Page last updated: 2024-08-23

pregnanolone and Demyelinating Diseases

pregnanolone has been researched along with Demyelinating Diseases in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Crombie, GK; Hirst, JJ; Hodgson, DM; Palliser, HK; Shaw, JC; Walker, DW1
Benyounes, J; Bihel, F; Collongues, N; De Seze, J; Hallé, F; Klein, C; Leva, G; Mensah-Nyagan, AG; Patte-Mensah, C1
Kalakh, S; Mouihate, A2
Ahmad, I; Bi, X; Chaitkin, E; Erickson, RP; Hicks, C; Howison, CM; Lope-Piedrafita, S; Trouard, TP; Weberg, L; Yao, Y; Yu, C1
Baumann, N; Eychenne, B; Lachapelle, F; Le Goascogne, C; Robel, P; Tonon, MC1

Other Studies

6 other study(ies) available for pregnanolone and Demyelinating Diseases

ArticleYear
Neurosteroid-based intervention using Ganaxolone and Emapunil for improving stress-induced myelination deficits and neurobehavioural disorders.
    Psychoneuroendocrinology, 2021, Volume: 133

    Topics: Animals; Demyelinating Diseases; Female; Guinea Pigs; Male; Mental Disorders; Nervous System Diseases; Neuropsychological Tests; Neurosteroids; Pregnancy; Pregnanolone; Prenatal Exposure Delayed Effects; Purines; Stress, Psychological

2021
The translocator protein ligand XBD173 improves clinical symptoms and neuropathological markers in the SJL/J mouse model of multiple sclerosis.
    Biochimica et biophysica acta. Molecular basis of disease, 2017, Volume: 1863, Issue:12

    Topics: Animals; Biomarkers; Brain; Cytokines; Demyelinating Diseases; Encephalomyelitis, Autoimmune, Experimental; Female; Ligands; Mice; Mice, Inbred Strains; Multiple Sclerosis, Relapsing-Remitting; Myelin Basic Protein; Neurotransmitter Agents; Pregnanolone; Purines; Receptors, GABA; RNA, Messenger; Spinal Cord

2017
Enhanced remyelination during late pregnancy: involvement of the GABAergic system.
    Scientific reports, 2019, 05-22, Volume: 9, Issue:1

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Animals; Bicuculline; Corpus Callosum; Demyelinating Diseases; Disease Models, Animal; Female; Finasteride; GABA Antagonists; Lysophosphatidylcholines; Male; Microglia; Multiple Sclerosis; Myelin Proteins; Myelin Sheath; Nerve Tissue Proteins; Oligodendrocyte Precursor Cells; Oligodendroglia; Pregnancy; Pregnancy Complications; Pregnanolone; Puerperal Disorders; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Remyelination

2019
Ganaxolone enhances microglial clearance activity and promotes remyelination in focal demyelination in the corpus callosum of ovariectomized rats.
    CNS neuroscience & therapeutics, 2020, Volume: 26, Issue:2

    Topics: Animals; Corpus Callosum; Demyelinating Diseases; Female; Lysophosphatidylcholines; Microglia; Myelin Proteins; Ovariectomy; Pregnanolone; Rats; Rats, Sprague-Dawley; Remyelination

2020
Allopregnanolone treatment, both as a single injection or repetitively, delays demyelination and enhances survival of Niemann-Pick C mice.
    Journal of neuroscience research, 2005, Dec-15, Volume: 82, Issue:6

    Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Age Factors; Anesthetics; Animals; Anisotropy; Antigens, Differentiation; Body Weight; Brain; Cell Count; Cell Survival; Demyelinating Diseases; Disease Models, Animal; Drug Administration Schedule; Glial Fibrillary Acidic Protein; Immunohistochemistry; Magnetic Resonance Imaging; Membrane Transport Proteins; Mice; Mice, Inbred BALB C; Mice, Knockout; Motor Activity; Niemann-Pick Diseases; Pregnanolone; Time Factors

2005
Neurosteroid progesterone is up-regulated in the brain of jimpy and shiverer mice.
    Glia, 2000, Jan-01, Volume: 29, Issue:1

    Topics: 5-alpha-Dihydroprogesterone; Adrenal Cortex; Animals; Brain; Brain Chemistry; Corticosterone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Demyelinating Diseases; Diazepam Binding Inhibitor; Immunohistochemistry; Leydig Cells; Male; Mice; Mice, Inbred Strains; Mice, Jimpy; Mice, Neurologic Mutants; Neuropeptides; Organ Specificity; Peptide Fragments; Pregnanediones; Pregnanolone; Pregnenolone; Progesterone; Radioimmunoassay; Receptors, Cytoplasmic and Nuclear; Up-Regulation

2000