Page last updated: 2024-08-23

pregnanolone and Depressive Disorder

pregnanolone has been researched along with Depressive Disorder in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (22.22)18.2507
2000's1 (11.11)29.6817
2010's4 (44.44)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Deligiannidis, KM; Dubuke, ML; Kroll-Desrosiers, AR; Shaffer, SA; Tan, Y1
Cooke, E; Leader, LD; VandenBerg, A; Walkery, A1
Almeida, FB; Barros, HMT; Fonseca, AR; Heidrich, N; Nin, MS1
Cubero-Millán, I; Justicia-Martínez, F; León, J; Luna-Del-Castillo, JD; Machado-Casas, I; Molina-Carballo, A; Moreno-García, L; Moreno-Madrid, F; Muñoz-Hoyos, A; Uberos, J1
Ben Dor, R; Marx, CE; Rubinow, DR; Schmidt, PJ; Shampine, LJ1
Pearlstein, T1
Girdler, SS; Klatzkin, RR; Light, KC; Morrow, AL; Pedersen, CA1
di Michele, F; Hermann, B; Holsboer, F; Pasini, A; Romeo, E; Rupprecht, R; Spalletta, G; Ströhle, A1
Costa, E; Guidotti, A1

Reviews

3 review(s) available for pregnanolone and Depressive Disorder

ArticleYear
Review of Allopregnanolone Agonist Therapy for the Treatment of Depressive Disorders.
    Drug design, development and therapy, 2021, Volume: 15

    Topics: Antidepressive Agents; beta-Cyclodextrins; Bipolar Disorder; Depression, Postpartum; Depressive Disorder; Drug Combinations; Female; Humans; Pregnancy; Pregnanes; Pregnanolone; Psychiatric Status Rating Scales; Pyrazoles

2021
Premenstrual dysphoric disorder: out of the appendix.
    Archives of women's mental health, 2010, Volume: 13, Issue:1

    Topics: Anxiety Disorders; Depressive Disorder; Diagnostic and Statistical Manual of Mental Disorders; Estrogens; Female; Humans; Pregnanolone; Premenstrual Syndrome; Progesterone; Receptors, GABA-A; Serotonin

2010
Can the antidysphoric and anxiolytic profiles of selective serotonin reuptake inhibitors be related to their ability to increase brain 3 alpha, 5 alpha-tetrahydroprogesterone (allopregnanolone) availability?
    Biological psychiatry, 1998, Nov-01, Volume: 44, Issue:9

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Anxiety Disorders; Depressive Disorder; Humans; Pregnanolone; Rats; Receptors, GABA-A; Selective Serotonin Reuptake Inhibitors; Serotonin

1998

Trials

3 trial(s) available for pregnanolone and Depressive Disorder

ArticleYear
DHEA metabolism to the neurosteroid androsterone: a possible mechanism of DHEA's antidepressant action.
    Psychopharmacology, 2015, Volume: 232, Issue:18

    Topics: Androsterone; Antidepressive Agents; Cross-Over Studies; Dehydroepiandrosterone; Depressive Disorder; Depressive Disorder, Major; Female; Humans; Male; Middle Aged; Neurotransmitter Agents; Pregnanolone; Pregnenolone; Sex Factors; Treatment Outcome

2015
Associations of histories of depression and PMDD diagnosis with allopregnanolone concentrations following the oral administration of micronized progesterone.
    Psychoneuroendocrinology, 2006, Volume: 31, Issue:10

    Topics: Administration, Oral; Adult; Affect; Capsules; Cross-Over Studies; Depressive Disorder; Double-Blind Method; Female; Humans; Placebos; Pregnanolone; Premenstrual Syndrome; Progesterone; Time Factors

2006
Effects of antidepressant treatment on neuroactive steroids in major depression.
    The American journal of psychiatry, 1998, Volume: 155, Issue:7

    Topics: Adult; Ambulatory Care; Antidepressive Agents; Dehydroepiandrosterone; Depressive Disorder; Female; Fluoxetine; Follow-Up Studies; Hospitalization; Humans; Male; Middle Aged; Pregnanolone; Pregnenolone; Progesterone; Receptors, GABA; Steroids; Treatment Outcome

1998

Other Studies

3 other study(ies) available for pregnanolone and Depressive Disorder

ArticleYear
Longitudinal proneuroactive and neuroactive steroid profiles in medication-free women with, without and at-risk for perinatal depression: A liquid chromatography-tandem mass spectrometry analysis.
    Psychoneuroendocrinology, 2020, Volume: 121

    Topics: 20-alpha-Dihydroprogesterone; Adult; Anxiety; Chromatography, Liquid; Depression; Depression, Postpartum; Depressive Disorder; Desoxycorticosterone; Female; Humans; Longitudinal Studies; Neurosteroids; Parturition; Pregnancy; Pregnanolone; Pregnenolone; Prenatal Care; Progesterone; Prospective Studies; Risk Factors; Tandem Mass Spectrometry

2020
The effect of intracerebroventricular allopregnanolone on depressive-like behaviors of rats selectively bred for high and low immobility in the forced swim test.
    Physiology & behavior, 2018, 10-01, Volume: 194

    Topics: Animals; Antidepressive Agents; Depressive Disorder; Disease Models, Animal; Genetic Predisposition to Disease; Imipramine; Infusions, Intraventricular; Male; Motor Activity; Pregnanolone; Random Allocation; Rats, Wistar; Selective Breeding; Species Specificity

2018
Differential responses of two related neurosteroids to methylphenidate based on ADHD subtype and the presence of depressive symptomatology.
    Psychopharmacology, 2014, Volume: 231, Issue:17

    Topics: Adolescent; Attention; Attention Deficit Disorder with Hyperactivity; Biomarkers; Central Nervous System Stimulants; Child; Child, Preschool; Dehydroepiandrosterone; Depressive Disorder; Diagnostic and Statistical Manual of Mental Disorders; Female; Humans; Male; Methylphenidate; Neurotransmitter Agents; Pregnanolone

2014