pregnanolone and Disease Models, Animal

Topics: Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Mice; Motor Neurons; Neuroprotective Agents; Pregnanolone; Progesterone; Spinal Cord

Topics: Animals; Brain; Clinical Trials as Topic; Disease Models, Animal; Fragile X Syndrome; GABA Modulators; Humans; Pregnanolone; Receptors, GABA-A

Topics: Alcohol Drinking; Alcoholism; Animals; Disease Models, Animal; Female; GABA Agonists; GABA-A Receptor Agonists; Male; Mice; Pregnanolone; Rats; Receptors, GABA-A; Reinforcement, Psychology; Sex Characteristics; Sex Factors; Substance Withdrawal Syndrome

Topics: Affect; Alzheimer Disease; Animals; Brain; Cognition; Disease Models, Animal; Emotions; Female; Humans; Neurotransmitter Agents; Pregnancy; Pregnanolone; Sexual Behavior, Animal; Social Behavior

Topics: Animals; Brain; Disease Models, Animal; Drug Evaluation, Preclinical; Fluoxetine; Humans; Mice; Pregnanolone; Receptors, GABA-A; Selective Serotonin Reuptake Inhibitors; Social Isolation; Stress Disorders, Post-Traumatic

Topics: Animals; Anxiety; Behavior, Animal; Brain; Disease Models, Animal; Fluoxetine; Mice; Neurotransmitter Agents; Pregnanolone; Selective Serotonin Reuptake Inhibitors; Stress Disorders, Post-Traumatic; Up-Regulation

Topics: Alcohol-Related Disorders; Animals; Cholestenone 5 alpha-Reductase; Chromosome Mapping; Disease Models, Animal; Ethanol; Mice; Pregnanes; Pregnanolone; Receptors, GABA-A; Receptors, Neurotransmitter; Substance Withdrawal Syndrome

Topics: Animals; Anticonvulsants; Brain Chemistry; Disease Models, Animal; Epilepsy; Female; Humans; Menstruation Disturbances; Models, Molecular; Pregnanolone; Progesterone; Receptors, GABA-A; Steroids

Topics: Acetamides; Amines; Animals; Anticonvulsants; Benzodiazepines; Carbamates; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Design; Gabapentin; gamma-Aminobutyric Acid; Humans; Lacosamide; Levetiracetam; Phenylenediamines; Piracetam; Pregabalin; Pregnanolone; Pyrrolidinones; Triazoles

Topics: Animals; Disease Models, Animal; Gonadal Steroid Hormones; Humans; Mice; Niemann-Pick Disease, Type C; Pregnanolone; Receptors, GABA-A

Topics: Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Mice; Mice, Transgenic; Nerve Regeneration; Neuroprotective Agents; Pregnanolone; Rats; tau Proteins

Topics: 20-alpha-Dihydroprogesterone; Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Disease Models, Animal; Mice; Pregnanolone; Psychotic Disorders; Receptors, GABA-A; Selective Serotonin Reuptake Inhibitors; Social Isolation

Topics: Anhedonia; Animals; Antidepressive Agents; Depression, Postpartum; Disease Models, Animal; Female; Humans; Ketamine; Maternal Deprivation; Mice; Pregnanolone

Topics: Animals; Animals, Newborn; Anticonvulsants; Asphyxia Neonatorum; Disease Models, Animal; Epilepsy; Humans; Infant, Newborn; Phenobarbital; Pregnanolone; Seizures; Sheep

Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Carrier Proteins; Corticosterone; Depression; Depression, Postpartum; Disease Models, Animal; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Fluoxetine; Glucosides; Hippocampus; Humans; Monoterpenes; Pregnancy; Pregnanolone; Progesterone; Rats; Receptors, GABA-A; Stress, Psychological; Sucrose; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha

Topics: Animals; Disease Models, Animal; Female; Male; Mice; Pregnanolone; Stereotyped Behavior; Tics; Tourette Syndrome

Topics: Angiogenic Proteins; Animals; Bile Acids and Salts; Bilirubin; Chenodeoxycholic Acid; Cholestasis; Cholesterol 7-alpha-Hydroxylase; Cholic Acid; Cytokines; Disease Models, Animal; Gastrointestinal Microbiome; Inflammation; Lacticaseibacillus rhamnosus; Liver; Male; Mice; Mice, Inbred C57BL; Pregnanolone; Probiotics; RNA-Binding Proteins; Signal Transduction; Ursodeoxycholic Acid

Topics: Alzheimer Disease; Animals; Brain; Disease Models, Animal; Energy Metabolism; Female; Gene Expression; Lipid Peroxidation; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Pregnanolone

Topics: Animals; Behavior, Animal; Carrier Proteins; Corticosterone; Disease Models, Animal; gamma-Aminobutyric Acid; Hippocampus; Hypothalamo-Hypophyseal System; Imidazoles; Male; Prefrontal Cortex; Pregnanolone; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Selective Serotonin Reuptake Inhibitors; Sertraline; Stress Disorders, Post-Traumatic

Topics: Animals; Association Learning; Behavior, Animal; CA1 Region, Hippocampal; CA2 Region, Hippocampal; Cognitive Dysfunction; Dendritic Spines; Disease Models, Animal; Estrous Cycle; Female; Learning; Memory, Long-Term; Memory, Short-Term; Ovariectomy; Pregnanolone; Progesterone; Pyramidal Cells; Rats, Wistar; Recognition, Psychology

Topics: Animals; Anticonvulsants; beta-Cyclodextrins; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Drug Therapy, Combination; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Midazolam; Neurosteroids; Patch-Clamp Techniques; Pregnanolone; Receptors, GABA-A; Seizures; Tiagabine

Topics: Analgesics; Animals; Antineoplastic Agents; Disease Models, Animal; Docetaxel; Duloxetine Hydrochloride; Epirubicin; Female; Neoadjuvant Therapy; Neuralgia; Pain; Pain Measurement; Peripheral Nervous System Diseases; Pregnanolone; Sciatic Nerve

Topics: Animals; Antidepressive Agents; Azepines; Behavior, Animal; Benzamides; Brain-Derived Neurotrophic Factor; Depression; Disease Models, Animal; Excitatory Amino Acid Antagonists; Helplessness, Learned; Male; Pregnanolone; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, trkB; Receptors, AMPA; Signal Transduction

Topics: Animals; Disease Models, Animal; Electrocorticography; Epilepsy; Hippocampus; Male; Neocortex; Pregnanolone; Rats; Rats, Sprague-Dawley; Status Epilepticus

Topics: Animals; Antidepressive Agents; Behavior, Animal; CA1 Region, Hippocampal; Depression; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Glutamate-Ammonia Ligase; Helplessness, Learned; Male; Nucleus Accumbens; Pregnanolone; Rats; Rats, Sprague-Dawley

Topics: Animals; Anticonvulsants; Antioxidants; Brain; Brain Chemistry; Dihydrotestosterone; Disease Models, Animal; Estradiol; gamma-Aminobutyric Acid; Hydrocortisone; Male; Neuroprotective Agents; Normetanephrine; Oxadiazoles; Oxidative Stress; Pentylenetetrazole; Pregnanolone; Progesterone; Reactive Oxygen Species; Seizures; Serotonin; Zebrafish

Topics: 1-Deoxynojirimycin; 2-Hydroxypropyl-beta-cyclodextrin; Animals; Cyclodextrins; Disease Models, Animal; Drug Therapy, Combination; Female; Male; Mice; Mice, Inbred BALB C; Niemann-Pick Disease, Type C; Pregnanolone

Topics: Animals; Behavior, Animal; Disease Models, Animal; Estrous Cycle; Female; HIV Infections; HIV-1; Humans; Hypothalamo-Hypophyseal System; Mice; Motor Activity; Neurosecretory Systems; Oxycodone; Pituitary-Adrenal System; Pregnanolone; Psychomotor Performance; Steroids; tat Gene Products, Human Immunodeficiency Virus

Topics: 1-Deoxynojirimycin; 2-Hydroxypropyl-beta-cyclodextrin; Animals; Apoptosis; beta-Cyclodextrins; Cell Proliferation; Disease Models, Animal; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mutation; Niemann-Pick C1 Protein; Niemann-Pick Disease, Type C; Olfactory Mucosa; Pregnanolone; Proteins

Topics: 5-alpha Reductase Inhibitors; Animals; Anxiety Disorders; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Finasteride; Freezing Reaction, Cataleptic; Male; Mice, Inbred C57BL; Muscle Relaxants, Central; Muscle Strength; Muscle Tonus; Pregnanediones; Pregnanolone; Restraint, Physical; Stress, Psychological

Topics: Anesthetics; Animals; Brain; Brain Waves; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Fourier Analysis; Male; Muscarinic Agonists; Pilocarpine; Pregnanolone; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric

Topics: Animals; Disease Models, Animal; Female; Fetal Development; Fetal Growth Retardation; Guinea Pigs; Hippocampus; Hydrocortisone; Pregnancy; Pregnancy Complications; Pregnanolone; Prenatal Exposure Delayed Effects; Stress, Psychological

Topics: Action Potentials; Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Electroshock; Fragile X Mental Retardation Protein; gamma-Aminobutyric Acid; Hippocampus; Kindling, Neurologic; Male; Mice; Mice, Knockout; Pentylenetetrazole; Piperidines; Potassium Channel Blockers; Pregnanolone; Rats; Rats, Sprague-Dawley; Seizures

Topics: Animals; Anxiety; Corticosterone; Disease Models, Animal; Female; Maternal Behavior; Pregnancy; Pregnanolone; Rats; Rats, Sprague-Dawley; Social Isolation; Weaning

Topics: Administration, Inhalation; Alcoholism; Animals; Cerebral Cortex; Disease Models, Animal; Ethanol; Female; Hippocampus; Male; Mice; Mice, Inbred DBA; Mice, Transgenic; Neurotransmitter Agents; Pregnanolone; Substance Withdrawal Syndrome

Topics: Amyotrophic Lateral Sclerosis; Animals; Brain-Derived Neurotrophic Factor; Choline O-Acetyltransferase; Disease Models, Animal; Female; Male; Mice; Motor Neurons; Nerve Degeneration; Neuroprotective Agents; Nitric Oxide Synthase; Pregnanolone; Progesterone; Receptor, trkB; Receptors, Nerve Growth Factor; Spinal Cord; Superoxide Dismutase

Topics: Animals; Brain; Desoxycorticosterone; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Male; Pregnanolone; Rats; Rats, Wistar

Topics: Animals; Antidepressive Agents; Depressive Disorder; Disease Models, Animal; Genetic Predisposition to Disease; Imipramine; Infusions, Intraventricular; Male; Motor Activity; Pregnanolone; Random Allocation; Rats, Wistar; Selective Breeding; Species Specificity

Topics: Animals; Brain; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Male; Mice, Inbred C57BL; Motor Activity; Multiple Sclerosis; Physical Conditioning, Animal; Pregnanolone; Running

Topics: Animals; Animals, Newborn; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Brain; Disease Models, Animal; GABA Modulators; Guinea Pigs; Locomotion; Male; Myelin Basic Protein; Neurosteroids; Pregnanolone; Premature Birth; Proof of Concept Study; Receptors, GABA-A; Social Behavior

Topics: 8,11,14-Eicosatrienoic Acid; Analgesics; Animals; Cerebral Hemorrhage; Disease Models, Animal; Gabapentin; Hyperalgesia; Male; Pregnanolone; Proof of Concept Study; Random Allocation; Rats, Sprague-Dawley; Receptors, GABA-A; Stroke; Thalamus

Topics: Androstanes; Animals; Autism Spectrum Disorder; Behavior, Animal; Benzazepines; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Grooming; Humans; Male; Mice; Prefrontal Cortex; Pregnanolone; Receptors, GABA-A; Treatment Outcome

Topics: Animals; Behavior, Animal; Brain; Dermatitis, Atopic; Diet; Disease Models, Animal; Eczema; Grooming; Male; Mice; Pregnanolone; Pruritus

Topics: Animals; Autism Spectrum Disorder; Behavior Observation Techniques; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Female; Male; Medicine, Kampo; Mice; Mice, Inbred ICR; Ovariectomy; Prefrontal Cortex; Pregnanolone; Receptors, Dopamine D1; Receptors, GABA-A; Sex Factors; Social Behavior; Treatment Outcome

Topics: Amides; Animals; Anxiety; Disease Models, Animal; Emotions; Ethanolamines; Fear; Hippocampus; Male; Mice; Palmitic Acids; PPAR alpha; Pregnanolone; Social Isolation; Stress Disorders, Post-Traumatic

Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Animals; Bicuculline; Corpus Callosum; Demyelinating Diseases; Disease Models, Animal; Female; Finasteride; GABA Antagonists; Lysophosphatidylcholines; Male; Microglia; Multiple Sclerosis; Myelin Proteins; Myelin Sheath; Nerve Tissue Proteins; Oligodendrocyte Precursor Cells; Oligodendroglia; Pregnancy; Pregnancy Complications; Pregnanolone; Puerperal Disorders; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Remyelination

Topics: Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Finasteride; Haloperidol; Housing, Animal; Male; Mice; Pregnanolone; Tics; Tourette Syndrome

Topics: 1-Deoxynojirimycin; 2-Hydroxypropyl-beta-cyclodextrin; Animals; Cell Separation; Disease Models, Animal; Flow Cytometry; Genotype; Lipid Metabolism; Mice; Niemann-Pick Disease, Type C; Pregnanolone; Spleen

Topics: Animals; Anti-Inflammatory Agents; Apocynaceae; Carrageenan; Cell Line; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Edema; Female; Glycosides; Granuloma; Hexosaminidases; Lipopolysaccharides; Macrophages; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Plants, Medicinal; Pregnanes; Pregnanolone; Rats

Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Animals, Newborn; Birth Weight; Brain; Disease Models, Animal; Female; Gestational Age; Glial Fibrillary Acidic Protein; Guinea Pigs; Hydrocortisone; Male; Microtubule-Associated Proteins; Myelin Basic Protein; Myelin Sheath; Neuroglia; Neurons; Pregnancy; Pregnanolone; Premature Birth; Progesterone; Steroids

Topics: Analgesia; Analgesics; Animals; Disease Models, Animal; Male; Mononeuropathies; Neuralgia; Oxazines; Pain Management; Pain Threshold; Pregnanolone; Rats; Rats, Sprague-Dawley; Spinal Cord

Topics: 1-Deoxynojirimycin; Animals; Cognition; Cyclodextrins; Disease Models, Animal; Drug Therapy, Combination; Mice; Mice, Knockout; Microscopy, Electron, Transmission; Motor Activity; Neuroprotective Agents; Niemann-Pick Disease, Type C; Pregnanolone

Topics: Animals; Brain Ischemia; Disease Models, Animal; Glutamates; Hippocampus; Male; Neuroprotective Agents; Pregnanolone; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

Topics: Age Factors; Anesthetics; Animals; Animals, Newborn; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Excitatory Amino Acid Agonists; Exploratory Behavior; Female; Humans; Infant; Male; N-Methylaspartate; Pregnanolone; Rats; Rats, Sprague-Dawley; Reaction Time; Social Behavior; Spasms, Infantile; Statistics, Nonparametric

Topics: Animals; Body Temperature Regulation; Disease Models, Animal; Infarction, Middle Cerebral Artery; Male; Motor Activity; Neuroprotective Agents; Postoperative Period; Pregnanolone; Progesterone; Rats; Rats, Inbred SHR; Temperature

Topics: 1-Deoxynojirimycin; Animals; Cell Count; Cerebellum; Cyclodextrins; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Enzyme Inhibitors; Mice; Nerve Degeneration; Neurons; Niemann-Pick Disease, Type C; Pregnanolone

Topics: 5-alpha Reductase Inhibitors; Animals; Axons; Disease Models, Animal; GABA Antagonists; Glaucoma; Hydrostatic Pressure; Male; Neuroprotective Agents; Neurotransmitter Agents; Pregnanolone; Rats; Rats, Sprague-Dawley; Retina; Retinal Ganglion Cells

Topics: Animals; Anticonvulsants; Cicer; Disease Models, Animal; Electroshock; Epilepsy; Male; Mice; Pentylenetetrazole; Plant Extracts; Pregnanolone; Rats; Rats, Wistar; Seeds; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Corpus Striatum; Disease Models, Animal; Dopaminergic Neurons; Doublecortin Protein; Lateral Ventricles; Male; Mesencephalon; Mice, Transgenic; Mutation; Neural Stem Cells; Neurogenesis; Nootropic Agents; Plaque, Amyloid; Pregnanolone; Presenilin-1; Tyrosine 3-Monooxygenase

Topics: Animals; Anticonvulsants; Bridged-Ring Compounds; Calcium; Cells, Cultured; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hippocampus; Male; Mice; Neuroimmunomodulation; Neurons; Pregnanolone; Seizures

Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Desoxycorticosterone; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; GABA Modulators; Male; Metyrapone; Motivation; Oxazepam; Pregnanolone; Rats, Wistar; Self Administration

Topics: Alzheimer Disease; Animals; Biomarkers; Brain; Bromodeoxyuridine; Cell Differentiation; Cyclic AMP Response Element-Binding Protein; Cyclodextrins; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Evaluation, Preclinical; Female; Humans; Male; Maximum Tolerated Dose; Mice, Inbred C57BL; Mice, Transgenic; Neurogenesis; No-Observed-Adverse-Effect Level; Phosphorylation; Pregnanolone; Proliferating Cell Nuclear Antigen; Rabbits; Rats, Sprague-Dawley; Treatment Outcome

Topics: Amygdala; Animals; Animals, Newborn; CHO Cells; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; Fragile X Mental Retardation Protein; Fragile X Syndrome; GABA Agents; GABA Modulators; gamma-Aminobutyric Acid; Heterocyclic Compounds, 2-Ring; In Vitro Techniques; Membrane Potentials; Mice; Mice, Knockout; Patch-Clamp Techniques; Pregnanolone; Receptors, GABA-A; Transfection

Topics: Animals; Anti-Anxiety Agents; Anxiety; Disease Models, Animal; Fear; Hippocampus; Isoquinolines; Male; Motor Activity; Prefrontal Cortex; Pregnanolone; Purines; Rats; Rats, Sprague-Dawley; Stress Disorders, Post-Traumatic

Topics: Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Anti-Inflammatory Agents; Aspartic Acid Endopeptidases; Brain-Derived Neurotrophic Factor; Cyclooxygenase 2; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalitis; Gene Expression Regulation; Hippocampus; Isoquinolines; Lipopolysaccharides; Male; Maze Learning; Mice; Mice, Inbred C57BL; Pregnanolone; Progesterone; Receptors, GABA

Topics: Adrenergic Agents; Analysis of Variance; Animals; Cognition Disorders; Disease Models, Animal; Escape Reaction; Exploratory Behavior; Male; Maze Learning; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Pregnanolone; Rats; Rats, Wistar; Reaction Time; Recognition, Psychology; Substantia Nigra

Topics: 17-Ketosteroids; Adrenal Glands; Amyotrophic Lateral Sclerosis; Androstanols; Animals; Brain; Corticosterone; Disease Models, Animal; Female; Gas Chromatography-Mass Spectrometry; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Male; Mice; Motor Neurons; Pregnanolone; Progesterone; Spinal Cord; Testis; Testosterone

Topics: 5-alpha Reductase Inhibitors; Animals; Carrier Proteins; Cholestenone 5 alpha-Reductase; Disease Models, Animal; Dutasteride; Glaucoma; In Vitro Techniques; Isoquinolines; Male; Pregnanolone; Pressure; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Retina; Retinal Ganglion Cells; Up-Regulation

Topics: Anesthetics; Animals; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Hypersensitivity; Male; Median Nerve; Medulla Oblongata; Neuroglia; Neurotransmitter Agents; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA

Topics: Acetylcholinesterase; Anesthetics; Animals; Antineoplastic Agents; Disease Models, Animal; Evoked Potentials, Motor; Male; Motor Disorders; Muscle Strength; Neural Conduction; Organoplatinum Compounds; Oxaliplatin; Pregnanolone; Psychomotor Performance; Rats; Rats, Sprague-Dawley

Topics: 1-Deoxynojirimycin; Animals; Behavior, Animal; Body Weight; Brain; Cognition; Cyclodextrins; Disease Models, Animal; Drug Administration Schedule; Drug Combinations; Hypolipidemic Agents; Male; Maze Learning; Mice; Mice, Inbred BALB C; Niemann-Pick Disease, Type C; Organ Size; Pregnanolone

Topics: Animals; Antidepressive Agents; Behavior, Animal; Carrier Proteins; Depression; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Hippocampus; Isoquinolines; Ligands; Male; Molecular Weight; Prefrontal Cortex; Pregnanolone; Purines; Rats, Sprague-Dawley; Receptors, GABA-A

Topics: Angelman Syndrome; Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Disease Models, Animal; Female; Hippocampus; Long-Term Potentiation; Male; Maze Learning; Memory, Short-Term; Mice, Knockout; Motor Activity; Pentylenetetrazole; Pregnanolone; Receptors, GABA-A; Seizures; Spatial Memory; Tissue Culture Techniques; Ubiquitin-Protein Ligases

Topics: Amygdala; Animals; Bridged-Ring Compounds; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Fear; Hippocampus; Male; Maze Learning; Paeonia; Prefrontal Cortex; Pregnanolone; Rats; Rats, Sprague-Dawley; Stress Disorders, Post-Traumatic

Topics: 5-alpha Reductase Inhibitors; Acoustic Stimulation; Animals; Antipsychotic Agents; Brain; Cholestenone 5 alpha-Reductase; Disease Models, Animal; Dose-Response Relationship, Drug; Finasteride; Gene Expression Regulation, Enzymologic; Male; Pregnanolone; Psychotic Disorders; Rats; Rats, Sprague-Dawley; Reflex, Startle; Sleep Deprivation; Steroids

Topics: 5-alpha Reductase Inhibitors; Animals; Animals, Newborn; Anxiety; Brain; Disease Models, Animal; Exploratory Behavior; Female; Finasteride; Guinea Pigs; Hydrocortisone; Nerve Tissue Proteins; Neurotransmitter Agents; Pregnancy; Pregnanolone; Prenatal Exposure Delayed Effects; Radioimmunoassay; Sex Factors; Statistics, Nonparametric

Topics: Alcohol Drinking; Alcoholism; Animals; Behavior, Animal; Cholestenone 5 alpha-Reductase; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Finasteride; Male; Mice; Mice, Inbred C57BL; Pregnanolone; Receptors, GABA-A; Time Factors

Topics: Aging; Animals; Animals, Genetically Modified; Brain; Brain Chemistry; Cerebral Cortex; Desoxycorticosterone; Disease Models, Animal; Down-Regulation; Epilepsy, Absence; gamma-Aminobutyric Acid; Male; Neuronal Plasticity; Pregnanolone; Protein Subunits; Rats; Rats, Wistar; Receptors, GABA-A; Steroids; Stress, Psychological; Synapses; Synaptic Transmission; Thalamus; Up-Regulation

Topics: Animals; Blood Coagulation; Brain Injuries; Disease Models, Animal; Factor XIII; Fibrinogen; Gene Expression Regulation; Hemostasis; Humans; Male; Neuropeptides; Neuroserpin; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serpins; Thrombin; Tissue Plasminogen Activator

Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Alcohol-Induced Disorders, Nervous System; Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epilepsy; Finasteride; Genetic Predisposition to Disease; Hippocampus; Mice; Mice, Transgenic; Neurons; Pentylenetetrazole; Pregnanolone; Substance Withdrawal Syndrome

Topics: Anesthetics; Animals; Astrocytes; Autophagy; Cholesterol; Disease Models, Animal; Encephalitis; Intracellular Signaling Peptides and Proteins; Lysosomes; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Microglia; Myelin Sheath; Neurons; Niemann-Pick C1 Protein; Niemann-Pick Disease, Type C; Pregnanolone; Proteins

Topics: Analysis of Variance; Anesthetics; Animals; Animals, Newborn; Disease Models, Animal; Female; Male; Maternal Behavior; Maze Learning; Mood Disorders; Pregnancy; Pregnanolone; Prenatal Exposure Delayed Effects; Rats; Sexual Behavior, Animal; Swimming; Vocalization, Animal

Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Behavior, Animal; Dehydroepiandrosterone Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Fluoxetine; Injections, Intraventricular; Male; Maze Learning; Mice; Motor Activity; Obsessive-Compulsive Disorder; Pregnanolone; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Social Isolation; Stress, Physiological

Topics: 1-Deoxynojirimycin; 2-Hydroxypropyl-beta-cyclodextrin; Animals; beta-Cyclodextrins; Cholesterol; Cyclodextrins; Disease Models, Animal; Disease Progression; Drug Synergism; Enzyme Inhibitors; Glycosphingolipids; Mice; Mice, Transgenic; Neurons; Niemann-Pick Disease, Type C; Pregnanolone; Treatment Outcome

Topics: 20-alpha-Dihydroprogesterone; Acute Disease; Androstane-3,17-diol; Animals; Brain; Chromatography, Liquid; Dihydrotestosterone; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Male; Mass Spectrometry; Multiple Sclerosis; Neurotransmitter Agents; Pregnanolone; Progesterone; Rats; Sex Characteristics; Testosterone

Topics: Animals; Convulsants; Disease Models, Animal; Electrophoresis, Agar Gel; Enzyme Inhibitors; Finasteride; Indomethacin; Male; Mice; Neurons; Picrotoxin; Pregnanolone; Seizures

Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Acute Disease; Alcohol-Induced Disorders, Nervous System; Animals; Castration; Central Nervous System Depressants; Desoxycorticosterone; Disease Models, Animal; Enzyme Inhibitors; Ethanol; Female; Finasteride; gamma-Aminobutyric Acid; Male; Mice; Neural Inhibition; Neurotransmitter Agents; Pregnanolone; Progesterone; Receptors, GABA-A; Substance Withdrawal Syndrome

Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Anesthetics; Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Conditioning, Operant; Disease Models, Animal; Extinction, Psychological; Female; Male; Pregnanolone; Rats; Rats, Wistar; Secondary Prevention; Self Administration; Sex Factors; Yohimbine

Topics: Animals; Antidepressive Agents; Benzazepines; Depression; Diestrus; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Estrus; Female; Pregnanolone; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Swimming

Topics: Aging; Animals; Anticonvulsants; Brain; Disease Models, Animal; Electric Stimulation; Epilepsy; Male; Motor Activity; Neuropsychological Tests; Pregnanolone; Rats; Rats, Wistar; Seizures; Time Factors

Topics: Amygdala; Animals; Anticonvulsants; Clonazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy, Temporal Lobe; Female; Kindling, Neurologic; Mice; Mice, Inbred C57BL; Pregnanolone; Seizures

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Proliferation; Disease Models, Animal; Humans; Learning; Male; Memory; Mice; Mice, Transgenic; Neurogenesis; Neurons; Pregnanolone; Stem Cells

Topics: Animals; Disease Models, Animal; Electroencephalography; Enzyme Inhibitors; Epilepsy; Female; Finasteride; Gonadotropins; Lithium; Neurotransmitter Agents; Pilocarpus; Pregnanolone; Rats

Topics: Aging; Animals; Behavior, Animal; Brain; Disease Models, Animal; Indomethacin; Male; Memory Disorders; Pregnanolone; Rats; Rats, Sprague-Dawley; Sleep Disorders, Circadian Rhythm; Steroids

Topics: 3-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Age Factors; Animals; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Epilepsy; Hippocampus; Immunoblotting; Male; Mice; Mice, Inbred Strains; Neurotransmitter Agents; Pregnanolone; Receptors, GABA-A

Topics: Amygdala; Animals; Antidepressive Agents; Avoidance Learning; CA3 Region, Hippocampal; Depression; Disease Models, Animal; Dizocilpine Maleate; Drug Combinations; Flumazenil; GABA Antagonists; Helplessness, Learned; Humans; Injections, Intraventricular; Male; Nucleus Accumbens; Prefrontal Cortex; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, N-Methyl-D-Aspartate

Topics: Action Potentials; Affinity Labels; Animals; Blotting, Western; Dentate Gyrus; Disease Models, Animal; Electric Stimulation; Electrophysiology; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Hippocampus; Immunoprecipitation; Male; Neural Inhibition; Neurons; Neurotransmitter Agents; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

Topics: Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Pregnanolone; Rats; Rats, Wistar; Self Administration; Sucrose; Yohimbine

Topics: Alcoholism; Animals; Cerebral Cortex; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ethanol; Male; Motor Activity; Pregnanolone; Pregnenolone; Rats; Rats, Inbred Strains; Self Administration

Topics: Alcohol Drinking; Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking; Electroshock; Emotions; Ethanol; Male; Maze Learning; Pregnanolone; Rats; Rats, Sprague-Dawley; Social Isolation; Stress, Psychological

Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Anesthetics; Animals; Disease Models, Animal; Electric Stimulation; Exploratory Behavior; Ganglia, Spinal; Gene Expression Regulation; Hyperalgesia; Male; Nerve Fibers; Neural Conduction; Neuralgia; Neurofilament Proteins; Organoplatinum Compounds; Oxaliplatin; Pain Threshold; Pregnanolone; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Statistics, Nonparametric; Time Factors

Topics: Animals; Brain Ischemia; Cognition; Disease Models, Animal; Male; Maze Learning; Memory Disorders; Neuroprotective Agents; Pregnanolone; Progesterone; Random Allocation; Rats; Rats, Sprague-Dawley; Swimming; Time Factors; Treatment Outcome

Topics: Animals; Anxiety; Avoidance Learning; Body Weight; CA1 Region, Hippocampal; Disease Models, Animal; Exploratory Behavior; Male; Maze Learning; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Statistics, Nonparametric

Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Bicuculline; Brain; Brain Injuries; Disease Models, Animal; Drug Administration Routes; Functional Laterality; GABA-A Receptor Antagonists; Hypoxia-Ischemia, Brain; Pregnanolone; Progesterone; Rats; Rats, Wistar; Time Factors

Topics: Animals; Brain; Central Nervous System Stimulants; Disease Models, Animal; Hyperalgesia; Ligation; Male; Neuralgia; Pain Threshold; Paroxetine; Pregnanolone; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Spinal Cord

Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); Analysis of Variance; Animals; Avoidance Learning; Disease Models, Animal; Drug Administration Schedule; Estradiol; Exploratory Behavior; Female; Gene Expression Regulation, Enzymologic; Hippocampus; Inhibition, Psychological; Memory Disorders; Motor Activity; Ovariectomy; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; RNA, Messenger

Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Analysis of Variance; Anesthetics; Animals; Bromodeoxyuridine; Cell Count; Disease Models, Animal; Dopaminergic Neurons; Humans; Mice; Mice, Transgenic; Mutation; Pregnanolone; Presenilin-1; Substantia Nigra; tau Proteins; Tyrosine 3-Monooxygenase

Topics: Analgesics; Animals; Disease Models, Animal; Gelsemium; Hyperalgesia; Indole Alkaloids; Inflammation; Male; Mice; Mice, Inbred ICR; Neuralgia; Pain; Pain Measurement; Pregnanolone; Rats; Rats, Sprague-Dawley; Spinal Cord; Up-Regulation

Topics: 5-alpha Reductase Inhibitors; Animals; Diazepam; Disease Models, Animal; Epilepsy; Female; Finasteride; Gonadotropins; Hippocampus; Kindling, Neurologic; Menstrual Cycle; Mice; Mice, Inbred C57BL; Pregnanolone; Progesterone; Rats; Real-Time Polymerase Chain Reaction; Receptors, GABA-A; RNA, Messenger; Substance Withdrawal Syndrome

Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antipsychotic Agents; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Hippocampus; Humans; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Pregnanolone; Presenilin-1; Statistics, Nonparametric; Time Factors

Topics: Animals; Anxiety; Avoidance Learning; Cognition Disorders; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Male; Motor Activity; Pregnanolone; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Vocalization, Animal

Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Anesthetics; Animals; Disease Models, Animal; Drug Administration Schedule; Female; Hippocampus; Humans; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Mutation; Pregnanolone; Presenilin-1; Sex Factors; Time Factors

Topics: Animals; Disease Models, Animal; Dopamine; Male; Mesencephalon; Mice; MPTP Poisoning; Neurons; Norepinephrine; Pregnanolone; Psychomotor Performance; Substantia Nigra; Tyrosine 3-Monooxygenase

Topics: Animals; Animals, Newborn; Bacterial Infections; Brain; Disease Models, Animal; Humans; Hydrocortisone; Infant; Lipopolysaccharides; Pregnanolone; Pregnenolone; Progesterone; Risk Factors; Sheep; Sleep; Sudden Infant Death

Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Binding, Competitive; Cerebral Cortex; Dehydroepiandrosterone; Disease Models, Animal; Female; Maze Learning; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A; Severity of Illness Index; Swimming

Topics: Animals; Brain; Depression; Disease Models, Animal; Olfactory Bulb; Organ Specificity; Pregnanolone; Rats; Rats, Sprague-Dawley; Time Factors

Topics: Animals; Anticonvulsants; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Female; Finasteride; Kindling, Neurologic; Male; Mice; Mice, Knockout; Mutation; Pregnanolone; Progesterone; Receptors, Progesterone; Seizures; Steroids

Topics: Animals; Anticonvulsants; Dentate Gyrus; Diazepam; Disease Models, Animal; Electric Conductivity; Epilepsy, Temporal Lobe; Flumazenil; GABA Modulators; Lithium; Male; Neural Inhibition; Patch-Clamp Techniques; Pilocarpine; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Status Epilepticus; Synapses

Topics: Analysis of Variance; Anesthetics; Animals; Basal Nucleus of Meynert; Behavior, Animal; Brain Injuries; Cell Count; Choline O-Acetyltransferase; Disease Models, Animal; Drug Administration Schedule; Immunohistochemistry; Male; Maze Learning; Mediodorsal Thalamic Nucleus; Motor Activity; Pregnanolone; Rats; Rats, Sprague-Dawley; Reaction Time; Regeneration; Spatial Behavior; Time Factors

Topics: Animals; Anticonvulsants; Clonazepam; Cornea; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Epilepsies, Partial; GABA Modulators; Humans; Male; Mice; Pregnanolone; Receptors, GABA; Seizures; Steroids

Topics: Animals; Brain Edema; Brain Injuries; Cytokines; Disease Models, Animal; Down-Regulation; Drug Administration Schedule; Encephalitis; Gene Expression; Interleukin-1; Male; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Reaction Time; RNA, Messenger; Treatment Outcome; Tumor Necrosis Factor-alpha

Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Animals; Anxiety; Behavior, Animal; Disease Models, Animal; Enzyme Inhibitors; Female; Finasteride; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Knockout; Pregnanolone; Premenstrual Syndrome; Receptors, GABA-A

Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Age Factors; Anesthetics; Animals; Anisotropy; Antigens, Differentiation; Body Weight; Brain; Cell Count; Cell Survival; Demyelinating Diseases; Disease Models, Animal; Drug Administration Schedule; Glial Fibrillary Acidic Protein; Immunohistochemistry; Magnetic Resonance Imaging; Membrane Transport Proteins; Mice; Mice, Inbred BALB C; Mice, Knockout; Motor Activity; Niemann-Pick Diseases; Pregnanolone; Time Factors

Topics: Animals; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Fibrinolytic Agents; Male; Pregnanolone; Rabbits; Receptors, N-Methyl-D-Aspartate; Time Factors; Tissue Plasminogen Activator; Treatment Outcome

Topics: Age Factors; Animals; Animals, Newborn; Anticonvulsants; Desoxycorticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Electroencephalography; Pregnanolone; Rats; Seizures

Topics: Analysis of Variance; Animals; Autopsy; Brain; Cerebrovascular Circulation; Data Interpretation, Statistical; Disease Models, Animal; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Injections, Subcutaneous; Laser-Doppler Flowmetry; Male; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors

Topics: Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Electroencephalography; Epilepsy, Absence; Male; Microinjections; Pregnanolone; Pregnenolone; Rats; Rats, Inbred Strains; Time Factors

Topics: Age Factors; Anesthetics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Subcutaneous; Male; Motor Activity; Pentylenetetrazole; Pregnanolone; Rats; Rats, Wistar; Seizures

Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Alcohol-Induced Disorders, Nervous System; Alcoholism; Animals; Brain; Central Nervous System Depressants; Conditioning, Psychological; Disease Models, Animal; Drug Interactions; Enzyme Inhibitors; Ethanol; Finasteride; Male; Mice; Mice, Inbred DBA; Motor Activity; Pregnanolone; Progesterone; Proto-Oncogene Proteins c-fos; Reward; Ventral Tegmental Area

Topics: Amygdala; Animals; Anticonvulsants; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Kindling, Neurologic; Locomotion; Male; Pregnanolone; Progesterone; Rats; Rats, Wistar; Seizures; Severity of Illness Index; Time Factors

Topics: Anesthetics; Animals; Behavior, Animal; Blotting, Western; Brain Injuries; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Drug Administration Schedule; Glial Fibrillary Acidic Protein; HSP70 Heat-Shock Proteins; Immunohistochemistry; Male; Motor Activity; Peptides, Cyclic; Perceptual Disorders; Pregnanolone; Random Allocation; Rats; Rats, Sprague-Dawley; Recovery of Function; Substance Withdrawal Syndrome; Time Factors; Tumor Suppressor Protein p53; Upper Extremity

Topics: Animals; Cerebellum; Disease Models, Animal; GABA-A Receptor Agonists; Gene Expression; Hydrocarbons, Fluorinated; Intracellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Microglia; Mutation; Neuroprotective Agents; Niemann-Pick C1 Protein; Niemann-Pick Diseases; Pregnane X Receptor; Pregnanolone; Proteins; Purkinje Cells; Receptors, Steroid; Stereoisomerism; Sulfonamides

Topics: Amygdala; Animals; Anticonvulsants; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Female; Kindling, Neurologic; Pregnanolone; Rats; Rats, Wistar; Seizures; Severity of Illness Index; Time Factors

Topics: Animals; Animals, Genetically Modified; Cricetinae; Dehydroepiandrosterone; Desoxycorticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Injections, Intraperitoneal; Male; Mesocricetus; Pregnanolone; Pregnenolone

Topics: Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Disease Models, Animal; Fear; Hippocampus; Injections, Intraventricular; Maze Learning; Microinjections; Prefrontal Cortex; Pregnanolone; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

Topics: Adrenalectomy; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Enzyme Inhibitors; GABA Agonists; GABA Antagonists; Male; Maze Learning; Muscimol; Oxazines; Pregnanolone; Rats; Rats, Sprague-Dawley; Reaction Time

Topics: Animals; Antipsychotic Agents; Brain Diseases; Control Groups; Disease Models, Animal; Dopamine; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Haloperidol; Male; Movement Disorders; Neuroprotective Agents; Oxidative Stress; Pregnanolone; Progesterone; Rats; Rats, Inbred ACI; Receptors, GABA-A

Topics: Age Factors; Alzheimer Disease; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Brain; Cognition; Disease Models, Animal; Exploratory Behavior; Female; Heterozygote; Hippocampus; Maze Learning; Mice; Mice, Mutant Strains; Mice, Transgenic; Motor Activity; Pregnanolone; Presenilin-1; Progesterone; Random Allocation; Recognition, Psychology; Statistics, Nonparametric

Topics: Animals; Benzodiazepines; Disease Models, Animal; Drug Resistance; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippocampus; Male; Neural Inhibition; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Steroids; Synapses; Synaptic Transmission

Topics: Animals; Animals, Genetically Modified; Axons; Charcot-Marie-Tooth Disease; Chromatography, Liquid; Disease Models, Animal; Down-Regulation; Female; gamma-Aminobutyric Acid; Male; Mass Spectrometry; Mutation; Myelin Proteins; Peripheral Nerves; Pregnanolone; Rats; Receptors, GABA-A; Sciatic Nerve; Sex Characteristics; Steroids

Topics: Analysis of Variance; Anesthetics; Animals; Body Temperature; Central Nervous System Depressants; Desoxycorticosterone; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Interactions; Drug Tolerance; Ethanol; Hypothermia; Male; Mice; Motor Activity; Pregnanolone; Pregnenolone

Topics: Animals; Antidepressive Agents; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Hippocampus; Male; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A; RNA, Messenger; Swimming

Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Animals; Anti-Anxiety Agents; Antipsychotic Agents; Anxiety Disorders; Benzodiazepines; Brain; Disease Models, Animal; Drug Administration Schedule; Drug Interactions; Enzyme Inhibitors; Finasteride; gamma-Aminobutyric Acid; Male; Maze Learning; Olanzapine; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Restraint, Physical; Stress, Psychological

Topics: Animals; Anti-Anxiety Agents; Cerebral Cortex; Disease Models, Animal; Drug Synergism; Electroencephalography; Epilepsies, Partial; gamma-Aminobutyric Acid; Male; Neurons; Pregnanolone; Rats; Rats, Wistar; Substance Withdrawal Syndrome

Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Diazepam; Disease Models, Animal; Electroshock; Estradiol; Female; Indomethacin; Pregnanolone; Premenstrual Syndrome; Progesterone; Rats; Substance Withdrawal Syndrome

Topics: Affinity Labels; Animals; Anti-Anxiety Agents; Anxiety; Azides; Behavior, Animal; Benzodiazepines; Binding Sites; Chloride Channels; Conflict, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Organophosphorus Compounds; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A

Topics: Animals; Anticonvulsants; Disease Models, Animal; Electric Stimulation; Electrodes, Implanted; Epilepsy; Female; Kainic Acid; Ovariectomy; Perforant Pathway; Pregnanolone; Progesterone; Rats; Rats, Long-Evans

Topics: Age Factors; Animals; Animals, Newborn; Anticonvulsants; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy, Tonic-Clonic; Flurothyl; Male; Motor Activity; Pregnanolone; Rats; Rats, Sprague-Dawley; Seizures

Topics: Animals; Anticonvulsants; Convulsants; Diazepam; Disease Models, Animal; Enzyme Inhibitors; Epilepsy; Female; Finasteride; Menstruation; Oxidoreductases; Pentylenetetrazole; Pregnanolone; Pseudopregnancy; Rats; Rats, Sprague-Dawley; Seizures; Steroids; Valproic Acid

Topics: Animals; Anti-Anxiety Agents; Anxiety; Chlordiazepoxide; Disease Models, Animal; Electric Stimulation; GABA Modulators; Male; Maze Learning; Pregnanolone; Progesterone; Rats; Rats, Long-Evans; Receptors, GABA-A

Topics: Allosteric Regulation; Animals; Anticonvulsants; Benzodiazepinones; Desoxycorticosterone; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Female; Menstrual Cycle; Pentylenetetrazole; Phenobarbital; Pregnanolone; Pseudopregnancy; Rats; Rats, Sprague-Dawley; Receptors, GABA; Steroids; Substance Withdrawal Syndrome; Valproic Acid

Topics: 20-alpha-Dihydroprogesterone; Adult; Animals; Behavior, Animal; Disease Models, Animal; Disease Susceptibility; Epilepsy; Female; Finasteride; Gonadotropins, Equine; Humans; Menstrual Cycle; Pentylenetetrazole; Pregnanolone; Progesterone; Pseudopregnancy; Rats; Rats, Sprague-Dawley; Receptors, GABA; Steroids; Substance Withdrawal Syndrome

Topics: Animals; Anticonvulsants; Disease Models, Animal; Dopamine; Drug Combinations; Drug Tolerance; Male; Mice; Midazolam; Muscle, Skeletal; Picrotoxin; Pregnanolone; Receptors, GABA-A; Seizures

Topics: Analgesics; Animals; Disease Models, Animal; Injections, Spinal; Male; Morphine; Pain; Pregnanolone; Rats; Spinal Cord