pregnanetriolone has been researched along with Cushing-Syndrome* in 2 studies
1 review(s) available for pregnanetriolone and Cushing-Syndrome
Article | Year |
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[Abnormal steroid hormone production (in children)--special reference to microanalysis of urinary steroids by glass capillary gas chromatography and its application].
Topics: Adrenal Gland Neoplasms; Age Factors; Child; Chromatography, Gas; Cushing Syndrome; Evaluation Studies as Topic; Hormones; Humans; Male; Mixed Function Oxygenases; Pregnanetriol | 1982 |
1 other study(ies) available for pregnanetriolone and Cushing-Syndrome
Article | Year |
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Pregnanetriolone, a normal steroid metabolite: its excretion by normal, Cushing's syndrome and congenital adrenal hyperplasia subjects.
Synthesis of 3H-pregnanetriolone permitted the estimation of pregnanetriolone in urine with a sensitivity in excess of most previous claims. A good correlation (r = +0.97) was obtained between the values from gas liquid chromatography and those of a double isotope derivative method. In contrast to previous reports, these methods indicated that pregnanetriolone is excreted by normal adults. Urinary pregnanetriolone levels were 18-59 mug/24hr for normal subjects, 35-290mug/24hr in Cushing's syndrome and 250-7000 mug/24hr with congenital adrenal hyperplasia. It is concluded that pregnanetriolone is a normal steroid metabolite and its occurrence in Cushing's syndrome does not necessary indicate an abnormal steroid biosynthetic pathway. Topics: Adrenal Gland Diseases; Adult; Chromatography; Chromatography, Gas; Crystallization; Cushing Syndrome; Female; Humans; Hyperplasia; Infant; Ketosteroids; Male; Pregnanetriol | 1976 |