Page last updated: 2024-08-23

pregnanolone and Aggression

pregnanolone has been researched along with Aggression in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (64.71)29.6817
2010's4 (23.53)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Bäckström, T; Bengtsson, SKS; Ekberg, K; Johansson, M; Lundgren, P; Malinina, E; Ragagnin, G; Sjöstedt, J1
Comasco, E; Dubol, M; Fisher, PM; Frokjaer, VG; Hustad, S; Kaltsouni, E; Lanzenberger, R; Sundström-Poromaa, I; Wikström, J1
Bäckström, T; Bengtsson, SK; Johansson, M; Löfgren, M1
Berretti, R; Calza, A; Choleris, E; Concas, A; Locci, A; Porcu, P; Santoru, F; Sogliano, C1
Frye, CA; Rhodes, ME1
Nelson, M; Pinna, G1
De Almeida, RM; De Bold, JF; Fish, EW; Miczek, KA1
De Bold, JF; Fish, EW; Miczek, KA1
Costa, E; Dong, E; Guidotti, A; Matsumoto, K; Pinna, G1
Agis-Balboa, RC; Costa, E; Doueiri, MS; Guidotti, A; Pinna, G1
Costa, E; Guidotti, A; Pinna, G1
De Almeida, RM; Debold, JF; Faccidomo, S; Fish, EW; Miczek, KA1
Carboni, G; Nelson, M; Pibiri, F; Pinna, G1
Agis-Balboa, RC; Costa, E; Guidotti, A; Nelson, M; Pibiri, F; Pinna, G1
Chodounská, H; Kasal, A; Kohout, L; Krsiak, M; Slavíková, B; Uhlírová, L1
DeBold, JF; Faccidomo, S; Fish, EW; Miczek, KA1
Engel, SR; Grant, KA1

Reviews

4 review(s) available for pregnanolone and Aggression

ArticleYear
Social and neural determinants of aggressive behavior: pharmacotherapeutic targets at serotonin, dopamine and gamma-aminobutyric acid systems.
    Psychopharmacology, 2002, Volume: 163, Issue:3-4

    Topics: Adaptation, Psychological; Aggression; Animals; Brain; Dopamine; Ethanol; gamma-Aminobutyric Acid; Gonadal Steroid Hormones; Humans; Oxazolidinones; Piperidines; Pregnanolone; Pyridines; Receptors, Dopamine; Receptors, GABA; Receptors, Serotonin; Reinforcement Schedule; Serotonin; Serotonin Receptor Agonists; Social Environment; Tryptamines

2002
Brain neurosteroids in gender-related aggression induced by social isolation.
    Critical reviews in neurobiology, 2004, Volume: 16, Issue:1-2

    Topics: Aggression; Animals; Female; GABA Agents; Gonadal Steroid Hormones; Male; Methionine; Mice; Neurotransmitter Agents; Pregnanolone; Reelin Protein; Sex Characteristics; Social Isolation; Steroids; Valproic Acid

2004
Neurosteroid biosynthesis regulates sexually dimorphic fear and aggressive behavior in mice.
    Neurochemical research, 2008, Volume: 33, Issue:10

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Aggression; Anabolic Agents; Androstanes; Animals; Behavior, Animal; Down-Regulation; Fear; Female; Fluoxetine; Frontal Lobe; Male; Mice; Muscle, Skeletal; Nandrolone; Organ Size; Pregnanolone; Receptors, GABA-A; RNA, Messenger; Social Isolation; Stanozolol; Stereotyped Behavior; Synaptic Transmission; Testosterone Propionate

2008
Neurosteroids and behavior.
    International review of neurobiology, 2001, Volume: 46

    Topics: Aggression; Animals; Anxiety; Behavior, Animal; Brain Chemistry; Dehydroepiandrosterone; Humans; Pregnanolone; Progesterone

2001

Trials

1 trial(s) available for pregnanolone and Aggression

ArticleYear
Brain reactivity during aggressive response in women with premenstrual dysphoric disorder treated with a selective progesterone receptor modulator.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2021, Volume: 46, Issue:8

    Topics: Aggression; Brain; Female; Humans; Luteal Phase; Pregnanolone; Premenstrual Dysphoric Disorder; Progesterone; Receptors, Progesterone

2021

Other Studies

12 other study(ies) available for pregnanolone and Aggression

ArticleYear
Isoallopregnanolone Inhibits Estrus Cycle-Dependent Aggressive Behavior.
    Biomolecules, 2023, 06-20, Volume: 13, Issue:6

    Topics: Aggression; Animals; Estrus; Female; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A

2023
Allopregnanolone promotes success in food competition in subordinate male rats.
    Neuropsychobiology, 2013, Volume: 68, Issue:1

    Topics: Administration, Intravenous; Aggression; Animals; Anti-Anxiety Agents; Body Weight; Competitive Behavior; Dose-Response Relationship, Drug; Feeding Behavior; Hierarchy, Social; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Pregnanolone; Rats; Rats, Wistar; Steroids; Testosterone; Time Factors

2013
Neonatal exposure to estradiol decreases hypothalamic allopregnanolone concentrations and alters agonistic and sexual but not affective behavior in adult female rats.
    Hormones and behavior, 2014, Volume: 65, Issue:2

    Topics: Aggression; Animals; Anxiety; Behavior, Animal; Estradiol; Exploratory Behavior; Female; Hypothalamus; Motor Activity; Pregnanolone; Rats; Rats, Sprague-Dawley; Sexual Behavior, Animal; Social Behavior

2014
Fluoxetine-induced decrements in sexual responses of female rats and hamsters are reversed by 3α,5α-THP.
    The journal of sexual medicine, 2010, Volume: 7, Issue:8

    Topics: Aggression; Animals; Antidepressive Agents, Second-Generation; Brain Mapping; Cricetinae; Female; Fluoxetine; Injections; Injections, Intraperitoneal; Injections, Subcutaneous; Pregnanolone; Rats; Sexual Behavior, Animal; Ventral Tegmental Area

2010
S-norfluoxetine microinfused into the basolateral amygdala increases allopregnanolone levels and reduces aggression in socially isolated mice.
    Neuropharmacology, 2011, Volume: 60, Issue:7-8

    Topics: Aggression; Amygdala; Animals; Behavior, Animal; Corpus Striatum; Fluoxetine; Locomotion; Male; Mice; Pregnanolone; Selective Serotonin Reuptake Inhibitors; Social Isolation

2011
Aggressive behavior as a reinforcer in mice: activation by allopregnanolone.
    Psychopharmacology, 2002, Volume: 163, Issue:3-4

    Topics: Aggression; Animals; Behavior, Animal; Conditioning, Operant; Dose-Response Relationship, Drug; Extinction, Psychological; Gonadal Steroid Hormones; Male; Mice; Mice, Inbred Strains; Motor Activity; Pregnanolone; Reinforcement Schedule; Reinforcement, Psychology; Time Factors

2002
In socially isolated mice, the reversal of brain allopregnanolone down-regulation mediates the anti-aggressive action of fluoxetine.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Feb-18, Volume: 100, Issue:4

    Topics: Aggression; Animals; Brain; Down-Regulation; Female; Fluoxetine; Male; Mice; Pregnanolone; Selective Serotonin Reuptake Inhibitors; Social Isolation; Stereoisomerism

2003
Changes in brain testosterone and allopregnanolone biosynthesis elicit aggressive behavior.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Feb-08, Volume: 102, Issue:6

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Aggression; Animals; Behavior; Brain; Estrogens; Female; Fluoxetine; Humans; Male; Mice; Motor Activity; Orchiectomy; Ovariectomy; Pregnanolone; Progesterone; Receptors, GABA-A; Testosterone

2005
Role of alcohol consumption in escalation to violence.
    Annals of the New York Academy of Sciences, 2004, Volume: 1036

    Topics: Aggression; Alcohol Drinking; Analgesics, Non-Narcotic; Ethanol; Female; Humans; Male; Oxazolidinones; Piperidines; Pregnanolone; Pyridines; Receptors, GABA; Receptors, Serotonin; Tryptamines; Violence

2004
Neurosteroids regulate mouse aggression induced by anabolic androgenic steroids.
    Neuroreport, 2006, Oct-02, Volume: 17, Issue:14

    Topics: Aggression; Androgens; Anesthetics; Animals; Behavior, Animal; Brain; Brain Chemistry; Dose-Response Relationship, Drug; Drug Interactions; Female; Fluoxetine; Gene Expression Regulation; Male; Mice; Motor Activity; Pregnanolone; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin; Sex Factors; Social Isolation; Testosterone; Time Factors

2006
Suppressing aggressive behavior with analogs of allopregnanolone (epalon).
    Steroids, 2001, Volume: 66, Issue:2

    Topics: Aggression; Animals; Male; Mice; Mice, Inbred ICR; Pregnanolone

2001
Alcohol, allopregnanolone and aggression in mice.
    Psychopharmacology, 2001, Volume: 153, Issue:4

    Topics: Aggression; Anesthetics; Animals; Central Nervous System Depressants; Dose-Response Relationship, Drug; Ethanol; Female; Male; Mice; Pregnanediones; Pregnanolone

2001