Page last updated: 2024-08-23

pregnanolone and Cerebral Infarction, Middle Cerebral Artery

pregnanolone has been researched along with Cerebral Infarction, Middle Cerebral Artery in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Calford, MB; McLeod, DD; Pepperall, D; Spratt, NJ; Tomkins, AJ1
Chao, D; Kim, JK; Kuo, L; Lee, RJ; Mally, A; McClean, ME; Murphy, SP; Pemberton, HE; Wilmington, AR; Wong, J1
Parvez, S; Sayeed, I; Siemen, D; Stein, DG; Wali, B1
Bai, Y; Cai, W; Chen, L; Sokabe, M; Yang, R; Zhang, Z1
Atif, F; Hua, F; Ishrat, T; Sayeed, I; Stein, DG1
Guo, Q; Hoffman, SW; Sayeed, I; Stein, DG1

Other Studies

6 other study(ies) available for pregnanolone and Cerebral Infarction, Middle Cerebral Artery

ArticleYear
Allopregnanolone and its precursor progesterone do not reduce injury after experimental stroke in hypertensive rats - role of postoperative temperature regulation?
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Animals; Body Temperature Regulation; Disease Models, Animal; Infarction, Middle Cerebral Artery; Male; Motor Activity; Neuroprotective Agents; Postoperative Period; Pregnanolone; Progesterone; Rats; Rats, Inbred SHR; Temperature

2014
Progesterone and allopregnanolone improves stroke outcome in male mice via distinct mechanisms but neither promotes neurogenesis.
    Journal of neurochemistry, 2015, Volume: 132, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Pregnanolone; Progesterone; Receptors, Progesterone; Stroke; Treatment Outcome

2015
Direct inhibition of the mitochondrial permeability transition pore: a possible mechanism for better neuroprotective effects of allopregnanolone over progesterone.
    Brain research, 2009, Mar-31, Volume: 1263

    Topics: Animals; Brain; Brain Injuries; Calcium; Cell Membrane Permeability; Cytochromes c; Infarction, Middle Cerebral Artery; Liver; Male; Membrane Potential, Mitochondrial; Mitochondria; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Membranes; Mitochondrial Permeability Transition Pore; Neuroprotective Agents; Patch-Clamp Techniques; Pregnanolone; Progesterone; Rats; Rats, Wistar

2009
Treatment with progesterone after focal cerebral ischemia suppresses proliferation of progenitor cells but enhances survival of newborn neurons in adult male mice.
    Neuropharmacology, 2010, Volume: 58, Issue:6

    Topics: Adult Stem Cells; Animals; Brain; Brain Ischemia; Cell Movement; Cell Proliferation; Cell Survival; Corpus Striatum; Dentate Gyrus; Extracellular Signal-Regulated MAP Kinases; Infarction, Middle Cerebral Artery; Male; MAP Kinase Signaling System; Mice; Neurogenesis; Neurons; Neuroprotective Agents; Pregnanolone; Progesterone; Stem Cell Niche; Time Factors

2010
Progesterone and allopregnanolone attenuate blood-brain barrier dysfunction following permanent focal ischemia by regulating the expression of matrix metalloproteinases.
    Experimental neurology, 2010, Volume: 226, Issue:1

    Topics: Animals; Blood-Brain Barrier; Blotting, Western; Brain Edema; Brain Ischemia; Claudin-5; Immunohistochemistry; Infarction, Middle Cerebral Artery; Interleukin-6; Ligation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Membrane Proteins; Middle Cerebral Artery; Occludin; Permeability; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Stroke; Tumor Necrosis Factor-alpha

2010
Allopregnanolone, a progesterone metabolite, is more effective than progesterone in reducing cortical infarct volume after transient middle cerebral artery occlusion.
    Annals of emergency medicine, 2006, Volume: 47, Issue:4

    Topics: Analysis of Variance; Animals; Autopsy; Brain; Cerebrovascular Circulation; Data Interpretation, Statistical; Disease Models, Animal; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Injections, Subcutaneous; Laser-Doppler Flowmetry; Male; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors

2006