Page last updated: 2024-08-23

pregnanolone and Cognition Disorders

pregnanolone has been researched along with Cognition Disorders in 7 studies

Research

Studies (7)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (28.57)	18.2507
2000's	2 (28.57)	29.6817
2010's	3 (42.86)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Esmaeili-Mahani, S; Esmaeilpour, K; Nezhadi, A; Shabani, M; Sheibani, V	1
Bradford, DW; Buchanan, RW; Dunn, L; Hamer, RM; Keefe, RS; Kilts, JD; Leimone, LA; Lieberman, JA; Marx, CE; Morrow, AL; Naylor, JC; Payne, VM; Porcu, P; Savitz, AJ; Shampine, LJ; Strauss, JL	1
Frye, CA; Paris, JJ	1
Bubenikova-Valesova, V; Chodounska, H; Holubova, K; Rambousek, L; Stuchlik, A; Svoboda, J; Vales, K; Vyklicky, L	1
Aszalós, Z	1
Cheney, DL; Costa, E; Guidotti, A; Romeo, E; Zivkovic, I	1
Akhondzadeh, S; Stone, TW	1

Reviews

1 review(s) available for pregnanolone and Cognition Disorders

Article	Year
[Neurological and psychiatric aspects of some endocrine diseases. The role of neurosteroids and neuroactive steroids]. Orvosi hetilap, 2007, Oct-14, Volume: 148, Issue:41 Topics: Addison Disease; Adrenal Cortex Hormones; Androgens; Anxiety; Cognition Disorders; Cushing Syndrome; Depression; Endocrine System Diseases; Estrogens; Fear; Fetal Organ Maturity; Gonadal Steroid Hormones; Humans; Memory Disorders; Mental Disorders; Mood Disorders; Muscle Weakness; Nervous System Diseases; Pain; Pregnanolone; Progesterone	2007

Article

Year

[Neurological and psychiatric aspects of some endocrine diseases. The role of neurosteroids and neuroactive steroids].

Orvosi hetilap, 2007, Oct-14, Volume: 148, Issue:41

Topics: Addison Disease; Adrenal Cortex Hormones; Androgens; Anxiety; Cognition Disorders; Cushing Syndrome; Depression; Endocrine System Diseases; Estrogens; Fear; Fetal Organ Maturity; Gonadal Steroid Hormones; Humans; Memory Disorders; Mental Disorders; Mood Disorders; Muscle Weakness; Nervous System Diseases; Pain; Pregnanolone; Progesterone

2007

Trials

1 trial(s) available for pregnanolone and Cognition Disorders

Article	Year
Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:8 Topics: Adult; Aged; Brain; Brain Chemistry; Cognition Disorders; Double-Blind Method; Female; Humans; Male; Memory Disorders; Middle Aged; Neuropsychological Tests; Nootropic Agents; Pilot Projects; Placebos; Pregnanolone; Pregnenolone; Schizophrenia; Treatment Outcome; Up-Regulation	2009

Article

Year

Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophrenia.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:8

Topics: Adult; Aged; Brain; Brain Chemistry; Cognition Disorders; Double-Blind Method; Female; Humans; Male; Memory Disorders; Middle Aged; Neuropsychological Tests; Nootropic Agents; Pilot Projects; Placebos; Pregnanolone; Pregnenolone; Schizophrenia; Treatment Outcome; Up-Regulation

2009

Other Studies

5 other study(ies) available for pregnanolone and Cognition Disorders

Article	Year
Neurosteroid allopregnanolone attenuates cognitive dysfunctions in 6-OHDA-induced rat model of Parkinson's disease. Behavioural brain research, 2016, May-15, Volume: 305 Topics: Adrenergic Agents; Analysis of Variance; Animals; Cognition Disorders; Disease Models, Animal; Escape Reaction; Exploratory Behavior; Male; Maze Learning; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Pregnanolone; Rats; Rats, Wistar; Reaction Time; Recognition, Psychology; Substantia Nigra	2016
Juvenile offspring of rats exposed to restraint stress in late gestation have impaired cognitive performance and dysregulated progestogen formation. Stress (Amsterdam, Netherlands), 2011, Volume: 14, Issue:1 Topics: Animals; Cognition Disorders; Corticosterone; Exploratory Behavior; Female; Male; Maternal Exposure; Prefrontal Cortex; Pregnancy; Pregnanolone; Progesterone; Progestins; Rats; Rats, Long-Evans; Restraint, Physical; Stress, Physiological	2011
3α5β-Pregnanolone glutamate, a use-dependent NMDA antagonist, reversed spatial learning deficit in an animal model of schizophrenia. Behavioural brain research, 2012, Nov-01, Volume: 235, Issue:1 Topics: Animals; Anxiety; Avoidance Learning; Cognition Disorders; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Male; Motor Activity; Pregnanolone; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Vocalization, Animal	2012
Mitochondrial diazepam-binding inhibitor receptor complex agonists antagonize dizocilpine amnesia: putative role for allopregnanolone. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:1 Topics: Amnesia; Animals; Avoidance Learning; Cognition; Cognition Disorders; Dizocilpine Maleate; Indoleacetic Acids; Male; Mitochondria; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Scopolamine; Steroids; Tritium	1994
Potentiation of muscimol-induced long-term depression by benzodiazepines and prevention or reversal by pregnenolone sulfate. Pharmacological research, 1998, Volume: 38, Issue:6 Topics: Amnesia; Animals; Barbiturates; Benzodiazepines; Cognition Disorders; Depression; Diazepam; Drug Synergism; Hippocampus; In Vitro Techniques; Male; Muscimol; Pentobarbital; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Time Factors	1998