Page last updated: 2024-08-23

pregnanolone and Depression, Postpartum

pregnanolone has been researched along with Depression, Postpartum in 70 studies

Research

Studies (70)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (2.86)	29.6817
2010's	35 (50.00)	24.3611
2020's	33 (47.14)	2.80

Authors

Authors	Studies
Betz, JF; Hantsoo, L; Osborne, LM; Payne, JL; Standeven, LR; Voegtline, K; Yenokyan, G	1
Balan, I; Boero, G; Morrow, AL	1
Castro-Zavala, A; Ferreres-Álvarez, I; Gallego-Landin, I; García-Baos, A; Martín-Sánchez, A; Puig-Reyne, X; Valverde, O	1
Battle, CL; Diaz, Z; Howard, MM	1
Adamičková, A; Gažová, A; Hrubá, O; Massarová, P; Vranecová, K; Žigová, L	1
Chen, J; Hu, L; Peng, H; Yang, K; Zeng, X; Zhu, W	1
Brunner, LM; Kufner, M; Nothdurfter, C; Pradhan, AK; Puig, X; Rammes, G; Rupprecht, C; Rupprecht, R; Schwarzbach, J; Wein, S	1
Goldman, D; Mazzu, MA; Meltzer-Brody, S; Rubinow, DR; Rudzinskas, SA; Schiller, CE; Schmidt, PJ	1
Estes, E; Mbilinyi, RH; Reddy, DS	1
Carlini, SV; Deligiannidis, KM; Osborne, LM	1
Heo, YA	1
Feng, S; Guo, K; Mao, M; Wang, X; Xu, S; Zhang, S; Zhao, L	1
Fantasia, HC	1
Garland, S; Piszczatoski, C; Powell, JG; Preston, K	1
Leader, LD; O'Connell, M; VandenBerg, A	1
Bale, TL; Cole, AB; Morrison, KE; Thompson, SM	1
Cooper, MC; Eldar-Lissai, A; Hodgkins, P; Kilvert, HS; Roskell, NS	1
Cristea, IA; Naudet, F	1
Barron, RJ; Jarman, AF; MacLean, JV; McGregor, AJ; Wightman, RS	1
Cieri-Hutcherson, NE; Gosciak, MF; Hutcherson, TC	1
Bond, JC; Chertavian, E; Cohen, JT; Eldar-Lissai, A; Gerbasi, ME; Hodgkins, P; Johnson, SJ; Meltzer-Brody, S	1
Jawaid, H; Khan, KS; Shabbir, O	1
Burval, J; Kerns, R; Reed, K	1
Gao, ML; Guo, H; Guo, WZ; Li, YF; Liu, YZ; Ma, L; Ma, YQ; Ren, P; Sun, L; Wang, JY	1
Amodeo, G; Beccarini Crescenzi, B; Bolognesi, S; Cuomo, A; Fagiolini, A; Goracci, A; Laurenzi, PF; Neal, SM; Rossi, R; Santucci, A	1
Acaster, S; Bonthapally, V; Eldar-Lissai, A; Fridman, M; Gerbasi, ME; Hodgkins, P; Kanes, SJ; Meltzer-Brody, S	2
Kroska, EB; Stowe, ZN	1
Deligiannidis, KM; Dubuke, ML; Kroll-Desrosiers, AR; Shaffer, SA; Tan, Y	1
Nguyen, DR; Patatanian, E	1
Payne, JL	1
Ackerman, MG; Blakemore, JK; Jacobson, MH; Kannan, K; Liu, M; Long, SE; Pinna, G; Romay-Tallon, R; Stein, CR; Trasande, L; Zhu, H	1
Ito, S; Rosen-Carole, C	1
Cornett, EM; Kaye, AD; Kaye, AM; Labbé, AM; Perkins, W; Rando, L; Urits, I; Viswanath, O	1
Cooke, E; Leader, LD; VandenBerg, A; Walkery, A	1
Colquhoun, H; Doherty, J; Hoffmann, E; Kanes, SJ; Meltzer-Brody, S; Raines, S; Rubinow, DR	1
Arnold, R; Colquhoun, H; Deligiannidis, KM; Doherty, J; Epperson, CN; Gunduz-Bruce, H; Hoffmann, E; Jonas, J; Kanes, S; Meltzer-Brody, S; Paul, S; Raines, S; Riesenberg, R; Rubinow, D; Schacterle, A	1
Comasco, E; Hellgren, C; Skalkidou, A; Sundström-Poromaa, I	1
Ackley, MA; Althaus, AL; Bai, Z; Belfort, GM; Beresis, RT; Blanco, MJ; Dai, J; Doherty, JJ; Grossman, SJ; Harrison, BL; Hoffmann, E; Loya, CM; Martinez Botella, G; Robichaud, AJ; Salituro, FG	1
Guintivano, J; Manuck, T; Meltzer-Brody, S	1
Burke, CS; Hermann, AD; Susser, LC	1
McEvoy, K; Osborne, LM; Payne, JL	1
Clemson, C; Colquhoun, H; Deligiannidis, KM; Epperson, CN; Jonas, J; Kanes, S; Li, H; Meltzer-Brody, S; Riesenberg, R; Rubinow, DR; Sankoh, AJ; Schacterle, A	1
Deligiannidis, KM; Edden, RA; Fales, CL; Frederick, BB; Hall, JE; Kroll-Desrosiers, AR; Moore, CM; Rothschild, AJ; Shaffer, SA; Sikoglu, EM; Tan, Y; Villamarin, V	1
Mody, I	1
Deligiannidis, KM; Fersh, M; Frieder, A; Hainline, R	1
Scott, LJ	1
Gordon, JA	1
Ciolino, JD; Stika, CS; Wisner, KL	1
Tufts, JA	1
Colquhoun, H; Doherty, J; Kanes, S; Meltzer-Brody, S; Rubinow, DR	1
Parekh, J; Tang, GY	1
Lüscher, B; Möhler, H	1
Naguy, A	1
Cai, DB; Ning, YP; Peng, XJ; Sim, K; Ungvari, GS; Wang, G; Xiang, YT; Zheng, W	1
Deligiannidis, KM; Frederick, B; Kopoyan, A; Kosma, CA; Moore, CM; Rothschild, AJ; Shaffer, SA; Sikoglu, EM; Svenson, AE	1
Åkerud, H; Bäckström, T; Hellgren, C; Skalkidou, A; Sundström-Poromaa, I	1
Rubinow, DR; Schiller, CE; Schmidt, PJ	1
Meltzer-Brody, S; Rubinow, DR; Schiller, CE	1
Beckmann, MW; Binder, EB; Braier, A; Brown, T; Clive, M; Cox, O; Fasching, PA; Gispen, F; Goes, F; Guintivano, J; Judy, J; Kaminsky, Z; Kimmel, M; Kornhuber, J; Meilman, S; Osborne, L; Payne, JL	1
Beckmann, MW; Binder, E; Brown, T; Clive, M; Cox, O; Fasching, PA; Gispen, F; Guintivano, J; Kaminsky, Z; Kimmel, M; Kornhuber, J; Osborne, LM; Payne, JL	1
Barton, BA; Deligiannidis, KM; Hall, JE; Jaitly, N; Kroll-Desrosiers, AR; Mo, S; Nguyen, HP; Rothschild, AJ; Shaffer, SA; Svenson, A	1
Gispen, F; Meilman, S; Osborne, LM; Payne, JL; Sanyal, A; Yenokyan, G	1
Gilbert Evans, SE; Purdy, RH; Romach, MK; Ross, LE; Sellers, EM	1
Farina, C; Genazzani, AR; Luisi, S; Nappi, RE; Petraglia, F; Polatti, F	1

Reviews

23 review(s) available for pregnanolone and Depression, Postpartum

Article	Year
Neurosteroids and translocator protein 18 kDa (TSPO) in depression: implications for synaptic plasticity, cognition, and treatment options. European archives of psychiatry and clinical neuroscience, 2023, Volume: 273, Issue:7 Topics: Anti-Anxiety Agents; Benzodiazepines; Carrier Proteins; Cognition; Depression; Depression, Postpartum; Depressive Disorder, Major; Female; gamma-Aminobutyric Acid; Humans; Ligands; Neuronal Plasticity; Neurosteroids; Neurotransmitter Agents; Pregnanolone; Receptors, GABA; Receptors, GABA-A	2023
Preclinical and clinical pharmacology of brexanolone (allopregnanolone) for postpartum depression: a landmark journey from concept to clinic in neurosteroid replacement therapy. Psychopharmacology, 2023, Volume: 240, Issue:9 Topics: Antidepressive Agents; Depression, Postpartum; Female; Humans; Neurosteroids; Pregnanolone; Receptors, GABA-A	2023
Current pharmacotherapy approaches and novel GABAergic antidepressant development in postpartum depression. Dialogues in clinical neuroscience, 2023, Volume: 25, Issue:1 Topics: Antidepressive Agents; Depression, Postpartum; Female; Humans; Pregnanolone; Psychotherapy	2023
Zuranolone: First Approval. Drugs, 2023, Volume: 83, Issue:16 Topics: Adult; Depression, Postpartum; Female; Humans; Pregnanes; Pregnanolone; Pyrazoles	2023
Research Trends and Hot Spots of Allopregnanolone Research in the Last 20 Years: A Bibliometric Analysis. Drug design, development and therapy, 2023, Volume: 17 Topics: Bibliometrics; Central Nervous System; Databases, Factual; Depression, Postpartum; Female; Humans; Nervous System Diseases; Pregnanolone	2023
Brexanolone (Zulresso): Finally, an FDA-Approved Treatment for Postpartum Depression. The Annals of pharmacotherapy, 2020, Volume: 54, Issue:2 Topics: Antidepressive Agents; beta-Cyclodextrins; Clinical Trials as Topic; Depression, Postpartum; Drug Combinations; Female; Humans; Infusions, Intravenous; Pregnanolone; Quality of Life; Severity of Illness Index; Treatment Outcome; United States; United States Food and Drug Administration	2020
Brexanolone for Postpartum Depression: Clinical Evidence and Practical Considerations. Pharmacotherapy, 2019, Volume: 39, Issue:11 Topics: Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; GABA Modulators; Humans; Pregnancy; Pregnanolone; Psychiatric Status Rating Scales; Severity of Illness Index	2019
Brexanolone for postpartum depression. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2020, Feb-19, Volume: 77, Issue:5 Topics: Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Pregnancy; Pregnanolone; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Risk Evaluation and Mitigation; Severity of Illness Index	2020
Advances in treatment for postpartum major depressive disorder. Expert opinion on pharmacotherapy, 2020, Volume: 21, Issue:14 Topics: Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Depressive Disorder, Major; Drug Combinations; Drug Monitoring; Estrogens; Female; Humans; Oxytocin; Pregnanolone; Randomized Controlled Trials as Topic; Transcranial Magnetic Stimulation; Treatment Outcome; United States	2020
Postpartum Depression: Identification and Treatment in the Clinic Setting. Obstetrics and gynecology clinics of North America, 2020, Volume: 47, Issue:3 Topics: Adult; Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Infant; Mass Screening; Neurosteroids; Perinatal Care; Postpartum Period; Pregnancy; Pregnanolone; Prevalence; Psychiatric Status Rating Scales; Psychotherapy; Risk Factors; Selective Serotonin Reuptake Inhibitors; Surveys and Questionnaires	2020
Brexanolone in Postpartum Depression: Journal of women's health (2002), 2021, Volume: 30, Issue:3 Topics: Adult; beta-Cyclodextrins; Clinical Decision-Making; Depression, Postpartum; Drug Combinations; Female; Humans; Pregnanolone; Treatment Outcome	2021
Brexanolone: A Novel Drug for the Treatment of Postpartum Depression. Journal of pharmacy practice, 2022, Volume: 35, Issue:3 Topics: beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Pregnancy; Pregnanolone; Unconsciousness	2022
Brexanolone to Treat Postpartum Depression in Adult Women. Psychopharmacology bulletin, 2021, 03-16, Volume: 51, Issue:2 Topics: Adult; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Pregnanolone	2021
Review of Allopregnanolone Agonist Therapy for the Treatment of Depressive Disorders. Drug design, development and therapy, 2021, Volume: 15 Topics: Antidepressive Agents; beta-Cyclodextrins; Bipolar Disorder; Depression, Postpartum; Depressive Disorder; Drug Combinations; Female; Humans; Pregnancy; Pregnanes; Pregnanolone; Psychiatric Status Rating Scales; Pyrazoles	2021
Predictors of Postpartum Depression: A Comprehensive Review of the Last Decade of Evidence. Clinical obstetrics and gynecology, 2018, Volume: 61, Issue:3 Topics: beta-Endorphin; Biomarkers; C-Reactive Protein; Corticotropin-Releasing Hormone; Depression, Postpartum; Epigenesis, Genetic; Female; Genetic Predisposition to Disease; Humans; Hydrocortisone; Interleukin-6; Life Change Events; Maternal Age; Mental Disorders; Oxytocin; Pregnancy; Pregnanolone; Premature Birth; Race Factors; Risk Factors; Social Class; Thyroid Function Tests	2018
GABA Archives of women's mental health, 2019, Volume: 22, Issue:1 Topics: Depression; Depression, Postpartum; Female; Humans; Menstruation; Mood Disorders; Postpartum Period; Pregnanolone; Receptors, GABA; Weaning	2019
Neuroactive Steroids and Perinatal Depression: a Review of Recent Literature. Current psychiatry reports, 2018, 08-09, Volume: 20, Issue:9 Topics: Depression; Depression, Postpartum; Female; Humans; Pregnancy; Pregnancy Complications; Pregnanolone	2018
Pharmacotherapy of Postpartum Depression: Current Approaches and Novel Drug Development. CNS drugs, 2019, Volume: 33, Issue:3 Topics: Animals; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Drug Development; Female; GABA Modulators; Humans; Neurosteroids; Pregnanes; Pregnanolone; Pyrazoles; Randomized Controlled Trials as Topic; United States; United States Food and Drug Administration	2019
From Neurobiology to Novel Medications: A Principled Approach to Translation. The American journal of psychiatry, 2019, 06-01, Volume: 176, Issue:6 Topics: beta-Cyclodextrins; Brain; Depression, Postpartum; Drug Combinations; Drug Development; Drug Discovery; Female; Humans; Mental Disorders; Molecular Targeted Therapy; National Institute of Mental Health (U.S.); Neurobiology; Neurosteroids; Pregnanolone; Psychiatry; Psychotropic Drugs; Translational Research, Biomedical; United States	2019
Brexanolone, a neurosteroid antidepressant, vindicates the GABAergic deficit hypothesis of depression and may foster resilience. F1000Research, 2019, Volume: 8 Topics: Antidepressive Agents; beta-Cyclodextrins; Depression; Depression, Postpartum; Drug Combinations; Female; GABA Modulators; Humans; Neurosteroids; Pregnanolone; Receptors, GABA-A	2019
Brexanolone for postpartum depression: A meta-analysis of randomized controlled studies. Psychiatry research, 2019, Volume: 279 Topics: Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Pregnanolone; Randomized Controlled Trials as Topic; Treatment Outcome	2019
Allopregnanolone as a mediator of affective switching in reproductive mood disorders. Psychopharmacology, 2014, Volume: 231, Issue:17 Topics: Adult; Affect; Depression, Postpartum; Female; Humans; Mood Disorders; Neurotransmitter Agents; Pregnancy; Pregnanolone; Premenstrual Syndrome	2014
The role of reproductive hormones in postpartum depression. CNS spectrums, 2015, Volume: 20, Issue:1 Topics: Animals; Depression, Postpartum; Estrogens; Female; Humans; Pregnancy; Pregnanolone; Progesterone	2015

Trials

4 trial(s) available for pregnanolone and Depression, Postpartum

Article	Year
Using Matching-Adjusted Indirect Comparisons and Network Meta-analyses to Compare Efficacy of Brexanolone Injection with Selective Serotonin Reuptake Inhibitors for Treating Postpartum Depression. CNS drugs, 2019, Volume: 33, Issue:10 Topics: Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Double-Blind Method; Drug Combinations; Female; Humans; Male; Meta-Analysis as Topic; Network Meta-Analysis; Pregnanolone; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Serotonin	2019
Open-label, proof-of-concept study of brexanolone in the treatment of severe postpartum depression. Human psychopharmacology, 2017, Volume: 32, Issue:2 Topics: Adult; beta-Cyclodextrins; Depression, Postpartum; Double-Blind Method; Drug Combinations; Female; Humans; Infusions, Intravenous; Pregnanolone; Proof of Concept Study; Treatment Outcome	2017
Brexanolone (SAGE-547 injection) in post-partum depression: a randomised controlled trial. Lancet (London, England), 2017, 07-29, Volume: 390, Issue:10093 Topics: Adult; Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Double-Blind Method; Drug Combinations; Female; Humans; Infusions, Intravenous; Pregnanolone; Psychiatric Status Rating Scales; Treatment Outcome; Young Adult	2017
Brexanolone injection in post-partum depression: two multicentre, double-blind, randomised, placebo-controlled, phase 3 trials. Lancet (London, England), 2018, 09-22, Volume: 392, Issue:10152 Topics: Adult; beta-Cyclodextrins; Depression, Postpartum; Double-Blind Method; Drug Combinations; Female; GABA Agonists; Humans; Injections, Intravenous; Pregnancy; Pregnancy Trimester, Third; Pregnanolone; Psychiatric Status Rating Scales; Receptors, GABA; Severity of Illness Index; Treatment Outcome; Young Adult	2018

Other Studies

43 other study(ies) available for pregnanolone and Depression, Postpartum

Article	Year
Allopregnanolone and depression and anxiety symptoms across the peripartum: an exploratory study. Archives of women's mental health, 2022, Volume: 25, Issue:2 Topics: Anxiety; Depression; Depression, Postpartum; Female; Humans; Peripartum Period; Pregnancy; Pregnanolone; Psychiatric Status Rating Scales	2022
Mechanisms Underlying Recovery From Postpartum Depression Following Brexanolone Therapy. Biological psychiatry, 2022, 02-01, Volume: 91, Issue:3 Topics: beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Pregnanolone	2022
Effects of fast-acting antidepressant drugs on a postpartum depression mice model. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 154 Topics: Anhedonia; Animals; Antidepressive Agents; Depression, Postpartum; Disease Models, Animal; Female; Humans; Ketamine; Maternal Deprivation; Mice; Pregnanolone	2022
Implementation of a Hospital-based Brexanolone Program. Journal of psychiatric practice, 2022, 09-01, Volume: 28, Issue:5 Topics: beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Hospitals; Humans; Pregnancy; Pregnanolone	2022
Neuroactive steroids - new possibilities in the treatment of postpartum depression. Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti, 2022,Fall, Volume: 71, Issue:4 Topics: Depression, Postpartum; Female; Humans; Neurosteroids; Pregnancy; Pregnanolone; Receptors, GABA; Sertraline	2022
Paeoniflorin exhibits antidepressant activity in rats with postpartum depression via the TSPO and BDNF‑mTOR pathways. Acta neurobiologiae experimentalis, 2022, Volume: 82, Issue:3 Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Carrier Proteins; Corticosterone; Depression; Depression, Postpartum; Disease Models, Animal; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Fluoxetine; Glucosides; Hippocampus; Humans; Monoterpenes; Pregnancy; Pregnanolone; Progesterone; Rats; Receptors, GABA-A; Stress, Psychological; Sucrose; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha	2022
Implementation of a Hospital-based Brexanolone Program: Erratum. Journal of psychiatric practice, 2023, 01-01, Volume: 29, Issue:1 Topics: Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Female; Humans; Pregnanolone	2023
Divergent Transcriptomic Effects of Allopregnanolone in Postpartum Depression. Genes, 2023, 06-08, Volume: 14, Issue:6 Topics: Antidepressive Agents; Depression, Postpartum; Dimethyl Sulfoxide; Female; Humans; Pregnanolone; Transcriptome	2023
Brexanolone Is the First Drug Specifically for Postpartum Depression. Nursing for women's health, 2019, Volume: 23, Issue:5 Topics: Administration, Intravenous; Adult; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Mothers; Postpartum Period; Pregnanolone; Selective Serotonin Reuptake Inhibitors	2019
Brexanolone for the treatment of patients with postpartum depression. Drugs of today (Barcelona, Spain : 1998), 2019, Volume: 55, Issue:9 Topics: beta-Cyclodextrins; Depression, Postpartum; Drug Approval; Drug Combinations; Female; Humans; Pregnanolone; United States; United States Food and Drug Administration	2019
US Food and Drug Administration approval of esketamine and brexanolone. The lancet. Psychiatry, 2019, Volume: 6, Issue:12 Topics: Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Depressive Disorder, Treatment-Resistant; Drug Combinations; Female; Humans; Ketamine; Pregnanolone; United States; United States Food and Drug Administration	2019
Brexanolone For Postpartum Depression: A Novel Approach and a Call for Comprehensive Postpartum Care. Clinical therapeutics, 2020, Volume: 42, Issue:1 Topics: Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Neurosteroids; Postpartum Period; Pregnancy; Pregnanolone	2020
Cost-Effectiveness of Brexanolone Versus Selective Serotonin Reuptake Inhibitors for the Treatment of Postpartum Depression in the United States. Journal of managed care & specialty pharmacy, 2020, Volume: 26, Issue:5 Topics: Adolescent; Adult; beta-Cyclodextrins; Cost-Benefit Analysis; Depression, Postpartum; Drug Combinations; Female; Humans; Pregnancy; Pregnanolone; Prenatal Care; Psychometrics; Quality-Adjusted Life Years; Selective Serotonin Reuptake Inhibitors; United States; Young Adult	2020
Brexanolone Therapy for Postpartum Depression. JPMA. The Journal of the Pakistan Medical Association, 2020, Volume: 70, Issue:3 Topics: beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; GABA Modulators; Humans; Pregnanolone	2020
Treating postpartum depression with brexanolone. Nursing, 2020, Volume: 50, Issue:5 Topics: Adult; beta-Cyclodextrins; Depression, Postpartum; Drug Approval; Drug Combinations; Female; Humans; Patient Education as Topic; Pregnanolone; Risk Assessment; United States; United States Food and Drug Administration	2020
Anxiolytic and Anti-depressive Like Effects of Translocator Protein (18 kDa) Ligand YL-IPA08 in a Rat Model of Postpartum Depression. Neurochemical research, 2020, Volume: 45, Issue:8 Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Carrier Proteins; Depression, Postpartum; Female; Gene Expression; Hippocampus; Imidazoles; Ligands; Open Field Test; Prefrontal Cortex; Pregnanolone; Progesterone; Pyridines; Rats, Sprague-Dawley; Receptors, GABA-A	2020
Associations between commonly used patient-reported outcome tools in postpartum depression clinical practice and the Hamilton Rating Scale for Depression. Archives of women's mental health, 2020, Volume: 23, Issue:5 Topics: Adult; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Mass Screening; Patient Health Questionnaire; Patient Reported Outcome Measures; Pregnanolone; Psychiatric Status Rating Scales; Sensitivity and Specificity; Severity of Illness Index; Surveys and Questionnaires	2020
Longitudinal proneuroactive and neuroactive steroid profiles in medication-free women with, without and at-risk for perinatal depression: A liquid chromatography-tandem mass spectrometry analysis. Psychoneuroendocrinology, 2020, Volume: 121 Topics: 20-alpha-Dihydroprogesterone; Adult; Anxiety; Chromatography, Liquid; Depression; Depression, Postpartum; Depressive Disorder; Desoxycorticosterone; Female; Humans; Longitudinal Studies; Neurosteroids; Parturition; Pregnancy; Pregnanolone; Pregnenolone; Prenatal Care; Progesterone; Prospective Studies; Risk Factors; Tandem Mass Spectrometry	2020
Maternal and Newborn Safety During the Administration of Brexanolone: AWHONN Practice Brief Number 10. Journal of obstetric, gynecologic, and neonatal nursing : JOGNN, 2020, Volume: 49, Issue:6 Topics: Administration, Intravenous; Adult; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Guidelines as Topic; Humans; Infant, Newborn; Maternal-Child Health Services; Patient Safety; Pregnanolone	2020
Maternal and Newborn Safety During the Administration of Brexanolone: AWHONN Practice Brief Number 10. Nursing for women's health, 2020, Volume: 24, Issue:6 Topics: Antidepressive Agents; beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Health Personnel; Humans; Infant, Newborn; Infusions, Intravenous; Length of Stay; Mothers; Patient Safety; Pregnanolone; Severity of Illness Index; Workforce	2020
Evaluating brexanolone for the treatment of postpartum depression. Expert opinion on pharmacotherapy, 2021, Volume: 22, Issue:8 Topics: beta-Cyclodextrins; Child; Depression, Postpartum; Drug Combinations; Female; Humans; Pregnancy; Pregnanolone	2021
Prenatal Exposure to Bisphenols and Phthalates and Postpartum Depression: The Role of Neurosteroid Hormone Disruption. The Journal of clinical endocrinology and metabolism, 2021, 06-16, Volume: 106, Issue:7 Topics: Adult; Benzhydryl Compounds; Depression, Postpartum; Endocrine Disruptors; Female; Humans; Maternal Exposure; Neurosteroids; Phenols; Phthalic Acids; Postpartum Period; Pregnancy; Pregnancy Trimesters; Pregnanolone; Pregnenolone; Progesterone; Prospective Studies; Psychiatric Status Rating Scales	2021
Using Brexanolone for Postpartum Depression Must Account for Lactation. Maternal and child health journal, 2021, Volume: 25, Issue:7 Topics: beta-Cyclodextrins; Breast Feeding; Depression, Postpartum; Drug Combinations; Female; Humans; Lactation; Milk, Human; Postpartum Period; Pregnanolone	2021
Allopregnanolone levels and depressive symptoms during pregnancy in relation to single nucleotide polymorphisms in the allopregnanolone synthesis pathway. Hormones and behavior, 2017, Volume: 94 Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adult; Depression; Depression, Postpartum; Female; Genetic Association Studies; Humans; Hydroxysteroid Dehydrogenases; Membrane Proteins; Metabolic Networks and Pathways; Oxidoreductases; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications; Pregnanolone; Psychiatric Status Rating Scales	2017
Neuroactive Steroids. 2. 3α-Hydroxy-3β-methyl-21-(4-cyano-1H-pyrazol-1'-yl)-19-nor-5β-pregnan-20-one (SAGE-217): A Clinical Next Generation Neuroactive Steroid Positive Allosteric Modulator of the (γ-Aminobutyric Acid) Journal of medicinal chemistry, 2017, 09-28, Volume: 60, Issue:18 Topics: Allosteric Regulation; Animals; Depression, Postpartum; Depressive Disorder, Major; Female; GABA-A Receptor Agonists; Mice; Pregnanolone; Pyrazoles; Rats; Receptors, GABA-A	2017
Resting-state functional connectivity, cortical GABA, and neuroactive steroids in peripartum and peripartum depressed women: a functional magnetic resonance imaging and spectroscopy study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2019, Volume: 44, Issue:3 Topics: Adult; Cerebral Cortex; Connectome; Creatine; Depression, Postpartum; Female; gamma-Aminobutyric Acid; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Neurosteroids; Pregnanolone; Proton Magnetic Resonance Spectroscopy; Young Adult	2019
GABA Cell, 2019, 01-10, Volume: 176, Issue:1-2 Topics: Adult; beta-Cyclodextrins; Depression, Postpartum; Depressive Disorder, Major; Drug Combinations; Female; Humans; Mood Disorders; Neurotransmitter Agents; Postpartum Period; Pregnancy; Pregnanolone; Prevalence; Receptors, GABA-A	2019
Brexanolone: First Global Approval. Drugs, 2019, Volume: 79, Issue:7 Topics: Administration, Intravenous; Adolescent; Adult; Allosteric Regulation; beta-Cyclodextrins; Depression, Postpartum; Drug Approval; Drug Combinations; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pregnanolone; Receptors, Steroid; Treatment Outcome; United States; United States Food and Drug Administration	2019
Brexanolone (Zulresso) for postpartum depression. The Medical letter on drugs and therapeutics, 2019, May-06, Volume: 61, Issue:1571 Topics: beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Pregnancy; Pregnanolone; Receptors, GABA-A	2019
Seeing the whole picture of postpartum depression. The lancet. Psychiatry, 2019, Volume: 6, Issue:7 Topics: beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; Humans; Pregnanolone	2019
The First Food and Drug Administration-Indicated Drug for Postpartum Depression-Brexanolone. JAMA psychiatry, 2019, 10-01, Volume: 76, Issue:10 Topics: beta-Cyclodextrins; Depression, Postpartum; Double-Blind Method; Drug Combinations; Female; Humans; Pregnanolone; United States; United States Food and Drug Administration	2019
Brexanolone injection for post-partum depression treatment. Lancet (London, England), 2019, 08-03, Volume: 394, Issue:10196 Topics: beta-Cyclodextrins; Depression, Postpartum; Double-Blind Method; Drug Combinations; Female; Humans; Pregnanolone	2019
Brexanolone injection for post-partum depression treatment - Authors' reply. Lancet (London, England), 2019, 08-03, Volume: 394, Issue:10196 Topics: beta-Cyclodextrins; Depression, Postpartum; Double-Blind Method; Drug Combinations; Female; Humans; Pregnanolone	2019
Brexanolone injection for post-partum depression treatment. Lancet (London, England), 2019, 08-03, Volume: 394, Issue:10196 Topics: beta-Cyclodextrins; Depression, Postpartum; Double-Blind Method; Drug Combinations; Female; Humans; Pregnanolone	2019
Brexanolone and postpartum depression: what does it have to do with GABA? Archives of women's mental health, 2019, Volume: 22, Issue:6 Topics: beta-Cyclodextrins; Depression, Postpartum; Drug Combinations; Female; GABA Modulators; gamma-Aminobutyric Acid; Humans; Pregnanolone	2019
GABAergic neuroactive steroids and resting-state functional connectivity in postpartum depression: a preliminary study. Journal of psychiatric research, 2013, Volume: 47, Issue:6 Topics: Adult; Amygdala; Depression, Postpartum; Female; Gyrus Cinguli; Hippocampus; Humans; Magnetic Resonance Imaging; Nerve Net; Pilot Projects; Postpartum Period; Prefrontal Cortex; Pregnancy; Pregnanolone; Pregnenolone	2013
Low serum allopregnanolone is associated with symptoms of depression in late pregnancy. Neuropsychobiology, 2014, Volume: 69, Issue:3 Topics: Adult; Anxiety; Depression; Depression, Postpartum; Female; Humans; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Third; Pregnanolone; Self Report; Young Adult	2014
Replication of Epigenetic Postpartum Depression Biomarkers and Variation with Hormone Levels. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016, Volume: 41, Issue:6 Topics: Adult; Depression, Postpartum; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Estradiol; Female; Genetic Markers; Humans; Nerve Tissue Proteins; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Pregnancy; Pregnanolone; Progesterone	2016
Oxytocin receptor DNA methylation in postpartum depression. Psychoneuroendocrinology, 2016, Volume: 69 Topics: Adult; Anxiety; Anxiety Disorders; CpG Islands; Depression, Postpartum; DNA Methylation; Epigenesis, Genetic; Estradiol; Female; Humans; Pregnanolone; Progesterone; Prospective Studies; Receptors, Oxytocin	2016
Peripartum neuroactive steroid and γ-aminobutyric acid profiles in women at-risk for postpartum depression. Psychoneuroendocrinology, 2016, Volume: 70 Topics: 20-alpha-Dihydroprogesterone; Adult; Case-Control Studies; Depression, Postpartum; Desoxycorticosterone; Female; gamma-Aminobutyric Acid; Humans; Longitudinal Studies; Peripartum Period; Pregnancy; Pregnanolone; Progesterone; Receptors, GABA-A; Risk Factors; Steroids	2016
Lower allopregnanolone during pregnancy predicts postpartum depression: An exploratory study. Psychoneuroendocrinology, 2017, Volume: 79 Topics: Adolescent; Adult; Depression, Postpartum; Female; Humans; Middle Aged; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, Third; Pregnanolone; Progesterone; Young Adult	2017
3alpha-reduced neuroactive steroids and their precursors during pregnancy and the postpartum period. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2005, Volume: 21, Issue:5 Topics: 5-alpha-Dihydroprogesterone; Adult; Delivery, Obstetric; Depression, Postpartum; Female; Gas Chromatography-Mass Spectrometry; Gestational Age; Humans; Labor Onset; Parity; Postpartum Period; Pregnancy; Pregnanolone; Pregnenolone; Progesterone	2005
Serum allopregnanolone in women with postpartum "blues". Obstetrics and gynecology, 2001, Volume: 97, Issue:1 Topics: Adult; Biomarkers; Depression, Postpartum; Female; Humans; Pregnanolone; Progesterone; Prospective Studies	2001