenuates development of nicotine withdrawal behavior in mice. Neuroscience letters, 2013, Apr-29, Volume: 541 Topics: Animals; Anxiety; Finasteride; Indomethacin; Male; Maze Learning; Mice; Motor Activity; Neurotransmitter Agents; Nicotine; Pregnanolone; Progesterone; Substance Withdrawal Syndrome; Time Factors	2013
A stress steroid triggers anxiety via increased expression of α4βδ GABAA receptors in methamphetamine dependence. Neuroscience, 2013, Dec-19, Volume: 254 Topics: Amphetamine-Related Disorders; Animals; Anxiety; Gene Expression Regulation; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Pregnanolone; Rats; Rats, Long-Evans; Receptors, GABA-A; Sensory Gating; Stress, Psychological; Substance Withdrawal Syndrome	2013
Quantification of ten neuroactive steroids in plasma in Withdrawal Seizure-Prone and -Resistant mice during chronic ethanol withdrawal. Psychopharmacology, 2014, Volume: 231, Issue:17 Topics: Animals; Central Nervous System Depressants; Chronic Disease; Ethanol; Male; Mice; Neurotransmitter Agents; Pregnanolone; Receptors, GABA-A; Reproducibility of Results; Seizures; Substance Withdrawal Syndrome	2014
Sex Differences in Ethanol's Anxiolytic Effect and Chronic Ethanol Withdrawal Severity in Mice with a Null Mutation of the 5α-Reductase Type 1 Gene. Behavior genetics, 2015, Volume: 45, Issue:3 Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Alcohol Drinking; Animals; Anti-Anxiety Agents; Behavior, Animal; Corticosterone; Ethanol; Female; Gene Deletion; Genotype; Male; Maze Learning; Membrane Proteins; Mice; Mice, Knockout; Mutation; Pregnanolone; Sex Characteristics; Sex Factors; Substance Withdrawal Syndrome	2015
Differences in Behavioral Responding in Adult and Aged Rats Following Chronic Ethanol Exposure. Alcoholism, clinical and experimental research, 2016, Volume: 40, Issue:7 Topics: Aging; Animals; Ethanol; Male; Maze Learning; Motor Activity; Pregnanolone; Rats; Substance Withdrawal Syndrome	2016
The neurosteroid environment in the hippocampus exerts bi-directional effects on seizure susceptibility in mice. Brain research, 2008, Dec-03, Volume: 1243 Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Alcohol-Induced Disorders, Nervous System; Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epilepsy; Finasteride; Genetic Predisposition to Disease; Hippocampus; Mice; Mice, Transgenic; Neurons; Pentylenetetrazole; Pregnanolone; Substance Withdrawal Syndrome	2008
Selected line difference in the effects of ethanol dependence and withdrawal on allopregnanolone levels and 5alpha-reductase enzyme activity and expression. Alcoholism, clinical and experimental research, 2009, Volume: 33, Issue:12 Topics: Administration, Inhalation; Alcoholism; Animals; Brain; Brain Chemistry; Central Nervous System Depressants; Ethanol; Gene Expression Regulation, Enzymologic; Hippocampus; Hydrocortisone; Male; Mice; Mice, Inbred Strains; Oxidoreductases; Pregnanolone; Radioimmunoassay; Reverse Transcriptase Polymerase Chain Reaction; Species Specificity; Substance Withdrawal Syndrome	2009
Replacement with GABAergic steroid precursors restores the acute ethanol withdrawal profile in adrenalectomy/gonadectomy mice. Neuroscience, 2010, Mar-10, Volume: 166, Issue:1 Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Acute Disease; Alcohol-Induced Disorders, Nervous System; Animals; Castration; Central Nervous System Depressants; Desoxycorticosterone; Disease Models, Animal; Enzyme Inhibitors; Ethanol; Female; Finasteride; gamma-Aminobutyric Acid; Male; Mice; Neural Inhibition; Neurotransmitter Agents; Pregnanolone; Progesterone; Receptors, GABA-A; Substance Withdrawal Syndrome	2010
Localization of brain 5α-reductase messenger RNA in mice selectively bred for high chronic alcohol withdrawal severity. Alcohol (Fayetteville, N.Y.), 2011, Volume: 45, Issue:8 Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Amygdala; Animals; Brain; Cerebral Cortex; Ethanol; Gene Expression; Hippocampus; Hypothalamus; Male; Membrane Proteins; Mice; Pregnanolone; RNA, Messenger; Substance Withdrawal Syndrome; Thalamus	2011
A mouse kindling model of perimenstrual catamenial epilepsy. The Journal of pharmacology and experimental therapeutics, 2012, Volume: 341, Issue:3 Topics: 5-alpha Reductase Inhibitors; Animals; Diazepam; Disease Models, Animal; Epilepsy; Female; Finasteride; Gonadotropins; Hippocampus; Kindling, Neurologic; Menstrual Cycle; Mice; Mice, Inbred C57BL; Pregnanolone; Progesterone; Rats; Real-Time Polymerase Chain Reaction; Receptors, GABA-A; RNA, Messenger; Substance Withdrawal Syndrome	2012
Changes in GABA(A) receptor gene expression induced by withdrawal of, but not by long-term exposure to, ganaxolone in cultured rat cerebellar granule cells. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3 Topics: Animals; Cells, Cultured; Cerebellum; Electrophysiology; Female; Gene Expression Regulation; Pregnanolone; Protein Subunits; Rats; Receptors, GABA-A; RNA, Messenger; Substance Withdrawal Syndrome; Xenopus laevis	2002
Behavioral action of ethanol in Porsolt's forced swim test: modulation by 3 alpha-hydroxy-5 alpha-pregnan-20-one. Neuropharmacology, 2002, Volume: 43, Issue:8 Topics: Adrenalectomy; Animals; Depression; Dose-Response Relationship, Drug; Ethanol; Immobilization; Male; Mice; Motor Activity; Pregnanolone; Substance Withdrawal Syndrome; Swimming	2002
Interaction of chronic ethanol exposure and finasteride: sex and strain differences. Pharmacology, biochemistry, and behavior, 2004, Volume: 78, Issue:3 Topics: Animals; Area Under Curve; Ethanol; Female; Finasteride; Male; Mice; Pregnanolone; Sex Characteristics; Species Specificity; Substance Withdrawal Syndrome	2004
Neurosteroids in nicotine and morphine dependence. Psychopharmacology, 2006, Volume: 186, Issue:3 Topics: Analgesics, Opioid; Animals; Cerebral Cortex; Male; Mecamylamine; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Antagonists; Pregnanolone; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome	2006
Effects of intrahippocampal nicotine and neurosteroid administration on withdrawal in voluntary and chronic alcohol-drinking rats. Alcoholism, clinical and experimental research, 2005, Volume: 29, Issue:9 Topics: Animals; Body Weight; Ethanol; Hippocampus; Male; Motor Activity; Nicotine; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Seizures; Substance Withdrawal Syndrome	2005
Tapered progesterone withdrawal promotes long-term recovery following brain trauma. Experimental neurology, 2006, Volume: 200, Issue:2 Topics: Anesthetics; Animals; Behavior, Animal; Blotting, Western; Brain Injuries; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Drug Administration Schedule; Glial Fibrillary Acidic Protein; HSP70 Heat-Shock Proteins; Immunohistochemistry; Male; Motor Activity; Peptides, Cyclic; Perceptual Disorders; Pregnanolone; Random Allocation; Rats; Rats, Sprague-Dawley; Recovery of Function; Substance Withdrawal Syndrome; Time Factors; Tumor Suppressor Protein p53; Upper Extremity	2006
Plastic neuronal changes in GABA(A) receptor gene expression induced by progesterone metabolites: in vitro molecular and functional studies. Pharmacology, biochemistry, and behavior, 2006, Volume: 84, Issue:4 Topics: Animals; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Desoxycorticosterone; DNA, Complementary; Electrophysiology; Fluorescent Antibody Technique; Gene Expression; Neuronal Plasticity; Patch-Clamp Techniques; Pregnanolone; Progesterone; Rats; Receptors, GABA-A; RNA, Messenger; Substance Withdrawal Syndrome	2006
Changes in relative potency among positive GABA(A) receptor modulators upon discontinuation of chronic benzodiazepine treatment in rhesus monkeys. Psychopharmacology, 2007, Volume: 192, Issue:1 Topics: Animals; Behavior, Animal; Benzodiazepines; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Modulators; Lorazepam; Macaca mulatta; Male; Midazolam; Pentobarbital; Pregnanediones; Pregnanolone; Receptors, GABA-A; Substance Withdrawal Syndrome	2007
Chronic progesterone treatment augments while dehydroepiandrosterone sulphate prevents tolerance to ethanol anxiolysis and withdrawal anxiety in rats. European journal of pharmacology, 2007, Jul-19, Volume: 567, Issue:3 Topics: Animals; Anxiety; Central Nervous System Depressants; Dehydroepiandrosterone Sulfate; Drug Tolerance; Enzyme Inhibitors; Ethanol; Finasteride; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Substance Withdrawal Syndrome	2007
Inhibition of progesterone metabolism mimics the effect of progesterone withdrawal on forced swim test immobility. Pharmacology, biochemistry, and behavior, 2007, Volume: 87, Issue:4 Topics: 5-alpha Reductase Inhibitors; Animals; Depression; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Finasteride; Mice; Mice, Inbred DBA; Motor Activity; Pregnanolone; Progesterone; Substance Withdrawal Syndrome; Swimming	2007
Decreased anticonvulsant efficacy of allopregnanolone during ethanol withdrawal in female Withdrawal Seizure-Prone vs. Withdrawal Seizure-Resistant mice. Neuropharmacology, 2008, Volume: 54, Issue:2 Topics: Animals; Anticonvulsants; Central Nervous System Depressants; Corticosterone; Estradiol; Ethanol; Female; Mice; Pregnanolone; Progesterone; Radioimmunoassay; Seizures; Substance Withdrawal Syndrome	2008
Withdrawal from the endogenous steroid progesterone results in GABAA currents insensitive to benzodiazepine modulation in rat CA1 hippocampus. Journal of neurophysiology, 1995, Volume: 74, Issue:1 Topics: Animals; Benzodiazepines; Brain Chemistry; Chloride Channels; Electrophysiology; Female; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; Ion Channel Gating; Lorazepam; Picrotoxin; Pregnanolone; Progesterone; Rats; Receptors, GABA-A; Substance Withdrawal Syndrome	1995
Allopregnanolone potentiates a GABA-withdrawal syndrome in the rat cerebral cortex. Neuroscience letters, 1995, Aug-04, Volume: 195, Issue:2 Topics: Animals; Anti-Anxiety Agents; Cerebral Cortex; Disease Models, Animal; Drug Synergism; Electroencephalography; Epilepsies, Partial; gamma-Aminobutyric Acid; Male; Neurons; Pregnanolone; Rats; Rats, Wistar; Substance Withdrawal Syndrome	1995
Progesterone withdrawal decreases latency to and increases duration of electrified prod burial: a possible rat model of PMS anxiety. Pharmacology, biochemistry, and behavior, 1993, Volume: 46, Issue:4 Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Diazepam; Disease Models, Animal; Electroshock; Estradiol; Female; Indomethacin; Pregnanolone; Premenstrual Syndrome; Progesterone; Rats; Substance Withdrawal Syndrome	1993
Genetic differences in behavioral sensitivity to a neuroactive steroid. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:2 Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Ataxia; Avoidance Learning; Dose-Response Relationship, Drug; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Muscle Relaxation; Pentylenetetrazole; Pregnanolone; Seizures; Species Specificity; Substance Withdrawal Syndrome	1997
Chronic neurosteroid treatment prevents the development of morphine tolerance and attenuates abstinence behavior in mice. European journal of pharmacology, 1997, Oct-15, Volume: 337, Issue:1 Topics: Analgesics, Opioid; Animals; Dehydroepiandrosterone; Drug Tolerance; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Pregnanolone; Pregnenolone; Reaction Time; Steroids; Substance Withdrawal Syndrome	1997
Withdrawal from 3alpha-OH-5alpha-pregnan-20-One using a pseudopregnancy model alters the kinetics of hippocampal GABAA-gated current and increases the GABAA receptor alpha4 subunit in association with increased anxiety. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Jul-15, Volume: 18, Issue:14 Topics: Animals; Anxiety; Female; GABA Agonists; GABA Antagonists; GABA Modulators; Hippocampus; Ion Channel Gating; Kinetics; Maze Learning; Peptide Fragments; Pregnanolone; Progesterone; Pseudopregnancy; Rats; Receptors, GABA-A; Substance Withdrawal Syndrome	1998
Progesterone withdrawal I: pro-convulsant effects. Brain research, 1998, Oct-05, Volume: 807, Issue:1-2 Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Drug Synergism; Female; GABA Modulators; Pregnanolone; Progesterone; Pseudopregnancy; Rats; Rats, Long-Evans; Seizures; Substance Withdrawal Syndrome	1998
Differential change in neuroactive steroid sensitivity during ethanol withdrawal. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:1 Topics: Administration, Inhalation; Alcohol Withdrawal Seizures; Animals; Anticonvulsants; Anxiety; Ataxia; Behavior, Animal; Dose-Response Relationship, Drug; Ethanol; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Muscle Relaxation; Pentylenetetrazole; Pregnanolone; Radioimmunoassay; Species Specificity; Steroids; Substance Withdrawal Syndrome; Time Factors	2000
Neocortical hyperexcitability after GABA withdrawal in vitro. Epilepsy research, 2000, Volume: 39, Issue:1 Topics: Animals; Flunitrazepam; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Muscimol; Neocortex; Pregnanolone; Progesterone; Rats; Rats, Wistar; Seizures; Substance Withdrawal Syndrome; Synaptic Transmission	2000
Acute neuroactive steroid withdrawal in withdrawal seizure-prone and withdrawal seizure-resistant mice. Pharmacology, biochemistry, and behavior, 2000, Volume: 67, Issue:4 Topics: Animals; Breeding; Hypothermia; Male; Mice; Pregnanolone; Receptors, GABA-A; Seizures; Steroid Hydroxylases; Substance Withdrawal Syndrome	2000
Enhanced anticonvulsant activity of neuroactive steroids in a rat model of catamenial epilepsy. Epilepsia, 2001, Volume: 42, Issue:3 Topics: Allosteric Regulation; Animals; Anticonvulsants; Benzodiazepinones; Desoxycorticosterone; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Female; Menstrual Cycle; Pentylenetetrazole; Phenobarbital; Pregnanolone; Pseudopregnancy; Rats; Rats, Sprague-Dawley; Receptors, GABA; Steroids; Substance Withdrawal Syndrome; Valproic Acid	2001
Neurosteroid withdrawal model of perimenstrual catamenial epilepsy. Epilepsia, 2001, Volume: 42, Issue:3 Topics: 20-alpha-Dihydroprogesterone; Adult; Animals; Behavior, Animal; Disease Models, Animal; Disease Susceptibility; Epilepsy; Female; Finasteride; Gonadotropins, Equine; Humans; Menstrual Cycle; Pentylenetetrazole; Pregnanolone; Progesterone; Pseudopregnancy; Rats; Rats, Sprague-Dawley; Receptors, GABA; Steroids; Substance Withdrawal Syndrome	2001
Withdrawal properties of a neuroactive steroid: implications for GABA(A) receptor gene regulation in the brain and anxiety behavior. Steroids, 2002, Volume: 67, Issue:6 Topics: Animals; Anxiety; Behavior, Animal; Brain; Female; Gene Expression Regulation; Pregnanolone; Rats; Receptors, GABA-A; Seizures; Steroids; Substance Withdrawal Syndrome; Synaptic Transmission; Time	2002