pregnanolone has been researched along with Brain Injuries in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (66.67) | 29.6817 |
| 2010's | 5 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Casarosa, E; Genazzani, AD; Genazzani, AR; Petignat, P; Pluchino, N; Santoro, A; Wenger, JM | 1 |
| De Nicola, AF; Gonzalez Deniselle, MC; Guennoun, R; Labombarda, F; Liere, P; Schumacher, M | 1 |
| Cekic, M; Cutler, SM; Hoffman, SW; Johnson, SJ; Miller, D; Stein, DG; VanLandingham, JW; Washington, ER | 1 |
| Parvez, S; Sayeed, I; Siemen, D; Stein, DG; Wali, B | 1 |
| Atif, F; Liotta, DC; MacNevin, CJ; Sayeed, I; Stein, DG | 1 |
| Cohen, P | 1 |
| Calnaido, RP; Hamer, RM; Keefe, FJ; Kilts, JD; Marx, CE; Massing, MW; Morey, RA; Naylor, JC; Parke, G; Payne, VM; Shampine, LJ; Strauss, JL; Tupler, LA; Youssef, NA | 1 |
| Ikeda, T; Kasahara, Y; Ohshima, M; Taguchi, A; Tsuji, M | 1 |
| Djebaili, M; Hoffman, SW; Stein, DG | 1 |
| He, J; Hoffman, SW; Stein, DG | 1 |
| Evans, CO; He, J; Hoffman, SW; Oyesiku, NM; Stein, DG | 1 |
| Djebaili, M; Guo, Q; Hoffman, SW; Pettus, EH; Stein, DG | 1 |
| Cutler, SM; Stein, DG; Vanlandingham, JW | 1 |
| Hirst, JJ; Walker, DW; Yan, EB; Yawno, T | 1 |
| Cekic, M; Cutler, S; Hoffman, SW; Stein, DG; VanLandingham, JW | 1 |
2 review(s) available for pregnanolone and Brain Injuries
| Article | Year |
|---|---|
Advances in neurosteroids: role in clinical practice.
Topics: Affect; Aging; Behavior; Brain Injuries; Cognition; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Male; Menopause; Neurotransmitter Agents; Postpartum Period; Pregnancy; Pregnanolone; Premenstrual Syndrome; Progesterone; Reproduction | 2013 |
Progesterone and allopregnanolone in the central nervous system: response to injury and implication for neuroprotection.
Topics: Animals; Brain; Brain Injuries; Brain Ischemia; Central Nervous System; Female; Humans; Male; Membrane Proteins; Neurodegenerative Diseases; Neuroprotective Agents; Pregnanolone; Progesterone; Receptors, GABA-A; Receptors, Progesterone; Spinal Cord; Spinal Cord Injuries | 2015 |
13 other study(ies) available for pregnanolone and Brain Injuries
| Article | Year |
|---|---|
Progesterone and its metabolite allopregnanolone differentially regulate hemostatic proteins after traumatic brain injury.
Topics: Animals; Blood Coagulation; Brain Injuries; Disease Models, Animal; Factor XIII; Fibrinogen; Gene Expression Regulation; Hemostasis; Humans; Male; Neuropeptides; Neuroserpin; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serpins; Thrombin; Tissue Plasminogen Activator | 2008 |
Direct inhibition of the mitochondrial permeability transition pore: a possible mechanism for better neuroprotective effects of allopregnanolone over progesterone.
Topics: Animals; Brain; Brain Injuries; Calcium; Cell Membrane Permeability; Cytochromes c; Infarction, Middle Cerebral Artery; Liver; Male; Membrane Potential, Mitochondrial; Mitochondria; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Membranes; Mitochondrial Permeability Transition Pore; Neuroprotective Agents; Patch-Clamp Techniques; Pregnanolone; Progesterone; Rats; Rats, Wistar | 2009 |
Development and screening of water-soluble analogues of progesterone and allopregnanolone in models of brain injury.
Topics: Animals; Brain Edema; Brain Injuries; Drug Evaluation, Preclinical; Female; Ketones; Male; Models, Animal; Oximes; Pregnanolone; Progesterone; Rats; Solubility; Structure-Activity Relationship | 2009 |
Do 5-alpha reductase inhibitors influence the severity of brain injury in men after a stroke?
Topics: Brain Injuries; Cholestenone 5 alpha-Reductase; Humans; Male; Pregnanolone; Prostatic Hyperplasia; Stroke | 2010 |
Neurosteroids and self-reported pain in veterans who served in the U.S. Military after September 11, 2001.
Topics: Adult; Afghanistan; Brain Injuries; Dehydroepiandrosterone; Female; Gas Chromatography-Mass Spectrometry; Humans; Linear Models; Male; Military Personnel; Neurotransmitter Agents; Pain; Pain Measurement; Pregnanolone; Smoking; United States; Veterans | 2010 |
Progesterone and allopregnanolone exacerbate hypoxic-ischemic brain injury in immature rats.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Bicuculline; Brain; Brain Injuries; Disease Models, Animal; Drug Administration Routes; Functional Laterality; GABA-A Receptor Antagonists; Hypoxia-Ischemia, Brain; Pregnanolone; Progesterone; Rats; Rats, Wistar; Time Factors | 2012 |
Allopregnanolone and progesterone decrease cell death and cognitive deficits after a contusion of the rat pre-frontal cortex.
Topics: Animals; Apoptosis; Brain Injuries; Caspase 3; Caspases; Cell Death; Cognition; Enzyme-Linked Immunosorbent Assay; Male; Neuroprotective Agents; Prefrontal Cortex; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Time Factors | 2004 |
Allopregnanolone, a progesterone metabolite, enhances behavioral recovery and decreases neuronal loss after traumatic brain injury.
Topics: Analysis of Variance; Anesthetics; Animals; Basal Nucleus of Meynert; Behavior, Animal; Brain Injuries; Cell Count; Choline O-Acetyltransferase; Disease Models, Animal; Drug Administration Schedule; Immunohistochemistry; Male; Maze Learning; Mediodorsal Thalamic Nucleus; Motor Activity; Pregnanolone; Rats; Rats, Sprague-Dawley; Reaction Time; Regeneration; Spatial Behavior; Time Factors | 2004 |
Progesterone and allopregnanolone reduce inflammatory cytokines after traumatic brain injury.
Topics: Animals; Brain Edema; Brain Injuries; Cytokines; Disease Models, Animal; Down-Regulation; Drug Administration Schedule; Encephalitis; Gene Expression; Interleukin-1; Male; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Reaction Time; RNA, Messenger; Treatment Outcome; Tumor Necrosis Factor-alpha | 2004 |
The neurosteroids progesterone and allopregnanolone reduce cell death, gliosis, and functional deficits after traumatic brain injury in rats.
Topics: Animals; Apoptosis; Astrocytes; bcl-2-Associated X Protein; Brain Injuries; Caspase 3; Caspases; DNA Fragmentation; Male; Maze Learning; Neurons; Neuroprotective Agents; Pregnanolone; Progesterone; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Time Factors | 2005 |
Tapered progesterone withdrawal promotes long-term recovery following brain trauma.
Topics: Anesthetics; Animals; Behavior, Animal; Blotting, Western; Brain Injuries; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Drug Administration Schedule; Glial Fibrillary Acidic Protein; HSP70 Heat-Shock Proteins; Immunohistochemistry; Male; Motor Activity; Peptides, Cyclic; Perceptual Disorders; Pregnanolone; Random Allocation; Rats; Rats, Sprague-Dawley; Recovery of Function; Substance Withdrawal Syndrome; Time Factors; Tumor Suppressor Protein p53; Upper Extremity | 2006 |
Inhibition of neurosteroid synthesis increases asphyxia-induced brain injury in the late gestation fetal sheep.
Topics: Animals; Apoptosis; Asphyxia; Brain Injuries; Caspase 3; Enzyme Inhibitors; Female; Fetus; Finasteride; Gestational Age; Goats; Heart Rate; Oxygen; Pregnancy; Pregnanolone; Radioimmunoassay; Umbilical Cord | 2007 |
Neurosteroids reduce inflammation after TBI through CD55 induction.
Topics: Animals; Anti-Inflammatory Agents; Brain Injuries; CD55 Antigens; Cell Death; Cerebral Cortex; Complement C3-C5 Convertases; Complement System Proteins; Encephalitis; Gliosis; Male; Neuroglia; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Steroids; Time Factors; Treatment Outcome | 2007 |