pregabalin and Lymphoma--Large-B-Cell--Diffuse

pregabalin has been researched along with Lymphoma--Large-B-Cell--Diffuse* in 1 studies

Other Studies

1 other study(ies) available for pregabalin and Lymphoma--Large-B-Cell--Diffuse

Article	Year
[A case of neurotoxicity reduced with pregabalin in R-CHOP chemotherapy for diffuse large B-cell lymphoma]. Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:5 When performing R-CHOP(rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone)for diffuse large B-cell lymphoma(DLBCL), neurotoxicity of vincristine(VCR)is the serious dose-limiting factor.Pregabalin is one of the first-line treatments for painful diabetic peripheral neuropathy in many countries, and we have administered it to relieve the neurotoxicity associated with adverse effects of VCR in a DLBCL patient treated with the R-CHOP regimen.A 49-year-old man with kidney DLBCL had surgery performed.Afterward, the R-CHOP regimen was introduced.In order to relieve the neurotoxicity of VCR, pregabalin was used from day 8 in the second course.The severity of sensory neurotoxicity after the administration of pregabalin was improved from CTCAE(v4.0)grade 3 to grade 1.Therefore, there is a possibility that VCR-induced neurotoxicity is relieved by pregabalin.Further trials are needed to confirm the value of pregabalin. Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; gamma-Aminobutyric Acid; Humans; Kidney; Lymphoma, Large B-Cell, Diffuse; Male; Middle Aged; Neoplasm Staging; Peripheral Nervous System Diseases; Prednisone; Pregabalin; Rituximab; Tomography, X-Ray Computed; Vincristine	2012

Article

Year

[A case of neurotoxicity reduced with pregabalin in R-CHOP chemotherapy for diffuse large B-cell lymphoma].

Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:5

When performing R-CHOP(rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone)for diffuse large B-cell lymphoma(DLBCL), neurotoxicity of vincristine(VCR)is the serious dose-limiting factor.Pregabalin is one of the first-line treatments for painful diabetic peripheral neuropathy in many countries, and we have administered it to relieve the neurotoxicity associated with adverse effects of VCR in a DLBCL patient treated with the R-CHOP regimen.A 49-year-old man with kidney DLBCL had surgery performed.Afterward, the R-CHOP regimen was introduced.In order to relieve the neurotoxicity of VCR, pregabalin was used from day 8 in the second course.The severity of sensory neurotoxicity after the administration of pregabalin was improved from CTCAE(v4.0)grade 3 to grade 1.Therefore, there is a possibility that VCR-induced neurotoxicity is relieved by pregabalin.Further trials are needed to confirm the value of pregabalin.

Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; gamma-Aminobutyric Acid; Humans; Kidney; Lymphoma, Large B-Cell, Diffuse; Male; Middle Aged; Neoplasm Staging; Peripheral Nervous System Diseases; Prednisone; Pregabalin; Rituximab; Tomography, X-Ray Computed; Vincristine

2012