Page last updated: 2024-11-07

prednisone and Refractory Anemia

prednisone has been researched along with Refractory Anemia in 7 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's2 (28.57)18.2507
2000's2 (28.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
FAIGEL, HC1
Bernini, JC1
Carrillo, JM1
Buchanan, GR1
Alexandrakis, MG1
Chatzivasili, A1
Stefanaki, K1
Eliopoulos, GD1
Litvak, D1
Kirsner, RS1
Pakdaman, NN1
Federman, DG1
GarcĂ­a Triana, Y1
Kyle, RA1
Stuart, RK1
Mangan, KF1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Use of Novel Therapies to Reconstitute Blood Cell Production and Promote Organ Performance Using Bone Marrow Failure as a Model: a Pilot, Phase I/II Study of the Amino Acid Leucine in the Treatment of Patients With Transfusion-Dependent Diamond Blackf[NCT01362595]Phase 1/Phase 255 participants (Actual)Interventional2013-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Response to Leucine in Transfusion Dependent Patients With Diamond Blackfan Anemia

"The primary outcome is the type of response observed at 9 months. Response to treatment can be one of the following:~Complete response (CR): Hb > 9 gm/dL and transfusion-independence as defined in DBA~Partial response (PR): Hb < 9 gm/dL and increased reticulocyte count to greater than baseline.~No response (NR): no change in transfusion requirements and no significant change reticulocyte count from baseline~Progression: worsening of disease as defined by the need for more frequent transfusions" (NCT01362595)
Timeframe: 9 Months

InterventionParticipants (Count of Participants)
Complete Hematologic ResponsePartial hematologic responseNo hematologic responseProgression
Leucine25360

Reviews

1 review available for prednisone and Refractory Anemia

ArticleYear
Diagnosis and management of multiple myeloma and related disorders.
    Progress in hematology, 1986, Volume: 14

    Topics: Alkylating Agents; Amyloidosis; Anemia; Anemia, Refractory; Animals; Antibodies, Monoclonal; Antineo

1986

Other Studies

6 other studies available for prednisone and Refractory Anemia

ArticleYear
CONGENITAL CYSTS OF THE RENAL MEDULLA. A CASE WITH SEVERE REFRACTORY ANEMIA.
    American journal of diseases of children (1960), 1964, Volume: 107

    Topics: Adolescent; Anemia; Anemia, Aplastic; Anemia, Refractory; Biopsy; Bone Marrow Examination; Child; Cy

1964
High-dose intravenous methylprednisolone therapy for patients with Diamond-Blackfan anemia refractory to conventional doses of prednisone.
    The Journal of pediatrics, 1995, Volume: 127, Issue:4

    Topics: Adolescent; Age of Onset; Anemia, Refractory; Anti-Infective Agents; Child, Preschool; Clinical Prot

1995
Co-existence of cutaneous true histiocytic lymphoma with refractory anaemia: report of a case.
    Haematologia, 2000, Volume: 30, Issue:1

    Topics: Aged; Anemia, Refractory; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy;

2000
Pyoderma gangrenosum and myelodysplastic syndrome.
    Southern medical journal, 2000, Volume: 93, Issue:9

    Topics: Anemia, Refractory; Anemia, Sideroblastic; Bone Marrow Examination; Glucocorticoids; Hematocrit; Hum

2000
[Appearance of different panmyelopathies in the same patient].
    Sangre, 1992, Volume: 37, Issue:2

    Topics: Adult; Anabolic Agents; Androgens; Anemia, Aplastic; Anemia, Refractory; Hemoglobinuria, Paroxysmal;

1992
Hematologic and cytogenetic remission of 5q-refractory anemia after syngeneic bone marrow transplantation.
    The American journal of medicine, 1986, Volume: 80, Issue:3

    Topics: Adult; Anemia, Refractory; Blood Transfusion; Bone Marrow Transplantation; Chromosome Aberrations; C

1986