Page last updated: 2024-11-07

prednisone and Thrombophilia

prednisone has been researched along with Thrombophilia in 21 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Thrombophilia: A disorder of HEMOSTASIS in which there is a tendency for the occurrence of THROMBOSIS.

Research Excerpts

ExcerptRelevanceReference
"The therapeutic use of thalidomide in patients with multiple myeloma is often complicated by the development of venous thromboembolism."7.75Hypercoagulable states in patients with multiple myeloma can affect the thalidomide-associated venous thromboembolism. ( Claxton, D; Fink, LM; Ibrahim, S; Talamo, GP; Tricot, GJ; Zangari, M, 2009)
"Administration of prednisone to healthy Beagles resulted in hypercoagulability as indicated by TEG tracings, whereas the effect on TG was more variable."5.15Effect of prednisone administration on coagulation variables in healthy Beagle dogs. ( Allegret, V; Bédard, C; Dunn, ME; Rose, LJ, 2011)
"The therapeutic use of thalidomide in patients with multiple myeloma is often complicated by the development of venous thromboembolism."3.75Hypercoagulable states in patients with multiple myeloma can affect the thalidomide-associated venous thromboembolism. ( Claxton, D; Fink, LM; Ibrahim, S; Talamo, GP; Tricot, GJ; Zangari, M, 2009)
"Clinical management of warfarin therapy is complex, and dosing algorithms do not include genetic factors or interactions with other drugs for warfarin dose determinations."2.73Oral anticoagulation with warfarin is significantly influenced by steroids and CYP2C9 polymorphisms in children with cancer. ( Bergan, S; Holmstrøm, H; Ruud, E; Wesenberg, F, 2008)
"The risk of preeclampsia and placental insufficiency was substantial and occurred in 50% of patients."2.42Antiphospholipid syndrome in obstetrics. ( Heilmann, L; Pollow, K; von Tempelhoff, GF, 2003)
"In a group of newly diagnosed acute lymphocytic leukemia (ALL) children we evaluated a number of hemostatic and inflammatory markers at diagnosis and at different time points during chemotherapy for the remission induction to identify alterations in the plasma levels of prothrombotic markers before and during the course of chemotherapy."1.36Prospective study of hemostatic alterations in children with acute lymphoblastic leukemia. ( Altomare, M; Crescenzio, N; De Mattia, D; Del Vecchio, GC; Falanga, A; Giordano, P; Marchetti, M; Molinari, AC; Perutelli, P; Russo, G; Santoro, N; Saracco, P, 2010)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.76)18.2507
2000's10 (47.62)29.6817
2010's9 (42.86)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Sung, N1
Khan, SA1
Yiu, ME1
Jubiz, G1
Salazar, MD1
Skariah, A1
Dambaeva, S1
Kwak-Kim, J1
Brunet, BA1
Sugg, RM1
Stewart, P1
Geng, LN1
Conway, D1
Barnhart, S1
Nowatzky, J1
Kovacs, MJ1
Davies, GA1
Chapman, JA1
Bahlis, N1
Voralia, M1
Roy, J1
Kouroukis, CT1
Chen, C1
Belch, A1
Reece, D1
Zhu, L1
Meyer, RM1
Shepherd, L1
Stewart, KA1
Benadiba, J1
Robitaille, N1
Lambert, G1
Itaj, NK1
Pastore, Y1
Kurt-Şükür, ED1
Özçakar, ZB1
Fitöz, S1
Yilmaz, S1
Teber, S1
Ünal İnce, E1
Ekim, M1
Yalçinkaya, F1
Talamo, GP1
Ibrahim, S1
Claxton, D1
Tricot, GJ1
Fink, LM1
Zangari, M1
Giordano, P1
Molinari, AC1
Del Vecchio, GC1
Saracco, P1
Russo, G1
Altomare, M1
Perutelli, P1
Crescenzio, N1
Santoro, N1
Marchetti, M1
De Mattia, D1
Falanga, A1
Perez, MA1
Glaser, JS1
Schatz, NJ1
Bordel-Gómez, MT1
Zafra-Cobo, MI1
Cardeñoso-Álvarez, ME1
Sánchez-Estella, J1
Martín-Arribas, MI1
Rose, LJ1
Dunn, ME1
Allegret, V1
Bédard, C1
Heilmann, L1
von Tempelhoff, GF1
Pollow, K1
Martin, L1
Armingaud, P1
Georgescu, V1
Matre, F1
Legac, E1
Estève, E1
McLaurin, EY1
Holliday, SL1
Williams, P1
Brey, RL1
Hauser, AC1
Hauser, L1
Pabinger-Fasching, I1
Quehenberger, P1
Derfler, K1
Hörl, WH1
Veneri, D1
Ambrosetti, A1
Franchini, M1
Mosna, F1
Poli, G1
Pizzolo, G1
Bobrowska-Snarska, D1
Ostanek, L1
Nesterowicz, B1
Brzosko, M1
Ruud, E1
Holmstrøm, H1
Bergan, S1
Wesenberg, F1
Bairey, O1
Gabbay, U1
Blickstein, D1
Stark, P1
Prokocimer, M1
Epstein, O1
Shaklai, M1
Lahav, J1
Mauz-Körholz, C1
Junker, R2
Göbel, U1
Nowak-Göttl, U2
Heinecke, A1
von Kries, R1
Nürnberger, W1
Münchow, N1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Phase III Study Of Thalidomide And Prednisone As Maintenance Therapy Following Autologous Stem Cell Transplant in Patients With Multiple Myeloma[NCT00049673]Phase 3332 participants (Actual)Interventional2002-10-15Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for prednisone and Thrombophilia

ArticleYear
Intravenous immunoglobulin-associated thrombosis: is it such a rare event? Report of a pediatric case and of the Quebec Hemovigilance System.
    Transfusion, 2015, Volume: 55, Issue:3

    Topics: Adolescent; Aged; Autoimmune Diseases; Blood Safety; Contraceptives, Oral, Hormonal; Female; Headach

2015
Antiphospholipid syndrome in obstetrics.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2003, Volume: 9, Issue:2

    Topics: Abortion, Habitual; Abortion, Spontaneous; Adult; Annexin A5; Antibodies, Anticardiolipin; Anticoagu

2003

Trials

3 trials available for prednisone and Thrombophilia

ArticleYear
Thalidomide-prednisone maintenance following autologous stem cell transplant for multiple myeloma: effect on thrombin generation and procoagulant markers in NCIC CTG MY.10.
    British journal of haematology, 2015, Volume: 168, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Antithrombin III; Combined Modality The

2015
Effect of prednisone administration on coagulation variables in healthy Beagle dogs.
    Veterinary clinical pathology, 2011, Volume: 40, Issue:4

    Topics: Administration, Oral; Animals; Blood Coagulation; Dog Diseases; Dogs; Female; Glucocorticoids; Human

2011
Oral anticoagulation with warfarin is significantly influenced by steroids and CYP2C9 polymorphisms in children with cancer.
    Pediatric blood & cancer, 2008, Volume: 50, Issue:3

    Topics: Adolescent; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Aryl Hydrocarbon Hydroxy

2008

Other Studies

16 other studies available for prednisone and Thrombophilia

ArticleYear
Reproductive outcomes of women with recurrent pregnancy losses and repeated implantation failures are significantly improved with immunomodulatory treatment.
    Journal of reproductive immunology, 2021, Volume: 148

    Topics: Abortion, Habitual; Adolescent; Adult; Anti-Inflammatory Agents; Anticoagulants; Aspirin; Female; Fe

2021
Hypereosinophilic syndrome presenting acutely with neurologic signs.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2018, Volume: 120, Issue:5

    Topics: Aged; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Arthralgia; Chronic Disease; Chur

2018
Behcet's disease with major vascular involvement.
    BMJ case reports, 2013, Nov-08, Volume: 2013

    Topics: Adult; Aneurysm; Anti-Inflammatory Agents; Behcet Syndrome; Diagnosis, Differential; Hemoptysis; Hum

2013
Two children with steroid-responsive nephrotic syndrome complicated by cerebral venous sinus thrombosis.
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2015, Volume: 35, Issue:5

    Topics: Adult; Anticoagulants; Child, Preschool; Cyclosporine; Early Diagnosis; Heparin; Heparin, Low-Molecu

2015
Hypercoagulable states in patients with multiple myeloma can affect the thalidomide-associated venous thromboembolism.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2009, Volume: 20, Issue:5

    Topics: Activated Protein C Resistance; Angiogenesis Inhibitors; Anticoagulants; Antineoplastic Combined Che

2009
Prospective study of hemostatic alterations in children with acute lymphoblastic leukemia.
    American journal of hematology, 2010, Volume: 85, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Antithrombins; Asparaginase; Case-Contro

2010
"Idiopathic" intracranial hypertension caused by venous sinus thrombosis associated with contraceptive usage.
    Optometry (St. Louis, Mo.), 2010, Volume: 81, Issue:7

    Topics: Adolescent; Contraception Behavior; Diagnosis, Differential; Female; Glucocorticoids; Humans; Intrac

2010
[Necrotizing cellulitis as the first manifestation of disseminated cryptococcosis].
    Actas dermo-sifiliograficas, 2011, Volume: 102, Issue:4

    Topics: Aged; Amphotericin B; Anticoagulants; Antifungal Agents; Cellulitis; Cryptococcosis; Dermatomycoses;

2011
Acute bullous purpura associated with hyperhomocysteinemia and antiphospholipid antibodies.
    Journal of the American Academy of Dermatology, 2003, Volume: 49, Issue:2 Suppl Ca

    Topics: Acute Disease; Aged; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Biopsy, Needle; Female

2003
Predictors of cognitive dysfunction in patients with systemic lupus erythematosus.
    Neurology, 2005, Jan-25, Volume: 64, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Antiphospholipid; Aspirin; Autoant

2005
The course of anticardiolipin antibody levels under immunoadsorption therapy.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 46, Issue:3

    Topics: Abortion, Habitual; Abortion, Spontaneous; Adult; Antibodies, Anticardiolipin; Antibodies, Antinucle

2005
Remission of severe antiphospholipid syndrome associated with non-Hodgkin's B-cell lymphoma after combined treatment with rituximab and chemotherapy.
    Haematologica, 2005, Volume: 90 Suppl

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Anticoagulants; Antineoplastic Combi

2005
[Severe neurological and obstetrical complications in a patient with antiphospholipid syndrome].
    Polskie Archiwum Medycyny Wewnetrznej, 2006, Volume: 115, Issue:5

    Topics: Anti-Inflammatory Agents; Antibodies, Anticardiolipin; Anticoagulants; Antiphospholipid Syndrome; Fe

2006
Levels of proteins C and S do not decline subsequent to first line chemotherapy in lymphoma patients.
    Hematological oncology, 1997, Volume: 15, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; alpha-2-Antiplasmin; Antineoplastic Combined Chemotherap

1997
Prothrombotic risk factors in children with acute lymphoblastic leukemia treated with delayed E. coli asparaginase (COALL-92 and 97 protocols).
    Thrombosis and haemostasis, 2000, Volume: 83, Issue:6

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; C

2000
Thrombotic events revisited in children with acute lymphoblastic leukemia: impact of concomitant Escherichia coli asparaginase/prednisone administration.
    Thrombosis research, 2001, Aug-01, Volume: 103, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; D

2001