Page last updated: 2024-08-23

pregnanolone and Brain Inflammation

pregnanolone has been researched along with Brain Inflammation in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bannister, E1
Fu, Q; Guo, WZ; Jiao, LB; Liu, N; Ma, L; Ma, YQ; Mi, WD; Wang, PQ; Zhang, H1
Cheng, GG; Dong, LQ; Li, YF; Ma, L; Ma, YQ; Xu, BN; Yin, YL; Zhang, H1
Bi, X; Cheung, S; Galeano, J; Ji, AX; Liao, G; Qin, Q1
Baker, GB; Ellestad, KK; Han, MH; Maingat, F; Noorbakhsh, F; Power, C; Steinman, L; Warren, KG1
Evans, CO; He, J; Hoffman, SW; Oyesiku, NM; Stein, DG1
Cekic, M; Cutler, S; Hoffman, SW; Stein, DG; VanLandingham, JW1

Reviews

1 review(s) available for pregnanolone and Brain Inflammation

ArticleYear
There is increasing evidence to suggest that brain inflammation could play a key role in the aetiology of psychiatric illness. Could inflammation be a cause of the premenstrual syndromes PMS and PMDD?
    Post reproductive health, 2019, Volume: 25, Issue:3

    Topics: Encephalitis; Female; Gonadal Steroid Hormones; Humans; Pregnanolone; Premenstrual Dysphoric Disorder; Premenstrual Syndrome; Receptors, GABA-A; Stress, Psychological

2019

Other Studies

6 other study(ies) available for pregnanolone and Brain Inflammation

ArticleYear
TSPO ligand PK11195 alleviates neuroinflammation and beta-amyloid generation induced by systemic LPS administration.
    Brain research bulletin, 2016, Volume: 121

    Topics: Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Anti-Inflammatory Agents; Aspartic Acid Endopeptidases; Brain-Derived Neurotrophic Factor; Cyclooxygenase 2; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalitis; Gene Expression Regulation; Hippocampus; Isoquinolines; Lipopolysaccharides; Male; Maze Learning; Mice; Mice, Inbred C57BL; Pregnanolone; Progesterone; Receptors, GABA

2016
Over-expression of TSPO in the hippocampal CA1 area alleviates cognitive dysfunction caused by lipopolysaccharide in mice.
    Brain research, 2016, 09-01, Volume: 1646

    Topics: Animals; CA1 Region, Hippocampal; Cognitive Dysfunction; Encephalitis; Finasteride; Genetic Vectors; Lentivirus; Lipopolysaccharides; Male; Maze Learning; Mice; Mice, Inbred C57BL; Pregnanolone; Progesterone; Receptors, GABA; Up-Regulation

2016
Allopregnanolone treatment delays cholesterol accumulation and reduces autophagic/lysosomal dysfunction and inflammation in Npc1-/- mouse brain.
    Brain research, 2009, May-13, Volume: 1270

    Topics: Anesthetics; Animals; Astrocytes; Autophagy; Cholesterol; Disease Models, Animal; Encephalitis; Intracellular Signaling Peptides and Proteins; Lysosomes; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Microglia; Myelin Sheath; Neurons; Niemann-Pick C1 Protein; Niemann-Pick Disease, Type C; Pregnanolone; Proteins

2009
Impaired neurosteroid synthesis in multiple sclerosis.
    Brain : a journal of neurology, 2011, Volume: 134, Issue:Pt 9

    Topics: 20-Hydroxysteroid Dehydrogenases; Anesthetics; Animals; Cells, Cultured; Computational Biology; Encephalitis; Encephalomyelitis, Autoimmune, Experimental; Humans; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Multiple Sclerosis; Neurotransmitter Agents; Oligodendroglia; Pregnanolone; Rats; Rats, Sprague-Dawley

2011
Progesterone and allopregnanolone reduce inflammatory cytokines after traumatic brain injury.
    Experimental neurology, 2004, Volume: 189, Issue:2

    Topics: Animals; Brain Edema; Brain Injuries; Cytokines; Disease Models, Animal; Down-Regulation; Drug Administration Schedule; Encephalitis; Gene Expression; Interleukin-1; Male; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Reaction Time; RNA, Messenger; Treatment Outcome; Tumor Necrosis Factor-alpha

2004
Neurosteroids reduce inflammation after TBI through CD55 induction.
    Neuroscience letters, 2007, Sep-25, Volume: 425, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Brain Injuries; CD55 Antigens; Cell Death; Cerebral Cortex; Complement C3-C5 Convertases; Complement System Proteins; Encephalitis; Gliosis; Male; Neuroglia; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Steroids; Time Factors; Treatment Outcome

2007