Page last updated: 2024-08-23

pregnanolone and Absence Status

pregnanolone has been researched along with Absence Status in 16 studies

Research

Studies (16)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (6.25)	29.6817
2010's	8 (50.00)	24.3611
2020's	7 (43.75)	2.80

Authors

Authors	Studies
Aimetti, A; Gasior, M; Husain, AM; Ramsay, RE; Swisher, CB; Vaitkevicius, H	1
Biagini, G; Costa, AM; Gol, M; Lucchi, C	1
Aleman, M; Bruun, DA; Chen, YJ; Lein, PJ; Ma, B; Rogawski, MA; Smiley-Jewell, SM; Wu, CY; Zolkowska, D	1
Biagini, G; Costa, AM; Lucchi, C; Rustichelli, C	1
Bruun, DA; Calsbeek, J; Dhir, A; González, E; Guignet, M; Harvey, DJ; Lein, PJ; Rogawski, MA; Saito, N; Tancredi, DJ; Tsai, YH; Vu, J	1
Biagini, G; Costa, AM; Lucchi, C; Messina, S; Rustichelli, C; Senn, L	1
Lattanzi, S; Riva, A; Striano, P	1
Claassen, J; Colquhoun, H; Doherty, JJ; Hoffmann, E; Husain, AM; Kanes, SJ; Raines, S; Rosenthal, ES; Vaitkevicius, H; Wainwright, MS	1
Cho, I; Cho, YJ; Heo, K; Kim, HW; Kim, WJ; Lee, BI	1
Bedin, R; Biagini, G; Giovannini, G; Lucchi, C; Meletti, S; Monti, G; Rustichelli, C; Trenti, T	2
Barker-Haliski, M; DiCamillo, A; Gruner, JA; Hinchliffe, R; Saporito, MS; White, HS	1
Carver, CM; Clossen, B; Reddy, DS; Wu, X	1
Lossin, C; Loya, CM; Reddy, K; Rogawski, MA; Zolkowska, D	1
Broomall, E; Chang, C; Goldstein, J; Grimason, M; Kanes, S; Natale, JE; Rogawski, MA; Smith, CM; Wainwright, MS	1
Keller, AF; Leroy, C; Nehlig, A; Poisbeau, P	1

Reviews

1 review(s) available for pregnanolone and Absence Status

Article	Year
Neuroactive steroids for the treatment of status epilepticus. Epilepsia, 2013, Volume: 54 Suppl 6 Topics: Anesthetics; Animals; Benzodiazepines; Diazepam; Humans; Neurotransmitter Agents; Pregnanolone; Status Epilepticus	2013

Trials

2 trial(s) available for pregnanolone and Absence Status

Article	Year
Intravenous ganaxolone for the treatment of refractory status epilepticus: Results from an open-label, dose-finding, phase 2 trial. Epilepsia, 2022, Volume: 63, Issue:9 Topics: Anesthetics; Anticonvulsants; Benzodiazepines; Humans; Neurosteroids; Pregnanolone; Status Epilepticus	2022
Brexanolone as adjunctive therapy in super-refractory status epilepticus. Annals of neurology, 2017, Volume: 82, Issue:3 Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Female; Humans; Male; Middle Aged; Pregnanolone; Recurrence; Retrospective Studies; Status Epilepticus; Treatment Outcome; Young Adult	2017

Other Studies

13 other study(ies) available for pregnanolone and Absence Status

Article	Year
Antiepileptogenic effects of trilostane in the kainic acid model of temporal lobe epilepsy. Epilepsia, 2023, Volume: 64, Issue:5 Topics: Animals; Epilepsy, Temporal Lobe; Kainic Acid; Neurosteroids; Pregnanolone; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus	2023
Tolerability and pharmacokinetics of intravenous allopregnanolone with and without midazolam pretreatment in two healthy dogs. Epilepsia open, 2023, Volume: 8, Issue:2 Topics: Administration, Intravenous; Animals; Dogs; Midazolam; Pregnanolone; Status Epilepticus	2023
Allopregnanolone and Pregnanolone Are Reduced in the Hippocampus of Epileptic Rats, but Only Allopregnanolone Correlates with Seizure Frequency. Neuroendocrinology, 2021, Volume: 111, Issue:6 Topics: Animals; Disease Models, Animal; Electrocorticography; Epilepsy; Hippocampus; Male; Neocortex; Pregnanolone; Rats; Rats, Sprague-Dawley; Status Epilepticus	2021
Allopregnanolone and perampanel as adjuncts to midazolam for treating diisopropylfluorophosphate-induced status epilepticus in rats. Annals of the New York Academy of Sciences, 2020, Volume: 1480, Issue:1 Topics: Animals; Behavior, Animal; Drug Therapy, Combination; Electroencephalography; Isoflurophate; Male; Midazolam; Nitriles; Pregnanolone; Pyridones; Rats; Rats, Sprague-Dawley; Status Epilepticus	2020
Augmentation of endogenous neurosteroid synthesis alters experimental status epilepticus dynamics. Epilepsia, 2020, Volume: 61, Issue:9 Topics: 5-alpha-Dihydroprogesterone; Animals; Brain; Chromatography, Liquid; Dihydrotestosterone; Electrocorticography; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Neocortex; Neurosteroids; Pregnanolone; Pregnenolone; Progesterone; Rats; Receptors, GABA-A; Status Epilepticus; Tandem Mass Spectrometry; Time Factors	2020
Ganaxolone treatment for epilepsy patients: from pharmacology to place in therapy. Expert review of neurotherapeutics, 2021, Volume: 21, Issue:11 Topics: Anticonvulsants; Child; Epilepsy; Humans; Pregnanolone; Status Epilepticus	2021
Increased Superoxide Dismutase 2 by Allopregnanolone Ameliorates ROS-Mediated Neuronal Death in Mice with Pilocarpine-Induced Status Epilepticus. Neurochemical research, 2018, Volume: 43, Issue:7 Topics: Animals; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Pilocarpine; Pregnanolone; Reactive Oxygen Species; Status Epilepticus; Superoxide Dismutase	2018
Low levels of progesterone and derivatives in cerebrospinal fluid of patients affected by status epilepticus. Journal of neurochemistry, 2018, Volume: 147, Issue:2 Topics: 5-alpha-Dihydroprogesterone; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Pregnanolone; Pregnenolone; Progesterone; Retrospective Studies; Status Epilepticus; Steroids; Tandem Mass Spectrometry; Young Adult	2018
Intravenously Administered Ganaxolone Blocks Diazepam-Resistant Lithium-Pilocarpine-Induced Status Epilepticus in Rats: Comparison with Allopregnanolone. The Journal of pharmacology and experimental therapeutics, 2019, Volume: 368, Issue:3 Topics: Administration, Intravenous; Anesthetics; Animals; Anticonvulsants; Diazepam; Drug Resistant Epilepsy; Electroencephalography; Lithium; Male; Muscarinic Agonists; Pilocarpine; Pregnanolone; Rats; Rats, Sprague-Dawley; Status Epilepticus	2019
Extrasynaptic γ-aminobutyric acid type A receptor-mediated sex differences in the antiseizure activity of neurosteroids in status epilepticus and complex partial seizures. Epilepsia, 2019, Volume: 60, Issue:4 Topics: Animals; Brain; Female; Male; Mice; Mice, Inbred C57BL; Neurosteroids; Pregnanolone; Receptors, GABA-A; Seizures; Sex Characteristics; Status Epilepticus	2019
Pediatric super-refractory status epilepticus treated with allopregnanolone. Annals of neurology, 2014, Volume: 76, Issue:6 Topics: Child; Child, Preschool; Female; Humans; Pregnanolone; Status Epilepticus; Treatment Outcome	2014
Decreased allopregnanolone levels in cerebrospinal fluid obtained during status epilepticus. Epilepsia, 2017, Volume: 58, Issue:2 Topics: Adolescent; Adult; Aged; Child; Chromatography, High Pressure Liquid; Chromatography, Liquid; Electroencephalography; Female; Humans; Male; Mass Spectrometry; Middle Aged; Pregnanolone; Retrospective Studies; Status Epilepticus; Young Adult	2017
Pharmacological plasticity of GABA(A) receptors at dentate gyrus synapses in a rat model of temporal lobe epilepsy. The Journal of physiology, 2004, Jun-01, Volume: 557, Issue:Pt 2 Topics: Animals; Anticonvulsants; Dentate Gyrus; Diazepam; Disease Models, Animal; Electric Conductivity; Epilepsy, Temporal Lobe; Flumazenil; GABA Modulators; Lithium; Male; Neural Inhibition; Patch-Clamp Techniques; Pilocarpine; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Status Epilepticus; Synapses	2004