Compounds > pregna-4-17-diene-3-16-dione--(17z)-isomer

pregna-4-17-diene-3-16-dione--(17z)-isomer and Pancreatic-Neoplasms

pregna-4-17-diene-3-16-dione--(17z)-isomer has been researched along with Pancreatic-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for pregna-4-17-diene-3-16-dione--(17z)-isomer and Pancreatic-Neoplasms

ArticleYear
Synthesis of guggulsterone derivatives as potential anti-austerity agents against PANC-1 human pancreatic cancer cells.
    Bioorganic & medicinal chemistry letters, 2020, 04-01, Volume: 30, Issue:7

    E- and Z-guggulsterones and nine guggulsterone derivatives (GSDs) were synthesized and evaluated for their preferential cytotoxicity against human PANC-1 cell in nutrient deprived medium utilizing antiausterity strategy. Among the synthesized compounds, GSD-1 and GSD-7 showed potent cytotoxicity against PANC-1 cells under nutrient-deprived conditions in a concentration dependent manner, with a PC

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Pancreatic Neoplasms; Pregnenediones; Structure-Activity Relationship

2020