pregnanolone has been researched along with Alcohol Drinking in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (6.45) | 18.2507 |
| 2000's | 12 (38.71) | 29.6817 |
| 2010's | 17 (54.84) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bartolomé, I; Darbra, S; Llidó, A; Pallarès, M | 3 |
| Beattie, MC; Daunais, JB; Grant, KA; Morrow, AL; Porcu, P; Reguyal, CS | 1 |
| Biggio, F; Boero, G; Ciarlo, B; Grayson, DR; Locci, V; Pisu, MG; Serra, M; Talani, G | 1 |
| DeLarge, AF; Erwin, LL; Nilges, MR; Weed, PF; Winsauer, PJ | 1 |
| Finn, DA; Ford, MM; Phillips, TJ; Ramaker, MJ; Strong-Kaufman, MN | 1 |
| Beadles-Bohling, A; Cozzoli, DK; Finn, DA; Ford, MM; Hertzberg, A; Tanchuck-Nipper, MA | 1 |
| Finn, DA; Ford, MM; Kaufman, MN; Nickel, JD | 1 |
| Cozzoli, DK; Finn, DA; Horowitz, CB; Kaufman, MN; Tanchuck-Nipper, MA | 1 |
| Amato, RJ; Hulin, MW; Lawrence, MN; Weed, PF; Winsauer, PJ | 1 |
| Cabrera, R; Estrella, CR; García, S; Lara, HE; Yunes, R | 1 |
| Finn, DA; Ford, MM; Fretwell, A; Strong, MN; Tanchuck, M; Yoneyama, N | 1 |
| Gurkovskaya, OV; Leonard, ST; Lewis, PB; Winsauer, PJ | 1 |
| Beckley, EH; Finn, DA; Ford, MM; Kaufman, KR | 1 |
| Ashenhurst, JR; Hutchison, KE; Morrow, AL; Ray, LA | 1 |
| Dore, R; Maciocco, E; Mostallino, MC; Pisu, MG; Secci, PP; Serra, M | 1 |
| Finn, DA; Ford, MM; Fretwell, AM; Ramaker, MJ | 1 |
| Finn, DA; Ford, MM; Ramaker, MJ; Strong, MN | 1 |
| Janak, PH; Michael Gill, T | 1 |
| Finn, DA; Ford, MM; Long, SL; Phillips, TJ; Sinnott, RS; Tanchuck, MA | 1 |
| De Almeida, RM; Debold, JF; Faccidomo, S; Fish, EW; Miczek, KA | 1 |
| Martín-García, E; Pallarès, M | 1 |
| Finn, DA; Ford, MM; Nickel, JD; Phillips, TJ | 1 |
| Finn, DA; Ford, MM; Nickel, JD | 1 |
| Darbra, S; Martin-García, E; Pallarès, M | 1 |
| Finn, DA; Ford, MM; Mark, GP; Nickel, JD; Phillips, TJ | 1 |
| Beckley, EH; Eddy, S; Finn, DA; Ford, MM; Nickel, JD | 1 |
| Janak, PH; Redfern, JE; Samson, HH | 1 |
| Bowen, CA; Grant, KA; Purdy, RH | 1 |
| Ehlers, CL; Li, TK; Purdy, RH; Slawecki, CJ; Walpole, T | 1 |
1 review(s) available for pregnanolone and Alcohol Drinking
| Article | Year |
|---|---|
Manipulation of GABAergic steroids: Sex differences in the effects on alcohol drinking- and withdrawal-related behaviors.
Topics: Alcohol Drinking; Alcoholism; Animals; Disease Models, Animal; Female; GABA Agonists; GABA-A Receptor Agonists; Male; Mice; Pregnanolone; Rats; Receptors, GABA-A; Reinforcement, Psychology; Sex Characteristics; Sex Factors; Substance Withdrawal Syndrome | 2010 |
1 trial(s) available for pregnanolone and Alcohol Drinking
| Article | Year |
|---|---|
Naltrexone selectively elevates GABAergic neuroactive steroid levels in heavy drinkers with the Asp40 allele of the OPRM1 gene: a pilot investigation.
Topics: Adult; Alcohol Drinking; Alcoholism; Alleles; Amino Acid Substitution; Aspartic Acid; Double-Blind Method; Female; gamma-Aminobutyric Acid; Humans; Male; Naltrexone; Pilot Projects; Polymorphism, Single Nucleotide; Pregnanolone; Receptors, Opioid, mu; Young Adult | 2010 |
29 other study(ies) available for pregnanolone and Alcohol Drinking
| Article | Year |
|---|---|
Effects of neonatal and adolescent neuroactive steroid manipulation on locomotor activity induced by ethanol in male wistar rats.
Topics: 5-alpha Reductase Inhibitors; Alcohol Drinking; Animals; Animals, Newborn; Anti-Anxiety Agents; Anxiety; Ethanol; Exploratory Behavior; Finasteride; Locomotion; Male; Neurotransmitter Agents; Pregnanolone; Progesterone; Rats; Rats, Wistar | 2017 |
Neuroactive Steroid (3α,5α)3-hydroxypregnan-20-one (3α,5α-THP) and Pro-inflammatory Cytokine MCP-1 Levels in Hippocampus CA1 are Correlated with Voluntary Ethanol Consumption in Cynomolgus Monkey.
Topics: Alcohol Drinking; Animals; Biomarkers; CA1 Region, Hippocampal; Chemokine CCL2; Macaca fascicularis; Pregnanolone | 2018 |
Low doses of prenatal ethanol exposure and maternal separation alter HPA axis function and ethanol consumption in adult male rats.
Topics: Alcohol Drinking; Analysis of Variance; Animals; Anxiety; Corticosterone; Electroshock; Fetal Alcohol Spectrum Disorders; Male; Maternal Deprivation; Pregnanolone; Random Allocation; Rats, Sprague-Dawley; Stress, Psychological | 2018 |
Early post-natal neuroactive steroid manipulation modulates ondansetron effects on initial periods of alcohol consumption in rats.
Topics: Alcohol Drinking; Animals; Dose-Response Relationship, Drug; Exploratory Behavior; Finasteride; Male; Neurotransmitter Agents; Ondansetron; Pregnanolone; Rats | 2018 |
Effects of noncontingent ethanol, DHEA, and pregnanolone administration on ethanol self-administration in outbred female rats.
Topics: Alcohol Drinking; Animals; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Ethanol; Female; Pregnanolone; Rats; Rats, Long-Evans; Reinforcement Schedule; Self Administration; Treatment Outcome | 2019 |
Effect of nucleus accumbens shell infusions of ganaxolone or gaboxadol on ethanol consumption in mice.
Topics: Alcohol Drinking; Animals; Ethanol; GABA-A Receptor Agonists; Infusions, Intraventricular; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Pregnanolone; Receptors, GABA-A; Treatment Outcome | 2015 |
Sex Differences in Ethanol's Anxiolytic Effect and Chronic Ethanol Withdrawal Severity in Mice with a Null Mutation of the 5α-Reductase Type 1 Gene.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Alcohol Drinking; Animals; Anti-Anxiety Agents; Behavior, Animal; Corticosterone; Ethanol; Female; Gene Deletion; Genotype; Male; Maze Learning; Membrane Proteins; Mice; Mice, Knockout; Mutation; Pregnanolone; Sex Characteristics; Sex Factors; Substance Withdrawal Syndrome | 2015 |
Null mutation of 5α-reductase type I gene alters ethanol consumption patterns in a sex-dependent manner.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Alcohol Drinking; Alleles; Animals; Biopsy; Ethanol; Female; Finasteride; Genotype; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Pregnanolone; Receptors, GABA-A; Recombination, Genetic; Saccharin; Sex Factors; Steroids | 2015 |
Environmental stressors influence limited-access ethanol consumption by C57BL/6J mice in a sex-dependent manner.
Topics: Alcohol Drinking; Animals; Corticosterone; Environment; Female; Male; Mice; Mice, Inbred C57BL; Pregnanolone; Sex Characteristics; Stress, Psychological | 2014 |
Comparison of dehydroepiandrosterone (DHEA) and pregnanolone with existing pharmacotherapies for alcohol abuse on ethanol- and food-maintained responding in male rats.
Topics: Acamprosate; Alcohol Drinking; Alcoholism; Animals; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Eating; Ethanol; Male; Naltrexone; Pregnanolone; Rats; Rats, Long-Evans; Self Administration; Taurine | 2015 |
Postnatal administration of allopregnanolone modifies glutamate release but not BDNF content in striatum samples of rats prenatally exposed to ethanol.
Topics: Alcohol Drinking; Animals; Brain-Derived Neurotrophic Factor; Corpus Striatum; Ethanol; Female; Glutamic Acid; Male; Pregnancy; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2015 |
Effects of neonatal allopregnanolone manipulations and early maternal separation on adult alcohol intake and monoamine levels in ventral striatum of male rats.
Topics: 5-alpha Reductase Inhibitors; Aging; Alcohol Drinking; Animals; Animals, Newborn; Biogenic Monoamines; Ethanol; Exploratory Behavior; Female; Hippocampus; Male; Maternal Deprivation; Pregnanolone; Rats; Rats, Wistar; Ventral Striatum | 2016 |
Inhibition of 5alpha-reduced steroid biosynthesis impedes acquisition of ethanol drinking in male C57BL/6J mice.
Topics: Alcohol Drinking; Alcoholism; Animals; Behavior, Animal; Cholestenone 5 alpha-Reductase; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Finasteride; Male; Mice; Mice, Inbred C57BL; Pregnanolone; Receptors, GABA-A; Time Factors | 2008 |
Effects of pregnanolone and dehydroepiandrosterone on ethanol intake in rats administered ethanol or saline during adolescence.
Topics: Age Factors; Alcohol Drinking; Animals; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Ethanol; Male; Pregnanolone; Rats; Rats, Long-Evans; Sodium Chloride | 2009 |
Effects of voluntary ethanol consumption on emotional state and stress responsiveness in socially isolated rats.
Topics: Alcohol Drinking; Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking; Electroshock; Emotions; Ethanol; Male; Maze Learning; Pregnanolone; Rats; Rats, Sprague-Dawley; Social Isolation; Stress, Psychological | 2011 |
Alteration of ethanol drinking in mice via modulation of the GABA(A) receptor with ganaxolone, finasteride, and gaboxadol.
Topics: Alcohol Drinking; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drinking Behavior; Finasteride; GABA-A Receptor Agonists; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Models, Animal; Pregnanolone; Receptors, GABA-A | 2011 |
Effect of ganaxolone and THIP on operant and limited-access ethanol self-administration.
Topics: Alcohol Deterrents; Alcohol Drinking; Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Drugs, Investigational; Ethanol; GABA-A Receptor Agonists; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Molecular Targeted Therapy; Nootropic Agents; Pregnanolone; Protein Subunits; Receptors, GABA-A; Reinforcement, Psychology; Self Administration; Time Factors | 2012 |
Comparison of the effects of allopregnanolone with direct GABAergic agonists on ethanol self-administration with and without concurrently available sucrose.
Topics: Alcohol Drinking; Animals; Baclofen; Central Nervous System Depressants; Conditioning, Operant; Dose-Response Relationship, Drug; Ethanol; GABA Agonists; Male; Muscimol; Pregnanolone; Rats; Rats, Long-Evans; Reinforcement, Psychology; Sucrose | 2003 |
Sex differences in the effect of ethanol injection and consumption on brain allopregnanolone levels in C57BL/6 mice.
Topics: Alcohol Drinking; Animals; Behavior, Animal; Brain; Brain Chemistry; Central Nervous System Depressants; Chromatography, Gas; Corticosterone; Dose-Response Relationship, Drug; Drug Administration Routes; Ethanol; Female; Injections; Male; Mice; Mice, Inbred C57BL; Pregnanolone; Radioimmunoassay; Sex Characteristics | 2004 |
Role of alcohol consumption in escalation to violence.
Topics: Aggression; Alcohol Drinking; Analgesics, Non-Narcotic; Ethanol; Female; Humans; Male; Oxazolidinones; Piperidines; Pregnanolone; Pyridines; Receptors, GABA; Receptors, Serotonin; Tryptamines; Violence | 2004 |
Intrahippocampal nicotine and neurosteroids effects on the anxiety-like behaviour in voluntary and chronic alcohol-drinking rats.
Topics: Administration, Oral; Alcohol Drinking; Animals; Anti-Anxiety Agents; Anxiety; Drug Interactions; Ethanol; Exploratory Behavior; GABA Agents; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Hippocampus; Male; Microinjections; Motor Activity; Nicotine; Nicotinic Agonists; Pregnanolone; Pregnenolone; Random Allocation; Rats; Rats, Wistar; Receptors, GABA-A; Self Medication | 2005 |
Neurosteroid modulators of GABA(A) receptors differentially modulate Ethanol intake patterns in male C57BL/6J mice.
Topics: Alcohol Drinking; Animals; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Pregnanolone; Receptors, GABA-A; Time Factors | 2005 |
Treatment with and withdrawal from finasteride alter ethanol intake patterns in male C57BL/6J mice: potential role of endogenous neurosteroids?
Topics: Alcohol Drinking; Animals; Drinking; Enzyme Inhibitors; Ethanol; Finasteride; Male; Mice; Mice, Inbred C57BL; Pregnanolone; Receptors, GABA-A; Self Administration; Steroids | 2005 |
Intrahippocampal allopregnanolone decreases voluntary chronic alcohol consumption in non-selected rats.
Topics: Alcohol Drinking; Alcohols; Anesthetics; Animals; Behavior, Animal; Choice Behavior; Conditioning, Operant; Dose-Response Relationship, Drug; Drinking Behavior; Food Deprivation; Glucose; Hippocampus; Linear Models; Male; Pregnanolone; Pregnenolone; Rats; Rats, Wistar | 2007 |
Allopregnanolone influences the consummatory processes that govern ethanol drinking in C57BL/6J mice.
Topics: Alcohol Drinking; Analysis of Variance; Animals; Conditioning, Operant; Consummatory Behavior; Ethanol; GABA Modulators; Injections, Intraventricular; Male; Mice; Mice, Inbred C57BL; Motor Activity; Pregnanolone; Receptors, GABA-A; Reinforcement, Psychology; Self Administration | 2007 |
Ethanol intake patterns in female mice: influence of allopregnanolone and the inhibition of its synthesis.
Topics: Alcohol Drinking; Animals; Brain Chemistry; Central Nervous System Depressants; Dose-Response Relationship, Drug; Drinking Behavior; Enzyme Inhibitors; Ethanol; Female; Finasteride; Mice; Mice, Inbred C57BL; Pregnanolone | 2008 |
The reinforcing effects of ethanol are altered by the endogenous neurosteroid, allopregnanolone.
Topics: Alcohol Drinking; Alcoholism; Animals; Conditioning, Operant; Male; Motivation; Pregnanolone; Rats; Rats, Long-Evans; Receptors, GABA; Reinforcement Schedule; Self Administration | 1998 |
An investigation of endogenous neuroactive steroid-induced modulation of ethanol's discriminative stimulus effects.
Topics: Alcohol Drinking; Animals; Brain; Discrimination Learning; Dose-Response Relationship, Drug; Male; Pregnanolone; Rats; Rats, Long-Evans; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 1999 |
Effects of allopregnanolone on the EEG of alcohol-preferring and alcohol-nonpreferring rats.
Topics: Alcohol Drinking; Amygdala; Animals; Cerebral Cortex; Electroencephalography; Male; Pregnanolone; Rats | 2000 |