Page last updated: 2024-11-07

prednisone and Sterility, Male

prednisone has been researched along with Sterility, Male in 28 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Research Excerpts

ExcerptRelevanceReference
"Three patients with remission of Hodgkin's disease after involved-field (two) and extended-field (one) radiotherapy died from cardiovascular disease that could only be attributed to the prior radiotherapy."2.66Treatment of stages I and II Hodgkin's disease with three different therapeutic modalities. ( Caravelli, J; Cirrincione, C; Cunningham, I; Koziner, B; McCormick, B; Mertelsmann, R; Myers, J; Nisce, LZ; Redman, J; Straus, DJ, 1986)
"IBD increases the risk of pregnancy complications and adverse pregnancy outcomes."2.53Pregnancy and the Patient with Inflammatory Bowel Disease: Fertility, Treatment, Delivery, and Complications. ( Mahadevan, U; McConnell, RA, 2016)
"We followed-up 33 patients with non-Hodgkin's lymphoma or with Hodgkin's disease during the years 1987-1997 who were referred for semen cryopreservation."1.31Follow-up of sperm concentration and motility in patients with lymphoma. ( Botchan, A; Hauser, R; Paz, G; Tal, R; Yavetz, H; Yogev, L, 2000)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199016 (57.14)18.7374
1990's3 (10.71)18.2507
2000's5 (17.86)29.6817
2010's3 (10.71)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Amin, MSA1
Brunckhorst, O1
Scott, C1
Wrench, D1
Gleeson, M1
Kazmi, M1
Ahmed, K1
Paoli, D1
Rizzo, F1
Fiore, G1
Pallotti, F1
Pulsoni, A1
Annechini, G1
Lombardo, F1
Lenzi, A1
Gandini, L1
McConnell, RA1
Mahadevan, U1
Milardi, D1
Luca, G1
Grande, G1
Ghezzi, M1
Caretta, N1
Brusco, G1
De Filpo, G1
Marana, R1
Pontecorvi, A1
Calafiore, R1
Foresta, C2
Garolla, A2
Koyun, M1
Baysal, YE1
Usta, MF1
Akman, S1
Güven, AG1
Yu, AL1
Zhang, FZ1
Zhang, FX1
Tauchmanovà, L1
Alviggi, C1
Strina, I1
Colao, A1
Lombardi, G2
De Placido, G1
Rotoli, B1
Selleri, C1
Bonadonna, G1
Santoro, A1
Viviani, S1
Lombardi, C1
Ragni, G1
Ross, LS2
Dein, RA1
Mennuti, MT1
Kovach, P1
Gabbe, SG1
Hendry, WF1
Stedronska, J1
Parslow, J1
Hughes, L1
Silber, SJ1
Rodriguez-Rigau, LJ1
Keane, D1
Jenkins, DM1
Higgins, T1
O'Neill, M1
Mulcahy, MF1
Ferriss, JB1
Valentino, R1
Savastano, S1
Tommaselli, AP1
Scarpitta, MT1
Dorato, M1
Gigante, M1
Calvanese, E1
Carlino, M1
Tal, R1
Botchan, A1
Hauser, R1
Yogev, L1
Paz, G1
Yavetz, H1
Ulcova-Gallová, Z1
Bouse, V1
Rokyta, Z1
Krizanovská, K1
Baumgarten, SR1
Lindsay, GK1
Wise, GJ1
Augarten, A1
Weissenberg, R1
Pariente, C1
Sack, J1
Smarr, SC1
Wing, R1
Hammond, MG1
Koziner, B1
Myers, J1
Cirrincione, C1
Redman, J1
Cunningham, I1
Caravelli, J1
Nisce, LZ1
McCormick, B1
Straus, DJ1
Mertelsmann, R1
Conrad, MJ1
Rumke, P1
Koumans, J1
Hinkes, E1
Plotkin, D1
Van Thiel, DH1
Sherins, RJ2
Myers, GH1
De Vita, VT1
Arseneau, JC1
Canellos, GP1
DeVita, VT1
Bassili, F1
el-Alfi, OS1
Goldman, JA1
Schechter, A1
Eckerling, B1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Improvement in Pregnancy Outcomes in Immunologically Infertile Male Patients Undergoing Prednisolone Treatment and Conventional IVF Preceded by Sperm Penetration Assay: A Randomized Controlled Trial[NCT02935738]241 participants (Actual)Interventional2014-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Control and Treated Participants With Successful Live Births Following Conventional IVF or ICSI Cycles

Live birth rates in treated and control patients undergoing conventional IVF or ICSI cycles as determined by the sperm penetration assay (SPA) of hamster zone free ova (NCT02935738)
Timeframe: Nine months (pregnancy term) after the in vitro fertilization.

Interventionparticipants (Number)
Prednisolone Treated Men / Positive SPA / IVF18
Prednisolone Treated Men / Negative SPA / ICSI13
Control Men / Positive SPA / IVF8
Control Men / Negative SPA / ICSI9

Reviews

6 reviews available for prednisone and Sterility, Male

ArticleYear
ABVD and BEACOPP regimens' effects on fertility in young males with Hodgkin lymphoma.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2021, Volume: 23, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dacarbazine; Doxorubici

2021
Pregnancy and the Patient with Inflammatory Bowel Disease: Fertility, Treatment, Delivery, and Complications.
    Gastroenterology clinics of North America, 2016, Volume: 45, Issue:2

    Topics: Adalimumab; Aminosalicylic Acids; Anti-Bacterial Agents; Antibodies, Monoclonal; Biological Products

2016
Diagnosis and treatment of infertile men: a clinical perspective.
    The Journal of urology, 1983, Volume: 130, Issue:5

    Topics: Autoantibodies; Biopsy; Cimetidine; Fertilization in Vitro; Gonadal Steroid Hormones; Humans; Infect

1983
The reproductive potential of young men and women with Hodgkin's disease.
    Obstetrical & gynecological survey, 1984, Volume: 39, Issue:8

    Topics: Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Congenital Abnormalities; Female;

1984
Evaluation and treatment of the infertile man.
    Primary care, 1985, Volume: 12, Issue:4

    Topics: Chorionic Gonadotropin; Chromosome Aberrations; Chromosome Disorders; Clomiphene; Drug-Related Side

1985
Recently recognized complications of cancer chemotherapy.
    Annals of the New York Academy of Sciences, 1974, Volume: 230

    Topics: Antineoplastic Agents; Burkitt Lymphoma; Cyclophosphamide; Death, Sudden; Drug Therapy, Combination;

1974

Trials

4 trials available for prednisone and Sterility, Male

ArticleYear
Prednisone treatment in infertile patients with oligozoospermia and accessory gland inflammatory alterations.
    Andrology, 2017, Volume: 5, Issue:2

    Topics: Adult; Anti-Inflammatory Agents; Humans; Infertility, Male; Inflammation; Male; Middle Aged; Oligosp

2017
[Clinical observation on effect of combination of zhuanyindan and hormone in treating male infertility with positive antisperm antibody].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2004, Volume: 24, Issue:3

    Topics: Adult; Autoantibodies; Drug Therapy, Combination; Drugs, Chinese Herbal; Humans; Infertility, Male;

2004
Treatment of stages I and II Hodgkin's disease with three different therapeutic modalities.
    The American journal of medicine, 1986, Volume: 80, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Hodgkin Di

1986
Immunological aspermatogenesis in man. II. Response to corticosteroids in cases of non-obstructive azoospermia with a positive blastoid transformation test.
    Journal of reproduction and fertility, 1970, Volume: 21, Issue:1

    Topics: Adrenal Cortex Hormones; Adult; Antigens; Clinical Trials as Topic; Female; Humans; Infertility, Mal

1970

Other Studies

18 other studies available for prednisone and Sterility, Male

ArticleYear
Spermatogenesis in Hodgkin's lymphoma patients: a retrospective study of semen quality before and after different chemotherapy regimens.
    Human reproduction (Oxford, England), 2016, Volume: 31, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dacarbazine; Doxorubici

2016
Evaluation of reproductive functions in male adolescents following renal transplantation.
    Pediatric transplantation, 2009, Volume: 13, Issue:6

    Topics: Adolescent; Adrenal Cortex Hormones; Azathioprine; Cyclosporine; Follicle Stimulating Hormone; Human

2009
Cryptozoospermia with normal testicular function after allogeneic stem cell transplantation: a case report.
    Human reproduction (Oxford, England), 2007, Volume: 22, Issue:2

    Topics: Adult; Azoospermia; Biopsy, Fine-Needle; Graft vs Host Disease; Hematopoietic Stem Cell Transplantat

2007
Gonadal damage in Hodgkin's disease from cancer chemotherapeutic regimens.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1984, Volume: 7

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Castration; Dacarbazin

1984
The results of intermittent high dose steroid therapy for male infertility due to antisperm antibodies.
    Fertility and sterility, 1981, Volume: 36, Issue:3

    Topics: Adult; Autoantibodies; Humans; Infertility, Male; Male; Methylprednisolone; Middle Aged; Prednisone;

1981
Pregnancy after testicular transplant: importance of treating the couple.
    Fertility and sterility, 1980, Volume: 33, Issue:4

    Topics: Adult; Female; Humans; Infertility, Female; Infertility, Male; Male; Menstruation; Prednisone; Pregn

1980
The effect of intermittent steroid therapy on anti-sperm antibody levels.
    European journal of obstetrics, gynecology, and reproductive biology, 1995, Volume: 63, Issue:1

    Topics: Adult; Autoantibodies; Female; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Inferti

1995
Success of glucocorticoid replacement therapy on fertility in two adult males with 21-CAH homozygote classic form.
    Journal of endocrinological investigation, 1997, Volume: 20, Issue:11

    Topics: Adrenal Hyperplasia, Congenital; Adult; Cortisone; Dexamethasone; Drug Therapy, Combination; Follicl

1997
Follow-up of sperm concentration and motility in patients with lymphoma.
    Human reproduction (Oxford, England), 2000, Volume: 15, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cryopreservation; Daca

2000
Effect of corticosteroids on sperm antibody concentration in different biological fluids and on pregnancy outcome in immunologic infertility.
    Zentralblatt fur Gynakologie, 2000, Volume: 122, Issue:9

    Topics: Administration, Oral; Adult; Autoantibodies; Cervix Mucus; Dexamethasone; Female; Glucocorticoids; H

2000
Fertility problems in the renal transplant patient.
    The Journal of urology, 1977, Volume: 118, Issue:6

    Topics: Adult; Azathioprine; Follicle Stimulating Hormone; Humans; Infertility, Male; Kidney; Kidney Transpl

1977
Reversible male infertility in late onset congenital adrenal hyperplasia.
    Journal of endocrinological investigation, 1991, Volume: 14, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Child; F

1991
Effect of therapy on infertile couples with antisperm antibodies.
    American journal of obstetrics and gynecology, 1988, Volume: 158, Issue:4

    Topics: Adult; Antibodies; Cervix Mucus; Cytotoxicity Tests, Immunologic; Female; Fertilization in Vitro; He

1988
Sperm antibodies and their action upon human spermatozoa.
    Annales de l'Institut Pasteur, 1970, Volume: 118, Issue:4

    Topics: Adrenocorticotropic Hormone; Aged; Agglutination Tests; Antibody Formation; Autoantibodies; Cortison

1970
Male infertility caused by abnormal androgen production in the adrenal cortex.
    Andrologie, 1972, Volume: 4, Issue:4

    Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Adult; Estrogens; Follicle Stimulating Hormone; Gonado

1972
Reversible drug-induced sterility in a patient with acute leukemia.
    JAMA, 1973, Mar-26, Volume: 223, Issue:13

    Topics: Administration, Oral; Adolescent; Antineoplastic Agents; Cyclophosphamide; Drug Synergism; Follow-Up

1973
Evidence for a specific seminiferous tubular factor affecting follicle-stimulating hormone secretion in man.
    The Journal of clinical investigation, 1972, Volume: 51, Issue:4

    Topics: Adult; Biopsy; Cell Count; Clomiphene; Cyclophosphamide; Follicle Stimulating Hormone; Hodgkin Disea

1972
Carbohydrate metabolism in infertile and impotent males.
    Fertility and sterility, 1970, Volume: 21, Issue:5

    Topics: Carbohydrate Metabolism; Erectile Dysfunction; Glucose Tolerance Test; Humans; Infertility, Male; Ma

1970