Page last updated: 2024-08-23

pregnanolone and Cerebral Ischemia

pregnanolone has been researched along with Cerebral Ischemia in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's6 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kleteckova, L; Kubova, H; Stuchlik, A; Tsenov, G; Vales, K1
De Nicola, AF; Gonzalez Deniselle, MC; Guennoun, R; Labombarda, F; Liere, P; Schumacher, M1
Ardeshiri, A; Herson, PS; Hurn, PD; Kelley, MH; Kuroiwa, M; Taguchi, N; Traystman, RJ1
Bai, Y; Cai, W; Chen, L; Sokabe, M; Yang, R; Zhang, Z1
Atif, F; Hua, F; Ishrat, T; Sayeed, I; Stein, DG1
Cervantes, M; Espinosa-García, C; Hernández-Morales, L; Monfil, T; Montes, P; Moralí, G1
Davidson, C; Gibson, CL; Knight, SR; Young, AM1
Lapchak, PA1

Reviews

1 review(s) available for pregnanolone and Cerebral Ischemia

ArticleYear
Progesterone and allopregnanolone in the central nervous system: response to injury and implication for neuroprotection.
    The Journal of steroid biochemistry and molecular biology, 2015, Volume: 146

    Topics: Animals; Brain; Brain Injuries; Brain Ischemia; Central Nervous System; Female; Humans; Male; Membrane Proteins; Neurodegenerative Diseases; Neuroprotective Agents; Pregnanolone; Progesterone; Receptors, GABA-A; Receptors, Progesterone; Spinal Cord; Spinal Cord Injuries

2015

Other Studies

7 other study(ies) available for pregnanolone and Cerebral Ischemia

ArticleYear
Neuroprotective effect of the 3α5β-pregnanolone glutamate treatment in the model of focal cerebral ischemia in immature rats.
    Neuroscience letters, 2014, Apr-03, Volume: 564

    Topics: Animals; Brain Ischemia; Disease Models, Animal; Glutamates; Hippocampus; Male; Neuroprotective Agents; Pregnanolone; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

2014
Ischemic insult to cerebellar Purkinje cells causes diminished GABAA receptor function and allopregnanolone neuroprotection is associated with GABAA receptor stabilization.
    Journal of neurochemistry, 2008, Volume: 107, Issue:3

    Topics: Animals; Blotting, Western; Brain Ischemia; Immunohistochemistry; Inhibitory Postsynaptic Potentials; Mice; Neuroprotective Agents; Patch-Clamp Techniques; Pregnanolone; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction

2008
Treatment with progesterone after focal cerebral ischemia suppresses proliferation of progenitor cells but enhances survival of newborn neurons in adult male mice.
    Neuropharmacology, 2010, Volume: 58, Issue:6

    Topics: Adult Stem Cells; Animals; Brain; Brain Ischemia; Cell Movement; Cell Proliferation; Cell Survival; Corpus Striatum; Dentate Gyrus; Extracellular Signal-Regulated MAP Kinases; Infarction, Middle Cerebral Artery; Male; MAP Kinase Signaling System; Mice; Neurogenesis; Neurons; Neuroprotective Agents; Pregnanolone; Progesterone; Stem Cell Niche; Time Factors

2010
Progesterone and allopregnanolone attenuate blood-brain barrier dysfunction following permanent focal ischemia by regulating the expression of matrix metalloproteinases.
    Experimental neurology, 2010, Volume: 226, Issue:1

    Topics: Animals; Blood-Brain Barrier; Blotting, Western; Brain Edema; Brain Ischemia; Claudin-5; Immunohistochemistry; Infarction, Middle Cerebral Artery; Interleukin-6; Ligation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Membrane Proteins; Middle Cerebral Artery; Occludin; Permeability; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Stroke; Tumor Necrosis Factor-alpha

2010
Neuroprotective effects of progesterone and allopregnanolone on long-term cognitive outcome after global cerebral ischemia.
    Restorative neurology and neuroscience, 2011, Volume: 29, Issue:1

    Topics: Animals; Brain Ischemia; Cognition; Disease Models, Animal; Male; Maze Learning; Memory Disorders; Neuroprotective Agents; Pregnanolone; Progesterone; Random Allocation; Rats; Rats, Sprague-Dawley; Swimming; Time Factors; Treatment Outcome

2011
Allopregnanolone protects against dopamine-induced striatal damage after in vitro ischaemia via interaction at GABA A receptors.
    Journal of neuroendocrinology, 2012, Volume: 24, Issue:8

    Topics: Animals; Brain Ischemia; Corpus Striatum; Dopamine; GABA Agonists; In Vitro Techniques; Male; Mice; Pregnanolone; Receptors, GABA-A

2012
3alpha-OL-5-beta-pregnan-20-one hemisuccinate, a steroidal low-affinity NMDA receptor antagonist improves clinical rating scores in a rabbit multiple infarct ischemia model: synergism with tissue plasminogen activator.
    Experimental neurology, 2006, Volume: 197, Issue:2

    Topics: Animals; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Fibrinolytic Agents; Male; Pregnanolone; Rabbits; Receptors, N-Methyl-D-Aspartate; Time Factors; Tissue Plasminogen Activator; Treatment Outcome

2006